• 2011
    • Jacobs, H., Moalin, M., van Gisbergen, M. W., Bast, A., van der Vijgh, W. J. F., & Haenen, G. R. M. M. (2011). An essential difference in the reactivity of the glutathione adducts of the structurally closely related flavonoids monoher and quercetin. Free Radical Biology and Medicine, 51(11), 2118-2123. https://doi.org/10.1016/j.freeradbiomed.2011.09.013
    • Jacobs, H., Koek, G. H., Peters, R., Moalin, M., Tack, J., van der Vijgh, W. J. F., Bast, A., & Haenen, G. R. M. M. (2011). Differences in pharmacological activities of the antioxidant flavonoid monoher in humans and mice are caused by variations in its metabolic profile. Clinical Pharmacology & Therapeutics, 90(6), 852-859. https://doi.org/10.1038/clpt.2011.200
    • Bartelds, B., Borgdorff, M. A., Smit-van Oosten, A., Takens, J., Boersma, B., Nederhoff, M. G., Elzenga, N. J., van Gilst, W. H., De Windt, L. J., & Berger, R. M. F. (2011). Differential responses of the right ventricle to abnormal loading conditions in mice: pressure vs. volume load. European journal of heart failure, 13(12), 1275-1282. https://doi.org/10.1093/eurjhf/hfr134
    • He, B. J., Joiner, M. A., Singh, M. V., Luczak, E. D., Swaminathan, P. D., Koval, O. M., Kutschke, W., Allamargot, C., Yang, J., Guan, X., Zimmerman, K., Grumbach, I. M., Weiss, R. M., Spitz, D. R., Sigmund, C. D., Blankesteijn, W. M., Heymans, S., Mohler, P. J., & Anderson, M. E. (2011). Oxidation of CaMKII determines the cardiotoxic effects of aldosterone. Nature Medicine, 17(12), 1610-U125. https://doi.org/10.1038/nm.2506
    • Heijnen, B. F. J., Peutz-Kootstra, C. J., Mullins, J. J., Janssen, B. J. A., & Struijker-Boudier, H. A. J. (2011). Transient renin-angiotensin system stimulation in an early stage of life causes sustained hypertension in rats. Journal of Hypertension, 29(12), 2369-2380. https://doi.org/10.1097/HJH.0b013e32834cfcf4
    • Armand, A.-S., Laziz, I., Djeghloul, D., Lecolle, S., Bertrand, A. T., Biondi, O., De Windt, L. J., & Chanoine, C. (2011). Apoptosis-Inducing Factor Regulates Skeletal Muscle Progenitor Cell Number and Muscle Phenotype. PLOS ONE, 6(11), 15. https://doi.org/10.1371/journal.pone.0027283
    • Moalin, M., van Strijdonck, G. P., Beckers, M., Hageman, G., Borm, P., Bast, A., & Haenen, G. R. M. M. (2011). A planar conformation and the hydroxyl groups in the b and c rings play a pivotal role in the antioxidant capacity of quercetin and quercetin derivatives. Molecules, 16(11), 9636-9650. https://doi.org/10.3390/molecules16119636
    • Laeremans, H., Hackeng, T. M., van Zandvoort, M. A. M. J., Thijssen, V. L. J. L., Janssen, B. J. A., Ottenheijm, H. C. J., Smits, J. F. M., & Blankesteijn, W. M. (2011). Blocking of Frizzled Signaling With a Homologous Peptide Fragment of Wnt3a/Wnt5a Reduces Infarct Expansion and Prevents the Development of Heart Failure After Myocardial Infarction. Circulation, 124(15), 1626-U107. https://doi.org/10.1161/CIRCULATIONAHA.110.976969
    • van Almen, G. C., Verhesen, W., van Leeuwen, R. E. W., van de Vrie, M., Eurlings, C., Schellings, M. W. M., Swinnen, M., Cleutjens, J. P. M., van Zandvoort, M. A. M. J., Heymans, S., & Schroen, B. (2011). MicroRNA-18 and microRNA-19 regulate CTGF and TSP-1 expression in age-related heart failure. Aging Cell, 10(5), 769-779. https://doi.org/10.1111/j.1474-9726.2011.00714.x
    • Wingler, K., Hermans, J. J. R., Schiffers, P., Moens, A. L., Paul, M., & Schmidt, H. H. H. W. (2011). NOX1, 2, 4, 5: counting out oxidative stress. British Journal of Pharmacology, 164(3), 866-883. https://doi.org/10.1111/j.1476-5381.2011.01249.x
    • Anson, N. M., Havenaar, R., Vaes, W., Coulier, L., Venema, K., Selinheimo, E., Bast, A., & Haenen, G. R. M. M. (2011). Effect of bioprocessing of wheat bran in wholemeal wheat breads on the colonic SCFA production in vitro and postprandial plasma concentrations in men. Food Chemistry, 128(2), 404-409. https://doi.org/10.1016/j.foodchem.2011.03.043
    • van Almen, G. C., Swinnen, M., Carai, P., Verhesen, W., Cleutjens, J. P. M., D'hooge, J., Verheyen, F. K., Pinto, Y. M., Schroen, B., Carmeliet, P., & Heymans, S. (2011). Absence of thrombospondin-2 increases cardiomyocyte damage and matrix disruption in doxorubicin-induced cardiomyopathy. Journal of Molecular and Cellular Cardiology, 51(3), 318-328. https://doi.org/10.1016/j.yjmcc.2011.05.010
    • Maitland-van der Zee, A.-H., van Wieren-de Wijer, D. B. M. A., de Boer, A., Kroon, A. A., de Leeuw, P. W., Schiffers, P., Janssen, R. G. J. H., Psaty, B. M., Duijn, C. M. V., Stricker, B. H. C., & Klungel, O. H. (2011). Genetic variation in the renin-angiotensin system, use of renin-angiotensin system inhibitors and the risk of myocardial infarction. Journal of the Renin-angiotensin-aldosterone System, 12(3), 208-214. https://doi.org/10.1177/1470320310391834
    • Olieslagers, S., Pardali, E., Tchaikovski, V., ten Dijke, P., & Waltenberger, J. (2011). TGF-beta 1/ALK5-induced monocyte migration involves PI3K and p38 pathways and is not negatively affected by diabetes mellitus. Cardiovascular Research, 91(3), 510-518. https://doi.org/10.1093/cvr/cvr100
    • Spijkers, L. J. A., van den Akker, R. F. P., Janssen, B. J. A., Debets, J. J., De Mey, J. G. R., Stroes, E. S. G., van den Born, B.-J. H., Wijesinghe, D. S., Chalfant, C. E., MacAleese, L., Eijkel, G. B., Heeren, R. M. A., Alewijnse, A. E., & Peters, S. L. M. (2011). Hypertension Is Associated with Marked Alterations in Sphingolipid Biology: A Potential Role for Ceramide. PLOS ONE, 6(7), 9. https://doi.org/10.1371/journal.pone.0021817
    • Meens, M. J. P. M. T., Mattheij, N. J. A., Nelissen, J., Lemkens, P., Compeer, M. G., Janssen, B. J. A., & De Mey, J. G. R. (2011). Calcitonin Gene-Related Peptide Terminates Long-Lasting Vasopressor Responses to Endothelin 1 In Vivo. Hypertension, 58(1), 99-U181. https://doi.org/10.1161/HYPERTENSIONAHA.110.169128
    • Verkaar, F., van der Stelt, M., Blankesteijn, W. M., van der Doelen, A. A., & Zaman, G. J. R. (2011). Discovery of Novel Small Molecule Activators of beta-Catenin Signaling. PLOS ONE, 6(4), 7. https://doi.org/10.1371/journal.pone.0019185
    • Verkaar, F., van der Doelen, A. A., Smits, J. F. M., Blankesteijn, W. M., & Zaman, G. J. R. (2011). Inhibition of Wnt/beta-Catenin Signaling by p38 MAP Kinase Inhibitors Is Explained by Cross-Reactivity with Casein Kinase I delta/epsilon. Chemistry & Biology, 18(4), 485-494. https://doi.org/10.1016/j.chembiol.2011.01.015
    • el Azzouzi, H., Leptidis, S., Bourajjaj, M., Armand, A.-S., van der Nagel, R., van Bilsen, M., Martins, P. A. D. C., & De Windt, L. J. (2011). Peroxisome Proliferator-activated Receptor (PPAR) Gene Profiling Uncovers Insulin-like Growth Factor-1 as a PPAR alpha Target Gene in Cardioprotection. Journal of Biological Chemistry, 286(16), 14598-14607. https://doi.org/10.1074/jbc.M111.220525
    • Perino, A., Ghigo, A., Ferrero, E., More, F., Santulli, G., Baillie, G. S., Damilano, F., Dunlop, A. J., Pawson, C., Walser, R., Levi, R., Altruda, F., Silengo, L., Langeberg, L. K., Neubauer, G., Heymans, S., Lembo, G., Wymann, M. P., Wetzker, R., ... Hirsch, E. (2011). Integrating Cardiac PIP3 and cAMP Signaling through a PKA Anchoring Function of p110 gamma. Molecular Cell, 42(1), 84-95. https://doi.org/10.1016/j.molcel.2011.01.030
    • Mischke, K., Knackstedt, C., Fache, K., Reith, S., Rana, O., Saygili, E., Gemein, C., Becker, M., Marx, N., & Schauerte, P. (2011). Electrical remodelling in cardiac resynchronization therapy: decrease in intrinsic QRS duration. Acta Cardiologica, 66(2), 175-180. https://doi.org/10.1080/AC.66.2.2071248
    • Muzzarelli, S., Stricker, B. H., Pfister, O., Foglia, P., Moschovitis, G., Mombelli, G., & Brunner-La Rocca, H. (2011). Individual dosage of digoxin in patients with heart failure. QJM: An International Journal of Medicine, 104(4), 309-317. https://doi.org/10.1093/qjmed/hcq196
    • van de Vrie, M., Heymans, S., & Schroen, B. (2011). MicroRNA Involvement in Immune Activation During Heart Failure. Cardiovascular Drugs and Therapy, 25(2), 161-170. https://doi.org/10.1007/s10557-011-6291-y
    • Czepluch, F. S., Olieslagers, S., van Hulten, R., Voo, S. A., & Waltenberger, J. (2011). VEGF-A-induced chemotaxis of CD16+monocytes is decreased secondary to lower VEGFR-1 expression. Atherosclerosis, 215(2), 331-338. https://doi.org/10.1016/j.atherosclerosis.2011.01.004
    • Leventhal, M. E., Denhaerynck, K., Brunner-La Rocca, H.-P., Burnand, B., Conca, A., Bernasconi, A. T., Mahrer-Imhof, R., Froelicher, E. S., & De Geest, S. (2011). Swiss Interdisciplinary Management Programme for Heart Failure (SWIM-HF). Swiss Medical Weekly, 141, 10. https://doi.org/10.4414/smw.2011.13171
    • Snoeijs, M. G., van Bijnen, A., Swennen, E. L., Haenen, G. R. M. M., Roberts, L. J., Christiaans, M. H., Peppelenbosch, A. G., Buurman, W. A., & van Heurn, L. W. E. (2011). Tubular Epithelial Injury and Inflammation After Ischemia and Reperfusion in Human Kidney Transplantation. Annals of Surgery, 253(3), 598-604. https://doi.org/10.1097/SLA.0b013e31820d9ae9
    • Jacobs, H., Bast, A., Peters, G. J., van der Vijgh, W. J. F., & Haenen, G. R. M. M. (2011). The semisynthetic flavonoid monoHER sensitises human soft tissue sarcoma cells to doxorubicin-induced apoptosis via inhibition of nuclear factor-kappaB. British Journal of Cancer, 104(3), 437-440. https://doi.org/10.1038/sj.bjc.6606065
    • Bläuer, C., Mahrer-Imhof, R., Brunner-La Rocca, H., Mueller, C. P., Eze, G., Milbich, I., & Spirig, R. (2011). Development and Implementation of a multidisciplinary nurse-led educational programme for inpatients with heart failure: The Basel-HF-Programme: Entwicklung und Implementierung eines multidisziplinären pflegegeleiteten Programms zur stationären Betreuung von Patientinnen und Patienten mit Herzinsuffizienz: Das Basler HI-Programm. Pflege, 24(1), 29-41. https://doi.org/10.1024/1012-5302/a000089
    • Snoeijs, M. G., Vaahtera, L., de Vries, E. E., Schurink, G. W. H., Haenen, G. R. M. M., Peutz-Kootstra, C. J., Buurman, W. A., van Heurn, L. W. E., & Parkkinen, J. (2011). Addition of a water-soluble propofol formulation to preservation solution in experimental kidney transplantation. Transplantation, 92(3), 296-302. https://doi.org/10.1097/TP.0b013e3182247b78
    • Mateo Anson, N., Aura, A. M., Selinheimo, E., Mattila, I., Poutanen, K., van den Berg, R., Havenaar, R., Bast, A., & Haenen, G. R. M. M. (2011). Bioprocessing of Wheat Bran in Whole Wheat Bread Increases the Bioavailability of Phenolic Acids in Men and Exerts Antiinflammatory Effects ex Vivo.Journal of Nutrition, 141(1), 137-143. https://doi.org/10.3945/jn.110.127720
    • Jacobs, H., Peters, R., den Hartog, G. J. M., van der Vijgh, W. J. F., Bast, A., & Haenen, G. R. M. M. (2011). Identification of the Metabolites of the Antioxidant Flavonoid 7-Mono-O-({beta}-hydroxyethyl)-rutoside in Mice.Drug Metabolism and Disposition, 39(5), 750-756. https://doi.org/10.1124/dmd.110.036525
    • Linschooten, J. O., Laubenthal, J., Cemeli, E., Baumgartner, A., Anderson, D., Sipinen, V. E., Brunborg, G., Haenen, G. R. M. M., Fthenou, E., Briedé, J. J., van Schooten, F. J., & Godschalk, R. W. L. (2011). Incomplete protection of genetic integrity of mature spermatozoa against oxidative stress.Reproductive Toxicology, 32(1), 106-111. https://doi.org/10.1016/j.reprotox.2011.05.004
    • Boots, A. W., Drent, M., de Boer, V. C., Bast, A., & Haenen, G. R. M. M. (2011). Quercetin reduces markers of oxidative stress and inflammation in sarcoidosis. Clinical Nutrition, 30(4), 506-512. https://doi.org/10.1016/j.clnu.2011.01.010
    • Nabben, M., Shabalina, I. G., Kornips, C. F. P., Van Beurden, D., Cannon, B., Schrauwen, P., Nedergaard, J., & Hoeks, J. (2011). Uncoupled respiration, ROS production, acute lipotoxicity and oxidative damage in isolated skeletal muscle mitochondria from UCP3-ablated mice.Biochimica et Biophysica Acta-bioenergetics, 1807(9), 1095-1105. https://doi.org/10.1016/j.bbabio.2011.04.003
    • Eschenhagen, T., Force, T., Ewer, M. S., De Keulenaer, G. W., Suter, T. M., Anker, S. D., Avkiran, M., de Azambuja, E., Balligand, J. L., Brutsaert, D. L., Condorelli, G., Hansen, A., Heymans, S., Hill, J. A., Hirsch, E., Hilfiker-Kleiner, D., Janssens, S., de Jong, S., Neubauer, G., ... Shah, A. M. (2011). Cardiovascular side effects of cancer therapies: a position statement from the Heart Failure Association of the European Society of Cardiology. European journal of heart failure, 13(1), 1-10. https://doi.org/10.1093/eurjhf/hfq213
    • Czepluch, F. S., Barres, R., Caidahl, K., Olieslagers, S., Krook, A., Rickenlund, A., Zierath, J. R., & Waltenberger, J. (2011). Strenuous physical exercise adversely affects monocyte chemotaxis. Thrombosis and Haemostasis, 105(1), 122-130. https://doi.org/10.1160/TH10-06-0363
    • Alzand, B. S. N., Mihl, C., & La Rocca, H. P. B. (2011). Dehydration with High Natriuretic Peptide Levels! A Word of Caution. Cardiology, 118(2), 75-78. https://doi.org/10.1159/000326855
    • Constantinides, C., Mean, R., & Janssen, B. J. (2011). Effects of isoflurane anesthesia on the cardiovascular function of the C57BL/6 mouse. Ilar Journal, 52(3), e21-31.
  • 2010
    • Rother, M., Krohn, S., Kania, G., Vanhoutte, D., Eisenreich, A., Wang, X., Westermann, D., Savvatis, K., Dannemann, N., Skurk, C., Hilfiker-Kleiner, D., Cathomen, T., Fechner, H., Rauch, U., Schultheiss, H.-P., Heymans, S., Eriksson, U., Scheibenbogen, C., & Poller, W. (2010). Matricellular Signaling Molecule CCN1 Attenuates Experimental Autoimmune Myocarditis by Acting as a Novel Immune Cell Migration Modulator. Circulation, 122(25), 2688-2698. https://doi.org/10.1161/CIRCULATIONAHA.110.945261
    • Kaiser, C. A., Galatius, S., Erne, P., Eberli, F., Alber, H., Rickli, H., Pedrazzini, G., Hornig, B., Bertel, O., Bonetti, P., De Servi, S., Brunner-La Rocca, H.-P., Ricard, I., & Pfisterer, M. E. (2010). Drug-Eluting versus Bare-Metal Stents in Large Coronary Arteries. New England Journal of Medicine, 363(24), 2310-2319. https://doi.org/10.1056/NEJMoa1009406
    • Martins, P. A. D. C., Salic, K., Gladka, M. M., Armand, A.-S., Leptidis, S., el Azzouzit, H., Hansen, A., Coenen-de Roo, C. J., Bierhuizen, M. F. A., van der Nagel, R., van Kuik, J., de Weger, R. A., de Bruin, A., Condorelli, G., Arbones, M. L., Eschenhagen, T., & De Windt, L. J. (2010). MicroRNA-199b targets the nuclear kinase Dyrk1a in an auto-amplification loop promoting calcineurin/NFAT signalling. Nature Cell Biology, 12(12), 1220-U231. https://doi.org/10.1038/ncb2126
    • Donners, M. P. C., Wolfs, I. M. J., Olieslagers, S., Mohammadi-Motahhari, Z., Tchaikovski, V., Heeneman, S., van Buul, J. D., Caolo, V., Molin, D. G. M., Post, M. J., & Waltenberger, J. (2010). A Disintegrin and Metalloprotease 10 Is a Novel Mediator of Vascular Endothelial Growth Factor: Induced Endothelial Cell Function in Angiogenesis and Is Associated With Atherosclerosis. Arteriosclerosis Thrombosis and Vascular Biology, 30(11), 2188-U382. https://doi.org/10.1161/ATVBAHA.110.213124
    • van den Berg, S. A., Nabben, M., Bijland, S., Voshol, P. J., van Klinken, J. B., Havekes, L. M., Romijn, H. A., Hoeks, J., Hesselink, M. K., Schrauwen, P., & van Dijk, K. W. (2010). High levels of whole-body energy expenditure are associated with a lower coupling of skeletal muscle mitochondria in C57B1/6 mice. Metabolism-Clinical and Experimental, 59(11), 1612-1618. https://doi.org/10.1016/j.metabol.2010.03.008
    • den Hengst, W. A., Gielis, J. F., Lin, J. Y., Van Schil, P. E. Y., De Windt, L. J., & Moens, A. L. (2010). Lung ischemia-reperfusion injury: a molecular and clinical view on a complex pathophysiological process. American Journal of Physiology-heart and Circulatory Physiology, 299(5), H1283-H1299. https://doi.org/10.1152/ajpheart.00251.2010
    • Dargaud, Y., Spronk, H. M. H., Leenders, P., Hemker, H. C., & Ten Cate, H. (2010). Monitoring platelet dependent thrombin generation in mice. Thrombosis Research, 126(5), 436-441. https://doi.org/10.1016/j.thromres.2010.08.007
    • Maeder, M. T., Thompson, B. R., Brunner-La Rocca, H.-P., & Kaye, D. M. (2010). Hemodynamic Basis of Exercise Limitation in Patients With Heart Failure and Normal Ejection Fraction. Journal of the American College of Cardiology, 56(11), 855-863. https://doi.org/10.1016/j.jacc.2010.04.040
    • Daniels, A., van Bilsen, M., Janssen, B. J. A., Brouns, A. E., Cleutjens, J. P. M., Roemen, T. H., Schaart, G., van der Velden, J., van der Vusse, G. J., & van Nieuwenhoven, F. A. (2010). Impaired cardiac functional reserve in type 2 diabetic db/db mice is associated with metabolic, but not structural, remodelling. Acta Physiologica, 200(1), 11-22. https://doi.org/10.1111/j.1748-1716.2010.02102.x
    • Leenders, J. J., Wijnen, W. J., Hiller, M., van der Made, I., Lentink, V., van Leeuwen, R. E. W., Herias, V., Pokharel, S., Heymans, S., de Windt, L. J., Hoydal, M. A., Pinto, Y. M., & Creemers, E. E. (2010). Regulation of Cardiac Gene Expression by KLF15, a Repressor of Myocardin Activity. Journal of Biological Chemistry, 285(35), 27449-27456. https://doi.org/10.1074/jbc.M110.107292