Murdoch, C. E., Chaubey, S., Zeng, L., Yu, B., Ivetic, A., Walker, S. J., Vanhoutte, D., Heymans, S., Grieve, D. J., Cave, A. C., Brewer, A. C., Zhang, M., & Shah, A. M. (2014). Endothelial NADPH Oxidase-2 Promotes Interstitial Cardiac Fibrosis and Diastolic Dysfunction Through Proinflammatory Effects and Endothelial-Mesenchymal Transition. Journal of the American College of Cardiology, 63(24), 2734-2741. https://doi.org/10.1016/j.jacc.2014.02.572

Troughton, R. W., Frampton, C. M., Brunner-La Rocca, H.-P., Pfisterer, M., Eurlings, L. W. M., Erntell, H., Persson, H., O'Connor, C. M., Moertl, D., Karlstrom, P., Dahlstrom, U., Gaggin, H. K., Januzzi, J. L., Berger, R., Richards, A. M., Pinto, Y. M., & Nicholls, M. G. (2014). Effect of B-type natriuretic peptide-guided treatment of chronic heart failure on total mortality and hospitalization: an individual patient meta-analysis. European Heart Journal, 35(23), 1559-1567. https://doi.org/10.1093/eurheartj/ehu090

Lemmens, K. J., van de Wier, B., Vaes, N., Ghosh, M., van Zandvoort, M. A., van der Vijgh, W., Bast, A., & Haenen, G. R. (2014). The flavonoid 7-mono-O-(beta-hydroxyethyl)-rutoside is able to protect endothelial cells by a direct antioxidant effect. Toxicology in Vitro, 28(4), 538-543. https://doi.org/10.1016/j.tiv.2013.12.019

Bekkers, S. C. A. M., & Brunner-La Rocca, H. P. (2014). Elderly primary care hypertension patients-who to refer for echocardiography?Netherlands Heart Journal, 22(5), 231-233. https://doi.org/10.1007/s12471-014-0550-z

Leite-Moreira, A. F., Lourenco, A. P., Balligand, J.-L., Bauersachs, J., Clerk, A., De Windt, L. J., Heymans, S., Hilfiker-Kleiner, D., Hirsch, E., Iaccarino, G., Kaminski, K. A., Knoell, R., Mayr, M., Tarone, G., Thum, T., & Tocchetti, C. G. (2014). ESC Working Group on Myocardial Function Position Paper: how to study the right ventricle in experimental models. European journal of heart failure, 16(5), 509-518. https://doi.org/10.1002/ejhf.66

Tarone, G., Balligand, J.-L., Bauersachs, J., Clerk, A., De Windt, L., Heymans, S., Hilfiker-Kleiner, D., Hirsch, E., Iaccarino, G., Knoell, R., Leite-Moreira, A. F., Lourenco, A. P., Mayr, M., Thum, T., & Tocchetti, C. G. (2014). Targeting myocardial remodelling to develop novel therapies for heart failure A position paper from the Working Group on Myocardial Function of the European Society of Cardiology. European journal of heart failure, 16(5), 494-508. https://doi.org/10.1002/ejhf.62

Milenkovic, D., Vanden Berghe, W., Boby, C., Leroux, C., Declerck, K., Szarc Vel Szic, K., Heyninck, K., Laukens, K., Bizet, M., Defrance, M., Dedeurwaerder, S., Calonne, E., Fuks, F., Haegeman, G., Haenen, G. R., Bast, A., & Weseler, A. R. (2014). Dietary Flavanols Modulate the Transcription of Genes Associated with Cardiovascular Pathology without Changes in Their DNA Methylation State. PLOS ONE, 9(4), Article e95527. https://doi.org/10.1371/journal.pone.0095527

Poels, E. M., Bitsch, N., Slenter, J. M., Kooi, M. E., de Theije, C. C., De Windt, L. J., van Empel, V. P., & da Costa Martins, P. A. (2014). Supplementing exposure to hypoxia with a copper depleted diet does not exacerbate right ventricular remodeling in mice. PLOS ONE, 9(4), Article 92983. https://doi.org/10.1371/journal.pone.0092983

Kriemler, S., Buergi, F., Wick, C., Wick, B., Keller, M., Wiget, U., Schindler, C., Kaufmann, B. A., Kohler, M., Bloch, K., & Brunner-La Rocca, H.-P. (2014). Prevalence of Acute Mountain Sickness at 3500 m Within and Between Families: A Prospective Cohort Study. High Altitude Medicine & Biology, 15(1), 28-38. https://doi.org/10.1089/ham.2013.1073

Daskalopoulos, E. P., Hermans, K. C. M., & Blankesteijn, M. (2014). Cardiac (myo)fibroblast: Novel Strategies for its Targeting Following Myocardial Infarction. Current Pharmaceutical Design, 20(12), 1987-2002. https://doi.org/10.2174/13816128113199990452

Beaumont, J., Lopez, B., Hermida, N., Schroen, B., Jose, G. S., Heymans, S., Valencia, F., Jose Gomez-Doblas, J., De Teresa, E., Diez, J., & Gonzalez, A. (2014). microRNA-122 down-regulation may play a role in severe myocardial fibrosis in human aortic stenosis through TGF-beta(1) up-regulation. Clinical Science, 126(7-8), 497-506. https://doi.org/10.1042/CS20130538

Hendriks, J. M. L., Vrijhoef, H. J. M., Crijns, H. J. G. M., & Brunner-La Rocca, H. P. (2014). The effect of a nurse-led integrated chronic care approach on quality of life in patients with atrial fibrillation. EP Europace, 16(4), 491-499. https://doi.org/10.1093/europace/eut286

Kelly, E. R., Plat, J., Haenen, G. R., Kijlstra, A., & Berendschot, T. T. (2014). The effect of modified eggs and an egg-yolk based beverage on serum lutein and zeaxanthin concentrations and macular pigment optical density: results from a randomized trial. PLOS ONE, 9(3), Article 92659. https://doi.org/10.1371/journal.pone.0092659

Sanders-van Wijk, S., van Empel, V., Knackstedt, C., & Brunner-La Rocca, H.-P. (2014). Heart failure and COPD: Time to SHIFT?International Journal of Cardiology, 172(2), 293-294. https://doi.org/10.1016/j.ijcard.2013.12.285

Roncarati, R., Anselmi, C. V., Losi, M. A., Papa, L., Cavarretta, E., Martins, P. D. C., Contaldi, C., Jotti, G. S., Franzone, A., Galastri, L., Latronico, M. V. G., Imbriaco, M., Esposito, G., De Windt, L., Betocchi, S., & Condorelli, G. (2014). Circulating miR-29a, Among Other Up-Regulated MicroRNAs, Is the Only Biomarker for Both Hypertrophy and Fibrosis in Patients With Hypertrophic Cardiomyopathy. Journal of the American College of Cardiology, 63(9), 920-927. https://doi.org/10.1016/j.jacc.2013.09.041

Papageorgiou, A.-P., & Heymans, S. (2014). Peroxidasin-like protein: expanding the horizons of matrix biology. Cardiovascular Research, 101(3), 342-343. https://doi.org/10.1093/cvr/cvu017

Peeters, J. M. P. W. U., Sanders-van Wijk, S., Bektas, S., Knackstedt, C., Rickenbacher, P., Nietlispach, F., Handschin, R., Maeder, M. T., Muzzarelli, S. F., Pfisterer, M. E., & Brunner-La Rocca, H. P. (2014). Biomarkers in outpatient heart failure management; Are they correlated to and do they influence clinical judgment?Netherlands Heart Journal, 22(3), 115-121. https://doi.org/10.1007/s12471-013-0503-y

Heijnen, B. F. J., Pelkmans, L. P. J., Danser, A. H. J., Garrelds, I. M., Mullins, J. J., De Mey, J. G. R., Struijker-Boudier, H. A. J., & Janssen, B. J. A. (2014). Cardiac remodeling during and after renin-angiotensin system stimulation in Cyp1a1-Ren2 transgenic rats. Journal of the Renin-angiotensin-aldosterone System, 15(1), 69-81. https://doi.org/10.1177/1470320313480537

Rienks, M., Papageorgiou, A.-P., Frangogiannis, N. G., & Heymans, S. (2014). Myocardial Extracellular Matrix An Ever-Changing and Diverse Entity. Circulation Research, 114(5), 872-888. https://doi.org/10.1161/CIRCRESAHA.114.302533

Meyer, U., Schindler, C., Zahner, L., Ernst, D., Hebestreit, H., van Mechelen, W., Rocca, H.-P. B.-L., Probst-Hensch, N., Puder, J. J., & Kriemler, S. (2014). Long-Term Effect of a School-Based Physical Activity Program (KISS) on Fitness and Adiposity in Children: A Cluster-Randomized Controlled Trial. PLOS ONE, 9(2), Article e87929. https://doi.org/10.1371/journal.pone.0087929

Hazebroek, M. R., Everaerts, K., & Heymans, S. (2014). Diagnostic approach of myocarditis: strike the golden mean. Netherlands Heart Journal, 22(2), 80-84. https://doi.org/10.1007/s12471-013-0499-3

Van Empel, V. P. M., Kaufmann, B. A., Bernheim, A. M., Goetschalckx, K., Min, S. Y., Muzzarelli, S., Pfisterer, M. E., Kiencke, S., Maeder, M. T., & Brunner-La Rocca, H.-P. (2014). Interaction Between Pulmonary Hypertension and Diastolic Dysfunction in an Elderly Heart Failure Population. Journal of Cardiac Failure, 20(2), 98-104. https://doi.org/10.1016/j.cardfail.2013.12.010

Burkard, T., Pfister, O., Rickli, H., Follath, F., Hack, D., Zaker, R., Pittl, U., Handschin, R., Pfisterer, M., & Brunner-La Rocca, H. .-P. (2014). Prognostic impact of systemic inflammatory diseases in elderly patients with congestive heart failure. QJM: An International Journal of Medicine, 107(2), 131-138. https://doi.org/10.1093/qjmed/hct205

Heijnen, B. F. J., Van Essen, H., Schalkwijk, C. G., Janssen, B. J. A., & Struijker-Boudier, H. A. J. (2014). Renal inflammatory markers during the onset of hypertension in spontaneously hypertensive rats. Hypertension Research, 37(2), 100-109. https://doi.org/10.1038/hr.2013.99

Napp, A., Joosten, S., Stunder, D., Knackstedt, C., Zink, M., Bellmann, B., Marx, N., Schauerte, P., & Silny, J. (2014). Electromagnetic Interference With Implantable Cardioverter-Defibrillators at Power Frequency An In Vivo Study. Circulation, 129(4), 441-450. https://doi.org/10.1161/CIRCULATIONAHA.113.003081

van Bilsen, M., Daniels, A., Brouwers, O., Janssen, B. J. A., Derks, W. J. A., Brouns, A. E., Munts, C., Schalkwijk, C. G., van der Vusse, G. J., & van Nieuwenhoven, F. A. (2014). Hypertension Is a Conditional Factor for the Development of Cardiac Hypertrophy in Type 2 Diabetic Mice. PLOS ONE, 9(1), Article e85078. https://doi.org/10.1371/journal.pone.0085078

Sthijns, M. M., Randall, M. J., Bast, A., & Haenen, G. R. (2014). Adaptation to acrolein through upregulating the protection by glutathione in human bronchial epithelial cells: The materialization of the hormesis concept.Biochemical and Biophysical Research Communications, 446(4), 1029-1034. https://doi.org/10.1016/j.bbrc.2014.03.081

Hazebroek, M. R., van Paassen, P., Weerwind, P. W., Cooper, L. T. . J., Uriel, N., Caliskan, K., de Vries, B., Maessen, J. G., Autschbach, R., Heymans, S., & Donker, D. W. (2014). A passionate endurance cyclist ultimately survives sudden death in right ventricular giant cell myocarditis. International Journal of Cardiology, 170(3), E74-E75. https://doi.org/10.1016/j.ijcard.2013.11.028

Hazewindus, M., Haenen, G. R., Weseler, A. R., & Bast, A. (2014). Protection against Chemotaxis in the Anti-Inflammatory Effect of Bioactives from Tomato Ketchup. PLOS ONE, 9(12), Article e114387. https://doi.org/10.1371/journal.pone.0114387

Marsch, E., Theelen, T. L., Demandt, J. A., Jeurissen, M., van Gink, M., Verjans, R., Janssen, A., Cleutjens, J. P., Meex, S. J., Donners, M. M., Haenen, G., Schalkwijk, C. G., Dubois, L. J., Lambin, P., Mallat, Z., Gijbels, M. J., Heemskerk, J. W., Fisher, E. A., Biessen, E. A., ... Sluimer, J. C. (2014). Reversal of hypoxia in murine atherosclerosis prevents necrotic core expansion by enhancing efferocytosis. Arteriosclerosis Thrombosis and Vascular Biology, 34(12), 2545-2553. https://doi.org/10.1161/ATVBAHA.114.304023

Ruijters, E. J., Haenen, G. R., Weseler, A. R., & Bast, A. (2014). The cocoa flavanol (-)-epicatechin protects the cortisol response.Pharmacological Research, 79, 28-33. https://doi.org/10.1016/j.phrs.2013.11.004

Lemmens, K. J., Vrolijk, M. F., Bouwman, F. G., van der Vijgh, W. J., Bast, A., & Haenen, G. R. (2014). The Minor Structural Difference between the Antioxidants Quercetin and 4'O-Methylquercetin Has a Major Impact on Their Selective Thiol. International journal of molecular sciences, 15(5), 7475-7484. https://doi.org/10.3390/ijms15057475

Brouwers, O., Niessen, P. M. G., Miyata, T., Ostergaard, J. A., Flyvbjerg, A., Peutz-Kootstra, C. J., Sieber, J., Mundel, P. H., Brownlee, M., Janssen, B. J. A., De Mey, J. G. R., Stehouwer, C. D. A., & Schalkwijk, C. G. (2014). Glyoxalase-1 overexpression reduces endothelial dysfunction and attenuates early renal impairment in a rat model of diabetes. Diabetologia, 57(1), 224-235. https://doi.org/10.1007/s00125-013-3088-5

Sanders-van Wijk, S., Maeder, M. T., Nietlispach, F., Rickli, H., Estlinbaum, W., Erne, P., Rickenbacher, P., Peter, M., Pfisterer, M. P., & Brunner-La Rocca, H.-P. (2014). Long-Term Results of Intensified, N-Terminal-Pro-B-Type Natriuretic Peptide-Guided Versus Symptom-Guided Treatment in Elderly Patients With Heart Failure Five-Year Follow-Up From TIME-CHF. Circulation-Heart Failure, 7(1), 131-139. https://doi.org/10.1161/CIRCHEARTFAILURE.113.000527

Hohl, M., Ardehali, H., Azuaje, F. J., Breckenridge, R. A., Doehner, W., Eaton, P., Ehret, G. B., Fujita, T., Gaetani, R., Giacca, M., Hasenfuss, G., Heymans, S., Leite-Moreira, A. F., Linke, W. A., Linz, D., Lyon, A., Mamas, M. A., Oresic, M., Papp, Z., ... Maack, C. (2014). Meeting highlights from the 2013 European Society of Cardiology Heart Failure Association Winter Meeting on Translational Heart Failure Research. European journal of heart failure, 16(1), 6-14. https://doi.org/10.1002/ejhf.10

Mafi Rad, M., Blaauw, Y., Debie, L., Brunner-La Rocca, H., & Vernooy, K. (2014). Evaluation of Left Ventricular Endocardial Cardiac Resynchronization Therapy in a Non-responder with Ventricular Arrhythmias. Indian pacing and electrophysiology journal, 14(1), 32-6. https://doi.org/10.1016/S0972-6292(16)30713-6

van Dongen, M., van Kraaij, D., Schalla, S., Brunner-La Rocca, H., & Driessen, R. (2014). Severe mitral regurgitation caused by eosinophilic endocarditis. Journal of Cardiology Cases, 10(3). https://doi.org/10.1016/j.jccase.2014.05.012

van Buchem, M. A., Biessels, G. J., la Rocca, H. P. B., de Craen, A. J. M., van der Flier, W. M., Ikram, M. A., Kappelle, L. J., Koudstaal, P. J., Mooijaart, S. P., Niessen, W., van Oostenbrugge, R., de Roos, A., van Rossum, A. C., & Daemen, M. J. A. P. (2014). The Heart-Brain Connection: A Multidisciplinary Approach Targeting a Missing Link in the Pathophysiology of Vascular Cognitive Impairment. Journal of Alzheimer's Disease, 42, S443-S451. https://doi.org/10.3233/JAD-141542

Arends, S. J., Damoiseaux, J. G., Duijvestijn, A. M., Debrus-Palmans, L., Vroomen, M., Boomars, K. A., Brunner-La Rocca, H. P., Reutelingsperger, C. P., Tervaert, J. W., & van Paassen, P. (2013). Immunoglobulin G anti-endothelial cell antibodies: inducers of endothelial cell apoptosis in pulmonary arterial hypertension?Clinical and Experimental Immunology, 174(3), 433-440. https://doi.org/10.1111/cei.12166

Kuster, D. W. D., Mulders, J., ten Cate, F. J., Michels, M., dos Remedios, C. G., Martins, P. A. D. C., van der Velden, J., & Oudejans, C. B. M. (2013). MicroRNA transcriptome profiling in cardiac tissue of hypertrophic cardiomyopathy patients with MYBPC3 mutations. Journal of Molecular and Cellular Cardiology, 65, 59-66. https://doi.org/10.1016/j.yjmcc.2013.09.012

Dirkx, E., da Costa Martins, P. A., & De Windt, L. J. (2013). Regulation of fetal gene expression in heart failure. Biochimica et Biophysica Acta-Molecular Basis of Disease, 1832(12), 2414-2424. https://doi.org/10.1016/j.bbadis.2013.07.023

Dirkx, E., Gladka, M. M., Philippen, L. E., Armand, A.-S., Kinet, V., Leptidis, S., el Azzouzi, H., Salic, K., Bourajjaj, M., da Silva, G. J. J., Olieslagers, S., van der Nagel, R., de Weger, R., Bitsch, N., Kisters, N., Seyen, S., Morikawa, Y., Chanoine, C., Heymans, S., ... De Windt, L. J. (2013). Nfat and miR-25 cooperate to reactivate the transcription factor Hand2 in heart failure. Nature Cell Biology, 15(11), 1282-1293. https://doi.org/10.1038/ncb2866

Maeder, M. T., Rickenbacher, P., Rickli, H., Abbuehl, H., Gutmann, M., Erne, P., Vuilliomenet, A., Peter, M., Pfisterer, M., & Brunner-La Rocca, H.-P. (2013). N-terminal pro brain natriuretic peptide-guided management in patients with heart failure and preserved ejection fraction: findings from the Trial of Intensified versus standard Medical therapy in Elderly patients with Congestive Heart Failure (TIME-CHF). European journal of heart failure, 15(10), 1148-1156. https://doi.org/10.1093/eurjhf/hft076

Ruijters, E. J. B., Weseler, A. R., Kicken, C., Haenen, G. R. M. M., & Bast, A. (2013). The flavanol (-)-epicatechin and its metabolites protect against oxidative stress in primary endothelial cells via a direct antioxidant effect.European Journal of Pharmacology, 715(1-3), 147-153. https://doi.org/10.1016/j.ejphar.2013.05.029

El Azzouzi, H., Leptidis, S., Dirkx, E., Hoeks, J., van Bree, B., van de Brand, K., McClellan, E. A., Poels, E., Sluimer, J. C., van den Hoogenhof, M. M., Armand, A. S., Yin, X., Langley, S., Bourajjaj, M., Olieslagers, S., Krishnan, J., Vooijs, M., Kurihara, H., Stubbs, A., ... De Windt, L. J. (2013). The Hypoxia-Inducible MicroRNA Cluster miR-199a similar to 214 Targets Myocardial PPAR delta and Impairs Mitochondrial Fatty Acid Oxidation. Cell Metabolism, 18(3), 341-354. https://doi.org/10.1016/j.cmet.2013.08.009

Caforio, A. L. P., Pankuweit, S., Arbustini, E., Basso, C., Gimeno-Blanes, J., Felix, S. B., Fu, M., Helio, T., Heymans, S., Jahns, R., Klingel, K., Linhart, A., Maisch, B., McKenna, W., Mogensen, J., Pinto, Y. M., Ristic, A., Schultheiss, H.-P., Seggewiss, H., ... Elliott, P. M. (2013). Current state of knowledge on aetiology, diagnosis, management, and therapy of myocarditis: a position statement of the European Society of Cardiology Working Group on Myocardial and Pericardial Diseases. European Heart Journal, 34(33), 2636-2648. https://doi.org/10.1093/eurheartj/eht210

van de Wier, B., Balk, J. M., Haenen, G. R. M. M., Giamouridis, D., Bakker, J. A., Bast, B. C., den Hartog, G. J. M., Koek, G. H., & Bast, A. (2013). Elevated citrate levels in non-alcoholic fatty liver disease: The potential of citrate to promote radical production. Febs Letters, 587(15), 2461-2466. https://doi.org/10.1016/j.febslet.2013.06.019