• 2016
    • Hermans, K. C. M., Daskalopoulos, E. P., & Blankesteijn, M. (2016). The Janus face of myofibroblasts in the remodeling heart. Journal of Molecular and Cellular Cardiology, 91, 35-41. https://doi.org/10.1016/j.yjmcc.2015.11.017
    • Uitterdijk, A., Hermans, K. C. M., de Wijs-Meijler, D. P. M., Daskalopoulos, E. P., Reiss, I. K., Duncker, D. J., Blankesteijn, M., & Merkus, D. (2016). UM206, a selective Frizzled antagonist, attenuates adverse remodeling after myocardial infarction in swine. Laboratory Investigation, 96(2), 168-176. https://doi.org/10.1038/labinvest.2015.139
    • Brunner-La Rocca, H., Fleischhacker, L., Golubnitschaja, O., Heemskerk, F., Helms, T., Hoedemakers, T., Allianses, S. H., Jaarsma, T., Kinkorova, J., Ramaekers, J., Ruff, P., Schnur, I., Vanoli, E., Verdu, J., & Zippel-Schultz, B. (2016). Challenges in personalised management of chronic diseases-heart failure as prominent example to advance the care process. The EPMA Journal, 7(1), Article 2. https://doi.org/10.1186/s13167-016-0051-9
    • Randall, M., Haenen, G. R., Bouwman, F. G., Vliet, A. V., & Bast, A. (2016). The tobacco smoke component acrolein induces glucocorticoid resistant gene expression via inhibition of histone deacetylase. Toxicology Letters, 240(1), 43-49. https://doi.org/10.1016/j.toxlet.2015.10.009
    • Daamen, M. A. M. J., Hamers, J. P. H., Gorgels, A. P. M., Tan, F. E. S., Schols, J. M. G. A., & Brunner-La Rocca, H. (2016). Treatment of heart failure in nursing home residents. Journal of Geriatric Cardiology, 13(1), 44-50. https://doi.org/10.11909/j.issn.1671-5411.2016.01.001
    • Van Aelst, L. N. L., Summer, G., Li, S., Gupta, S. K., Heggermont, W., De Vusser, K., Carai, P., Naesens, M., Van Cleemput, J., Van de Werf, F., Vanhaecke, J., Thum, T., Waer, M., Papageorgiou, A. .-P., Schroen, B., & Heymans, S. (2016). RNA Profiling in Human and Murine Transplanted Hearts: Identification and Validation of Therapeutic Targets for Acute Cardiac and Renal Allograft Rejection. American Journal of Transplantation, 16(1), 99-110. https://doi.org/10.1111/ajt.13421
    • van der Velden - Daamen, M., Hamers, J., Brunner-La Rocca, H., & Schols, J. (2016). Hartfalen bij verpleeghuisbewoners: Een moeilijke diagnose. Nederlands Tijdschrift voor Geneeskunde, 160, Article D390. https://www.ntvg.nl/system/files/publications/d390.pdf
    • Pijls, K., Jonkers, D., Elizalde Vilalta, M., Drittij - Reijnders, M. J., Haenen, G., Bast, A., Masclee, A., & Koek, G. (2016). Is intestinal oxidative stress involved in patients with compensated liver cirrhosis?Annals of Hepatology, 15(3), 402-409. https://doi.org/10.5604/16652681.1198816
    • Begieneman, M. P. V., Emmens, R. W., Rijvers, L., Kubat, B., Paulus, W. J., Vonk, A. B. A., Rozendaal, L., Biesbroek, P. S., Wouters, D., Zeerleder, S., van Ham, M., Heymans, S., van Rossum, A. C., Niessen, H. W. M., & Krijnen, P. A. J. (2016). Ventricular myocarditis coincides with atrial myocarditis in patients. Cardiovascular Pathology, 25(2), 141-148. https://doi.org/10.1016/j.carpath.2015.12.001
  • 2015
    • Daamen, M. A. M. J., Hamers, J. P. H., Gorgels, A. P. M., Brunner-La Rocca, H. P., Tan, F. E. S., van Dieijen-Visser, M. P., & Schols, J. M. G. A. (2015). Heart failure in nursing home residents; a cross-sectional study to determine the prevalence and clinical characteristics. BMC Geriatrics, 15(1), Article 167. https://doi.org/10.1186/s12877-015-0166-1
    • Zuurbier, C. J., Koeman, A., & Janssen, B. J. (2015). Letter to the editor: Ketamine-only versus isoflurane effects on murine cardiac function: comparison at similar depths of anesthesia?American Journal of Physiology-heart and Circulatory Physiology, 309(12), H2160. https://doi.org/10.1152/ajpheart.00792.2015
    • van de Wier, B., Balk, J. M., Bast, A., Koek, G. H., & Haenen, G. R. (2015). Chemical characteristics for optimizing CYP2E1 inhibition. Chemico-Biological Interactions, 242, 139-144. https://doi.org/10.1016/j.cbi.2015.09.024
    • Summer, G., Kelder, T., Ono, K., Radonjic, M., Heymans, S., & Demchak, B. (2015). cyNeo4j: connecting Neo4j and Cytoscape. Bioinformatics, 31(23), 3868-3869. https://doi.org/10.1093/bioinformatics/btv460
    • Vrolijk, M. F., Opperhuizen, A., Jansen, E. H., Bast, A., & Haenen, G. R. (2015). Anticholinergic Accumulation: A Slumbering Interaction between Drugs and Food Supplements. Basic & Clinical Pharmacology & Toxicology, 117(6), 427-432. https://doi.org/10.1111/bcpt.12437
    • Philippen, L. E., Dirkx, E., Wit, J. B. M., Burggraaf, K., de Windt, L. J., & Martins, P. A. D. C. (2015). Antisense MicroRNA Therapeutics in Cardiovascular Disease: Quo Vadis?Molecular Therapy, 23(12), 1810-1818. https://doi.org/10.1038/mt.2015.133
    • Ounzain, S., Micheletti, R., Arnan, C., Plaisance, I., Cecchi, D., Schroen, B., Reverter, F., Alexanian, M., Gonzales, C., Ng, S. Y., Bussotti, G., Pezzuto, I., Notredame, C., Heymans, S., Guigo, R., Johnson, R., & Pedrazzini, T. (2015). CARMEN, a human super enhancer-associated long noncoding RNA controlling cardiac specification, differentiation and homeostasis. Journal of Molecular and Cellular Cardiology, 89, 98-112. https://doi.org/10.1016/j.yjmcc.2015.09.016
    • Calore, M., De Windt, L. J., & Rampazzo, A. (2015). Genetics meets epigenetics: Genetic variants that modulate noncoding RNA in cardiovascular diseases. Journal of Molecular and Cellular Cardiology, 89, 27-34. https://doi.org/10.1016/j.yjmcc.2015.10.028
    • Philippen, L. E., Dirkx, E., da Costa-Martins, P. A., & De Windt, L. J. (2015). Non-coding RNA in control of gene regulatory programs in cardiac development and disease. Journal of Molecular and Cellular Cardiology, 89(Pt A), 51-8. https://doi.org/10.1016/j.yjmcc.2015.03.014
    • De Windt, L. J., & Thum, T. (2015). State-of-the-art on non-coding RNA bioinformatics, diagnostics and therapeutics in cardiovascular diseases: Preface to SI Non-coding RNAs in cardiovascular disease. Journal of Molecular and Cellular Cardiology, 89(Pt A), 1-2. https://doi.org/10.1016/j.yjmcc.2015.11.021
    • Brunner-La Rocca, H.-P., Eurlings, L., Richards, A. M., Januzzi, J. L., Pfisterer, M. E., Dahlstrom, U., Pinto, Y. M., Karlstrom, P., Erntell, H., Berger, R., Persson, H., O'Connor, C. M., Moertl, D., Gaggin, H. K., Frampton, C. M., Nicholls, M. G., & Troughton, R. W. (2015). Which heart failure patients profit from natriuretic peptide guided therapy? A meta-analysis from individual patient data of randomized trials. European journal of heart failure, 17(12), 1252-1261. https://doi.org/10.1002/ejhf.401
    • Rezk, B. M., van der Vijgh, W., Bast, A., & Haenen, G. (2015). Toxicity of Antioxidants. Toxicology and Forensic Medicine, 1(1), e3-e4. Article 1000TFMOJ1e002. https://doi.org/10.17140/TFMOJ-1-e002
    • Hazebroek, M. R., Kemna, M. J., Schalla, S., Sanders-van Wijk, S., Gerretsen, S. C., Dennert, R., Merken, J., Kuznetsova, T., Staessen, J. A., Brunner-La Rocca, H. P., van Paassen, P., Tervaert, J. W. C., & Heymans, S. (2015). Prevalence and prognostic relevance of cardiac involvement in ANCA-associated vasculitis: Eosinophilic granulomatosis with polyangiitis and granulomatosis with polyangiitis. International Journal of Cardiology, 199, 170-179. https://doi.org/10.1016/j.ijcard.2015.06.087
    • Corsten, M., Heggermont, W., Papageorgiou, A.-P., Deckx, S., Tijsma, A., Verhesen, W., van Leeuwen, R., Carai, P., Thibaut, H.-J., Custers, K., Summer, G., Hazebroek, M., Verheyen, F., Neyts, J., Schroen, B., & Heymans, S. (2015). The microRNA-221/-222 cluster balances the antiviral and inflammatory response in viral myocarditis. European Heart Journal, 36(42), 2909-U56. https://doi.org/10.1093/eurheartj/ehv321
    • Calore, M., & De Windt, L. J. (2015). Longing for Naiades in Heart Failure. Journal of the American College of Cardiology, 66(18), 2016-2018. https://doi.org/10.1016/j.jacc.2015.08.868
    • Grootaert, M. O. J., Martins, P. A. D. C., Bitsch, N., Pintelon, I., De Meyer, G. R. Y., Martinet, W., & Schrijvers, D. M. (2015). Defective autophagy in vascular smooth muscle cells accelerates senescence and promotes neointima formation and atherogenesis. Autophagy, 11(11), 2014-2032. https://doi.org/10.1080/15548627.2015.1096485
    • Blankesteijn, W. M. (2015). Has the search for a marker of activated fibroblasts finally come to an end?Journal of Molecular and Cellular Cardiology, 88, 120-123. https://doi.org/10.1016/j.yjmcc.2015.10.005
    • Daeichin, V., Sluimer, J. C., van der Heiden, K., Skachkov, I., Kooiman, K., Janssen, A., Janssen, B., Bosch, J. G., de Jong, N., Daemen, M. J. A. P., & van der Steen, A. F. W. (2015). Live Observation of Atherosclerotic Plaque Disruption in Apolipoprotein E-Deficient Mouse. Ultrasound International Open, 1(2), E67-71. https://doi.org/10.1055/s-0035-1565092
    • Altara, R., Gu, Y.-M., Struijker-Boudier, H. A. J., Thijs, L., Staessen, J. A., & Blankesteijn, W. M. (2015). Left Ventricular Dysfunction and CXCR3 Ligands in Hypertension: From Animal Experiments to a Population-Based Pilot Study. PLOS ONE, 10(10), Article e0141394. https://doi.org/10.1371/journal.pone.0141394
    • Lok, S. I., de Jonge, N., van Kuik, J., van Geffen, A. J. P., Huibers, M. M. H., van der Weide, P., Siera, E., Winkens, B., Doevendans, P. A., de Weger, R. A., & Da Costa Martins, P. A. (2015). MicroRNA Expression in Myocardial Tissue and Plasma of Patients with End-Stage Heart Failure during LVAD Support: Comparison of Continuous and Pulsatile Devices. PLOS ONE, 10(10), Article e0136404. https://doi.org/10.1371/journal.pone.0136404
    • d'Avenia, M., Citro, R., De Marco, M., Veronese, A., Rosati, A., Visone, R., Leptidis, S., Philippen, L., Vitale, G., Cavallo, A., Silverio, A., Prota, C., Gravina, P., De Cola, A., Carletti, E., Coppola, G., Gallo, S., Provenza, G., Bossone, E., ... De laurenzi, V. (2015). A novel miR-371a-5p-mediated pathway, leading to BAG3 upregulation in cardiomyocytes in response to epinephrine, is lost in Takotsubo cardiomyopathy. Cell Death & Disease, 6(10), Article e1948. https://doi.org/10.1038/cddis.2015.280
    • Kosanovic, D., Luitel, H., Dahal, B. K., Cornitescu, T., Janssen, W., Danser, A. H. J., Garrelds, I. M., De Mey, J. G. R., Fazzi, G., Schiffers, P., Iglarz, M., Fischli, W., Ghofrani, H. A., Weissmann, N., Grimminger, F., Seeger, W., Reiss, I., & Schermuly, R. T. (2015). Chymase: a multifunctional player in pulmonary hypertension associated with lung fibrosis. European Respiratory Journal, 46(4), 1084-1094. https://doi.org/10.1183/09031936.00018215
    • Salden, B. N., Montserrat, V., Troost, F. J., Bruins, M. J., Edens, L., Bartholomé, R., Haenen, G. R., Winkens, B., Koning, F., & Masclee, A. A. (2015). Letter: gluten digestion in the stomach and duodenum by Aspergillus niger-derived enzyme - things to ponder. Authors' reply. Alimentary Pharmacology & Therapeutics, 42(7), 946-947. https://doi.org/10.1111/apt.13382
    • Piers, S. R. D., Everaerts, K., van der Geest, R. J., Hazebroek, M. R., Siebelink, H.-M., Pison, L. A. F. G., Schalij, M. J., Bekkers, S. C. A. M., Heymans, S., & Zeppenfeld, K. (2015). Myocardial scar predicts monomorphic ventricular tachycardia but not polymorphic ventricular tachycardia or ventricular fibrillation in nonischemic dilated cardiomyopathy. Heart Rhythm, 12(10), 2106-2114. https://doi.org/10.1016/j.hrthm.2015.05.026
    • Knackstedt, C., Bekkers, S. C. A. M., Schummers, G., Schreckenberg, M., Muraru, D., Badano, L. P., Franke, A., Bavishi, C., Omar, A. M. S., & Sengupta, P. P. (2015). Fully Automated Versus Standard Tracking of Left Ventricular Ejection Fraction and Longitudinal Strain The FAST-EFs Multicenter Study. Journal of the American College of Cardiology, 66(13), 1456-1466. https://doi.org/10.1016/j.jacc.2015.07.052
    • Deckx, S., Carai, P., Bateman, J., Heymans, S., & Papageorgiou, A.-P. (2015). Breeding Strategy Determines Rupture Incidence in Post-Infarct Healing WARPing Cardiovascular Research. PLOS ONE, 10(9), Article e0139199. https://doi.org/10.1371/journal.pone.0139199
    • Hazebroek, M. R., Moors, S., Dennert, R., van den Wijngaard, A., Krapels, I., Hoos, M., Verdonschot, J., Merken, J. J., de Vries, B., Wolffs, P. F., Crijns, H. J. G. M., Brunner-La Rocca, H. P., & Heymans, S. (2015). Prognostic Relevance of Gene-Environment Interactions in Patients With Dilated Cardiomyopathy: Applying the MOGE(S) Classification. Journal of the American College of Cardiology, 66(12), 1313-1323. https://doi.org/10.1016/j.jacc.2015.07.023
    • Blankesteijn, W. M., & Hermans, K. C. M. (2015). Wnt signaling in atherosclerosis. European Journal of Pharmacology, 763, 122-130. https://doi.org/10.1016/j.ejphar.2015.05.023
    • Bartholomé, R., Salden, B., Vrolijk, M. F., Troost, F. J., Masclee, A., Bast, A., & Haenen, G. R. M. M. (2015). Paracetamol as a Post Prandial Marker for Gastric Emptying, A Food-Drug Interaction on Absorption. PLOS ONE, 10(9), Article e0136618. https://doi.org/10.1371/journal.pone.0136618
    • Lemmens, K. J., Herst, P. M., Housmans, B. A., Moalin, M., van der Vijgh, W. J., Bast, A., & Haenen, G. R. (2015). The contribution of the major metabolite 4'-O-methylmonoHER to the antioxidant activity of the flavonoid monoHER. Chemico-Biological Interactions, 239, 146-152. https://doi.org/10.1016/j.cbi.2015.07.004
    • Benedikter, B. J., Volgers, C., Haenen, G. R. M. M., Savelkoul, P. H. M., Wouters, E. F. M., Rohde, G. G. U., Weseler, A. R., & Stassen, F. R. M. (2015). Cigarette smoke extract induces the release of extracellular vesicles by airway epithelial cells via cellular carbonyl stress. European Respiratory Journal, 46(suppl 59). https://doi.org/10.1183/13993003.congress-2015.PA5113
    • Knackstedt, C., Hildebrandt, U., Schmidt, K., Syrocki, L., Lang, A., Bjarnason-Wehrens, B., Schummers, G., Stapf, D., Becker, M., & Predel, H. G. (2015). Analysis of right and left ventricular deformation in former world class swimmers: evaluation using speckle tracking. Journal of Sports Medicine and Physical Fitness, 55(9), 978-987.
    • Cannon, M. V., Sillje, H. H. W., Sijbesma, J. W. A., Vreeswijk-Baudoin, I., Ciapaite, J., van der Sluis, B., van Deursen, J., Silva, G. J. J., de Windt, L. J., Gustafsson, J.-A., van der Harst, P., van Gilst, W. H., & de Boer, R. A. (2015). Cardiac LXR protects against pathological cardiac hypertrophy and dysfunction by enhancing glucose uptake and utilization. EMBO Molecular Medicine, 7(9), 1229-1243. https://doi.org/10.15252/emmm.201404669
    • el Azzouzi, H., Leptidis, S., Doevendans, P. A., & De Windt, L. J. (2015). HypoxamiRs: regulators of cardiac hypoxia and energy metabolism. Trends in Endocrinology and Metabolism, 26(9), 502-508. https://doi.org/10.1016/j.tem.2015.06.008
    • Salden, B. N., Monserrat, V., Troost, F. J., Bruins, M. J., Edens, L., Bartholomé, R., Haenen, G. R., Winkens, B., Koning, F., & Masclee, A. A. (2015). Editorial: enhancing gluten digestion in the stomach- a further help to minimise unintentional ingestion? Authors' reply. Alimentary Pharmacology & Therapeutics, 42(4), 485. https://doi.org/10.1111/apt.13296
    • Heymans, S., Gonzalez, A., Pizard, A., Papageorgiou, A. P., Lopez-Andres, N., Jaisser, F., Thum, T., Zannad, F., & Diez, J. (2015). Searching for new mechanisms of myocardial fibrosis with diagnostic and/or therapeutic potential. European journal of heart failure, 17(8), 764-771. https://doi.org/10.1002/ejhf.312
    • Kaufmann, B. A., Goetschalckx, K., Min, S. Y., Maeder, M. T., Bucher, U., Nietlispach, F., Bernheim, A. M., Pfisterer, M. E., Brunner-La Rocca, H. P., & TIME-CHF Investigators, T. (2015). Improvement in left ventricular ejection fraction and reverse remodeling in elderly heart failure patients on intense NT-proBNP-guided therapy. International Journal of Cardiology, 191, 286-293. https://doi.org/10.1016/j.ijcard.2015.04.282
    • Papageorgiou, A.-P., Heggermont, W., Rienks, M., Carai, P., Langouche, L., Verhesen, W., De Boer, R. A., & Heymans, S. (2015). Liver X receptor activation enhances CVB3 viral replication during myocarditis by stimulating lipogenesis. Cardiovascular Research, 107(1), 78-88. https://doi.org/10.1093/cvr/cvv157
    • Tchaikovski, V., Tchaikovski, S., Olieslagers, S., & Waltenberger, J. (2015). Monocyte dysfunction as a previously unrecognized pathophysiological mechanism in ApoE-/- mice contributing to impaired arteriogenesis. International Journal of Cardiology, 190(1), 214-216. https://doi.org/10.1016/j.ijcard.2015.04.188
    • Devaux, Y., Zangrando, J., Schroen, B., Creemers, E. E., Pedrazzini, T., Chang, C.-P., Dorn, G. W. . II., Thum, T., & Heymans, S. (2015). Long noncoding RNAs in cardiac development and ageing. Nature Reviews Cardiology, 12(7), 415-425. https://doi.org/10.1038/nrcardio.2015.55