Witjas-Paalberends, E. R., Piroddi, N., Stam, K., van Dijk, S. J., Oliviera, V. S., Ferrara, C., Scellini, B., Hazebroek, M., ten Cate, F. J., van Slegtenhorst, M., dos Remedios, C., Niessen, H. W. M., Tesi, C., Stienen, G. J. M., Heymans, S., Michels, M., Poggesi, C., & van der Velden, J. (2013). Mutations in MYH7 reduce the force generating capacity of sarcomeres in human familial hypertrophic cardiomyopathy. Cardiovascular Research, 99(3), 432-441. https://doi.org/10.1093/cvr/cvt119

Van Aelst, L. N. L., & Heymans, S. (2013). MicroRNAs as Biomarkers for Ischemic Heart Disease. Journal of Cardiovascular Translational Research, 6(4), 458-470. https://doi.org/10.1007/s12265-013-9466-z

Brouwers, O., de Vos-Houben, J. M., Niessen, P. M., Miyata, T., van Nieuwenhoven, F., Janssen, B. J., Hageman, G., Stehouwer, C. D., & Schalkwijk, C. G. (2013). Mild oxidative damage in the diabetic rat heart is attenuated by glyoxalase-1 overexpression. International Journal of Molecular Sciences, 14(8), 15724-15739. https://doi.org/10.3390/ijms140815724

Sanders-van Wijk, S., Muzzarelli, S., Neuhaus, M., Kiencke, S., Maeder, M., Estlinbaum, W., Tobler, D., Mayer, K., Erne, P., Pfisterer, M. E., & Brunner-La Rocca, H.-P. (2013). Safety and tolerability of intensified, N-terminal pro brain natriuretic peptide-guided compared with standard medical therapy in elderly patients with congestive heart failure: results from TIME-CHF. European journal of heart failure, 15(8), 910-918. https://doi.org/10.1093/eurjhf/hft079

Vanhoutte, D., van Almen, G. C., Van Aelst, L. N. L., Van Cleemput, J., Droogne, W., Jin, Y., Van de Werf, F., Carmeliet, P., Vanhaecke, J., Papageorgiou, A.-P., & Heymans, S. (2013). Matricellular proteins and matrix metalloproteinases mark the inflammatory and fibrotic response in human cardiac allograft rejection. European Heart Journal, 34(25), 1930-1941. https://doi.org/10.1093/eurheartj/ehs375

Lok, S. I., van Mil, A., Bovenschen, N., van der Weide, P., van Kuik, J., van Wichen, D., Peeters, T., Siera, E., Winkens, B., Sluijter, J. P. G., Doevendans, P. A., Martins, P. A. D. C., de Jonge, N., & de Weger, R. A. (2013). Post-transcriptional Regulation of a-1-Antichymotrypsin by MicroRNA-137 in Chronic Heart Failure and Mechanical Support. Circulation-Heart Failure, 6(4), 853-861. https://doi.org/10.1161/CIRCHEARTFAILURE.112.000255

Tritsch, E., Mallat, Y., Lefebvre, F., Diguet, N., Escoubet, B., Blanc, J., De Windt, L. J., Catalucci, D., Vandecasteele, G., Li, Z., & Mericskay, M. (2013). An SRF/miR-1 axis regulates NCX1 and Annexin A5 protein levels in the normal and failing heart. Cardiovascular Research, 98(3), 372-380. https://doi.org/10.1093/cvr/cvt042

Res, P. T., Cermak, N. M., Stinkens, R. E., Tollakson, T. J., Haenen, G. R. M. M., Bast, A., & van Loon, L. J. C. (2013). Astaxanthin supplementation does not augment fat use or improve endurance performance.Medicine and Science in Sports and Exercise, 45(6), 1158-1165. https://doi.org/10.1249/MSS.0b013e31827fddc4

Huijts, M., van Oostenbrugge, R. J., Duits, A., Burkard, T., Muzzarelli, S., Maeder, M. T., Schindler, R., Pfisterer, M. E., & Brunner-La Rocca, H.-P. (2013). Cognitive impairment in heart failure: results from the Trial of Intensified versus standard Medical therapy in Elderly patients with Congestive Heart Failure (TIME-CHF) randomized trial. European journal of heart failure, 15(6), 699-707. https://doi.org/10.1093/eurjhf/hft020

VanTeeffelen, J. W. G. E., Brands, J., Janssen, B. J. A., & Vink, H. (2013). Effect of acute hyaluronidase treatment of the glycocalyx on tracer-based whole body vascular volume estimates in mice. Journal of Applied Physiology, 114(9), 1132-1140. https://doi.org/10.1152/japplphysiol.00842.2012

Daskalopoulos, E. P., Hermans, K. C. M., Janssen, B. J. A., & Blankesteijn, W. M. (2013). Targeting the Wnt/frizzled signaling pathway after myocardial infarction: A new tool in the therapeutic toolbox?Trends in Cardiovascular Medicine, 23(4), 121-127. https://doi.org/10.1016/j.tcm.2012.09.010

Stapf, D., Franke, A., Schreckenberg, M., Schummers, G., Mischke, K., Marx, N., Schauerte, P., & Knackstedt, C. (2013). Beat to beat 3-dimensional intracardiac echocardiography: theoretical approach and practical experiences. International Journal of Cardiovascular Imaging, 29(4), 753-764. https://doi.org/10.1007/s10554-012-0136-z

Mischke, K., Knackstedt, C., Marx, N., & Vollmann, D. (2013). Insights into atrial fibrillation. Minerva Medica, 104(2), 119-130.

Vanhees, K., van Schooten, F. J., van Waalwijk van Doorn-Khosrovani, S. B., van Helden, S. H., Munnia, A., Peluso, M., Briedé, J. J., Haenen, G. R. M. M., & Godschalk, R. W. L. (2013). Intrauterine exposure to flavonoids modifies antioxidant status at adulthood and decreases oxidative stress-induced DNA damage. Free Radical Biology and Medicine, 57, 154-161. https://doi.org/10.1016/j.freeradbiomed.2012.12.021

Camporeale, A., Marino, F., Papageorgiou, A., Carai, P., Fornero, S., Fletcher, S., Page, B. D. G., Gunning, P., Forni, M., Chiarle, R., Morello, M., Jensen, O., Levi, R., Heymans, S., & Poli, V. (2013). STAT3 activity is necessary and sufficient for the development of immune-mediated myocarditis in mice and promotes progression to dilated cardiomyopathy. EMBO Molecular Medicine, 5(4), 572-590. https://doi.org/10.1002/emmm.201201876

Aleksinskaya, M. A., van Faassen, E. E. H., Nelissen, J., Janssen, B. J. A., De Mey, J. G. R., Hanemaaijer, R., Rabelink, T., & van Zonneveld, A. J. (2013). Identification of Free Nitric Oxide Radicals in Rat Bone Marrow: Implications for Progenitor Cell Mobilization in Hypertension. PLOS ONE, 8(3), Article e57761. https://doi.org/10.1371/journal.pone.0057761

Kaufmann, B. A., Min, S. Y., Goetschalckx, K., Bernheim, A. M., Buser, P. T., Pfisterer, M. E., & Brunner-La Rocca, H.-P. (2013). How reliable are left ventricular ejection fraction cut offs assessed by echocardiography for clinical decision making in patients with heart failure?International Journal of Cardiovascular Imaging, 29(3), 581-588. https://doi.org/10.1007/s10554-012-0122-5

Heijnen, B. F. J., Nelissen, J., van Essen, H., Fazzi, G. E., Tervaert, J. W. C., Peutz-Kootstra, C. J., Mullins, J. J., Schalkwijk, C. G., Janssen, B. J. A., & Struijker-Boudier, H. A. J. (2013). Irreversible Renal Damage after Transient Renin-Angiotensin System Stimulation: Involvement of an AT(1)-Receptor Mediated Immune Response. PLOS ONE, 8(2), Article e57815. https://doi.org/10.1371/journal.pone.0057815

Leptidis, S., el Azzouzi, H., Lok, S. I., de Weger, R., Olieslagers, S., Kisters, N., Silva, G. J., Heymans, S., Cuppen, E., Berezikov, E., De Windt, L. J., & Martins, P. D. C. (2013). A Deep Sequencing Approach to Uncover the miRNOME in the Human Heart. PLOS ONE, 8(2), Article e57800. https://doi.org/10.1371/journal.pone.0057800

Borissoff, J. I., Otten, J. J. T., Heeneman, S., Leenders, P., van Oerle, R., Soehnlein, O., Loubele, S. T. B. G., Hamulyak, K., Hackeng, T. M., Daemen, M. J. A. P., Degen, J. L., Weiler, H., Esmon, C. T., van Ryn, J., Biessen, E. A. L., Spronk, H. M. H., & ten Cate, H. (2013). Genetic and Pharmacological Modifications of Thrombin Formation in Apolipoprotein E-deficient Mice Determine Atherosclerosis Severity and Atherothrombosis Onset in a Neutrophil-Dependent Manner. PLOS ONE, 8(2), Article e55784. https://doi.org/10.1371/journal.pone.0055784

Nergiz-Unal, R., Kuijpers, M. J. E., de Witt, S. M., Heeneman, S., Feijge, M. A. H., Garcia Caraballo, S., Biessen, E. A., Haenen, G. R. M. M., Cosemans, J. M., & Heemskerk, J. W. (2013). Atheroprotective effect of dietary walnut intake in ApoE-deficient mice: Involvement of lipids and coagulation factors.Thrombosis Research, 131(5), 411-417. https://doi.org/10.1016/j.thromres.2013.01.003

Klinkenberg, L. J., Res, P. T., Haenen, G. R., Bast, A., van Loon, L. J., van Dieijen-Visser, M. P., & Meex, S. J. (2013). Effect of antioxidant supplementation on exercise-induced cardiac troponin release in cyclists: a randomized trial. PLOS ONE, 8(11), Article e79280. https://doi.org/10.1371/journal.pone.0079280

Arends, S. J., Damoiseaux, J. G., Duijvestijn, A. M., Debrus-Palmans, L., Boomars, K. A., Brunner-La Rocca, H. P., Tervaert, J. W., & van Paassen, P. (2013). Functional implications of IgG anti-endothelial cell antibodies in pulmonary arterial hypertension. Autoimmunity, 46(7), 463-470. https://doi.org/10.3109/08916934.2013.812080

Bast, A., & Haenen, G. R. M. M. (2013). Ten misconceptions about antioxidants. Trends in Pharmacological Sciences, 34(8), 430-436. https://doi.org/10.1016/j.tips.2013.05.010

Smulders, M. W., Kietselaer, B. L. J. H., Das, M., Wildberger, J. E., Crijns, H. J. G. M., Veenstra, L., Brunner La Rocca, H. P., van Dieijen-Visser, M. P., Mingels, A. M. A., Dagnelie, P. C., Post, M. J., Gorgels, A. P. M., van Asselt, A. D. I., Vogel, G., Schalla, S., Kim, R. J., & Bekkers, S. C. A. M. (2013). The role of cardiovascular magnetic resonance imaging and computed tomography angiography in suspected non-ST-elevation myocardial infarction patients: Design and rationale of the CARdiovascular Magnetic rEsoNance imaging and computed Tomography Angiography (CARMENTA) trial. American Heart Journal, 166(6), 968-975. https://doi.org/10.1016/j.ahj.2013.09.012

Jeger, R. V., Rocca, H. P. B.-L., Bertel, O., Kiowski, W., Pfisterer, M. E., & Kaiser, C. A. (2013). Stent Thrombosis after Coronary Stent Implantation: A Protective Effect of High-Dose Statin Therapy?Cardiology, 126(2), 115-121. https://doi.org/10.1159/000350822

van Empel, V. P. M., De Windt, L. J., & Martins, P. A. D. C. (2012). Circulating miRNAs: Reflecting or Affecting Cardiovascular Disease?Current Hypertension Reports, 14(6), 498-509. https://doi.org/10.1007/s11906-012-0310-7

Scharf, C., Ng, G. A., Wieczorek, M., Deneke, T., Furniss, S. S., Murray, S., Debruyne, P., Hobson, N., Berntsen, R. F., Schneider, M. A., Hauer, H. A., Halimi, F., Boveda, S., Asbach, S., Boesche, L., Zimmermann, M., Brigadeau, F., Taieb, J., Merkel, M., ... Boersma, L. V. A. (2012). European survey on efficacy and safety of duty-cycled radiofrequency ablation for atrial fibrillation. EP Europace, 14(12), 1700-1707. https://doi.org/10.1093/europace/eus188

Spruit, M. A., Maeder, M. T., Knackstedt, C., Ammann, P., Jeker, U., Uszko-Lencer, N., Kiencke, S., Pfisterer, M. E., Rickli, H., & Brunner La Rocca, H. P. (2012). Prognostic Value of Self-Reported Versus Objectively Measured Functional Capacity in Patients With Heart Failure Results From the TIME-CHF (Trial of Intensified Versus Standard Medical Therapy in Elderly Patients With Congestive Heart Failure). Journal of the American College of Cardiology, 60(20), 2125-2126. https://doi.org/10.1016/j.jacc.2012.08.968

Lemkens, P., Nelissen, J., Meens, M. J. P. M. T., Fazzi, G. E., Janssen, G. J. M., Debets, J. J. M., Janssen, B. J. A., Schiffers, P. M. H., & De Mey, J. G. R. (2012). Impaired flow-induced arterial remodeling in DOCA-salt hypertensive rats. Hypertension Research, 35(11), 1093-1101. https://doi.org/10.1038/hr.2012.94

Heggermont, W. A., & Heymans, S. (2012). MicroRNAs Are Involved in End-Organ Damage During Hypertension. Hypertension, 60(5), 1088-1093. https://doi.org/10.1161/HYPERTENSIONAHA.111.187104

Bourgonje, V. J. A., Schoenmakers, M., Beekman, J. D. M., van der Nagel, R., Houtman, M. J. C., Miedema, L. F., Antoons, G., Sipido, K., de Windt, L. J., van Veen, T. A. B., & Vos, M. A. (2012). Relevance of calmodulin/CaMKII activation for arrhythmogenesis in the AV block dog. Heart Rhythm, 9(11), 1875-1883.e2. https://doi.org/10.1016/j.hrthm.2012.07.023

Rickenbacher, P., Pfisterer, M., Burkard, T., Kiowski, W., Follath, F., Burckhardt, D., Schindler, R., & Rocca, H.-P. B.-L. (2012). Why and how do elderly patients with heart failure die? Insights from the TIME-CHF study. European journal of heart failure, 14(11), 1218-1229. https://doi.org/10.1093/eurjhf/hfs113

Eurlings, L. W., van Wijk, S., van Kimmenade, R., Osinski, A., van Helmond, L., Vallinga, M., Crijns, H. J., van Dieijen-Visser, M. P., Brunner La Rocca, H. P., & Pinto, Y. M. (2012). Multimarker strategy for short-term risk assessment in patients with dyspnea in the emergency department: The marked (multi marker emergency dyspnea)-risk score. Journal of the American College of Cardiology, 60(17), 1668-1677. https://doi.org/10.1016/j.jacc.2012.06.040

Nelissen, J., Lemkens, P., Sann, H., Bindl, M., Bassissi, F., Jasserand, D., De Mey, J. G. R., & Janssen, B. J. A. (2012). Pharmacokinetic and pharmacodynamic properties of SOL1: A novel dual inhibitor of neutral endopeptidase and endothelin converting enzyme. Life Sciences, 91(13-14), 587-592. https://doi.org/10.1016/j.lfs.2012.01.015

Lemkens, P., Nelissen, J., Meens, M. J. P. M. T., Janssen, B. J. A., Schiffers, P. M. H., & De Mey, J. G. R. (2012). Dual neural peptidase/endothelin-converting enzyme inhibition improves endothelial function in mesenteric resistance arteries of young spontaneously hypertensive rats. Journal of Hypertension, 30(9), 1799-1808. https://doi.org/10.1097/HJH.0b013e3283569c7a

Totzeck, M., Hendgen-Cotta, U. B., Rammos, C., Frommke, L.-M., Knackstedt, C., Predel, H.-G., Kelm, M., & Rassaf, T. (2012). Higher endogenous nitrite levels are associated with superior exercise capacity in highly trained athletes. Nitric Oxide-Biology and Chemistry, 27(2), 75-81. https://doi.org/10.1016/j.niox.2012.05.003

Knackstedt, C., Becker, M., Mischke, K., Pauling, R., Rocca, H. P. B.-L., & Schauerte, P. (2012). A dedicated cardioversion unit for the treatment of atrial fibrillation. Reducing costs by optimizing processes. Herz, 37(5), 518-526. https://doi.org/10.1007/s00059-011-3546-0

Dennert, R., van Paassen, P., Wolffs, P., Bruggeman, C., Velthuis, S., Felix, S., van Suylen, R.-J., Crijns, H. J., Tervaert, J. W. C., & Heymans, S. (2012). Differences in Virus Prevalence and Load in the Hearts of Patients with Idiopathic Dilated Cardiomyopathy with and without Immune-Mediated Inflammatory Diseases. Clinical and Vaccine Immunology, 19(8), 1182-1187. https://doi.org/10.1128/CVI.00281-12

Hazebroek, M., Dennert, R., & Heymans, S. (2012). Idiopathic dilated cardiomyopathy: possible triggers and treatment strategies. Netherlands Heart Journal, 20(7-8), 332-335. https://doi.org/10.1007/s12471-012-0285-7

Timmers, S., Nabben, M., Bosma, M., van Bree, B., Lenaers, E., Van Beurden, D., Schaart, G., Westerterp-Plantenga, M. S., Langhans, W., Hesselink, M. K. C., Schrauwen-Hinderling, V. B., & Schrauwen, P. (2012). Augmenting muscle diacylglycerol and triacylglycerol content by blocking fatty acid oxidation does not impede insulin sensitivity. Proceedings of the National Academy of Sciences of the United States of America, 109(29), 11711-11716. https://doi.org/10.1073/pnas.1206868109

Corsten, M. F., Schroen, B., & Heymans, S. (2012). Inflammation in viral myocarditis: friend or foe?Trends in Molecular Medicine, 18(7), 426-437. https://doi.org/10.1016/j.molmed.2012.05.005

Boots, A. W., Gerloff, K., Bartholomé, R., van Berlo, D., Ledermann, K., Haenen, G. R. M. M., Bast, A., van Schooten, F. J., Albrecht, C., & Schins, R. P. (2012). Neutrophils augment LPS-mediated pro-inflammatory signaling in human lung epithelial cells. Biochimica et Biophysica Acta-Molecular Cell Research, 1823(7), 1151-1162. https://doi.org/10.1016/j.bbamcr.2012.04.012

Altenhofer, S., Kleikers, P. W. M., Radermacher, K. A., Scheurer, P., Hermans, J. J. R., Schiffers, P., Ho, H., Wingler, K., & Schmidt, H. H. H. W. (2012). The NOX toolbox: validating the role of NADPH oxidases in physiology and disease. Cellular and Molecular Life Sciences, 69(14), 2327-2343. https://doi.org/10.1007/s00018-012-1010-9

el Azzouzi, H., Leptidis, S., Bourajjaj, M., van Bilsen, M., Martins, P. A. D. C., & De Windt, L. J. (2012). MEK1 Inhibits Cardiac PPAR alpha Activity by Direct Interaction and Prevents Its Nuclear Localization. PLOS ONE, 7(6), Article e36799. https://doi.org/10.1371/journal.pone.0036799

Daamen, M. A. M. J., Hamers, J. P. H., Gorgels, A. P. M., Brunner-La Rocca, H. P., Tan, F. E. S., van Dieijen-Visser, M. P., & Schols, J. M. G. A. (2012). The prevalence and management of heart failure in Dutch nursing homes: design of a multi-centre cross-sectional study. BMC Geriatrics, 12, Article 29. https://doi.org/10.1186/1471-2318-12-29

Salic, K., & De Windt, L. J. (2012). MicroRNAs as Biomarkers for Myocardial Infarction. Current Atherosclerosis Reports, 14(3), 193-200. https://doi.org/10.1007/s11883-012-0238-z