• 2012
    • Fransen, G. A. J., Mesters, I., Muris, J. W. M., Van Marrewijk, C. J., Mujakovic, S., Laheij, R. J. F., Numans, M. E., De Wit, N. J., Samsom, M., Jansen, J. B. M. J., & Knottnerus, J. A. (2012). Patient adherence to prescribed medication instructions for dyspepsia: The DIAMOND-study. European Journal of General Practice, 18(2), 79-85. https://doi.org/10.3109/13814788.2012.665443
    • Tivig, C., Dang, L., Brunner-La Rocca, H.-P., Oezcan, S., Duru, F., & Scharf, C. (2012). Duty-cycled unipolar/bipolar versus conventional radiofrequency ablation in paroxysmal and persistent atrial fibrillation. International Journal of Cardiology, 157(2), 185-191. https://doi.org/10.1016/j.ijcard.2010.12.010
    • Hazewindus, M., Haenen, G. R. M. M., Weseler, A. R., & Bast, A. (2012). The anti-inflammatory effect of lycopene complements the antioxidant action of ascorbic acid and alpha-tocopherol. Food Chemistry, 132(2), 954-958. https://doi.org/10.1016/j.foodchem.2011.11.075
    • Papageorgiou, A.-P., & Heymans, S. (2012). Interactions between the extracellular matrix and inflammation during viral myocarditis. Immunobiology, 217(5), 503-510. https://doi.org/10.1016/j.imbio.2011.07.011
    • Seemann, I., Gabriels, K., Visser, N. L., Hoving, S., te Poele, J. A., Pol, J. F., Gijbels, M. J., Janssen, B. J., Van Leeuwen, F. W., Daemen, M. J., Heeneman, S., & Stewart, F. A. (2012). Irradiation induced modest changes in murine cardiac function despite progressive structural damage to the myocardium and microvasculature. Radiotherapy and Oncology, 103(2), 143-150. https://doi.org/10.1016/j.radonc.2011.10.011
    • Donners, M. M. P. C., Wolfs, I. M. J., Stoger, L. J., van der Vorst, E. P. C., Pottgens, C. C. H., Heymans, S., Schroen, B., Gijbels, M. J. J., & de Winther, M. P. J. (2012). Hematopoietic miR155 Deficiency Enhances Atherosclerosis and Decreases Plaque Stability in Hyperlipidemic Mice. PLOS ONE, 7(4), Article e35877. https://doi.org/10.1371/journal.pone.0035877
    • Papageorgiou, A.-P., Swinnen, M., Vanhoutte, D., VandenDriessche, T., Chuah, M., Lindner, D., Verhesen, W., de Vries, B., D'hooge, J., Lutgens, E., Westermann, D., Carmeliet, P., & Heymans, S. (2012). Thrombospondin-2 prevents cardiac injury and dysfunction in viral myocarditis through the activation of regulatory T-cells. Cardiovascular Research, 94(1), 115-124. https://doi.org/10.1093/cvr/cvs077
    • Jin, Y., Kuznetsova, T., Thijs, L., Schmitz, B., Liu, Y., Asayama, K., Brand, S.-M., Heymans, S., Brand, E., Fagard, R., & Staessen, J. A. (2012). Association of Left Ventricular Mass With the AGTR1 A1166C Polymorphism. American Journal of Hypertension, 25(4), 472-478. https://doi.org/10.1038/ajh.2011.244
    • Martins, P. A. D. C., & De Windt, L. J. (2012). MicroRNAs in control of cardiac hypertrophy. Cardiovascular Research, 93(4), 563-572. https://doi.org/10.1093/cvr/cvs013
    • Schroen, B., & Heymans, S. (2012). Small but smart-microRNAs in the centre of inflammatory processes during cardiovascular diseases, the metabolic syndrome, and ageing. Cardiovascular Research, 93(4), 605-613. https://doi.org/10.1093/cvr/cvr268
    • Muzzarelli, S., Maeder, M. T., Toggweiler, S., Rickli, H., Nietlispach, F., Julius, B., Burkard, T., Pfisterer, M. E., & Brunner-La Rocca, H.-P. (2012). Frequency and Predictors of Hyperkalemia in Patients >= 60 Years of Age With Heart Failure Undergoing Intense Medical Therapy. American Journal of Cardiology, 109(5), 693-698. https://doi.org/10.1016/j.amjcard.2011.10.027
    • Burkard, T., Kaiser, C. A., Brunner-La Rocca, H., Osswald, S., Pfisterer, M. E., & Jeger, R. V. (2012). Combined clopidogrel and proton pump inhibitor therapy is associated with higher cardiovascular event rates after percutaneous coronary intervention: a report from the BASKET trial. Journal of Internal Medicine, 271(3), 257-263. https://doi.org/10.1111/j.1365-2796.2011.02423.x
    • Maeder, M. T., Rickli, H., Pfisterer, M. E., Muzzarelli, S., Ammann, P., Fehr, T., Hack, D., Weilenmann, D., Dieterle, T., Kiencke, S., Estlinbaum, W., & Brunner-La Rocca, H.-P. (2012). Incidence, clinical predictors, and prognostic impact of worsening renal function in elderly patients with chronic heart failure on intensive medical therapy. American Heart Journal, 163(3), 407-U353. https://doi.org/10.1016/j.ahj.2011.12.003
    • Devaux, Y., Vausort, M., Goretti, E., Nazarov, P. V., Azuaje, F., Gilson, G., Corsten, M. F., Schroen, B., Lair, M.-L., Heymans, S., & Wagner, D. R. (2012). Use of Circulating MicroRNAs to Diagnose Acute Myocardial Infarction. Clinical Chemistry, 58(3), 559-567. https://doi.org/10.1373/clinchem.2011.173823
    • Zellweger, M. J., Kaiser, C. A., Jeger, R. V., Brunner-La Rocca, H.-P., Buser, P. T., Bader, F., Mueller-Brand, J., & Pfisterer, M. E. (2012). Coronary Artery Disease Progression Late After Successful Stent Implantation. Journal of the American College of Cardiology, 59(9), 793-799. https://doi.org/10.1016/j.jacc.2011.11.024
    • Daskalopoulos, E. P., Janssen, B. J. A., & Blankesteijn, W. M. (2012). Myofibroblasts in the Infarct Area: Concepts and Challenges. Microscopy and Microanalysis, 18(1), 35-49. https://doi.org/10.1017/S143192761101227X
    • Heijman, J., Spätjens, R. L. H., Seyen, S. R. M., Lentink, V., Kuijpers, H. J. H., Boulet, I. R., de Windt, L. J., David, M., & Volders, P. G. A. (2012). Dominant-Negative Control of cAMP-Dependent I-Ks Upregulation in Human Long-QT Syndrome Type 1. Circulation Research, 110(2), 211–219. https://doi.org/10.1161/CIRCRESAHA.111.249482
    • Octavia, Y., Rocca, H. P. B.-L., & Moens, A. L. (2012). NADPH oxidase-dependent oxidative stress in the failing heart: From pathogenic roles to therapeutic approach. Free Radical Biology and Medicine, 52(2), 291-297. https://doi.org/10.1016/j.freeradbiomed.2011.10.482
    • Moalin, M., van Strijdonck, G. P., Bast, A., & Haenen, G. R. M. M. (2012). Competition between Ascorbate and Glutathione for the Oxidized Form of Methylated Quercetin Metabolites and Analogues: Tamarixetin, 4'O-Methylquercetin, Has the Lowest Thiol Reactivity. Journal of Agricultural and Food Chemistry, 60(36), 9292-9297. https://doi.org/10.1021/jf302068v
    • Mateo Anson, N., Hemery, Y. M., Bast, A., & Haenen, G. R. M. M. (2012). Optimizing the bioactive potential of wheat bran by processing. Food & Function, 3(4), 362-375. https://doi.org/10.1039/c2fo10241b
    • van den Heuvel, M. G. W., Bast, A., Haenen, G. R. M. M., Ambergen, A. W., Mermans, J. F., & van der Hulst, R. R. W. J. (2012). The role of antioxidants in ischaemia-reperfusion in a human DIEP flap model. Journal of Plastic Reconstructive and Aesthetic Surgery, 65(12), 1706-1711. https://doi.org/10.1016/j.bjps.2012.06.010
    • van Wijk, S., Jacobs, L., Eurlings, L. W., van Kimmenade, R., Lemmers, R., Broos, P., Bekers, O., Prins, M. H., Crijns, H. J., Pinto, Y. M., van Dieijen-Visser, M. P., & Brunner-La Rocca, H. P. (2012). Troponin T Measurements by High-Sensitivity vs Conventional Assays for Risk Stratification in Acute Dyspnea. Clinical Chemistry, 58(1), 284-292. https://doi.org/10.1373/clinchem.2011.175976
    • Gladka, M. M., Martins, P. A. D. C., & de Windt, L. J. (2012). Small changes can make a big difference - MicroRNA regulation of cardiac hypertrophy. Journal of Molecular and Cellular Cardiology, 52(1), 74-82. https://doi.org/10.1016/j.yjmcc.2011.09.015
    • ter Horst, P., Smits, J. F. M., & Blankesteijn, W. M. (2012). The Wnt/Frizzled pathway as a therapeutic target for cardiac hypertrophy: where do we stand. Acta Physiologica, 204(1), 110-117. https://doi.org/10.1111/j.1748-1716.2011.02309.x
    • Halbach, N. S. J., Smeets, E. E. J., Bierau, J., Keularts, I. M. L. W., Plasqui, G., Julu, P. O. O., Engerström, I. W., Bakker, J. A., & Curfs, L. M. G. (2012). Altered carbon dioxide metabolism and creatine abnormalities in rett syndrome. JIMD reports, 3, 117-24. https://doi.org/10.1007/8904_2011_76
  • 2011
    • Spijkers, L. J. A., Janssen, B. J. A., Nelissen, J., Meens, M. J. P. M. T., Wijesinghe, D. S., Chalfant, C. E., De Mey, J. G. R., Alewijnse, A. E., & Peters, S. L. M. (2011). Antihypertensive Treatment Differentially Affects Vascular Sphingolipid Biology in Spontaneously Hypertensive Rats. PLOS ONE, 6(12), Article e29222. https://doi.org/10.1371/journal.pone.0029222
    • Nabben, M., Hoeks, J., Kornips, C. F. P., Van Beurden, D., Briedé, J. J., Hesselink, M. K. C., Glatz, J. F., & Schrauwen, P. (2011). Significance of uncoupling protein 3 in mitochondrial function upon mid- and long-term dietary high-fat exposure. Febs Letters, 585(24), 4010-4017. https://doi.org/10.1016/j.febslet.2011.11.012
    • Weseler, A. R., Ruijters, E. J. B., Reesink, K. D., Haenen, G. R. M. M., & Bast, A. (2011). Pleiotropic benefit of monomeric and oligomeric flavanols on vascular health - a randomized controlled clinical pilot study. PLOS ONE, 6(12), Article 28460. https://doi.org/10.1371/journal.pone.0028460
    • Jacobs, H., Moalin, M., van Gisbergen, M. W., Bast, A., van der Vijgh, W. J. F., & Haenen, G. R. M. M. (2011). An essential difference in the reactivity of the glutathione adducts of the structurally closely related flavonoids monoher and quercetin. Free Radical Biology and Medicine, 51(11), 2118-2123. https://doi.org/10.1016/j.freeradbiomed.2011.09.013
    • Jacobs, H., Koek, G. H., Peters, R., Moalin, M., Tack, J., van der Vijgh, W. J. F., Bast, A., & Haenen, G. R. M. M. (2011). Differences in pharmacological activities of the antioxidant flavonoid monoher in humans and mice are caused by variations in its metabolic profile. Clinical Pharmacology & Therapeutics, 90(6), 852-859. https://doi.org/10.1038/clpt.2011.200
    • Bartelds, B., Borgdorff, M. A., Smit-van Oosten, A., Takens, J., Boersma, B., Nederhoff, M. G., Elzenga, N. J., van Gilst, W. H., De Windt, L. J., & Berger, R. M. F. (2011). Differential responses of the right ventricle to abnormal loading conditions in mice: pressure vs. volume load. European journal of heart failure, 13(12), 1275-1282. https://doi.org/10.1093/eurjhf/hfr134
    • He, B. J., Joiner, M. A., Singh, M. V., Luczak, E. D., Swaminathan, P. D., Koval, O. M., Kutschke, W., Allamargot, C., Yang, J., Guan, X., Zimmerman, K., Grumbach, I. M., Weiss, R. M., Spitz, D. R., Sigmund, C. D., Blankesteijn, W. M., Heymans, S., Mohler, P. J., & Anderson, M. E. (2011). Oxidation of CaMKII determines the cardiotoxic effects of aldosterone. Nature Medicine, 17(12), 1610-U125. https://doi.org/10.1038/nm.2506
    • Heijnen, B. F. J., Peutz-Kootstra, C. J., Mullins, J. J., Janssen, B. J. A., & Struijker-Boudier, H. A. J. (2011). Transient renin-angiotensin system stimulation in an early stage of life causes sustained hypertension in rats. Journal of Hypertension, 29(12), 2369-2380. https://doi.org/10.1097/HJH.0b013e32834cfcf4
    • Armand, A.-S., Laziz, I., Djeghloul, D., Lecolle, S., Bertrand, A. T., Biondi, O., De Windt, L. J., & Chanoine, C. (2011). Apoptosis-Inducing Factor Regulates Skeletal Muscle Progenitor Cell Number and Muscle Phenotype. PLOS ONE, 6(11), 15. https://doi.org/10.1371/journal.pone.0027283
    • Moalin, M., van Strijdonck, G. P., Beckers, M., Hageman, G., Borm, P., Bast, A., & Haenen, G. R. M. M. (2011). A planar conformation and the hydroxyl groups in the b and c rings play a pivotal role in the antioxidant capacity of quercetin and quercetin derivatives. Molecules, 16(11), 9636-9650. https://doi.org/10.3390/molecules16119636
    • Laeremans, H., Hackeng, T. M., van Zandvoort, M. A. M. J., Thijssen, V. L. J. L., Janssen, B. J. A., Ottenheijm, H. C. J., Smits, J. F. M., & Blankesteijn, W. M. (2011). Blocking of Frizzled Signaling With a Homologous Peptide Fragment of Wnt3a/Wnt5a Reduces Infarct Expansion and Prevents the Development of Heart Failure After Myocardial Infarction. Circulation, 124(15), 1626-U107. https://doi.org/10.1161/CIRCULATIONAHA.110.976969
    • van Almen, G. C., Verhesen, W., van Leeuwen, R. E. W., van de Vrie, M., Eurlings, C., Schellings, M. W. M., Swinnen, M., Cleutjens, J. P. M., van Zandvoort, M. A. M. J., Heymans, S., & Schroen, B. (2011). MicroRNA-18 and microRNA-19 regulate CTGF and TSP-1 expression in age-related heart failure. Aging Cell, 10(5), 769-779. https://doi.org/10.1111/j.1474-9726.2011.00714.x
    • Wingler, K., Hermans, J. J. R., Schiffers, P., Moens, A. L., Paul, M., & Schmidt, H. H. H. W. (2011). NOX1, 2, 4, 5: counting out oxidative stress. British Journal of Pharmacology, 164(3), 866-883. https://doi.org/10.1111/j.1476-5381.2011.01249.x
    • Anson, N. M., Havenaar, R., Vaes, W., Coulier, L., Venema, K., Selinheimo, E., Bast, A., & Haenen, G. R. M. M. (2011). Effect of bioprocessing of wheat bran in wholemeal wheat breads on the colonic SCFA production in vitro and postprandial plasma concentrations in men. Food Chemistry, 128(2), 404-409. https://doi.org/10.1016/j.foodchem.2011.03.043
    • van Almen, G. C., Swinnen, M., Carai, P., Verhesen, W., Cleutjens, J. P. M., D'hooge, J., Verheyen, F. K., Pinto, Y. M., Schroen, B., Carmeliet, P., & Heymans, S. (2011). Absence of thrombospondin-2 increases cardiomyocyte damage and matrix disruption in doxorubicin-induced cardiomyopathy. Journal of Molecular and Cellular Cardiology, 51(3), 318-328. https://doi.org/10.1016/j.yjmcc.2011.05.010
    • Maitland-van der Zee, A.-H., van Wieren-de Wijer, D. B. M. A., de Boer, A., Kroon, A. A., de Leeuw, P. W., Schiffers, P., Janssen, R. G. J. H., Psaty, B. M., Duijn, C. M. V., Stricker, B. H. C., & Klungel, O. H. (2011). Genetic variation in the renin-angiotensin system, use of renin-angiotensin system inhibitors and the risk of myocardial infarction. Journal of the Renin-angiotensin-aldosterone System, 12(3), 208-214. https://doi.org/10.1177/1470320310391834
    • Olieslagers, S., Pardali, E., Tchaikovski, V., ten Dijke, P., & Waltenberger, J. (2011). TGF-beta 1/ALK5-induced monocyte migration involves PI3K and p38 pathways and is not negatively affected by diabetes mellitus. Cardiovascular Research, 91(3), 510-518. https://doi.org/10.1093/cvr/cvr100
    • Spijkers, L. J. A., van den Akker, R. F. P., Janssen, B. J. A., Debets, J. J., De Mey, J. G. R., Stroes, E. S. G., van den Born, B.-J. H., Wijesinghe, D. S., Chalfant, C. E., MacAleese, L., Eijkel, G. B., Heeren, R. M. A., Alewijnse, A. E., & Peters, S. L. M. (2011). Hypertension Is Associated with Marked Alterations in Sphingolipid Biology: A Potential Role for Ceramide. PLOS ONE, 6(7), 9. https://doi.org/10.1371/journal.pone.0021817
    • Meens, M. J. P. M. T., Mattheij, N. J. A., Nelissen, J., Lemkens, P., Compeer, M. G., Janssen, B. J. A., & De Mey, J. G. R. (2011). Calcitonin Gene-Related Peptide Terminates Long-Lasting Vasopressor Responses to Endothelin 1 In Vivo. Hypertension, 58(1), 99-U181. https://doi.org/10.1161/HYPERTENSIONAHA.110.169128
    • Verkaar, F., van der Stelt, M., Blankesteijn, W. M., van der Doelen, A. A., & Zaman, G. J. R. (2011). Discovery of Novel Small Molecule Activators of beta-Catenin Signaling. PLOS ONE, 6(4), 7. https://doi.org/10.1371/journal.pone.0019185
    • Verkaar, F., van der Doelen, A. A., Smits, J. F. M., Blankesteijn, W. M., & Zaman, G. J. R. (2011). Inhibition of Wnt/beta-Catenin Signaling by p38 MAP Kinase Inhibitors Is Explained by Cross-Reactivity with Casein Kinase I delta/epsilon. Chemistry & Biology, 18(4), 485-494. https://doi.org/10.1016/j.chembiol.2011.01.015
    • el Azzouzi, H., Leptidis, S., Bourajjaj, M., Armand, A.-S., van der Nagel, R., van Bilsen, M., Martins, P. A. D. C., & De Windt, L. J. (2011). Peroxisome Proliferator-activated Receptor (PPAR) Gene Profiling Uncovers Insulin-like Growth Factor-1 as a PPAR alpha Target Gene in Cardioprotection. Journal of Biological Chemistry, 286(16), 14598-14607. https://doi.org/10.1074/jbc.M111.220525
    • Perino, A., Ghigo, A., Ferrero, E., More, F., Santulli, G., Baillie, G. S., Damilano, F., Dunlop, A. J., Pawson, C., Walser, R., Levi, R., Altruda, F., Silengo, L., Langeberg, L. K., Neubauer, G., Heymans, S., Lembo, G., Wymann, M. P., Wetzker, R., ... Hirsch, E. (2011). Integrating Cardiac PIP3 and cAMP Signaling through a PKA Anchoring Function of p110 gamma. Molecular Cell, 42(1), 84-95. https://doi.org/10.1016/j.molcel.2011.01.030
    • Mischke, K., Knackstedt, C., Fache, K., Reith, S., Rana, O., Saygili, E., Gemein, C., Becker, M., Marx, N., & Schauerte, P. (2011). Electrical remodelling in cardiac resynchronization therapy: decrease in intrinsic QRS duration. Acta Cardiologica, 66(2), 175-180. https://doi.org/10.1080/AC.66.2.2071248