Manukjan, N., Fulton, D., Ahmed, Z., Blankesteijn, W. M., & Foulquier, S. (2025). Vascular endothelial growth factor: a double-edged sword in the development of white matter lesions. Neural Regeneration Research, 20(1), 191-192. https://doi.org/10.4103/NRR.NRR-D-23-01843

Berends, E., Pencheva, M. G., van de Waarenburg, M. P. H., Scheijen, J. L. J. M., Hermes, D. J. H. P., Wouters, K., van Oostenbrugge, R. J., Foulquier, S., & Schalkwijk, C. G. (2024). Glyoxalase 1 overexpression improves neurovascular coupling and limits development of mild cognitive impairment in a mouse model of type 1 diabetes. Journal of Physiology, 602(22), 6209-6223. https://doi.org/10.1113/JP286723

Berends, E., Vangrieken, P., Amiri, N., van de Waarenburg, M. P. H., Scheijen, J. L. J. M., Hermes, D. J. H. P., Wouters, K., van Oostenbrugge, R. J., Schalkwijk, C. G., & Foulquier, S. (2024). Increased Levels of Circulating Methylglyoxal Have No Consequence for Cerebral Microvascular Integrity and Cognitive Function in Young Healthy Mice. Molecular Neurobiology. Advance online publication. https://doi.org/10.1007/s12035-024-04552-3

Piët, J. D., Booth, A., Donker, E. M., de Ponti, F., Lunghi, C., Poluzzi, E., Janssen, B. J. A., Tun, S., Bekker, C., Dima, L., Costa, J., Jalving, M., Oude Munnink, T. H., van den Bemt, P. M. L. A., Labriffe, M., van Emden, T., van Waardenburg, V., Likic, R., Richir, M., ... Tichelaar, J. (2024). Environmentally sustainable prescribing: recommendations for EU pharmaceutical legislation. The Lancet. Planetary health, 8(10), e715-e716. https://doi.org/10.1016/S2542-5196(24)00230-4

Li, Z., Xu, L., Huang, D., Li, C., Haenen, G. R. M. M., & Zhang, M. (2024). NR0B2 Is a Key Factor for Gastric Diseases: A GEO Database Analysis Combined with Drug-Target Mendelian Randomization. Genes, 15(9), Article 1210. https://doi.org/10.3390/genes15091210

Vangrieken, P., Al-Nasiry, S., Remels, A. H. V., Schiffers, P. M. H., Janssen, E., Nass, S., Scheijen, J. L. J. M., Spaanderman, M. E. A., & Schalkwijk, C. G. (2024). Placental Methylglyoxal in Preeclampsia: Vascular and Biomarker Implications. Hypertension, 81(7), 1537-1549. https://doi.org/10.1161/HYPERTENSIONAHA.123.22633

Manukjan, N., Chau, S., Caiment, F., van Herwijnen, M., Smeets, H. J., Fulton, D., Ahmed, Z., Blankesteijn, W. M., & Foulquier, S. (2024). Wnt7a Decreases Brain Endothelial Barrier Function Via β-Catenin Activation. Molecular Neurobiology, 61(7), 4854-4867. https://doi.org/10.1007/s12035-023-03872-0

van der Laan, K. W. F., Reesink, K. D., Lambrichts, S., Bitsch, N. J. J. E., van der Taelen, L., Foulquier, S., Delhaas, T., Spronck, B., & Giudici, A. (2024). Effect of rapid cooling, frozen storage, and thawing on the passive viscoelastic properties and structure of the rat aorta. Journal of Biomechanics, 171, Article 112190. https://doi.org/10.1016/j.jbiomech.2024.112190

Pinckaers, N. E. T., Blankesteijn, W. M., Mircheva, A., Shi, X., Opperhuizen, A., van Schooten, F.-J., & Vrolijk, M. F. (2024). In Vitro Activation of Human Adrenergic Receptors and Trace Amine-Associated Receptor 1 by Phenethylamine Analogues Present in Food Supplements. Nutrients, 16(11), Article 1567. https://doi.org/10.3390/nu16111567

Donker, E. M., Osmani, H., Brinkman, D. J., van Rosse, F., Janssen, B., Knol, W., Dumont, G., Jorens, P. G., Dupont, A., Christiaens, T., van Smeden, J., de Waard-Siebinga, I., Peeters, L. E. J., Goorden, R., Hessel, M., Lissenberg-Witte, B. I., Richir, M. C., van Agtmael, M. A., Kramers, C., ... Education committee of the Dutch Society for Clinical Pharmacology and Biopharmacy (2023). The impact of a summative national prescribing assessment and curriculum type on the development of the prescribing competence of junior doctors. European Journal of Clinical Pharmacology, 79(12), 1613 - 1621. https://doi.org/10.1007/s00228-023-03567-4

Nelissen, E., Schepers, M., Ponsaerts, L., Foulquier, S., Bronckaers, A., Vanmierlo, T., Sandner, P., & Prickaerts, J. (2023). Soluble guanylyl cyclase: A novel target for the treatment of vascular cognitive impairment?Pharmacological Research, 197(1), Article 106970. https://doi.org/10.1016/j.phrs.2023.106970

Berends, E., van Oostenbrugge, R. J., Foulquier, S., & Schalkwijk, C. G. (2023). Methylglyoxal, a highly reactive dicarbonyl compound, as a threat for blood brain barrier integrity. Fluids and barriers of the CNS, 20(1), Article 75. https://doi.org/10.1186/s12987-023-00477-6

Giudici, A., van der Laan, K. W. F., van der Bruggen, M. M., Parikh, S., Berends, E., Foulquier, S., Delhaas, T., Reesink, K. D., & Spronck, B. (2023). Constituent-based quasi-linear viscoelasticity: a revised quasi-linear modelling framework to capture nonlinear viscoelasticity in arteries. Biomechanics and modeling in mechanobiology, 22(5), 1607–1623. https://doi.org/10.1007/s10237-023-01711-8

Xu, Y., Li, Z., Wang, Y., Li, C., Zhang, M., Chen, H., Chen, W., Zhong, Q., Pei, J., Chen, W., Haenen, G. R. M. M., & Moalin, M. (2023). Unraveling the Antioxidant Activity of 2R,3R-dihydroquercetin. International Journal of Molecular Sciences, 24(18), Article 14220. https://doi.org/10.3390/ijms241814220

Manukjan, N., Majcher, D., Leenders, P., Caiment, F., van Herwijnen, M., Smeets, H. J. J., Suidgeest, E., van der Weerd, L., Vanmierlo, T., Jansen, J. F. A., Backes, W. H. H., van Oostenbrugge, R. J. J., Staals, J., Fulton, D., Ahmed, Z., Blankesteijn, W. M., & Foulquier, S. (2023). Hypoxic oligodendrocyte precursor cell-derived VEGFA is associated with blood-brain barrier impairment. Acta neuropathologica communications, 11(1), Article 128. https://doi.org/10.1186/s40478-023-01627-5

Kerkhofs, D., Helgers, R., Hermes, D., Steinbusch, H. P. J., Van Essen, H., Leenders, P., Prickaerts, J., Staals, J., Biessen, E. A., Van Oostenbrugge, R. J., & Foulquier, S. (2023). Amlodipine limits microglia activation and cognitive dysfunction in aged hypertensive mice. Journal of Hypertension, 41(7), 1159-1167. https://doi.org/10.1097/HJH.0000000000003445

Colin, M., Delaitre, C., Foulquier, S., & Dupuis, F. (2023). The AT(1)/AT(2) Receptor Equilibrium Is a Cornerstone of the Regulation of the Renin Angiotensin System beyond the Cardiovascular System. Molecules, 28(14), Article 5481. https://doi.org/10.3390/molecules28145481

Haenen, G. R. M. M. (2023). Past, Present and Future of the Section "Molecular Toxicology". International Journal of Molecular Sciences, 24(7), Article 6667. https://doi.org/10.3390/ijms24076667

Donker, E. M., Pandit, R., Poleij, M. C. S., Brinkman, D. J., van Agtmael, M. A., van Rosse, F., Dumont, G., Kramers, C., Atiqi, R., Richir, M. C., van Smeden, J., Hessel, M. H. M., Janssen, B. J., Knol, W., Tichelaar, J., & Pharmacotherapy Education working group of the Dutch Society for Clinical Pharmacology & Biopharmacy and its affiliated Dutch Network of Clinical Pharmacology Teachers (2023). The Dutch list of essential drugs for undergraduate medical education: A modified Delphi study. British Journal of Clinical Pharmacology, 89(4), 1431-1451. https://doi.org/10.1111/bcp.15606

Donker, E. M., Brinkman, D. J., van Rosse, F., Janssen, B., Knol, W., Dumont, G., Jorens, P. G., Dupont, A., Christiaens, T., van Smeden, J., de Waard-Siebinga, I., Peeters, L. E. J., Goorden, R., Hessel, M., Lissenberg-Witte, B., Richir, M., van Agtmael, M., Kramers, C., Tichelaar, J., & Education committee of the Dutch Society for Clinical Pharmacology and Biopharmacy (2022). Do we become better prescribers after graduation: A 1-year international follow-up study among junior doctors. British Journal of Clinical Pharmacology, 88(12), 5218-5226. https://doi.org/10.1111/bcp.15443

Douven, P., Franken, G., Debets, J., Joosten, E. A., Van Koeveringe, G. A., Melenhorst, J., & Breukink, S. O. (2022). Vaginal Distention Rodent Model for Fecal Incontinence: A Pilot Study on the Effect on Defecation Behavior. Journal of Coloproctology, 42(3), 217-222. https://doi.org/10.1055/s-0042-1750074

Pinckaers, N., Blankesteijn, M., Opperhuizen, A., Van Schooten, F. J., & Vrolijk, M. (2022). In vitro pharmacological characterization of phenethylamine and alkylamine analogues found in nutritional supplements at human adrenergic and trace amine-associated receptors. Toxicology Letters, 368, S280-S280. https://doi.org/10.1016/j.toxlet.2022.07.739

Kemps, H., Dessy, C., Dumas, L., Sonveaux, P., Alders, L., Van Broeckhoven, J., Font, L. P., Lambrichts, S., Foulquier, S., Hendrix, S., Brône, B., Lemmens, R., & Bronckaers, A. (2022). Extremely low frequency electromagnetic stimulation reduces ischemic stroke volume by improving cerebral collateral blood flow. Journal of Cerebral Blood Flow and Metabolism, 42(6), 979-996. Article 0271678X221084410. https://doi.org/10.1177/0271678X221084410

Neradova, A., Wasilewski, G., Prisco, S., Leenders, P., Caron, M., Welting, T., van Rietbergen, B., Kramann, R., Floege, J., Vervloet, M. G., & Schurgers, L. J. (2022). Combining phosphate binder therapy with vitamin K2 inhibits vascular calcification in an experimental animal model of kidney failure. Nephrology Dialysis Transplantation, 37(4), 652-662. https://doi.org/10.1093/ndt/gfab314

Li, Z., Zhang, M., Haenen, G. R. M. M., Vervoort, L., & Moalin, M. (2022). Flavonoids Seen through the Energy Perspective. International Journal of Molecular Sciences, 23(1), Article 187. https://doi.org/10.3390/ijms23010187

Segers, F. M. E., Ruder, A. V., Westra, M. M., Lammers, T., Dadfar, S. M., Roemhild, K., Lam, T. S., Eline Kooi, M., Cleutjens, K. B. J. M., Verheyen, F. K., Schurink, G. W. H., Haenen, G. R., van Berkel, T. J. C., Bot, I., Halvorsen, B., Sluimer, J. C., & Biessen, E. A. L. (2022). Magnetic resonance imaging contrast-enhancement with superparamagnetic iron oxide nanoparticles amplifies macrophage foam cell apoptosis in human and murine atherosclerosis. Cardiovascular Research, 118, 3346-3359. https://doi.org/10.1093/cvr/cvac032

Jedrzejczyk, M. A., Van den Bosch, S., Van Aelst, J., Van Aelst, K., Kouris, P. D., Moalin, M., Haenen, G. R. M. M., Boot, M. D., Hensen, E. J. M., Lagrain, B., Sels, B. F., & Bernaerts, K. V. (2021). Lignin-Based Additives for Improved Thermo-Oxidative Stability of Biolubricants. ACS Sustainable Chemistry & Engineering, 9(37), 12548-12559. https://doi.org/10.1021/acssuschemeng.1c02799

van Gorp, R. H., Baaten, C. C. F. M. J., Habibi, A., Jaminon, A. M. G., Peeters, F. E. C. M., Leenders, P., Crijns, H. J. G. M. C., Heemskerk, J. W. M., Reutelingsperger, C. P., Spronk, H. M., & Schurgers, L. J. (2021). Vitamin K antagonist use induces calcification and atherosclerotic plaque progression resulting in increased hypercoagulability. European heart journal open, 1(2), Article oeab017. https://doi.org/10.1093/ehjopen/oeab017

Laukkanen, L., Diniz, C. R. A. F., Foulquier, S., Prickaerts, J., Castren, E., & Casarotto, P. C. (2021). Facilitation of TRKB Activation by the Angiotensin II Receptor Type-2 (AT2R) Agonist C21. Pharmaceuticals, 14(8), Article 773. https://doi.org/10.3390/ph14080773

Vangrieken, P., Al-Nasiry, S., Bast, A., Leermakers, P. A., Tulen, C. B. M., Schiffers, P. M. H., van Schooten, F. J., & Remels, A. H. V. (2021). Placental Mitochondrial Abnormalities in Preeclampsia. Reproductive Sciences, 28(8), 2186-2199. https://doi.org/10.1007/s43032-021-00464-y

Franken, G., Douven, P., Debets, J., & Joosten, E. A. J. (2021). Conventional Dorsal Root Ganglion Stimulation in an Experimental Model of Painful Diabetic Peripheral Neuropathy: A Quantitative Immunocytochemical Analysis of Intracellular gamma-Aminobutyric Acid in Dorsal Root Ganglion Neurons. Neuromodulation, 24(4), 639-645. https://doi.org/10.1111/ner.13398

van Gorp, R. H., Dijkgraaf, I., Bröker, V., Bauwens, M., Leenders, P., Jennen, D., Dweck, M. R., Bucerius, J., Briedé, J. J., van Ryn, J., Brandenburg, V., Mottaghy, F., Spronk, H. M. H., Reutelingsperger, C. P., & Schurgers, L. J. (2021). Off-target effects of oral anticoagulants - vascular effects of vitamin K antagonist and non-vitamin K antagonist oral anticoagulant dabigatran etexilate. Journal of Thrombosis and Haemostasis, 19(5), 1348-1363. https://doi.org/10.1111/jth.15289

Gouweleeuw, L., Wajant, H., Maier, O., Eisel, U. L. M., Blankesteijn, W. M., & Schoemaker, R. G. (2021). Effects of selective TNFR1 inhibition or TNFR2 stimulation, compared to non-selective TNF inhibition, on (neuro)inflammation and behavior after myocardial infarction in male mice. Brain Behavior and Immunity, 93, 156-171. https://doi.org/10.1016/j.bbi.2021.01.001

Daskalopoulos, E. P., & Blankesteijn, W. M. (2021). Effect of Interventions in WNT Signaling on Healing of Cardiac Injury: A Systematic Review. Cells, 10(2), Article 207. https://doi.org/10.3390/cells10020207

Vangrieken, P., Al-Nasiry, S., Bast, A., Leermakers, P. A., Tulen, C. B. M., Janssen, G. M. J., Kaminski, I., Geomini, I., Lemmens, T., Schiffers, P. M. H., van Schooten, F. J., & Remels, A. H. V. (2021). Hypoxia-induced mitochondrial abnormalities in cells of the placenta. PLOS ONE, 16(1), Article 0245155. https://doi.org/10.1371/journal.pone.0245155

Vangrieken, P., Remels, A. H., Al-Nasiry, S., Bast, A., Janssen, G. M. J., von Rango, U., Vroomans, D., Pinckers, Y. C. W., van Schooten, F. J., & Schiffers, P. M. H. (2020). Placental hypoxia-induced alterations in vascular function, morphology, and endothelial barrier integrity. Hypertension Research, 43(12), 1361-1374. https://doi.org/10.1038/s41440-020-0528-8

Reinhold, S., Blankesteijn, W. M., & Foulquier, S. (2020). The Interplay of WNT and PPARγ Signaling in Vascular Calcification. Cells, 9(12), Article 2658. https://doi.org/10.3390/cells9122658

Mastenbroek, T. G., Karel, M. F. A., Nagy, M., Chayoua, W., Korsten, E. I. J., Coenen, D. M., Debets, J., Konings, J., Brouns, A. E., Leenders, P. J. A., van Essen, H., van Oerle, R., Heitmeier, S., Spronk, H. M., Kuijpers, M. J. E., & Cosemans, J. M. E. M. (2020). Vascular protective effect of aspirin and rivaroxaban upon endothelial denudation of the mouse carotid artery. Scientific Reports, 10(1), Article 19360. https://doi.org/10.1038/s41598-020-76377-8

Elbatreek, M. H., Sadegh, S., Anastasi, E., Guney, E., Nogales, C., Kacprowski, T., Hassan, A. A., Teubner, A., Huang, P.-H., Hsu, C.-Y., Schiffers, P. M. H., Janssen, G. M., Kleikers, P. W. M., Wipat, A., Baumbach, J., De Mey, J. G. R., & Schmidt, H. H. H. W. (2020). NOX5-induced uncoupling of endothelial NO synthase is a causal mechanism and theragnostic target of an age-related hypertension endotype. Plos Biology, 18(11), Article 3000885. https://doi.org/10.1371/journal.pbio.3000885

Li, Z., Moalin, M., Zhang, M., Vervoort, L., Hursel, E., Mommers, A., & Haenen, G. R. M. M. (2020). The Flow of the Redox Energy in Quercetin during Its Antioxidant Activity in Water. International journal of molecular sciences, 21(17), Article 6015. https://doi.org/10.3390/ijms21176015

Kerkhofs, D., van Hagen, B. T., Milanova, I. V., Schell, K. J., van Essen, H., Wijnands, E., Goossens, P., Blankesteijn, W. M., Unger, T., Prickaerts, J., Biessen, E. A., van Oostenbrugge, R. J., & Foulquier, S. (2020). Pharmacological depletion of microglia and perivascular macrophages prevents Vascular Cognitive Impairment in Ang II-induced hypertension. Theranostics, 10(21), 9512-9527. https://doi.org/10.7150/thno.44394

Manukjan, N., Ahmed, Z., Fulton, D., Blankesteijn, W. M., & Foulquier, S. (2020). A Systematic Review of WNT Signaling in Endothelial Cell Oligodendrocyte Interactions: Potential Relevance to Cerebral Small Vessel Disease. Cells, 9(6), 1-15. Article 1545. https://doi.org/10.3390/cells9061545

Vrolijk, M. F., van Essen, H., Opperhuizen, A., Bast, A., & Janssen, B. J. (2020). Haemodynamic effects of the flavonoid quercetin in rats revisited. British Journal of Pharmacology, 177(8), 1841-1852. https://doi.org/10.1111/bph.14955

Li, Z. W., Moalin, M., Zhang, M., Vervoort, L., Mommers, A., & Haenen, G. R. M. M. (2020). Delocalization of the Unpaired Electron in the Quercetin Radical: Comparison of Experimental ESR Data with DFT Calculations. International Journal of Molecular Sciences, 21(6), Article 2033. https://doi.org/10.3390/ijms21062033

Vangrieken, P., Al-Nasiry, S., Bast, A., Leermakers, P. A., Tulen, C. B. M., Janssen, G. M. J., Schiffers, P. M. H., van Schooten, F. J., & Remels, A. H. V. (2020). Placental Mitochondrial Abnormalities Upon Hypoxia; The Cause of Placental Oxidative Stress?Reproductive Sciences, 27(SUPPL 1), 268A-268A.

Blankesteijn, W. M. (2020). Interventions in WNT Signaling to Induce Cardiomyocyte Proliferation: Crosstalk with Other Pathways. Molecular Pharmacology, 97(2), 90-101. https://doi.org/10.1124/mol.119.118018

Foulquier, S. (2020). Brain perivascular macrophages: connecting inflammation to autonomic activity in hypertension. Hypertension Research, 43(2), 148-150. https://doi.org/10.1038/s41440-019-0359-7

Koetsier, E., Franken, G., Debets, J., van Kuijk, S. M. J., Linderoth, B., Joosten, E. A., & Maino, P. (2020). Dorsal Root Ganglion Stimulation in Experimental Painful Diabetic Polyneuropathy: Delayed Wash-Out of Pain Relief After Low-Frequency (1Hz) Stimulation. Neuromodulation, 23(2), 177-184. https://doi.org/10.1111/ner.13048

Franken, G., Debets, J., & Joosten, E. A. J. (2020). Nonlinear Relation Between Burst Dorsal Root Ganglion Stimulation Amplitude and Behavioral Outcome in an Experimental Model of Painful Diabetic Peripheral Neuropathy. Neuromodulation, 23(2), 158-166. https://doi.org/10.1111/ner.13070