• 2020
    • Luiken, J. J. F. P., Nabben, M., Neumann, D., & Glatz, J. F. C. (2020). Understanding the distinct subcellular trafficking of CD36 and GLUT4 during the development of myocardial insulin resistance. Biochimica et Biophysica Acta-Molecular Basis of Disease, 1866(7), Article 165775. https://doi.org/10.1016/j.bbadis.2020.165775
    • Summer, G., Kuhn, A. R., Munts, C., Miranda-Silva, D., Leite-Moreira, A. F., Lourenco, A. P., Heymans, S., Falcao-Pires, I., & van Bilsen, M. (2020). A directed network analysis of the cardiome identifies molecular pathways contributing to the development of HFpEF. Journal of Molecular and Cellular Cardiology, 144, 66-75. https://doi.org/10.1016/j.yjmcc.2020.05.008
    • Santos-Faria, J., Gavina, C., Rodrigues, P., Coelho, J., Martins, P. D. C., Leite-Moreira, A., & Falcao-Pires, I. (2020). MicroRNAs and ventricular remodeling in aortic stenosis. Revista portuguesa de cardiologia, 39(7), 377-387. https://doi.org/10.1016/j.repc.2019.09.014
    • Brunner-La Rocca, H.-P., Peden, C. J., Soong, J., Holman, P. A., Bogdanovskaya, M., & Barclay, L. (2020). Reasons for readmission after hospital discharge in patients with chronic diseases-Information from an international dataset. PLOS ONE, 15(6), Article 0233457. https://doi.org/10.1371/journal.pone.0233457
    • Linssen, P. B. C., Veugen, M. G. J., Henry, R. M. A., van Der Kallen, C. J. H., Kroon, A. A., Schram, M. T., Brunner-La Rocca, H.-P., & Stehouwer, C. D. A. (2020). Associations of (pre)diabetes with right ventricular and atrial structure and function: the Maastricht Study. Cardiovascular Diabetology, 19(1), Article 88. https://doi.org/10.1186/s12933-020-01055-y
    • Veenis, J. F., Brunner-La Rocca, H. P., Linssen, G. C. M., Smeele, F. J. J., Wouters, N. T. A. E., Westendorp, P. H. M., Rademaker, P. C., Hemels, M. E. W., Rienstra, M., Hoes, A. W., Brugts, J. J., & CHECK-HF Investigators (2020). Atrial fibrillation in chronic heart failure patients with reduced ejection fraction: The CHECK-HF registry. International Journal of Cardiology, 308, 60-66. https://doi.org/10.1016/j.ijcard.2020.03.001
    • De Majo, F., & da Costa Martins, P. A. (2020). CircRNAs in the heart: bricks in Brunelleschi's Dome. Cardiovascular Research, 116(7), 1240-1241. https://doi.org/10.1093/cvr/cvaa020
    • Linssen, G. C. M., Veenis, J. F., Brunner-La Rocca, H. P., van Pol, P. E. J., Engelen, D. J. M., van Tooren, R. M., Koornstra-Wortel, H. J. J., Hoes, A. W., Brugts, J. J., & CHECK-HF Investigators (2020). Differences in guideline-recommended heart failure medication between Dutch heart failure clinics: an analysis of the CHECK-HF registry. Netherlands Heart Journal, 28(6), 334-344. https://doi.org/10.1007/s12471-020-01421-1
    • Simonavicius, J., Puronaite, R., & Brunner-La Rocca, H. P. (2020). The Reply. American Journal of Medicine, 133(6), E330-E332. https://doi.org/10.1016/j.amjmed.2019.12.011
    • Verdonschot, J. A. J., Vanhoutte, E. K., Claes, G. R. F., van den Enden, A. T. J. M. H., Hoeijmakers, J. G. J., Hellebrekers, D. M. E. I., Haan, A. D., Christiaans, I., Deprez, R. H. L., Boen, H. M., Craenenbroeck, E. M. V., Loeys, B. L., Hoedemaekers, Y. M., Marcelis, C., Kempers, M., Brusse, E., Waning, J. I., Baas, A. F., Dooijes, D., ... Brunner, H. G. (2020). A mutation update for the FLNC gene in myopathies and cardiomyopathies. Human Mutation, 41(6), 1091-1111. https://doi.org/10.1002/humu.24004
    • Manukjan, N., Ahmed, Z., Fulton, D., Blankesteijn, W. M., & Foulquier, S. (2020). A Systematic Review of WNT Signaling in Endothelial Cell Oligodendrocyte Interactions: Potential Relevance to Cerebral Small Vessel Disease. Cells, 9(6), Article 1545. https://doi.org/10.3390/cells9061545
    • Suthahar, N., Meems, L. M. G., van Veldhuisen, D. J., Walter, J. E., Gansevoort, R. T., Heymans, S., Schroen, B., van der Harst, P., Kootstra-Ros, J. E., van Empel, V., Mueller, C., Bakker, S. J. L., & de Boer, R. A. (2020). High-Sensitivity Troponin-T and Cardiovascular Outcomes in the Community: Differences Between Women and Men. Mayo Clinic Proceedings, 95(6), 1158-1168. https://doi.org/10.1016/j.mayocp.2020.01.017
    • Cuijpers, I., Simmonds, S. J., van Bilsen, M., Czarnowska, E., Miqueo, A. G., Heymans, S., Kuhn, A. R., Mulder, P., Ratajska, A., Jones, E. A., & Brakenhielm, E. (2020). Microvascular and lymphatic dysfunction in HFpEF and its associated comorbidities. Basic Research in Cardiology, 115(4), Article 39. https://doi.org/10.1007/s00395-020-0798-y
    • De Majo, F., Hegenbarth, J.-C., Ruehle, F., Baer, C., Thum, T., de Boer, M., Duncker, D. J., Schroen, B., Armand, A.-S., Stoll, M., & De Windt, L. J. (2020). Dichotomy between the transcriptomic landscape of naturally versus accelerated aged murine hearts. Scientific Reports, 10(1), Article 8136. https://doi.org/10.1038/s41598-020-65115-9
    • Sacchetto, C., Vitiello, L., de Windt, L. J., Rampazzo, A., & Calore, M. (2020). Modeling Cardiovascular Diseases with hiPSC-Derived Cardiomyocytes in 2D and 3D Cultures. International Journal of Molecular Sciences, 21(9), Article 3404. https://doi.org/10.3390/ijms21093404
    • Glatz, J. F. C., Nabben, M., Young, M. E., Schulze, P. C., Taegtmeyer, H., & Luiken, J. J. F. P. (2020). Re-balancing cellular energy substrate metabolism to mend the failing heart. Biochimica et Biophysica Acta-Molecular Basis of Disease, 1866(5), Article 165579. https://doi.org/10.1016/j.bbadis.2019.165579
    • Veenis, J. F., Brunner-La Rocca, H. P., Linssen, G. C. M., Van Gent, M. W. F., Hoes, A. W., Brugts, J. J., & CHECK-HF Investigators (2020). Treatment Differences in Chronic Heart Failure Patients With Reduced Ejection Fraction According to Blood Pressure. Circulation-Heart Failure, 13(5), Article 006667. https://doi.org/10.1161/circheartfailure.119.006667
    • Cannata, A., De Angelis, G., Boscutti, A., Normand, C., Artico, J., Gentile, P., Zecchin, M., Heymans, S., Merlo, M., & Sinagra, G. (2020). Arrhythmic risk stratification in non-ischaemic dilated cardiomyopathy beyond ejection fraction. Heart, 106(9), 656-664. https://doi.org/10.1136/heartjnl-2019-315942
    • Seferovic, P. M., Piepoli, M. F., Lopatin, Y., Jankowska, E., Polovina, M., Anguita-Sanchez, M., Stoerk, S., Lainscak, M., Milicic, D., Milinkovic, I., Filippatos, G., Coats, A. J. S., Anker, S., Backs, J., Bauersachs, J., Ben Gal, T., de Boer, R. A., Doehner, W., Celutkiene, J., ... Heart Failure Association Board of the European Society of Cardiology (2020). Heart Failure Association of the European Society of Cardiology Quality of Care Centres Programme: design and accreditation document. European journal of heart failure, 22(5), 763-774. https://doi.org/10.1002/ejhf.1784
    • Stohr, R., Brandenburg, V. M., Heine, G. H., Maeder, M. T., Leibundgut, G., Schuh, A., Jeker, U., Pfisterer, M., Sanders-van Wijk, S., & Brunner-La Rocca, H. P. (2020). Limited role for fibroblast growth factor 23 in assessing prognosis in heart failure patients: data from the TIME-CHF trial. European journal of heart failure, 22(4), 701-709. https://doi.org/10.1002/ejhf.1749
    • Brunner-La Rocca, H. P. (2020). What do we need to better understand the role of biomarkers in heart failure?International Journal of Cardiology, 304, 93-94. https://doi.org/10.1016/j.ijcard.2020.01.018
    • Vrolijk, M. F., van Essen, H., Opperhuizen, A., Bast, A., & Janssen, B. J. (2020). Haemodynamic effects of the flavonoid quercetin in rats revisited. British Journal of Pharmacology, 177(8), 1841-1852. https://doi.org/10.1111/bph.14955
    • Vonhoegen, I. G. C., el Azzouzi, H., Olieslagers, S., Vasilevich, A., de Boer, J., Tinahones, F. J., Martins, P. A. D. C., de Windt, L. J., & Murri, M. (2020). MiR-337-3p Promotes Adipocyte Browning by Inhibiting TWIST1. Cells, 9(4), Article 1056. https://doi.org/10.3390/cells9041056
    • De Bortoli, M., Vio, R., Basso, C., Calore, M., Minervini, G., Angelini, A., Melacini, P., Vitiello, L., Vazza, G., Thiene, G., Tosatto, S., Corrado, D., Iliceto, S., Rampazzo, A., & Calore, C. (2020). Novel Missense Variant in MYL2 Gene Associated With Hypertrophic Cardiomyopathy Showing High Incidence of Restrictive Physiology. Circulation: Genomic and Precision Medicine, 13(2), Article 002824. https://doi.org/10.1161/circgen.119.002824
    • Li, Z. W., Moalin, M., Zhang, M., Vervoort, L., Mommers, A., & Haenen, G. R. M. M. (2020). Delocalization of the Unpaired Electron in the Quercetin Radical: Comparison of Experimental ESR Data with DFT Calculations. International Journal of Molecular Sciences, 21(6), Article 2033. https://doi.org/10.3390/ijms21062033
    • Aizpurua, A. B., Sanders-van Wijk, S., Brunner-La Rocca, H. P., Henkens, M., Heymans, S., Beussink-Nelson, L., Shah, S. J., & van Empel, V. P. M. (2020). Validation of the HFA-PEFF score for the diagnosis of heart failure with preserved ejection fraction. European journal of heart failure, 22(3), 413-421. https://doi.org/10.1002/ejhf.1614
    • Holwerda, A. M., Bouwman, F. G., Nabben, M., Wang, P., van Kranenburg, J., Gijsen, A. P., Burniston, J. G., Mariman, E. C. M., & van Loon, L. J. C. (2020). Endurance-Type Exercise Increases Bulk and Individual Mitochondrial Protein Synthesis Rates in Rats. International Journal of Sport Nutrition and Exercise Metabolism, 30(2), 153-164. https://doi.org/10.1123/ijsnem.2019-0281
    • Verdonschot, J. A. J., Wang, P., Van Bilsen, M., Hazebroek, M. R., Merken, J. J., Vanhoutte, E. K., Henkens, M. T. H. M., Van Den Wijngaard, A., Glatz, J. F. C., Krapels, I. P. C., Brunner, H. G., Heymans, S. R. B., & Bierau, J. (2020). Metabolic Profiling Associates with Disease Severity in Nonischemic Dilated Cardiomyopathy. Journal of Cardiac Failure, 26(3), 212-222. https://doi.org/10.1016/j.cardfail.2019.09.004
    • Peters, M. M. C., Sampaio-Pinto, V., & da Costa Martins, P. A. (2020). Non-coding RNAs in endothelial cell signalling and hypoxia during cardiac regeneration. Biochimica et Biophysica Acta-Molecular Cell Research, 1867(3), Article 118515. https://doi.org/10.1016/j.bbamcr.2019.07.010
    • Vangrieken, P., Al-Nasiry, S., Bast, A., Leermakers, P. A., Tulen, C. B. M., Janssen, G. M. J., Schiffers, P. M. H., van Schooten, F. J., & Remels, A. H. V. (2020). Placental Mitochondrial Abnormalities Upon Hypoxia; The Cause of Placental Oxidative Stress?Reproductive Sciences, 27(SUPPL 1), 268A-268A.
    • Stienen, S., Ferreira, J. P., Kobayashi, M., Preud'homme, G., Dobre, D., Machu, J.-L., Duarte, K., Bresso, E., Devignes, M.-D., Lopez, N., Girerd, N., Aakhus, S., Ambrosio, G., Brunner-La Rocca, H.-P., Fontes-Carvalho, R., Fraser, A. G., Van Heerebeek, L., Heymans, S., De Keulenaer, G., ... Rossignol, P. (2020). Enhanced clinical phenotyping by mechanistic bioprofiling in heart failure with preserved ejection fraction: insights from the MEDIA-DHF study (The Metabolic Road to Diastolic Heart Failure). Biomarkers, 25(2), 201-211. https://doi.org/10.1080/1354750X.2020.1727015
    • Verdonschot, J. A. J., Robinson, E. L., James, K. N., Mohamed, M. W., Claes, G. R. F., Casas, K., Vanhoutte, E. K., Hazebroek, M. R., Kringlen, G., Pasierb, M. M., van den Wijngaard, A., Glatz, J. F. C., Heymans, S. R. B., Krapels, I. P. C., Nahas, S., Brunner, H. G., & Szklarczyk, R. (2020). Mutations in PDLIM5 are rare in dilated cardiomyopathy but are emerging as potential disease modifiers. Molecular genetics & genomic medicine, 8(2), Article e1049. https://doi.org/10.1002/mgg3.1049
    • Barutaut, M., Fournier, P., Peacock, W. F., Evaristi, M. F., Caubere, C., Turkieh, A., Desmoulin, F., Eurlings, L. W. M., van Wijk, S., Brunner-La Rocca, H.-P., Butler, J., Koukoui, F., Dambrin, C., Mazeres, S., Le Page, S., Delmas, C., Galinier, M., Jung, C., Smih, F., & Rouet, P. (2020). Insulin-like Growth Factor Binding Protein 2 predicts mortality risk in heart failure. International Journal of Cardiology, 300, 245-251. https://doi.org/10.1016/j.ijcard.2019.09.032
    • Blankesteijn, W. M. (2020). Interventions in WNT Signaling to Induce Cardiomyocyte Proliferation: Crosstalk with Other Pathways. Molecular Pharmacology, 97(2), 90-101. https://doi.org/10.1124/mol.119.118018
    • Wang, S., Wong, L.-Y., Neumann, D., Liu, Y., Sun, A., Antoons, G., Strzelecka, A., Glatz, J. F. C., Nabben, M., & Luiken, J. J. F. P. (2020). Augmenting Vacuolar H+-ATPase Function Prevents Cardiomyocytes from Lipid-Overload Induced Dysfunction. International journal of molecular sciences, 21(4), Article 1520. https://doi.org/10.3390/ijms21041520
    • Koetsier, E., Franken, G., Debets, J., van Kuijk, S. M. J., Linderoth, B., Joosten, E. A., & Maino, P. (2020). Dorsal Root Ganglion Stimulation in Experimental Painful Diabetic Polyneuropathy: Delayed Wash-Out of Pain Relief After Low-Frequency (1Hz) Stimulation. Neuromodulation, 23(2), 177-184. https://doi.org/10.1111/ner.13048
    • Franken, G., Debets, J., & Joosten, E. A. J. (2020). Nonlinear Relation Between Burst Dorsal Root Ganglion Stimulation Amplitude and Behavioral Outcome in an Experimental Model of Painful Diabetic Peripheral Neuropathy. Neuromodulation, 23(2), 158-166. https://doi.org/10.1111/ner.13070
    • Verdonschot, J. A. J., Merken, J. J., Brunner-La Rocca, H.-P., Hazebroek, M. R., Eurlings, C. G. M. J., Thijssen, E., Wang, P., Weerts, J., van Empel, V., Schummers, G., Schreckenberg, M., van den Wijngaard, A., Lumens, J., Brunner, H. G., Heymans, S. R. B., Krapels, I. P. C., & Knackstedt, C. (2020). Value of Speckle Tracking-Based Deformation Analysis in Screening Relatives of Patients With Asymptomatic Dilated Cardiomyopathy. JACC-Cardiovascular Imaging, 13(2), 549-558. https://doi.org/10.1016/j.jcmg.2019.02.032
    • Gomes, C. P. C., Schroen, B., Kuster, G. M., Robinson, E. L., Ford, K., Squire, I. B., Heymans, S., Martelli, F., Emanueli, C., Devaux, Y., & EU-CardioRNA COST Action (CA17129) (2020). Regulatory RNAs in Heart Failure. Circulation, 141(4), 313-328. https://doi.org/10.1161/CIRCULATIONAHA.119.042474
    • Azodi, M., Kamps, R., Heymans, S., & Robinson, E. L. (2020). The Missing "lnc" between Genetics and Cardiac Disease. Non-coding RNA, 6(1), Article 3. https://doi.org/10.3390/ncrna6010003
    • Giamouridis, D., Gao, M. H., Lai, N. C., Guo, T., Miyanohara, A., Blankesteijn, W. M., Biessen, E. A. L., & Hammond, H. K. (2020). Urocortin 2 Gene Transfer Improves Heart Function in Aged Mice. Molecular Therapy, 28(1), 180-188. https://doi.org/10.1016/j.ymthe.2019.10.003
    • Bertero, E., Sequeira, V., Heymans, S., & Maack, C. (2020). Response to 'The possible role of insulin and glucagon in patients with heart failure and Type 2 diabetes'. European Heart Journal, 41(2), 326-327. https://doi.org/10.1093/eurheartj/ehz243
    • Brugts, J. J., Veenis, J. F., Radhoe, S. P., Linssen, G. C. M., van Gent, M., Borleffs, C. J. W., van Ramshorst, J., van Pol, P., Tukkie, R., Spee, R. F., Emans, M. E., Kok, W., van Halm, V. P., Handoko, L., Beeres, S. L. M. A., Post, M. C., Boersma, E., Lenzen, M. J., Manintveld, C., ... de Boer, R. A. (2020). A randomised comparison of the effect of haemodynamic monitoring with CardioMEMS in addition to standard care on quality of life and hospitalisations in patients with chronic heart failure: Design and rationale of the MONITOR HF multicentre randomised clinical trial. Netherlands Heart Journal, 28(1), 16-26. https://doi.org/10.1007/s12471-019-01341-9
    • Glatz, J. F. C., Luiken, J. J. F. P., & Nabben, M. (2020). CD36 (SR-B2) as a Target to Treat Lipid Overload-Induced Cardiac Dysfunction. Journal of lipid and atherosclerosis, 9(1), 66-78. https://doi.org/10.12997/jla.2020.9.1.66
    • Simmonds, S. J., Cuijpers, I., Heymans, S., & Jones, E. A. V. (2020). Cellular and Molecular Differences between HFpEF and HFrEF: A Step Ahead in an Improved Pathological Understanding. Cells, 9(1), Article 242. https://doi.org/10.3390/cells9010242
    • Koetsier, E., Franken, G., Debets, J., Heijmans, L., van Kuijk, S. M. J., Linderoth, B., Joosten, E. A., & Maino, P. (2020). Mechanism of dorsal root ganglion stimulation for pain relief in painful diabetic polyneuropathy is not dependent on GABA release in the dorsal horn of the spinal cord. CNS Neuroscience & Therapeutics, 26(1), 136-143. https://doi.org/10.1111/cns.13192
    • Ferreira, J. P., Pizard, A., Machu, J.-L., Bresso, E., Brunner-La Rocca, H.-P., Girerd, N., Leroy, C., Gonzalez, A., Diez, J., Heymans, S., Devignes, M.-D., Rossignol, P., Zannad, F., & FIBRO-TARGETS investigators (2020). Plasma protein biomarkers and their association with mutually exclusive cardiovascular phenotypes: the FIBRO-TARGETS case-control analyses. Clinical research in cardiology, 109(1), 22-33. https://doi.org/10.1007/s00392-019-01480-4
    • Leeuwis, A. E., Hooghiemstra, A. M., Bron, E. E., Kuipers, S., Oudeman, E. A., Kalay, T., Brunner-La Rocca, H.-P., Kappelle, L. J., van Oostenbrugge, R. J., Greving, J. P., Niessen, W. J., van Buchem, M. A., van Osch, M. J. P., van Rossum, A. C., Prins, N. D., Biessels, G.-J., Barkhof, F., van der Flier, W. M., & Heart-Brain Connection Consortium (2020). Cerebral blood flow and cognitive functioning in patients with disorders along the heart-brain axis: Cerebral blood flow and the heart-brain axis. Alzheimer's and Dementia: Translational Research and Clinical Interventions, 6(1), Article e12034. https://doi.org/10.1002/trc2.12034
    • van Loon, T., Knackstedt, C., Cornelussen, R., Reesink, K., Brunner-La Rocca, H., Delhaas, T., van Empel, V., & Lumens, J. (2020). Increased myocardial stiffness more than impaired relaxation function limits cardiac performance during exercise in heart failure with preserved ejection fraction: a virtual patient study. European Heart Journal - Digital Health, 1(1), 40-50. https://doi.org/10.1093/ehjdh/ztaa009
    • Glatz, J., Luiken, J., & Nabben, M. (2020). Metabolic Modulation to Treat Cardiac Diseases: Role for Membrane Substrate Transporters. Journal of Cardiology and Cardiovascular Sciences, 4(1), 24-29. https://doi.org/10.29245/2578-3025/2020/1.1187