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Omerovic, E., Citro, R., Bossone, E., Redfors, B., Backs, J., Bruns, B., Ciccarelli, M., Couch, L. S., Dawson, D., Grassi, G., Iacoviello, M., Parodi, G., Schneider, B., Templin, C., Ghadri, J. R., Thum, T., Chioncel, O., Tocchetti, C. G., Van Der Velden, J., ... Lyon, A. R. (2022). Pathophysiology of Takotsubo Syndrome - a joint scientific statement from the Heart Failure Association Takotsubo Syndrome Study Group and Myocardial Function Working Group of the European Society of Cardiology - Part 1: Overview and the central role for catecholamines and sympathetic nervous system. European journal of heart failure, 24(2), 257-273. https://doi.org/10.1002/ejhf.2400

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Weerts, J., Barandiarán Aizpurua, A., Henkens, M. T. H. M., Lyon, A., van Mourik, M. J. W., van Gemert, M. R. A. A., Raafs, A., Sanders-van Wijk, S., Bayés-Genís, A., Heymans, S. R. B., Crijns, H. J. G. M., Brunner-La Rocca, H.-P., Lumens, J., van Empel, V. P. M., & Knackstedt, C. (2022). The prognostic impact of mechanical atrial dysfunction and atrial fibrillation in heart failure with preserved ejection fraction. European Heart Journal Cardiovascular Imaging, 23(1), 74-84. https://doi.org/10.1093/ehjci/jeab222

Gadde, S. G. K., Kshirsagar, A., Anegondi, N., Mochi, T. B., Heymans, S., Ghosh, A., & Roy, A. S. (2021). Correlation of Volume of Macular Edema with Retinal Tomography Features in Diabetic Retinopathy Eyes. Journal of Personalized Medicine, 11(12), Article 1337. https://doi.org/10.3390/jpm11121337

Ferreira, J. P., Girerd, N., Brunner-La Rocca, H. P., Pellicori, P., Cleland, J. G., Rossignol, P., & Zannad, F. (2021). No influence of spironolactone on plasma concentrations of angiotensin-converting enzyme 2: Findings from the HOMAGE randomized trial. Archives of Cardiovascular Diseases, 114(12), 814-817. https://doi.org/10.1016/j.acvd.2021.10.003

Scherrenberg, M., Storms, V., van der Velde, A. E., Boyne, J., Bruins, W., Vranken, J., Leenen, J. P. L., Brunner-La Rocca, H.-P., De Kluiver, E. P., & Dendale, P. (2021). A Home Hospitalisation Strategy for Patients with an Acute Episode of Heart Failure Using a Digital Health-Supported Platform: A Multicentre Feasibility Study - A Rationale and Study Design. Cardiology, 146(6), 793-800. https://doi.org/10.1159/000519085

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Gandhi, S., Witten, A., De Majo, F., Gilbers, M., Maessen, J., Schotten, U., de Windt, L. J., & Stoll, M. (2021). Evolutionarily conserved transcriptional landscape of the heart defining the chamber specific physiology. Genomics, 113(6), 3782-3792. https://doi.org/10.1016/j.ygeno.2021.09.002

Ciccarelli, M., Dawson, D., Falcao-Pires, I., Giacca, M., Hamdani, N., Heymans, S., Hooghiemstra, A., Leeuwis, A., Hermkens, D., Tocchetti, C. G., van der Velden, J., Zacchigna, S., & Thum, T. (2021). Reciprocal organ interactions during heart failure: a position paper from the ESC Working Group on Myocardial Function. Cardiovascular Research, 117(12), 2416-2433. https://doi.org/10.1093/cvr/cvab009

Wang, S. J., Schianchi, F., Neumann, D., Wong, L. Y., Sun, A. M., van Nieuwenhoven, F. A., Zeegers, M. P., Strzelecka, A., Col, U., Glatz, J. F. C., Nabben, M., & Luiken, J. J. F. P. (2021). Specific amino acid supplementation rescues the heart from lipid overload-induced insulin resistance and contractile dysfunction by targeting the endosomal mTOR-v-ATPase axis. Molecular Metabolism, 53, Article 101293. https://doi.org/10.1016/j.molmet.2021.101293

Stroeks, S. L. V. M., Hellebrekers, D. M. E. I., Claes, G. R. F., Tayal, U., Krapels, I. P. C., Vanhoutte, E. K., van den Wijngaard, A., Henkens, M. T. H. M., Ware, J. S., Heymans, S. R. B., Brunner, H. G., & Verdonschot, J. A. J. (2021). Clinical impact of re-evaluating genes and variants implicated in dilated cardiomyopathy. Genetics in Medicine, 23(11), 2186-2193. https://doi.org/10.1038/s41436-021-01255-1

Remmelzwaal, S., Beulens, J. W. J., Elders, P. J. M., Stehouwer, C. D. A., Handoko, M. L., Appelman, Y., van Empel, V., Heymans, S. R. B., & van Ballegooijen, A. J. (2021). Sex-specific associations of body composition measures with cardiac function and structure after 8 years of follow-up. Scientific Reports, 11(1), Article 21046. https://doi.org/10.1038/s41598-021-00541-x

Anker, S. D., Butler, J., Filippatos, G., Ferreira, J. P., Bocchi, E., Bohm, M., Brunner-La Rocca, H. P., Choi, D. J., Chopra, V., Chuquiure-Valenzuela, E., Giannetti, N., Gomez-Mesa, J. E., Janssens, S., Januzzi, J. L., Gonzalez-Juanatey, J. R., Merkely, B., Nicholls, S. J., Perrone, S. V., Pina, I. L., ... EMPEROR-Preserved Trial Investigators (2021). Empagliflozin in Heart Failure with a Preserved Ejection Fraction. New England Journal of Medicine, 385(16), 1451-1461. https://doi.org/10.1056/NEJMoa2107038

Sacchetto, C., Mohseni, Z., Colpaert, R. M. W., Vitiello, L., De Bortoli, M., Vonhogen, I. G. C., Xiao, K., Poloni, G., Lorenzon, A., Romualdi, C., Bariani, R., Mazzotti, E., Daliento, L., Bauce, B., Corrado, D., Thum, T., Rampazzo, A., de Windt, L. J., & Calore, M. (2021). Circulating miR-185-5p as a Potential Biomarker for Arrhythmogenic Right Ventricular Cardiomyopathy. Cells, 10(10), Article 2578. https://doi.org/10.3390/cells10102578

Schreurs, J., Sacchetto, C., Colpaert, R. M. W., Vitiello, L., Rampazzo, A., & Calore, M. (2021). Recent Advances in CRISPR/Cas9-Based Genome Editing Tools for Cardiac Diseases. International Journal of Molecular Sciences, 22(20), Article 10985. https://doi.org/10.3390/ijms222010985

Verdonschot, J. A. J., Henkens, M. T. H. M., Wang, P., Schummers, G., Raafs, A. G., Krapels, I. P. C., van Empel, V., Heymans, S. R. B., Brunner-La Rocca, H.-P., & Knackstedt, C. (2021). A global longitudinal strain cut-off value to predict adverse outcomes in individuals with a normal ejection fraction. Esc heart failure, 8(5), 4343-4345. https://doi.org/10.1002/ehf2.13465

Raafs, A., Verdonschot, J., Ferreira, J. P., Wang, P., Collier, T., Henkens, M., Bjorkman, J., Boccanelli, A., Clark, A. L., Delles, C., Diez, J., Gonzalez, A., Girerd, N., Jukema, J. W., Pinet, F., Rossignol, P., Thum, T., Vodovar, N., de Boer, R. A., ... Heymans, S. (2021). Identification of sex-specific biomarkers predicting new-onset heart failure. Esc heart failure, 8(5), 3512-3520. https://doi.org/10.1002/ehf2.13476

Moura, B., Aimo, A., Al-Mohammad, A., Flammer, A., Barberis, V., Bayes-Genis, A., Brunner-La Rocca, H. P., Fontes-Carvalho, R., Grapsa, J., Hulsmann, M., Ibrahim, N., Knackstedt, C., Januzzi, J. L., Lapinskas, T., Sarrias, A., Matskeplishvili, S., Meijers, W. C., Messroghli, D., Mueller, C., ... Richards, A. M. (2021). Integration of imaging and circulating biomarkers in heart failure: a consensus document by the Biomarkers and Imaging Study Groups of the Heart Failure Association of the European Society of Cardiology. European journal of heart failure, 23(10), 1577-1596. https://doi.org/10.1002/ejhf.2339

McDonagh, T. A., Metra, M., Adamo, M., Gardner, R. S., Baumbach, A., Bohm, M., Burri, H., Butler, J., Celutkiene, J., Chioncel, O., Cleland, J. G. F., Coats, A. J. S., Crespo-Leiro, M. G., Farmakis, D., Gilard, M., Heymans, S., Hoes, A. W., Jaarsma, T., Jankowska, E. A., ... ESC Scientific Document Group (2021). 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure. European Heart Journal, 42(36), 3599-3726. https://doi.org/10.1093/eurheartj/ehab368

Jedrzejczyk, M. A., Van den Bosch, S., Van Aelst, J., Van Aelst, K., Kouris, P. D., Moalin, M., Haenen, G. R. M. M., Boot, M. D., Hensen, E. J. M., Lagrain, B., Sels, B. F., & Bernaerts, K. V. (2021). Lignin-Based Additives for Improved Thermo-Oxidative Stability of Biolubricants. ACS Sustainable Chemistry & Engineering, 9(37), 12548-12559. https://doi.org/10.1021/acssuschemeng.1c02799

De Majo, F., Martens, L., Hegenbarth, J. C., Ruhle, F., Hamczyk, M. R., Nevado, R. M., Andres, V., Hilbold, E., Bar, C., Thum, T., de Boer, M., Duncker, D. J., Schroen, B., Armand, A. S., Stoll, M., & De Windt, L. J. (2021). Genomic instability in the naturally and prematurely aged myocardium. Proceedings of the National Academy of Sciences of the United States of America, 118(36), Article e2022974118. https://doi.org/10.1073/pnas.2022974118

Vergaro, G., Gentile, F., Meems, L. M. G., Aimo, A., Januzzi, J. L., Richards, A. M., Lam, C. S. P., Latini, R., Staszewsky, L., Anand, I. S., Cohn, J. N., Ueland, T., Gullestad, L., Aukrust, P., Brunner-La Rocca, H. P., Bayes-Genis, A., Lupon, J., Yoshihisa, A., Takeishi, Y., ... Emdin, M. (2021). NT-proBNP for Risk Prediction in Heart Failure: Identification of Optimal Cutoffs Across Body Mass Index Categories. JACC: Heart Failure, 9(9), 653-663. https://doi.org/10.1016/j.jchf.2021.05.014

Amin, H., Weerts, J., Brunner-La Rocca, H. P., Knackstedt, C., & Sanders-van Wijk, S. (2021). Future perspective of heart failure care: benefits and bottlenecks of artificial intelligence and eHealth. Future Cardiology, 17(6), 917-921. https://doi.org/10.2217/fca-2021-0008

Veenis, E. F., Brunner-La Rocca, H. P., Linssen, G. C. M., Erol-Yilmaz, A., Pronk, A. C. B., Engelen, D. J. M., van Tooren, R. M., Koornstra-Wortel, H. J. J., de Boer, R. A., van der Meer, P., Hoes, A. W., Brugts, J. J., & CHECK-HF Investigators (2021). Impact of sex-specific target dose in chronic heart failure patients with reduced ejection fraction. European Journal of Preventive Cardiology, 28(9), 957-965. Article 2047487320923185. https://doi.org/10.1177/2047487320923185

van Gorp, R. H., Baaten, C. C. F. M. J., Habibi, A., Jaminon, A. M. G., Peeters, F. E. C. M., Leenders, P., Crijns, H. J. G. M. C., Heemskerk, J. W. M., Reutelingsperger, C. P., Spronk, H. M., & Schurgers, L. J. (2021). Vitamin K antagonist use induces calcification and atherosclerotic plaque progression resulting in increased hypercoagulability. European heart journal open, 1(2), Article oeab017. https://doi.org/10.1093/ehjopen/oeab017

Raso, A., Dirkx, E., Sampaio-Pinto, V., el Azzouzi, H., Cubero, R. J., Sorensen, D. W., Ottaviani, L., Olieslagers, S., Huibers, M. M., de Weger, R., Siddiqi, S., Moimas, S., Torrini, C., Zentillin, L., Braga, L., Nascimento, D. S., da Costa Martins, P. A., van Berlo, J. H., Zacchigna, S., ... De Windt, L. J. (2021). A microRNA program regulates the balance between cardiomyocyte hyperplasia and hypertrophy and stimulates cardiac regeneration. Nature Communications, 12(1), Article 4808. https://doi.org/10.1038/s41467-021-25211-4

Verdonschot, J. A. J., Ferreira, J. P., Pellicori, P., Brunner-La Rocca, H. P., Clark, A. L., Cosmi, F., Cuthbert, J., Girerd, N., Mariottoni, B., Petutschnigg, J., Rossignol, P., Cleland, J. G. F., Zannad, F., Heymans, S. R. B., & HOMAGE “Heart Omics in AGEing” consortium (2021). Proteomic mechanistic profile of patients with diabetes at risk of developing heart failure: insights from the HOMAGE trial. Cardiovascular Diabetology, 20(1), Article 163. https://doi.org/10.1186/s12933-021-01357-9

Russcher, A., Verdonschot, J., Molenaar-de Backer, M. W. A., Heymans, S. R. B., Kroes, A. C. M., & Zaaijer, H. L. (2021). Parvovirus B19 DNA detectable in hearts of patients with dilated cardiomyopathy, but absent or inactive in blood. Esc heart failure, 8(4), 2723-2730. https://doi.org/10.1002/ehf2.13341

Abreu, R. C., Ramos, C., Becher, C., Lino, M., Jesus, C., da Costa Martins, P. A., Martins, P. A. T., Moreno, M. J., Fernandes, H., & Ferreira, L. (2021). Exogenous loading of miRNAs into small extracellular vesicles. Journal of Extracellular Vesicles, 10(10), Article 12111. https://doi.org/10.1002/jev2.12111

Simonavicius, J., Maeder, M. T., Eurlings, C. G. M. J., Aizpurua, A. B., Celutkiene, J., Barysiene, J., Toggweiler, S., Kaufmann, B. A., & Brunner-La Rocca, H.-P. (2021). Intensification of pharmacological decongestion but not the actual daily loop diuretic dose predicts worse chronic heart failure outcome: insights from TIME-CHF. Clinical research in cardiology, 110(8), 1221-1233. https://doi.org/10.1007/s00392-020-01779-7

Vangrieken, P., Al-Nasiry, S., Bast, A., Leermakers, P. A., Tulen, C. B. M., Schiffers, P. M. H., van Schooten, F. J., & Remels, A. H. V. (2021). Placental Mitochondrial Abnormalities in Preeclampsia. Reproductive Sciences, 28(8), 2186-2199. https://doi.org/10.1007/s43032-021-00464-y

Marcks, N., Aimo, A., Januzzi, J. L., Vergaro, G., Clerico, A., Latini, R., Meessen, J., Anand, I. S., Cohn, J. N., Gravning, J., Ueland, T., Bayes-Genis, A., Lupón, J., de Boer, R. A., Yoshihisa, A., Takeishi, Y., Egstrup, M., Gustafsson, I., Gaggin, H. K., ... Brunner-La Rocca, H.-P. (2021). Re-appraisal of the obesity paradox in heart failure: a meta-analysis of individual data. Clinical research in cardiology, 110(8), 1280-1291. https://doi.org/10.1007/s00392-021-01822-1

Veugen, M. G. J., Linssen, P. B. C., Henry, R. M. A., Koster, A., Kroon, A. A., Stehouwer, C. D. A., & Brunner-La Rocca, H.-P. (2021). Measures of Left Ventricular Diastolic Function and Cardiorespiratory Fitness According to Glucose Metabolism Status: The Maastricht Study. Journal of the American Heart Association, 10(13), Article 020387. https://doi.org/10.1161/jaha.120.020387

Breuls, N., Giarratana, N., Yedigaryan, L., Garrido, G. M., Carai, P., Heymans, S., Ranga, A., Deroose, C., & Sampaolesi, M. (2021). Valproic acid stimulates myogenesis in pluripotent stem cell-derived mesodermal progenitors in a NOTCH-dependent manner. Cell Death & Disease, 12(7), Article 677. https://doi.org/10.1038/s41419-021-03936-w

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