• 2010
    • Dennert, R. M., van Paassen, P., Schalla, S., Kuznetsova, T., Alzand, B. S. N., Staessen, J. A., Velthuis, S., Crijns, H. J., Tervaert, J. W. C., & Heymans, S. (2010). Cardiac Involvement in Churg-Strauss Syndrome. Arthritis & Rheumatism, 62(2), 627-634. https://doi.org/10.1002/art.27263
    • van Rooij, E., Fielitz, J., Sutherland, L. B., Thijssen, V. L., Crijns, H. J., Dimaio, M. J., Shelton, J., De Windt, L. J., Hill, J. A., & Olson, E. N. (2010). Myocyte Enhancer Factor 2 and Class II Histone Deacetylases Control a Gender-Specific Pathway of Cardioprotection Mediated by the Estrogen Receptor. Circulation Research, 106(1), 155-U315. https://doi.org/10.1161/CIRCRESAHA.109.207084
    • Lenaers, E., Feyter, H. M., Hoeks, J., Schrauwen, P., Schaart, G., Nabben, M., Nicolay, K., Prompers, J. J., & Hesselink, M. K. (2010). Adaptations in mitochondrial function parallel, but fail to rescue, the transition to severe hyperglycemia and hyperinsulinemia: a study in Zucker diabetic fatty rats.Obesity, 18(6), 1100-1107. https://doi.org/10.1038/oby.2009.372
    • Jacobs, H., Moalin, M., Bast, A., van der Vijgh, W. J., & Haenen, G. R. M. M. (2010). An essential difference between the flavonoids monoHER and quercetin in their interplay with the endogenous antioxidant network. PLOS ONE, 5(11), Article e13880. https://doi.org/10.1371/journal.pone.0013880
    • Bartholomé, R., Haenen, G. R. M. M., Hollman, C. H., Bast, A., Dagnelie, P. C., Roos, D., Keijer, J., Kroon, P. A., Needs, P. W., & Arts, C. W. (2010). Deconjugation Kinetics of Glucuronidated Phase II Flavonoid Metabolites by beta-glucuronidase from Neutrophils. Drug metabolism and pharmacokinetics, 25(4), 379-87. https://doi.org/10.2133/dmpk.DMPK-10-RG-002
    • den Hartog, G. J., Boots, A. W., Adam Perrot, A., Brouns, F. J. P. H., Verkooijen, I. W., Weseler, A. R., Haenen, G. R., & Bast, A. (2010). Erythritol is a sweet antioxidant. Nutrition, 26(4), 449-458. https://doi.org/10.1016/j.nut.2009.05.004
    • Gungor, N., Knaapen, A. M., Munnia, A., Peluso, M., Haenen, G. R., Chiu, R. K., Godschalk, R. W., & van Schooten, F. J. (2010). Genotoxic effects of neutrophils and hypochlorous acid. Mutagenesis, 25(2), 149-154. https://doi.org/10.1093/mutage/gep053
    • Bast, A., Weseler, A. R., Haenen, G. R. M. M., & den Hartog, G. J. M. (2010). Oxidative stress and antioxidants in interstitial lung disease.Current Opinion in Pulmonary Medicine, 16(5), 516-520. https://doi.org/10.1097/MCP.0b013e32833c645d
    • Wijnen, P. A., Linssen, C. F., Haenen, G. R., Bekers, O., & Drent, M. (2010). Variant VKORC1 and CYP2C9 Alleles in Patients with Diffuse Alveolar Hemorrhage Caused by Oral Anticoagulants. Molecular Diagnosis & Therapy, 14(1), 23-30. https://doi.org/10.1007/BF03256350
    • Anson, N. M., Havenaar, R., Bast, A., & Haenen, G. R. M. M. (2010). Antioxidant and anti-inflammatory capacity of bioaccessible compounds from wheat fractions after gastrointestinal digestion. Journal of Cereal Science, 51(1), 110-114. https://doi.org/10.1016/j.jcs.2009.10.005
    • PROTECT Steering Committee, & Heymans, S. (2010). Design and Rationale of the PROTECT Study: A Placebo-controlled Randomized Study of the Selective A1 Adenosine Receptor Antagonist Rolofylline for Patients Hospitalized With Acute Decompensated Heart Failure and Volume Overload to Assess Treatment Effect on Congestion and Renal Function. Journal of Cardiac Failure, 16(1), 25-35. https://doi.org/10.1016/j.cardfail.2009.10.025
    • el Azzouzi, H., van Oort, R. J., van der Nagel, R., Sluiter, W., Bergmann, M. W., & De Windt, L. J. (2010). MEF2 transcriptional activity maintains mitochondrial adaptation in cardiac pressure overload. European journal of heart failure, 12(1), 4-12. https://doi.org/10.1093/eurjhf/hfp165
    • van den Borne, S. W. M., Diez, J., Blankesteijn, W. M., Verjans, J., Hofstra, L., & Narula, J. (2010). Myocardial remodeling after infarction: the role of myofibroblasts. Nature Reviews Cardiology, 7(1), 30-37. https://doi.org/10.1038/nrcardio.2009.199
    • Dennert, R., Velthuis, S., Schalla, S., Eurlings, L. W., van Suylen, R.-J., van Paassen, P., Tervaert, J. W. C., Wolffs, P., Goossens, V. J., Bruggeman, C., Waltenberger, J., Crijns, H. J., & Heymans, S. (2010). Intravenous immunoglobulin therapy for patients with idiopathic cardiomyopathy and endomyocardial biopsy-proven high PVB19 viral load. Antiviral Therapy, 15(2), 193-201. https://doi.org/10.3851/IMP1516
    • Megens, R. T. A., Reitsma, S., Prinzen, L., Egbrink, M. G. A. O., Engels, W., Leenders, P. J. A., Brunenberg, E. J. L., Reesink, K. D., Janssen, B. J. A., Romeny, B. M. T. H., Slaaf, D. W., & van Zandvoort, M. A. M. J. (2010). In vivo high-resolution structural imaging of large arteries in small rodents using two-photon laser scanning microscopy. Journal of Biomedical Optics, 15(1), 10. Article 011108. https://doi.org/10.1117/1.3281672
    • Dennert, R., Velthuis, S., Westermann, D., Donker, D. W., Schalla, S., van Suylen, R.-J., & Heymans, S. (2010). Parvovirus-B19-associated fulminant myocarditis successfully treated with immunosuppressive and antiviral therapy. Antiviral Therapy, 15(4), 681-685. https://doi.org/10.3851/IMP1563
  • 2009
    • de Jongh, R., Dambros, M., Haenen, G. R., den Hartog, G. J., Bast, A., van Kerrebroeck, P. E., & van Koeveringe, G. A. (2009). Partial bladder outlet obstruction reduces the tissue antioxidant capacity and muscle nerve density of the guinea pig bladder. Neurourology and Urodynamics, 28(5), 461-467. https://doi.org/10.1002/nau.20677
    • Boots, A. W., Drent, M., Swennen, E. L., Moonen, H. J., Bast, A., & Haenen, G. R. (2009). Antioxidant status associated with inflammation in sarcoidosis: A potential role for antioxidants. Respiratory Medicine, 103(3), 364-372. https://doi.org/10.1016/j.rmed.2008.10.007
    • Boots, A. W., Hristova-Dijkstra, M. J., Kasahara, D. I., Haenen, G. R., Bast, A., & van der Vliet, A. (2009). ATP-mediated activation of the NADPH oxidase DUOX1 mediates airway epithelial responses to bacterial stimuli.Journal of Biological Chemistry, 284(26), 17858-17867. https://doi.org/10.1074/jbc.M809761200
    • Mateo Anson, N., van den Berg, R., Havenaar, R., Bast, A., & Haenen, G. (2009). Bioavailability of ferulic acid is determined by its bioaccessibility. Journal of Cereal Science, 49(2), 296-300. https://doi.org/10.1016/j.jcs.2008.12.001
    • Mateo Anson, N., Selinheimo, E., Havenaar, R., Aura, A. M., Mattila, I., Lehtinen, P., Bast, A., Poutanen, K., & Haenen, G. R. (2009). Bioprocessing of wheat bran improves in vitro bioaccessibility and colonic metabolism of phenolic compounds.Journal of Agricultural and Food Chemistry, 57(14), 6148-6155. https://doi.org/10.1021/jf900492h
    • Jacobs, H., van der Vijgh, W. J., Koek, G. H., Draaisma, G. J., Moalin, M., van Strijdonck, G. P., Bast, A., & Haenen, G. R. (2009). Characterization of the glutathione conjugate of the semisynthetic flavonoid monoHER. Free Radical Biology and Medicine, 46(12), 1567-1573. https://doi.org/10.1016/j.freeradbiomed.2009.02.031
    • Balk, J. M., Bast, A., & Haenen, G. R. (2009). Evaluation of the accuracy of antioxidant competition assays: incorrect assumptions with major impact.Free Radical Biology and Medicine, 47(2), 135-144. https://doi.org/10.1016/j.freeradbiomed.2009.04.009
  • 2008
    • Mateo Anson, N., van den Berg, R., Havenaar, R., Haenen, G. R., & Bast, A. (2008). Antioxidant and anti-inflammatory potency of different wheat varieties and fractions. Proceedings of the Nutrition Society, 67(OCE1), Article E56. https://doi.org/10.1017/S0029665108006654
    • Mateo Anson, N., van den Berg, R., Havenaar, R., Bast, A., & Haenen, G. R. M. (2008). Ferulic Acid from Aleurone Determines the Antioxidant Potency of Wheat Grain (Triticum aestivum L.). Journal of Agricultural and Food Chemistry, 56(14), 5589-5594. https://doi.org/10.1021/jf800445k
    • Boots, A. W., Haenen, G. R., & Bast, A. (2008). Health effects of quercetin: from antioxidant to nutraceutical.European Journal of Pharmacology, 585(2-3), 325-337. https://doi.org/10.1016/j.ejphar.2008.03.008
    • Boots, A., Wilms, L. C., Swennen, E. L., Kleinjans, J. C., Bast, A., & Haenen, G. R. (2008). In vitro and ex vivo anti-inflammatory activity of quercetin in healthy volunteers. Nutrition, 24(7-8), 703-10. https://doi.org/10.1016/j.nut.2008.03.023
    • de Jongh, R., Haenen, G. R. M. M., van Koeveringe, G. A., Dambros, M., & van Kerrebroeck, P. E. V. (2008). Lipid peroxidation product 4-hydroxynonenal contributes to bladder smooth muscle damage.Urology, 71(5), 974-978. https://doi.org/10.1016/j.urology.2007.11.014
    • Hoeks, J., Briede, J. J., de Vogel, J., Schaart, G., Nabben, M., Kornips, E., Hesselink, M. K., & Schrauwen, P. (2008). Mitochondrial function, content and ROS production in rat skeletal muscle: effect of high-fat feeding. Febs Letters, 582(4), 510-6. https://doi.org/10.1016/j.febslet.2008.01.013
    • Wijnen, P. A. H. M., Drent, M., Nelemans, P. J., Kuijpers, P. M., Koek, G. H., Neef, C. K., Haenen, G. R., & Bekers, O. (2008). Role of cytochrome p450 polymorphisms in the development of pulmonary drug toxicity: a case-control study in the Netherlands. Drug Safety, 31(12), 1125-34. https://doi.org/10.2165/0002018-200831120-00008
    • Rensen, S., Niessen, P. M., van Deursen, J. M., Janssen, B. J., Heijman, E., Hermeling, E., Meens, M. J. P. M. T., Lie, N., Gijbels, M. J., Strijkers, G. J., Doevendans, P. A., Hofker, M. H., de Mey, J. G., & van Eys, G. J. (2008). Smoothelin-B deficiency results in reduced arterial contractility, hypertension, and cardiac hypertrophy in mice. Circulation, 118(8), 828-36. https://doi.org/10.1161/CIRCULATIONAHA.107.743690
    • Nabben, M., Hoeks, J., Briede, J. J., Glatz, J. F., Kornips, E., Hesselink, M. K., & Schrauwen, P. (2008). The effect of UCP3 overexpression on mitochondrial ROS production in skeletal muscle of young versus aged mice. Febs Letters, 582(30), 4147-4152. https://doi.org/10.1016/j.febslet.2008.11.016
  • 2007
    • Donker, D. W., Maessen, J. G., Verheyen, F., Ramaekers, F., Spätjens, R. L. H., Kuijpers, R., Rarnakers, C., Schiffers, P. M. H., Vos, M. A., Crijns, H. J. G. M., & Volders, P. G. A. (2007). Impact of acute and enduring volume overload on mechanotransduction and cytoskeletal integrity of canine left ventricular myocardium. American Journal of Physiology-heart and Circulatory Physiology, 292(5), H2324-H2332. https://doi.org/10.1152/ajpheart.00392.2006
    • Rezk, B. M., van der Vijgh, W. J., Bast, A., & Haenen, G. R. (2007). Alpha-tocopheryl phosphate is a novel apoptotic agent. Frontiers in Bioscience, 12, 2013-2019. https://doi.org/10.2741/2206
    • Haenen, G. R. M. M., & Bast, A. (2007). Antioxidanten overbodig? Prietpraat!Chemisch2Weekblad, 102(18), 26-27.
    • Rietjens, S. J., Beelen, M., Koopman, R., van Loon, L. J., Bast, A., & Haenen, G. R. (2007). A single session of resistance exercise induces oxidative damage in untrained men. Medicine and Science in Sports and Exercise, 39(12), 2145-2151. https://doi.org/10.1249/mss.0b013e318157936d
    • Coleman, M. D., Rimmer, G. S., & Haenen, G. R. (2007). Effects of Lipoic Acid and Dihydrolipoic Acid on Total Erythrocytic Thiols under Conditions of Restricted Glucose in vitro. Basic & Clinical Pharmacology & Toxicology, 100(2), 139-144. https://doi.org/10.1111/j.1742-7843.2006.00025.x
    • Goossens, G. H., Jocken, J. W., Blaak, E. E., Schiffers, P. M., Saris, W. H., & van Baak, M. A. (2007). Endocrine Role of the Renin-Angiotensin System in Human Adipose Tissue and Muscle. Effect of {beta}-Adrenergic Stimulation. Hypertension, 49(3), 542-547. https://doi.org/10.1161/01.HYP.0000256091.55393.92
    • Wilms, L. C., Boots, A. W., de Boer, V. C., Maas, L. M., Pachen, D. M., Gottschalk, R. W., Ketelslegers, H., Godschalk, R. W., Haenen, G. R., van Schooten, F. J., & Kleinjans, J. C. (2007). Impact of multiple genetic polymorphisms on effects of a 4-week blueberry juice intervention on ex vivo induced lymphocytic DNA damage in human volunteers. Carcinogenesis, 28(8), 1800-1806. https://doi.org/10.1093/carcin/bgm145
    • van de Schans, V. A. M., van den Borne, S. W. M., Strzelecka, A. E., Janssen, B. J., van der Velden, J. L., Langen, R. C., Wynshaw Boris, A., Smits, J. F., & Blankesteijn, W. M. (2007). Interruption of Wnt Signaling Attenuates the Onset of Pressure Overload-Induced Cardiac Hypertrophy. Hypertension, 49(3), 473-480. https://doi.org/10.1161/01.HYP.0000255946.55091.24
    • Rietjens, S. J., Bast, A., & Haenen, G. R. (2007). New insights into controversies on the antioxidant potential of the olive oil antioxidant hydroxytyrosol. Journal of Agricultural and Food Chemistry, 55(18), 7609-7614. https://doi.org/10.1021/jf0706934
    • Arts, M. J., Grun, C., Jong, R. L., Voss, H. P., Bast, A., Mueller, M. J., & Haenen, G. R. (2007). Oxidative Degradation of Lipids during Mashing. Journal of Agricultural and Food Chemistry, 55(17), 7010-7014. https://doi.org/10.1021/jf070505+
    • de Jongh, R., Haenen, G. R., van Koeveringe, G. A., Dambros, M., de Mey, J. G., & van Kerrebroeck, P. E. V. A. (2007). Oxidative stress reduces the muscarinic receptor function in the urinary bladder. Neurourology and Urodynamics, 26(2), 302-308. https://doi.org/10.1002/nau.20298
    • Bast, A., Haenen, G. R., Bruynzeel, A. M., & van der Vijgh, W. J. (2007). Protection by flavonoids against anthracycline cardiotoxicity: from chemistry to clinical trials. Cardiovascular Toxicology, 7(2), 154-159. https://doi.org/10.1007/s12012-007-0018-0
    • Bast, A., Kaiserova, H., den Hartog, G. J., Haenen, G. R., & van der Vijgh, W. J. (2007). Protectors against doxorubicin-induced cardiotoxicity: Flavonoids. Cell Biology and Toxicology, 23(1), 39-47. https://doi.org/10.1007/s10565-006-0139-4
    • Rietjens, S. J., Bast, A., Vente, J. D., & Haenen, G. (2007). The olive oil antioxidant hydroxytyrosol efficiently protects against the oxidative stress induced impairment of the NO{middle dot} response of isolated rat aorta. American Journal of Physiology-heart and Circulatory Physiology, 292(4), H1931-H1936. https://doi.org/10.1152/ajpheart.00755.2006
    • Boots, A. W., Li, H., Schins, R. P., Heemskerk, J. W., Bast, A., & Haenen, G. R. (2007). The quercetin paradox. Toxicology and Applied Pharmacology, 222(1), 89-96. https://doi.org/10.1016/j.taap.2007.04.004
  • 2006
    • van Haaften, R. I. M., Schroen, B. L., Janssen, B. J., van Erk, A. A., Debets, J. J., Smeets, H. J., Smits, J. F., van den Wijngaard, A., Pinto, Y. M., & Evelo, C. T. (2006). Biologically relevant effects of mRNA amplification on gene expression profiles. BMC Bioinformatics, 7, 200. https://doi.org/10.1186/1471-2105-7-200
    • Goossens, G. H., Blaak, E. E., Schiffers, P. M., Saris, W. H., & van Baak, M. A. (2006). Effect of short-term ACE inhibitor treatment on peripheral insulin sensitivity in obese insulin-resistant subjects. Diabetologia, 49(12), 3009-3016. https://doi.org/10.1007/s00125-006-0458-2
    • Coleman, M. D., Williams, C., & Haenen, G. R. (2006). Effects of Lipoic Acid and Dihydrolipoic Acid on 4-Aminophenol-Mediated Erythrocytic Toxicity in vitro*. Basic & Clinical Pharmacology & Toxicology, 99(3), 225-229. https://doi.org/10.1111/j.1742-7843.2006.pto_499.x