Wijnen, P. A. H. M., Drent, M., Nelemans, P. J., Kuijpers, P. M., Koek, G. H., Neef, C. K., Haenen, G. R., & Bekers, O. (2008). Role of cytochrome p450 polymorphisms in the development of pulmonary drug toxicity: a case-control study in the Netherlands. Drug Safety, 31(12), 1125-34. https://doi.org/10.2165/0002018-200831120-00008

Rensen, S., Niessen, P. M., van Deursen, J. M., Janssen, B. J., Heijman, E., Hermeling, E., Meens, M. J. P. M. T., Lie, N., Gijbels, M. J., Strijkers, G. J., Doevendans, P. A., Hofker, M. H., de Mey, J. G., & van Eys, G. J. (2008). Smoothelin-B deficiency results in reduced arterial contractility, hypertension, and cardiac hypertrophy in mice. Circulation, 118(8), 828-36. https://doi.org/10.1161/CIRCULATIONAHA.107.743690

Nabben, M., Hoeks, J., Briede, J. J., Glatz, J. F., Kornips, E., Hesselink, M. K., & Schrauwen, P. (2008). The effect of UCP3 overexpression on mitochondrial ROS production in skeletal muscle of young versus aged mice. Febs Letters, 582(30), 4147-4152. https://doi.org/10.1016/j.febslet.2008.11.016

Donker, D. W., Maessen, J. G., Verheyen, F., Ramaekers, F., Spätjens, R. L. H., Kuijpers, R., Rarnakers, C., Schiffers, P. M. H., Vos, M. A., Crijns, H. J. G. M., & Volders, P. G. A. (2007). Impact of acute and enduring volume overload on mechanotransduction and cytoskeletal integrity of canine left ventricular myocardium. American Journal of Physiology-heart and Circulatory Physiology, 292(5), H2324-H2332. https://doi.org/10.1152/ajpheart.00392.2006

Rezk, B. M., van der Vijgh, W. J., Bast, A., & Haenen, G. R. (2007). Alpha-tocopheryl phosphate is a novel apoptotic agent. Frontiers in Bioscience, 12, 2013-2019. https://doi.org/10.2741/2206

Haenen, G. R. M. M., & Bast, A. (2007). Antioxidanten overbodig? Prietpraat!Chemisch2Weekblad, 102(18), 26-27.

Rietjens, S. J., Beelen, M., Koopman, R., van Loon, L. J., Bast, A., & Haenen, G. R. (2007). A single session of resistance exercise induces oxidative damage in untrained men. Medicine and Science in Sports and Exercise, 39(12), 2145-2151. https://doi.org/10.1249/mss.0b013e318157936d

Coleman, M. D., Rimmer, G. S., & Haenen, G. R. (2007). Effects of Lipoic Acid and Dihydrolipoic Acid on Total Erythrocytic Thiols under Conditions of Restricted Glucose in vitro. Basic & Clinical Pharmacology & Toxicology, 100(2), 139-144. https://doi.org/10.1111/j.1742-7843.2006.00025.x

Goossens, G. H., Jocken, J. W., Blaak, E. E., Schiffers, P. M., Saris, W. H., & van Baak, M. A. (2007). Endocrine Role of the Renin-Angiotensin System in Human Adipose Tissue and Muscle. Effect of {beta}-Adrenergic Stimulation. Hypertension, 49(3), 542-547. https://doi.org/10.1161/01.HYP.0000256091.55393.92

Wilms, L. C., Boots, A. W., de Boer, V. C., Maas, L. M., Pachen, D. M., Gottschalk, R. W., Ketelslegers, H., Godschalk, R. W., Haenen, G. R., van Schooten, F. J., & Kleinjans, J. C. (2007). Impact of multiple genetic polymorphisms on effects of a 4-week blueberry juice intervention on ex vivo induced lymphocytic DNA damage in human volunteers. Carcinogenesis, 28(8), 1800-1806. https://doi.org/10.1093/carcin/bgm145

van de Schans, V. A. M., van den Borne, S. W. M., Strzelecka, A. E., Janssen, B. J., van der Velden, J. L., Langen, R. C., Wynshaw Boris, A., Smits, J. F., & Blankesteijn, W. M. (2007). Interruption of Wnt Signaling Attenuates the Onset of Pressure Overload-Induced Cardiac Hypertrophy. Hypertension, 49(3), 473-480. https://doi.org/10.1161/01.HYP.0000255946.55091.24

Rietjens, S. J., Bast, A., & Haenen, G. R. (2007). New insights into controversies on the antioxidant potential of the olive oil antioxidant hydroxytyrosol. Journal of Agricultural and Food Chemistry, 55(18), 7609-7614. https://doi.org/10.1021/jf0706934

Arts, M. J., Grun, C., Jong, R. L., Voss, H. P., Bast, A., Mueller, M. J., & Haenen, G. R. (2007). Oxidative Degradation of Lipids during Mashing. Journal of Agricultural and Food Chemistry, 55(17), 7010-7014. https://doi.org/10.1021/jf070505+

de Jongh, R., Haenen, G. R., van Koeveringe, G. A., Dambros, M., de Mey, J. G., & van Kerrebroeck, P. E. V. A. (2007). Oxidative stress reduces the muscarinic receptor function in the urinary bladder. Neurourology and Urodynamics, 26(2), 302-308. https://doi.org/10.1002/nau.20298

Bast, A., Haenen, G. R., Bruynzeel, A. M., & van der Vijgh, W. J. (2007). Protection by flavonoids against anthracycline cardiotoxicity: from chemistry to clinical trials. Cardiovascular Toxicology, 7(2), 154-159. https://doi.org/10.1007/s12012-007-0018-0

Bast, A., Kaiserova, H., den Hartog, G. J., Haenen, G. R., & van der Vijgh, W. J. (2007). Protectors against doxorubicin-induced cardiotoxicity: Flavonoids. Cell Biology and Toxicology, 23(1), 39-47. https://doi.org/10.1007/s10565-006-0139-4

Rietjens, S. J., Bast, A., Vente, J. D., & Haenen, G. (2007). The olive oil antioxidant hydroxytyrosol efficiently protects against the oxidative stress induced impairment of the NO{middle dot} response of isolated rat aorta. American Journal of Physiology-heart and Circulatory Physiology, 292(4), H1931-H1936. https://doi.org/10.1152/ajpheart.00755.2006

Boots, A. W., Li, H., Schins, R. P., Heemskerk, J. W., Bast, A., & Haenen, G. R. (2007). The quercetin paradox. Toxicology and Applied Pharmacology, 222(1), 89-96. https://doi.org/10.1016/j.taap.2007.04.004

van Haaften, R. I. M., Schroen, B. L., Janssen, B. J., van Erk, A. A., Debets, J. J., Smeets, H. J., Smits, J. F., van den Wijngaard, A., Pinto, Y. M., & Evelo, C. T. (2006). Biologically relevant effects of mRNA amplification on gene expression profiles. BMC Bioinformatics, 7, 200. https://doi.org/10.1186/1471-2105-7-200

Goossens, G. H., Blaak, E. E., Schiffers, P. M., Saris, W. H., & van Baak, M. A. (2006). Effect of short-term ACE inhibitor treatment on peripheral insulin sensitivity in obese insulin-resistant subjects. Diabetologia, 49(12), 3009-3016. https://doi.org/10.1007/s00125-006-0458-2

Coleman, M. D., Williams, C., & Haenen, G. R. (2006). Effects of Lipoic Acid and Dihydrolipoic Acid on 4-Aminophenol-Mediated Erythrocytic Toxicity in vitro*. Basic & Clinical Pharmacology & Toxicology, 99(3), 225-229. https://doi.org/10.1111/j.1742-7843.2006.pto_499.x

Vaisman, N., Haenen, G. R., Zaruk, Y., Verduyn, C., Bindels, J. G., Verlaan, S., & Meijer, E. P. (2006). Enteral feeding enriched with carotenoids normalizes the carotenoid status and reduces oxidative stress in long-term enterally fed patients. Clinical Nutrition, 25(6), 897-905. https://doi.org/10.1016/j.clnu.2006.06.002

van Empel, V. P. M., Bertrand, A. T., van Oort, R. J., van der Nagel, R., Engelen, M. P. K. J., van Rijen, H. V., Doevendans, P. A. F. M., Crijns, H. J. G. M., Ackerman, S. L., Sluiter, W., & de Windt, L. J. (2006). EUK-8, a superoxide dismutase and catalase mimetic, reduces cardiac oxidative stress and ameliorates pressure overload-induced heart failure in the harlequin mouse mutant. Journal of the American College of Cardiology, 48(4), 824-832. https://doi.org/10.1016/j.jacc.2006.02.075

Troost, F. J., Brummer, R. J., Haenen, G. R., Bast, A., van Haaften, R. I. M., Evelo, C. T., & Saris, W. H. (2006). Gene expression in human small intestinal mucosa in vivo is mediated by iron-induced oxidative stress. Physiological genomics, 25(2), 242-249. https://doi.org/10.1152/physiolgenomics.00114.2005

Haenen, G. R., Arts, M. J. T., Bast, A., & Coleman, M. D. (2006). Structure and activity in assessing antioxidant activity in vitro and in vivo. A critical appraisal illustrated with the flavenoids. Environmental Toxicology and Pharmacology, 21, 191-198. https://doi.org/10.1016/j.etap.2005.07.010

Gosker, H. R., Bast, A., Haenen, G. R. M. M., Fischer, M. A. J. G., van der Vusse, G. J., Wouters, E. F. M., & Schols, A. M. W. J. (2005). Altered antioxidant status in peripheral skeletal muscle of patients with COPD. Respiratory Medicine, 99, 118-125. https://doi.org/10.1016/j.rmed.2004.05.018

Fischer, M. A. J. G., Gransier, T. J., Beckers, L. M., Bekers, O., Bast, A., & Haenen, G. R. (2005). Determination of the antioxidant capacity in blood. Clinical Chemistry and Laboratory Medicine, 43(7), 735-740. https://doi.org/10.1515/CCLM.2005.125

Boots, A. W., Bast, A., & Haenen, G. R. (2005). No role of DT-diaphorase (NQO1) in the protection against oxidized quercetin. Febs Letters, 579(3), 677-682. https://doi.org/10.1016/j.febslet.2004.12.044

Boots, A. W., Balk, J. M., Bast, A., & Haenen, G. R. (2005). The reversibility of the glutathionyl-quercetin adduct spreads oxidized quercetin-induced toxicity. Biochemical and Biophysical Research Communications, 338(2), 923-929. https://doi.org/10.1016/j.bbrc.2005.10.031

Keularts, I. M. L. W., Beguin, S., & Hemker, H. C. (2004). Gekalibreerde, geautomatiseerde trombinegeneratiecurve: Een nieuwe klinische functie-/screeningstest voor het integrale stollingssysteem. Nederlands Tijdschrift voor Geneeskunde, 148(47), 2364-. https://www.ntvg.nl/artikelen/nederlandse-vereniging-voor-klinische-chemie-en-laboratoriumgeneeskunde-0/volledig

Arts, M. J. T. J., Dallinga, J. W., Voss, H. P., Haenen, G. R. M. M., & Bast, A. (2004). A new approach to assess the total antioxidant capacity using the TEAC assay. Food Chemistry, 88, 567-570. https://doi.org/10.1016/j.foodchem.2004.02.008

Arts, M. J. T. J., Haenen, G. R., Voss, H. P., & Bast, A. (2004). Antioxidant capacity of reaction products limits the applicability of the Trolox Equivalent Antioxidant Capacity (TEAC) assay. Food and Chemical Toxicology, 42(1), 45-49. https://doi.org/10.1016/j.fct.2003.08.004

den Hartog, G. J. M., Haenen, G. R. M. M., Boven, E., van der Vijgh, W. J. F., & Bast, A. (2004). Lecithinized copper,zinc-superoxide dismutase as a protector against doxorubicin-induced cardiotoxicity in mice. Toxicology and Applied Pharmacology, 194(2), 180-188. https://doi.org/10.1016/j.taap.2003.09.008

Rezk, B. M., Haenen, G. R., van der Vijgh, W. J. F., & Bast, A. (2004). Lipoic acid protects efficiently only against a specific form of peroxynitrite-induced damage. Journal of Biological Chemistry, 279(11), 9693-9697. https://doi.org/10.1074/jbc.M312289200

De Celle, T., Heeringa, P., Strzelecka, A. E., Bast, A., Smits, J. F. M., & Janssen, B. J. A. (2004). Sustained protective effects of 7-monohydroxyethylrutoside in an in vivo model of cardiac ischemia-reperfusion. European Journal of Pharmacology, 494(2-3), 205-212. https://doi.org/10.1016/j.ejphar.2004.05.017

Rezk, B. M., Haenen, G. R., van der Vijgh, W. J. F., & Bast, A. (2004). The extraordinary antioxidant activity of vitamin E phosphate. Biochimica et Biophysica Acta-Molecular and Cell Biology of Lipids, 1683(1-3), 16-21. https://doi.org/10.1016/j.bbalip.2004.03.005

Michels, G., Haenen, G. R., Wätjen, W., Rietjens, S. J., & Bast, A. (2004). The thiol reactivity of the oxidation product of 3,5,7-trihydroxy-4H-chromen-4-one containing flavonoids. Toxicology Letters, 151(1), 105-111. https://doi.org/10.1016/j.toxlet.2004.01.017

Beguin, S., Keularts, I., Al Dieri, R., Bellucci, S., Caen, J., & Hemker, H. C. (2004). Fibrin polymerization is crucial for thrombin generation in platelet-rich plasma in a VWF-GPlb-dependent process, defective in Bernhard-Soulier syndrome. Journal of Thrombosis and Haemostasis, 2(1), 170-176. https://doi.org/10.1111/j.1538-7836.2004.00558.x

Arts, M. J. T. J., Dallinga, J. W., Voss, H. P., Haenen, G. R. M. M., & Bast, A. (2003). A critical appraisal of the use of the antioxidant capacity (TEAC) assay in defining optimal structures. Food Chemistry, 80, 409-414. https://doi.org/10.1016/S0308-8146(02)00468-5

de Kok, T. M. C. M., Zwingman, I., Moonen, E. J. C., Schilderman-Houba, P. A. E. L., Rhijnsburger, E. H., Haenen, G. R. M. M., & Kleinjans, J. C. S. (2003). Analysis of oxidative DNA damage after human dietary supplementation with linoleic acid. Food and Chemical Toxicology, 41(3), 351-358. https://doi.org/10.1016/S0278-6915(02)00237-5

Abou el Hassan, M. A., Kedde, M., Zwiers, U. T., Tourn, E., Haenen, G. R. M. M., Bast, A., & van der Vijgh, W. J. F. (2003). Bioavailability and pharmacokinetics of the cardioprotecting flavonoid 7-monohydroxyethylrutoside in mice. Cancer Chemotherapy and Pharmacology, 52(5), 371-376. https://doi.org/10.1007/s00280-003-0667-z

van Haaften, R. I. M., Haenen, G. R. M. M., Evelo, C. T. A., & Bast, A. (2003). Effect of vitamin E on glutathione-dependent enzymes. Drug Metabolism Reviews, 35(2-3), 215-253. https://doi.org/10.1081/DMR-120024086

van Haaften, R. I. M., Haenen, G. R. M. M., van Bladeren, P. J., Bogaards, J. J., Evelo, C. T. A., & Bast, A. (2003). Inhibition of various glutathione S-transferase isoenzymes by RRR-alpha-tocopherol. Toxicology in Vitro, 17(3), 245-251. https://doi.org/10.1016/S0887-2333(03)00038-9

den Hartog, G. J. M., Boots, A. W., Haenen, G. R. M. M., van der Vijgh, W. J. F., & Bast, A. (2003). Lack of inhibition of endothelial nitric oxide synthase in the isolated rat aorta by doxorubicin. Toxicology in Vitro, 17(2), 165-167. https://doi.org/10.1016/S0887-2333(03)00007-9

Bast, A., & Haenen, G. R. M. M. (2003). Lipoic acid: a multifunctional antioxidant. Biofactors, 17(1-4), 207-213. https://doi.org/10.1002/biof.5520170120

Troost, F. J. J., Saris, W. H. M., Haenen, G. R. M. M., Bast, A., & Brummer, R. J. M. (2003). New method to study oxidative damage and antioxidants in the human small bowel: effects of iron application. American Journal of Physiology-Gastrointestinal and Liver Physiology, 285(2), G354-G359. https://doi.org/10.1152/ajpgi.00422.2002

Hallemeesch, M. M., Janssen, B. J. A., de Jonge, W. J., Soeters, P. B., Lamers, W. H., & Deutz, N. E. P. (2003). NO production by cNOS and iNOS reflects blood pressure changes in LPS-challenged mice. American Journal of Physiology : Endocrinology and Metabolism, 285(4), E871-E875. https://doi.org/10.1152/ajpendo.00004.2002

Boots, A. W., Haenen, G. R. M. M., & Bast, A. (2003). Oxidant metabolism in chronic obstructive pulmonary disease. European Respiratory Journal, 22(suppl 46), 14S-27S. https://doi.org/10.1183/09031936.03.00000403a

de Kort, J., Fischer, M., Haenen, G. R. M. M., Bast, A., & Koek, G. H. (2003). Oxidative stress in patients with active HCV infection compared to healthy volunteers. Journal of Hepatology, 38, 374. https://doi.org/10.1016/S0168-8278(03)80643-8