• 2016
    • Heggermont, W. A., Papageorgiou, A.-P., Heymans, S., & van Bilsen, M. (2016). Metabolic support for the heart: complementary therapy for heart failure?European journal of heart failure, 18(12), 1420-1429. https://doi.org/10.1002/ejhf.678
    • Luiken, J. J. F. P., Chanda, D., Nabben, M., Neumann, D., & Glatz, J. F. C. (2016). Post-translational modifications of CD36 (SR-B2): Implications for regulation of myocellular fatty acid uptake. Biochimica et Biophysica Acta-Molecular Basis of Disease, 1862(12), 2253-2258. https://doi.org/10.1016/j.bbadis.2016.09.004
    • Verdonschot, J., Hazebroek, M., Merken, J., Debing, Y., Dennert, R., Brunner-La Rocca, H., & Heymans, S. (2016). Relevance of cardiac parvovirus B19 in myocarditis and dilated cardiomyopathy: review of the literature. European journal of heart failure, 18(12), 1430-1441. https://doi.org/10.1002/ejhf.665
    • Heymans, S., Eriksson, U., Lehtonen, J., & Cooper, L. T. . J. (2016). The Quest for New Approaches in Myocarditis and Inflammatory Cardiomyopathy. Journal of the American College of Cardiology, 68(21), 2348-2364. https://doi.org/10.1016/j.jacc.2016.09.937
    • Ferreira, J. P., Girerd, N., Pellicori, P., Duarte, K., Girerd, S., Pfeffer, M. A., McMurray, J. J. V., Pitt, B., Dickstein, K., Jacobs, L., Staessen, J. A., Butler, J., Latini, R., Masson, S., Mebazaa, A., Brunner-La Rocca, H., Delles, C., Heymans, S., Sattar, N., ... Rossignol, P. (2016). Renal function estimation and Cockroft-Gault formulas for predicting cardiovascular mortality in population-based, cardiovascular risk, heart failure and post-myocardial infarction cohorts: The Heart 'OMics' in AGEing (HOMAGE) and the high-risk myocardial infarction database initiatives. BMC Medicine, 14(1), Article 181. https://doi.org/10.1186/s12916-016-0731-2
    • Hensgens, K., Merken, J., Hazebroek, M., & Heymans, S. R. B. (2016). Chronic Q fever leads to dilated cardiomyopathy in a 48-year-old male. International Journal of Cardiology, 222, 705-706. https://doi.org/10.1016/j.ijcard.2016.08.024
    • Emans, T. W., Janssen, B. J., Pinkham, M. I., Ow, C. P. C., Evans, R. G., Joles, J. A., Malpas, S. C., Krediet, C. T. P., & Koeners, M. P. (2016). Exogenous and endogenous angiotensin-II decrease renal cortical oxygen tension in conscious rats by limiting renal blood flow. Journal of Physiology, 594(21), 6287-6300. https://doi.org/10.1113/JP270731
    • Choi, Y. S., de Mattos, A. B. M., Shao, D., Li, T., Nabben, M., Kim, M., Wang, W., Tian, R., & Kolwicz, S. C. . J. (2016). Preservation of myocardial fatty acid oxidation prevents diastolic dysfunction in mice subjected to angiotensin II infusion. Journal of Molecular and Cellular Cardiology, 100, 64-71. https://doi.org/10.1016/j.yjmcc.2016.09.001
    • Gupta, S. K., Foinquinos, A., Thum, S., Remke, J., Zimmer, K., Bauters, C., de Groote, P., Boon, R. A., de Windt, L. J., Preissl, S., Hein, L., Batkai, S., Pinet, F., & Thum, T. (2016). Preclinical Development of a MicroRNA-Based Therapy for Elderly Patients With Myocardial Infarction. Journal of the American College of Cardiology, 68(14), 1557-1571. https://doi.org/10.1016/j.jacc.2016.07.739
    • Brandenburg, V. M., Brunner-La Rocca, H., & Marx, N. (2016). Heart Failure Therapy in Patients with Diabetes The new Benefit-Risk-Assessment of Sacubitril/Valsartan. Deutsche Medizinische Wochenschrift, 141(22), 1647-1649. https://doi.org/10.1055/s-0042-000001
    • Vrolijk, M. F., Opperhuizen, A., Jansen, E. H. J. M., Bast, A., & Haenen, G. R. M. M. (2016). Iron Supplements and Magnesium Peroxide: An Example of a Hazardous Combination in Self-Medication. Basic & Clinical Pharmacology & Toxicology, 119(4), 412-417. https://doi.org/10.1111/bcpt.12603
    • Glatz, J. F. C., Nabben, M., Heather, L. C., Bonen, A., & Luiken, J. J. F. P. (2016). Regulation of the subcellular trafficking of CD36, a major determinant of cardiac fatty acid utilization. Biochimica et Biophysica Acta-Molecular and Cell Biology of Lipids, 1861(10), 1461-1471. https://doi.org/10.1016/j.bbalip.2016.04.008
    • Sthijns, M. M. J. P. E., Weseler, A. R., Bast, A., & Haenen, G. R. M. M. (2016). Time in Redox Adaptation Processes: From Evolution to Hormesis. International journal of molecular sciences, 17(10), Article 1649. https://doi.org/10.3390/ijms17101649
    • Summer, G., Kelder, T., Radonjic, M., van Bilsen, M., Wopereis, S., & Heymans, S. (2016). The Network Library: a framework to rapidly integrate network biology resources. Bioinformatics, 32(17), 473-478. https://doi.org/10.1093/bioinformatics/btw436
    • Shi, Q., Haenen, G. R., Maas, L. M., Arlt, V. M., Spina, D., Vasquez, Y. R., Moonen, E., Veith, C., van Schooten, F. J., & Godschalk, R. W. (2016). Inflammation-associated extracellular beta-glucuronidase alters cellular responses to the chemical carcinogen benzo[a]pyrene. Archives of Toxicology, 90(9), 2261-2273. https://doi.org/10.1007/s00204-015-1593-7
    • Daeichin, V., Kooiman, K., Skachkov, I., Bosch, J. G., Theelen, T. L., Steiger, K., Needles, A., Janssen, B. J., Daemen, M. J. A. P., van der Steen, A. F. W., de Jong, N., & Sluimer, J. C. (2016). QUANTIFICATION OF ENDOTHELIAL alpha(V)beta(3) EXPRESSION WITH HIGH-FREQUENCY ULTRASOUND AND TARGETED MICROBUBBLES: IN VITRO AND IN VIVO STUDIES. Ultrasound in Medicine and Biology, 42(9), 2283-2293. https://doi.org/10.1016/j.ultrasmedbio.2016.05.005
    • van Kuijk, S. J. A., Gieling, R. G., Niemans, R., Lieuwes, N. G., Biemans, R., Telfer, B. A., Haenen, G. R. M. M., Yaromina, A., Lambin, P., Dubois, L. J., & Williams, K. J. (2016). The Sulfamate Small Molecule CAIX Inhibitor S4 Modulates Doxorubicin Efficacy. PLOS ONE, 11(8), Article e0161040. https://doi.org/10.1371/journal.pone.0161040
    • Smilde, B. J., Woudstra, L., Hing, G. F., Wouters, D., Zeerleder, S., Murk, J.-L., van Ham, M., Heymans, S., Juffermans, L. J. M., van Rossum, A. C., Niessen, H. W. M., Krijnen, P. A. J., & Emmens, R. W. (2016). Colchicine aggravates coxsackievirus B3 infection in mice. International Journal of Cardiology, 216, 58-65. https://doi.org/10.1016/j.ijcard.2016.04.144
    • Altara, R., Manca, M., Hessel, M. H., Gu, Y., van Vark, L. C., Akkerhuis, K. M., Staessen, J. A., Struyker Boudier, H., Booz, G. W., & Blankesteijn, M. (2016). CXCL10 Is a Circulating Inflammatory Marker in Patients with Advanced Heart Failure: a Pilot Study. Journal of Cardiovascular Translational Research, 9(4), 302-314. https://doi.org/10.1007/s12265-016-9703-3
    • Godschalk, R. W. L., Vanhees, K., Maas, L., Drittij - Reijnders, M. J., Pachen, D., van Doorn-Khosrovani, S. V. W., van Schooten, F. J., & Haenen, G. R. M. M. (2016). Does Ataxia Telangiectasia Mutated (ATM) protect testicular and germ cell DNA integrity by regulating the redox status?Reproductive Toxicology, 63, 169-173. https://doi.org/10.1016/j.reprotox.2016.06.008
    • Maeder, M. T., Zurek, M., Rickli, H., Tobler, D., Kiencke, S., Suter, T., Yoon, S.-I., Julius, B., Pfisterer, M. E., & Brunner-La Rocca, H. (2016). Prognostic Value of the Change in Heart Rate From the Supine to the Upright Position in Patients With Chronic Heart Failure. Journal of the American Heart Association, 5(8), Article e003524. https://doi.org/10.1161/JAHA.116.003524
    • Vurma, M., Dang, L., Brunner-La Rocca, H., Sutsch, G., Attenhofer-Jost, C. H., Duru, F., & Scharf, C. (2016). Safety and efficacy of the nMARQ catheter for paroxysmal and persistent atrial fibrillation. EP Europace, 18(8), 1164-1169. https://doi.org/10.1093/europace/euw048
    • Deckx, S., Heymans, S., & Papageorgiou, A.-P. (2016). The diverse functions of osteoglycin: a deceitful dwarf, or a master regulator of disease?Faseb Journal, 30(8), 2651-2661. https://doi.org/10.1096/fj.201500096R
    • Klinkenberg, L. J. J., Luyten, P., van der Linden, N., Urgel, K., Snijders, D. P. C., Knackstedt, C., Dennert, R., Kietselaer, B. L. J. H., Mingels, A., Cardinaels, E. P. M., Peeters, F. E. C. M., van Suijlen, J. D. E., ten Kate, J., Marsch, E., Theelen, T. L., Sluimer, J. C., Wouters, K., Bekers, O., Bekkers, B., ... Meex, S. J. R. (2016). Cardiac Troponin T and I Release After a 30-km Run. American Journal of Cardiology, 118(2), 281-287. https://doi.org/10.1016/j.amjcard.2016.04.030
    • de Pesters, A., Coon, W. G., Brunner, P., Gunduz, A., Ritaccio, A. L., Brunet, N. M., de Weerd, P., Roberts, M. J., Oostenveld, R., Fries, P., & Schalk, G. (2016). Alpha power indexes task-related networks on large and small scales: A multimodal ECoG study in humans and a non-human primate. Neuroimage, 134, 122-131. https://doi.org/10.1016/j.neuroimage.2016.03.074
    • Smulders, M. W., Kietselaer, B. L. J. H., Schalla, S., Bucerius, J., Jaarsma, C., van Dieijen-Visser, M. P., Mingels, A. M. A., Brunner-La Rocca, H., Post, M., Das, M., Crijns, H. J. G. M., Wildberger, J. E., & Bekkers, B. (2016). Acute chest pain in the high-sensitivity cardiac troponin era: A changing role for noninvasive imaging?American Heart Journal, 177, 102-111. https://doi.org/10.1016/j.ahj.2016.03.025
    • Linssen, P. B. C., Henry, R. M. A., Schalkwijk, C. G., Dekker, J. M., Nijpels, G., Brunner-La Rocca, H., & Stehouwer, C. D. A. (2016). Serum advanced glycation endproducts are associated with left ventricular dysfunction in normal glucose metabolism but not in type 2 diabetes: The Hoorn Study. Diabetes & Vascular Disease Research, 13(4), 278-285. https://doi.org/10.1177/1479164116640680
    • van Ginkel, W. G., Jahja, R., Huijbregts, S. C. J., Daly, A., MacDonald, A., De Laet, C., Cassiman, D., Eyskens, F., Keularts, I., Goyens, P. J., McKiernan, P. J., & van Spronsen, F. J. (2016). Neurocognitive outcome in tyrosinemia type 1 patients compared to healthy controls. Orphanet Journal of Rare Diseases, 11(1), Article 87. https://doi.org/10.1186/s13023-016-0472-5
    • Pinto, Y. M., Elliott, P. M., Arbustini, E., Adler, Y., Anastasakis, A., Boehm, M., Duboc, D., Gimeno, J., de Groote, P., Imazio, M., Heymans, S., Klingel, K., Komajda, M., Limongelli, G., Linhart, A., Mogensen, J., Moon, J., Pieper, P. G., Seferovic, P. M., ... Charron, P. (2016). Proposal for a revised definition of dilated cardiomyopathy, hypokinetic non-dilated cardiomyopathy, and its implications for clinical practice: a position statement of the ESC working group on myocardial and pericardial diseases. European Heart Journal, 37(23), 1850-1858. https://doi.org/10.1093/eurheartj/ehv727
    • Heyninck, K., Sabbe, L., Chirumamilla, C. S., Szic, K. S. V., Veken, P. V., Lemmens, K. J. A., Lahtela-Kakkonen, M., Naulaerts, S., de Beeck, K. O., Laukens, K., Van Camp, G., Weseler, A. R., Bast, A., Haenen, G. R. M. M., Haegeman, G., & Berghe, W. V. (2016). Withaferin A induces heme oxygenase (HO-1) expression in endothelial cells via activation of the Keap1/Nrf2 pathway. Biochemical Pharmacology, 109, 48-61. https://doi.org/10.1016/j.bcp.2016.03.026
    • Poloni, G., De Bortoli, M., Calore, M., Rampazzo, A., & Lorenzon, A. (2016). Arrhythmogenic right-ventricular cardiomyopathy: molecular genetics into clinical practice in the era of next generation sequencing. Journal of Cardiovascular Medicine, 17(6), 399-407. https://doi.org/10.2459/JCM.0000000000000385
    • van Gisbergen, M. W., Cebula, M., Zhang, J., Ottosson-Wadlund, A., Dubois, L., Lambin, P., Tew, K. D., Townsend, D. M., Haenen, G. R. M. M., Drittij - Reijnders, M. J., Saneyoshi, H., Araki, M., Shishido, Y., Ito, Y., Arner, E. S. J., Abe, H., Morgenstern, R., & Johansson, K. (2016). Chemical Reactivity Window Determines Prodrug Efficiency toward Glutathione Transferase Overexpressing Cancer Cells. Molecular Pharmaceutics, 13(6), 2010-2025. https://doi.org/10.1021/acs.molpharmaceut.6b00140
    • Ottaviani, L., De Windt, L. J., & da Costa Martins, P. A. (2016). Exosomes: scytales in the damaged heart. Annals of translational medicine, 4(11), Article 222. https://doi.org/10.21037/atm.2016.05.17
    • Nabben, M., & Neumann, D. (2016). GSK-3 Inhibitors: Anti-Diabetic Treatment Associated with Cardiac Risk?Cardiovascular Drugs and Therapy, 30(3), 233-235. https://doi.org/10.1007/s10557-016-6669-y
    • Gupta, S. K., Itagaki, R., Zheng, X., Batkai, S., Thum, S., Ahmad, F., Van Aelst, L. N., Sharma, A., Piccoli, M.-T., Weinberger, F., Fiedler, J., Heuser, M., Heymans, S., Falk, C. S., Foerster, R., Schrepfer, S., & Thum, T. (2016). miR-21 promotes fibrosis in an acute cardiac allograft transplantation model. Cardiovascular Research, 110(2), 215-226. https://doi.org/10.1093/cvr/cvw030
    • Vegter, E. L., van der Meer, P., de Windt, L. J., Pinto, Y. M., & Voors, A. A. (2016). MicroRNAs in heart failure: from biomarker to target for therapy. European journal of heart failure, 18(5), 457-468. https://doi.org/10.1002/ejhf.495
    • Maessen, D. E., Brouwers, O., Gaens, K. H., Wouters, K., Cleutjens, J. P., Janssen, B. J., Miyata, T., Stehouwer, C. D., & Schalkwijk, C. G. (2016). Delayed Intervention With Pyridoxamine Improves Metabolic Function and Prevents Adipose Tissue Inflammation and Insulin Resistance in High-Fat Diet-Induced Obese Mice. Diabetes, 65(4), 956-966. https://doi.org/10.2337/db15-1390
    • Sanders-van Wijk, S., Masson, S., Milani, V., Rickenbacher, P., Gorini, M., Tavazzi, L. T., Tobler, D., Rickli, H., Latini, R., & Brunner-La Rocca, H. (2016). Interaction of Galectin-3 Concentrations with the Treatment Effects of beta-Blockers and RAS Blockade in Patients with Systolic Heart Failure: A Derivation-Validation Study from TIME-CHF and GISSI-HF. Clinical Chemistry, 62(4), 605-616. https://doi.org/10.1373/clinchem.2015.246850
    • Gast, M., Schroen, B., Voigt, A., Haas, J., Kuehl, U., Lassner, D., Skurk, C., Escher, F., Wang, X., Kratzer, A., Michalik, K., Papageorgiou, A., Peters, T., Loebel, M., Wilk, S., Althof, N., Prasanth, K. V., Katus, H., Meder, B., ... Poller, W. (2016). Long noncoding RNA MALAT1-derived mascRNA is involved in cardiovascular innate immunity. Journal of Molecular Cell Biology, 8(2), 178-181. https://doi.org/10.1093/jmcb/mjw003
    • van Bree, B. W. J., Lenaers, E., Nabben, M., Briede, J. J., Jorgensen, J. A., Schaart, G., Schrauwen, P., Hoeks, J., & Hesselink, M. K. C. (2016). A genistein-enriched diet neither improves skeletal muscle oxidative capacity nor prevents the transition towards advanced insulin resistance in ZDF rats. Scientific Reports, 6, Article 22854. https://doi.org/10.1038/srep22854
    • Dennert, R., Streukens, B., Gommers, S., Heymans, S., & Bekkers, B. (2016). Perimyocarditis Complicated by Early Development of Constrictive Pericarditis. Canadian Journal of Cardiology, 32(3), 395.e11-395.e12. https://doi.org/10.1016/j.cjca.2015.06.004
    • Peters, T., Beijnsberger, S., Beqqali, A., Bitsch, N., Nakagawa, S., Prasanth, K. V., de Windt, L. J., van Oort, R. J., Heymans, S., & Schroen, B. (2016). Long Non-Coding RNA Malat-1 Is Dispensable during Pressure Overload-Induced Cardiac Remodeling and Failure in Mice. PLOS ONE, 11(2), Article e0150236. https://doi.org/10.1371/journal.pone.0150236
    • Viereck, J., Kumarswamy, R., Foinquinos, A., Xiao, K., Avramopoulos, P., Kunz, M., Dittrich, M., Maetzig, T., Zimmer, K., Remke, J., Just, A., Fendrich, J., Scherf, K., Bolesani, E., Schambach, A., Weidemann, F., Zweigerdt, R., de Windt, L. J., Engelhardt, S., ... Thum, T. (2016). Long noncoding RNA Chast promotes cardiac remodeling. Science Translational Medicine, 8(326), Article 326ra22. https://doi.org/10.1126/scitranslmed.aaf1475
    • Lupon, J., Sanders-van Wijk, S., Januzzi, J. L., de Antonio, M., Gaggin, H. K., Pfisterer, M., Galan, A., Shah, R., Brunner-La Rocca, H., & Bayes-Genis, A. (2016). Prediction of survival and magnitude of reverse remodeling using the ST2-R2 score in heart failure: A multicenter study. International Journal of Cardiology, 204, 242-247. https://doi.org/10.1016/j.ijcard.2015.11.163
    • Ruijters, E., Haenen, G. R., Willemsen, M., Weseler, A. R., & Bast, A. (2016). Food-Derived Bioactives Can Protect the Anti-Inflammatory Activity of Cortisol with Antioxidant-Dependent and -Independent Mechanisms. International journal of molecular sciences, 17(2), Article 239. https://doi.org/10.3390/ijms17020239
    • Kriemler, S., Radtke, T., Bürgi, F., Lambrecht, J., Zehnder, M., & Brunner-La Rocca, H. (2016). Short-term cardiorespiratory adaptation to high altitude in children compared with adults. Scandinavian Journal of Medicine & Science in Sports, 26(2), 147-155. https://doi.org/10.1111/sms.12422
    • Duygu, B., de Windt, L. J., & Da Costa Martins, P. (2016). Targeting microRNAs in heart failure. Trends in Cardiovascular Medicine, 26(2), 99-110. https://doi.org/10.1016/j.tcm.2015.05.008
    • Marsch, E., Theelen, T., Janssen, B. J., Briedé, J. J., Haenen, G. R., Senden, J., van Loon, L. J., Poeze - van Bokhoven, M., Bierau, J., Gijbels, M. J., Daemen, M. J., & Sluimer, J. (2016). The effect of prolonged dietary nitrate supplementation on atherosclerosis development. Atherosclerosis, 245, 212-221. https://doi.org/10.1016/j.atherosclerosis.2015.11.031