Robert van Oostenbrugge

Professor

Robert van Oostenbrugge is Professor of Neurology, with a chair on Vascular Neurology, head of the Department of Neurology (UM); principal Investigator of CARIM and programme leader of Vascular Neurology / Stroke. Robert (R.J.) van Oostenbrugge; (born Havelte, 1965) obtained a MD at the Maastricht University in Maastricht (1990). He was registered as neurologist in 2000 and obtained a PhD in 1999 (University Maastricht, Maastricht). In 2013, he was appointed Professor of Neurology chair of the Department of Neurology at Maastricht University. He is member of the Centers of Excellence in Neurodegeneration initiative and of the JPND funded initiative HARNESS aiming to harmonise imaging standards in vascular dementia, member of the board of the Dutch Section of Vascular Neurology.

Department of Neurology
P. Debyelaan 25, 6229 HX Maastricht 
PO Box 5800, 6202 AZ Maastricht
T: +31 (0)43 387 70 58

 

  • 2024
    • Voorter, P. H. M., Stringer, M. S., van Dinther, M., Kerkhofs, D., Dewenter, A., Blair, G. W., Thrippleton, M. J., Jaime Garcia, D., Chappell, F. M., Janssen, E., Kopczak, A., Staals, J., Ingrisch, M., Duering, M., Doubal, F. N., Dichgans, M., van Oostenbrugge, R. J., Jansen, J. F. A., Wardlaw, J. M., ... SVDs@target Consortium (2024). Heterogeneity and Penumbra of White Matter Hyperintensities in Small Vessel Diseases Determined by Quantitative MRI. Stroke. Advance online publication. https://doi.org/10.1161/STROKEAHA.124.047910
    • Robbe, M. M. Q., Pinckaers, F. M. E., Wagemans, B. A. J. M., van Oostenbrugge, R. J., van Zwam, W. H., Staals, J., & Postma, A. A. (2024). Additional value of CTP maps in occlusion detection on CTP angiographic reconstructions for ischemic stroke. European Journal of Radiology, 181, Article 111789. https://doi.org/10.1016/j.ejrad.2024.111789
    • Robbe, M. M. Q., Pinckaers, F. M. E., Wagemans, B. A. J. M., van Oostenbrugge, R. J., van Zwam, W. H., Staals, J., & Postma, A. A. (2024). Angiographic reconstructions of CT perfusion for occlusion detection in ischemic stroke. European Journal of Radiology, 181, Article 111819. https://doi.org/10.1016/j.ejrad.2024.111819
    • Knapen, R. R. M. M., Celen, M., Benali, F., van Oostenbrugge, R. J., van Zwam, W. H., & van der Leij, C. (2024). The use of a (non-) balloon guide catheter in endovascular stroke treatment, a registry of real-life use and nationwide questionnaire. Journal of Stroke & Cerebrovascular Diseases, 33(12), Article 108033. https://doi.org/10.1016/j.jstrokecerebrovasdis.2024.108033
    • Pinckaers, F. M. E., Grutters, J. P. C., Huijberts, I., Gabrio, A., Boogaarts, H. D., Postma, A. A., van Oostenbrugge, R. J., van Zwam, W. H., & Evers, S. M. A. A. (2024). Author's Response to Letter to the Editor Titled "Potential Biases in Post-stroke Health Utility Estimates by Modified Rankin Scale Scores". Value in Health. Advance online publication. https://doi.org/10.1016/j.jval.2024.10.3854
    • Berends, E., Pencheva, M. G., van de Waarenburg, M. P. H., Scheijen, J. L. J. M., Hermes, D. J. H. P., Wouters, K., van Oostenbrugge, R. J., Foulquier, S., & Schalkwijk, C. G. (2024). Glyoxalase 1 overexpression improves neurovascular coupling and limits development of mild cognitive impairment in a mouse model of type 1 diabetes. Journal of Physiology, 602(22), 6209-6223. https://doi.org/10.1113/JP286723
    • Voorter, P. H. M., Jansen, J. F. A., van der Thiel, M. M., van Dinther, M., Postma, A. A., van Oostenbrugge, R. J., Gurney-Champion, O. J., Drenthen, G. S., & Backes, W. H. (2024). Diffusion-derived intravoxel-incoherent motion anisotropy relates to CSF and blood flow. Magnetic Resonance in Medicine. Advance online publication. https://doi.org/10.1002/mrm.30294
    • Stringer, M. S., Blair, G. W., Kopczak, A., Kerkhofs, D., Thrippleton, M. J., Chappell, F. M., Maniega, S. M., Brown, R., Shuler, K., Hamilton, I., Garcia, D. J., Doubal, F. N., Clancy, U., Sakka, E., Poliakova, T., Janssen, E., Duering, M., Ingrisch, M., Staals, J., ... Wardlaw, J. M. (2024). Cerebrovascular Function in Sporadic and Genetic Cerebral Small Vessel Disease. Annals of Neurology. Advance online publication. https://doi.org/10.1002/ana.27136
    • Robbe, M. M. Q., Pinckaers, F. M. E., van Kuijk, S. M. J., van Oostenbrugge, R. J., van Zwam, W. H., & Postma, A. A. (2024). Post-endovascular therapy contrast extravasation in the mesial temporal region on dual-energy CT is associated with outcome in acute ischemic stroke patients. Journal of Stroke & Cerebrovascular Diseases, 33(11), Article 107949. https://doi.org/10.1016/j.jstrokecerebrovasdis.2024.107949
    • Kassem, M., Crombag, G. A. J. C., Stegers, J., Liem, M. I., Koornstra, E., Schreuder, F. H. B. M., van Dam-Nolen, D. H. K., Lucci, C., van der Geest, R. J., Daemen, M. J., van der Steen, A. F. W., Hendrikse, J., Mess, W. H., Bos, D., Wildberger, J. E., van Oostenbruggeb, R. J., Nederkoorn, P. J., & Kooi, M. E. (2024). Association between Antiplatelet Therapy and Changes in Intraplaque Hemorrhage in Patients with Mild to Moderate Symptomatic Carotid Stenosis: a longitudinal MRI study. Cerebrovascular Diseases, 53(5), 598-606. https://doi.org/10.1159/000535274
    • van den Kerkhof, M., de Jong, J. J. A., Voorter, P. H. M., Postma, A., Kroon, A. A., van Oostenbrugge, R. J., Jansen, J. F. A., & Backes, W. H. (2024). Blood-Brain Barrier Integrity Decreases With Higher Blood Pressure: A 7T DCE-MRI Study. Hypertension, 81(10), 2162-2172. https://doi.org/10.1161/HYPERTENSIONAHA.123.22617
    • Peeters, M. T. J., Postma, A. A., van Oostenbrugge, R. J., Henneman, W. J. P., & Staals, J. (2024). Dual-energy CT angiography in detecting underlying causes of intracerebral hemorrhage: an observational cohort study. Neuroradiology. https://doi.org/10.1007/s00234-024-03473-1
    • Berends, E., Vangrieken, P., Amiri, N., van de Waarenburg, M. P. H., Scheijen, J. L. J. M., Hermes, D. J. H. P., Wouters, K., van Oostenbrugge, R. J., Schalkwijk, C. G., & Foulquier, S. (2024). Increased Levels of Circulating Methylglyoxal Have No Consequence for Cerebral Microvascular Integrity and Cognitive Function in Young Healthy Mice. Molecular Neurobiology. Advance online publication. https://doi.org/10.1007/s12035-024-04552-3
    • Fandler-Höfler, S., Eppinger, S., Ambler, G., Nash, P., Kneihsl, M., Lee, K. J., Lim, J. S., Shiozawa, M., Koga, M., Li, L., Lovelock, C., Chabriat, H., Hennerici, M., Wong, Y. K., Mak, H. K. F., Prats-Sanchez, L., Martínez-Domeño, A., Inamura, S., Yoshifuji, K., ... Microbleeds International Collaborative Network (2024). Sex Differences in Frequency, Severity, and Distribution of Cerebral Microbleeds. Jama network open, 7(10), Article e2439571. https://doi.org/10.1001/jamanetworkopen.2024.39571
    • Coenen, M., de Kort, F. A. S., Weaver, N. A., Kuijf, H. J., Aben, H. P., Bae, H.-J., Bordet, R., Chen, C. L., Dewenter, A., Doeven, T., Dondaine, T., Duering, M., Fang, R., van der Giessen, R. S., Kim, J., Kim, B. J., de Kort, P. L. M., Koudstaal, P., Lee, M., ... Biesbroek, J. M. (2024). Strategic white matter hyperintensity locations associated with post-stroke cognitive impairment: a multicenter study in 1568 stroke patients. International journal of stroke, 19(8), 916-924. https://doi.org/10.1177/17474930241252530
    • van Dinther, M., Voorter, P. H. M., Zhang, E., van Kuijk, S. M. J., Jansen, J. F. A., van Oostenbrugge, R. J., Backes, W. H., & Staals, J. (2024). The neurovascular unit and its correlation with cognitive performance in patients with cerebral small vessel disease: a canonical correlation analysis approach. Geroscience, 46(5), 5061-5073. https://doi.org/10.1007/s11357-024-01235-8
    • Huijberts, I., Pinckaers, F. M. E., Olthuis, S. G. H., van Kuijk, S. M. J., Postma, A. A., Boogaarts, H. D., Roos, Y. B. W. E. M., Majoie, C. B. L. M., van der Lugt, A., Dippel, D. W. J., van Zwam, W. H., van Oostenbrugge, R. J., & MR CLEAN-LATE Investigators (2024). Collateral-based selection for endovascular treatment of acute ischaemic stroke in the late window (MR CLEAN-LATE): 2-year follow-up of a phase 3, multicentre, open-label, randomised controlled trial in the Netherlands. Lancet Neurology, 23(9), 893-900. https://doi.org/10.1016/S1474-4422(24)00228-X
    • Knapen, R. R. M. M., Simon, S. R., Robbe, M. M. Q., Jongkind, J., Brans, R., de Ridder, I. R., van Oostenbrugge, R. J., van Zwam, W. H., & van der Leij, C. (2024). Comparison of clinical, technical, and safety outcomes between the Sofia 5Fr catheter vs. the Sofia 6Fr catheter; a MaSQ-Registry study. Journal of Stroke & Cerebrovascular Diseases, 33(11), Article 107967. https://doi.org/10.1016/j.jstrokecerebrovasdis.2024.107967
    • van Voorst, H., Pitkanen, J., van Poppel, L., de Vries, L., Mojtahedi, M., Martou, L., Emmer, B. J., Roos, Y. B. W. E. M., van Oostenbrugge, R., Postma, A. A., Marquering, H. A., Majoie, C. B. L. M., Curtze, S., Melkas, S., Bentley, P., Caan, M. W. A., CONTRAST Consortium Collaborators, & MR CLEAN No IV (2024). Deep learning-based white matter lesion volume on CT is associated with outcome after acute ischemic stroke. European Radiology, 34(8), 5080-5093. https://doi.org/10.1007/s00330-024-10584-z
    • Zonneveld, T. P., Vermeer, S. E., van Zwet, E. W., Groot, A. E. D., Algra, A., Aerden, L. A. M., Alblas, K. C. L., de Beer, F., Brouwers, P. J. A. M., de Gans, K., van Gemert, H. M. A., van Ginneken, B. C. A. M., Grooters, G. S., Halkes, P. H. A., van der Heijden-Montfroy, T. A. M. H. G., Jellema, K., de Jong, S. W., Lövenich-Ciccarello, H., van der Meulen, W. D. M., ... Kruyt, N. D. (2024). Safety and efficacy of active blood-pressure reduction to the recommended thresholds for intravenous thrombolysis in patients with acute ischaemic stroke in the Netherlands (TRUTH): a prospective, observational, cluster-based, parallel-group study. Lancet Neurology, 23(8), 807-815. https://doi.org/10.1016/S1474-4422(24)00177-7
    • Immens, M. H., Ekker, M. S., Verburgt, E., Verhoeven, J. I., Schellekens, M. M., Hilkens, N. A., Boot, E. M., Van Alebeek, M. E., Brouwers, P. J., Arntz, R. M., Van Dijk, G. W., Gons, R. A., Van Uden, I. W., den Heijer, T., de Kort, P. L., de Laat, K. F., Van Norden, A. G., Vermeer, S. E., Van Zagten, M. S., ... de Leeuw, F.-E. (2024). Trigger factors in patients with a patent foramen ovale-associated stroke: A case-crossover study. International journal of stroke, 19(7), 809-816. https://doi.org/10.1177/17474930241242625
    • Knapen, R. R. M. M., Olthuis, S. G. H., van Es, A. C. G. M., Emmer, B. J., Schonewille, W. J., van der Leij, C., van Zwam, W. H., van Oostenbrugge, R. J., & MR CLEAN LATE Trial investigators (2024). Association of first-line thrombectomy technique and outcome in late-window large vessel occlusion strokes: A post hoc analysis of the MR CLEAN-LATE trial. International journal of stroke. https://doi.org/10.1177/17474930241268303
    • Knapen, R. R. M. M., Goldhoorn, R.-J. B., Hofmeijer, J., Lycklamaa Nijeholt, G. J., van den Berg, R., van den Wijngaard, I. R., van Oostenbrugge, R. J., van Zwam, W. H., van der Leij, C., MR CLEAN Registry Investigators, Goldhoorn, R.-J., Hinsenveld, W., Staals, J., Postma - Jacobi, L., Brans, R., Olthuis, S., & Pinckaers, F. (2024). Balloon Guide Catheter Versus Non-Balloon Guide Catheter: A MR CLEAN Registry Analysis. Stroke: vascular and interventional neurology, 4(4), Article e001103. https://doi.org/10.1161/SVIN.123.001103
    • Knapen, R. R. M. M., Celen, M., Pinckaers, F. M. E., Wagemans, B. A. J. M., van Zwam, W. H., van Oostenbrugge, R. J., & van der Leij, C. (2024). Comparison of Clinical and Radiological Outcomes Between Different (Balloon) Guide Catheter With and Without Inflated Balloon in Acute Ischemic Stroke Patients: A MaSQ-Registry Study. Cardiovascular and Interventional Radiology, 47(7), 918-928. https://doi.org/10.1007/s00270-024-03718-9
    • Nies, K. P. H., Aizaz, M., van Dam-Nolen, D. H. K., Goring, T. C. D., Schreuder, T. A. H. C. M. L., van Orshoven, N. P., Postma, A. A., Bos, D., Hendrikse, J., Nederkoorn, P., van der Geest, R., van Oostenbrugge, R. J., Mess, W. H., & Kooi, M. E. (2024). Signal intensity and volume of carotid intraplaque hemorrhage on magnetic resonance imaging and the risk of ipsilateral cerebrovascular events: the Plaque At RISK (PARISK) study. Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance, 26(2), Article 101049. https://doi.org/10.1016/j.jocmr.2024.101049
    • Schellekens, M. M. I., Springer, R. C. S., Boot, E. M., Verhoeven, J. I., Ekker, M. S., van Alebeek, M. E., Brouwers, P. J. A. M., Arntz, R. M., van Dijk, G. W., Gons, R. A. R., van Uden, I. W. M., den Heijer, T., van Tuijl, J. H., de Laat, K. F., van Norden, A. G. W., Vermeer, S. E., van Zagten, M. S. G., Van Oostenbrugge, R. J., Wermer, M. J. H., ... Tuladhar, A. M. (2024). Cognitive trajectory in the first year after first-ever ischaemic stroke in young adults: the ODYSSEY study. Journal of Neurology Neurosurgery and Psychiatry, 95(6), 571-579. https://doi.org/10.1136/jnnp-2023-332104
    • Van Voorst, H., Hoving, J. W., Koopman, M. S., Daems, J. D., Peerlings, D., Buskens, E., Lingsma, H., Marquering, H. A., De Jong, H. W. A. M., Berkhemer, O. A., Van Zwam, W. H., Van Walderveen, M. A. A., Van Den Wijngaard, I. R., Dippel, D. W. J., Yoo, A. J., Campbell, B., Kunz, W. G., Majoie, C. B., Emmer, B. J., ... MR CLEAN Registry Investigators (2024). Costs and health effects of CT perfusion-based selection for endovascular thrombectomy within 6 hours of stroke onset: a model-based health economic evaluation. Journal of Neurology Neurosurgery and Psychiatry, 95(6), 515-527. https://doi.org/10.1136/jnnp-2023-331862
    • Pinckaers, F. M., Evers, S. M., Olthuis, S. G., Boogaarts, H. D., Postma, A. A., van Oostenbrugge, R. J., van Zwam, W. H., & Grutters, J. P. (2024). Cost-effectiveness of endovascular treatment after 6-24?h in ischaemic stroke patients with collateral flow on CT-angiography: A model-based economic evaluation of the MR CLEAN-LATE trial. European Stroke Journal, 9(2), 348-355. https://doi.org/10.1177/23969873231220464
    • Pinckaers, F. M. E., Robbe, M. M. Q., Olthuis, S. G. H., Boogaarts, H. D., van Zwam, W. H., van Oostenbrugge, R. J., & Postma, A. A. (2024). Prognostic Implications of Intracranial Haemorrhage on Dual-Energy CT Immediately Following Endovascular Treatment for Acute Ischemic Stroke. Journal of Neuroradiology, 51(4), Article 101168. https://doi.org/10.1016/j.neurad.2023.11.003
    • Knapen, R. R. M. M., Frol, S., van Kuijk, S. M. J., Oblak, J. P., van der Leij, C., van Oostenbrugge, R. J., & van Zwam, W. H. (2024). Intravenous thrombolysis for ischemic stroke in the posterior circulation: A systematic review and meta-analysis. Journal of Stroke and Cerebrovascular Diseases , 33(5), Article 107641. https://doi.org/10.1016/j.jstrokecerebrovasdis.2024.107641
    • Simon, S. R., Knapen, R. R. M. M., Truijman, M. T. B., van Oostenbrugge, R. J., Wagemans, B. A. J. M., van Zwam, W. H., & van der Leij, C. (2024). Timing of acute carotid artery stenting for tandem lesions in patients with acute ischemic stroke: A Maastricht Stroke Quality Registry (MaSQ-Registry) study. Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences, Article 15910199241245166. Advance online publication. https://doi.org/10.1177/15910199241245166
    • Pinckaers, F. M. E., Grutters, J. P. C., Huijberts, I., Gabrio, A., Boogaarts, H. D., Postma, A. A., van Oostenbrugge, R. J., van Zwam, W. H., & Evers, S. M. A. A. (2024). Cost- and Utility Estimates per Modified Rankin Scale-Score up to 2 Years Post-Stroke: Data to Inform Economic Evaluations from a Societal Perspective. Value in Health, 27(4), 441-448. https://doi.org/10.1016/j.jval.2024.01.001
    • van Voorst, H., Hoving, J. W., Koopman, M. S., Daems, J. D., Peerlings, D., Buskens, E., Lingsma, H. F., Beenen, L. F. M., de Jong, H. W. A. M., Berkhemer, O. A., van Zwam, W. H., Roos, Y. B. W. E. M., van Walderveen, M. A. A., van den Wijngaard, I., Dippel, D. W. J., Yoo, A. J., Campbell, B. C. V., Kunz, W. G., Emmer, B. J., ... MR CLEAN Registry Investigators (2024). Cost-effectiveness of CT perfusion for the detection of large vessel occlusion acute ischemic stroke followed by endovascular treatment: a model-based health economic evaluation study. European Radiology, 34(4), 2152-2167. https://doi.org/10.1007/s00330-023-10119-y
    • Ceulemans, A., Spronk, H. M. H., Ten Cate, H., van Zwam, W. H., van Oostenbrugge, R. J., & Nagy, M. (2024). Current and potentially novel antithrombotic treatment in acute ischemic stroke. Thrombosis Research, 236, 74-84. https://doi.org/10.1016/j.thromres.2024.02.009
    • Vos, E. M., Kappelhof, M., den Hartog, S. J., Coutinho, J. M., Emmer, B. J., Roozenbeek, B., van Zwam, W. H., van Oostenbrugge, R. J., van der Worp, H. B., Uyttenboogaart, M., van Es, A. C. G. M., Majoie, C. B. L. M., Dippel, D. W. J., Peeters-Scholte, C. M. P. C. D., van den Wijngaard, I. R., & MR CLEAN Registry Investigators (2024). Endovascular treatment of patients with stroke caused by anterior cerebral artery occlusions. Acta neurologica Belgica, 124(2), 621-630. https://doi.org/10.1007/s13760-023-02395-8
    • Oestreich, L. K., Lo, J. W., Di Biase, M. A., Sachdev, P. S., Mok, A. H., Wright, P., Crawford, J. D., Lam, B., Traykov, L., Köhler, S., Staals, J. E., van Oostenbrugge, R., Chen, C., Desmond, D. W., Yu, K.-H., Lee, M., Klimkowicz-Mrowiec, A., Bordet, R., O'Sullivan, M. J., & Zalesky, A. (2024). Network analysis of neuropsychiatric, cognitive, and functional complications of stroke: implications for novel treatment targets. Psychiatry and Clinical Neurosciences, 78(4), 229-236. https://doi.org/10.1111/pcn.13633
    • Robbe, M. M. Q., Pinckaers, F. M. E., Olthuis, S. G. H., Bos, M. J., van Oostenbrugge, R. J., van Zwam, W. H., Staals, J., & Postma, A. A. (2024). Procedural Blood Pressure and Intracranial Hemorrhage on Dual-Energy Computed Tomography After Endovascular Stroke Treatment. Cardiovascular and Interventional Radiology, 47(4), 483-491. https://doi.org/10.1007/s00270-023-03619-3
    • Trieu, C., van Harten, A. C., Leeuwis, A. E., Exalto, L. G., Hooghiemstra, A. M., Verberk, I. M. W., Allaart, C. P., Brunner-La Rocca, H.-P., Kappelle, L. J., van Oostenbrugge, R. J., Biessels, G.-J., Teunissen, C. E., van der Flier, W. M., & Heart-Brain Connection Consortium (2024). Alzheimer's Disease and Cognitive Decline in Patients with Cardiovascular Diseases Along the Heart-Brain Axis. Journal of Alzheimer's Disease, 98(3), 987-1000. https://doi.org/10.3233/JAD-231096
    • Robbe, M. M. Q., Pinckaers, F. M. E., Santegoeds, R. G. C., Bos, M. J., van Oostenbrugge, R. J., van Zwam, W. H., Staals, J., & Postma, A. A. (2024). Procedural blood pressure and contrast extravasation on dual energy computed tomography after endovascular stroke treatment. Journal of Stroke & Cerebrovascular Diseases, 33(6), Article 107673. https://doi.org/10.1016/j.jstrokecerebrovasdis.2024.107673
    • Kaesmacher, J., Cavalcante, F., Kappelhof, M., Treurniet, K. M., Rinkel, L., Liu, J., Yan, B., Zi, W., Kimura, K., Eker, O. F., Zhang, Y., Piechowiak, E. I., van Zwam, W., Liu, S., Strbian, D., Uyttenboogaart, M., Dobrocky, T., Miao, Z., Suzuki, K., ... IRIS Collaborators (2024). Time to Treatment With Intravenous Thrombolysis Before Thrombectomy and Functional Outcomes in Acute Ischemic Stroke: A Meta-Analysis. JAMA-Journal of the American Medical Association, 331(9), 764-777. https://doi.org/10.1001/jama.2024.0589
    • Hoving, J. W., Konduri, P. R., Tolhuisen, M. L., Koopman, M. S., van Voorst, H., Van Poppel, L. M., Daems, J. D., van Es, A. C. G. M., van Walderveen, M. A. A., Lingsma, H. F., Dippel, D. W. J., Van Zwam, W. H., Marquering, H. A., Majoie, C. B. L. M., Emmer, B. J., MR CLEAN Registry Investigators, van Oostenbrugge, R. J., Goldhoorn, R.-J., Hinsenveld, W., ... Pinckaers, F. (2024). Impact of Intracranial Volume and Brain Volume on the Prognostic Value of Computed Tomography Perfusion Core Volume in Acute Ischemic Stroke. Journal of Cardiovascular Development and Disease, 11(3), Article 80. https://doi.org/10.3390/jcdd11030080
    • Robbe, M. M. Q., Pinckaers, F. M. E., van Oostenbrugge, R. J., van Zwam, W. H., & Postma, A. A. (2024). The correlation between CT perfusion deficits and immediate post-endovascular treatment contrast extravasation on dual energy CT in acute ischemic stroke patients. European Journal of Radiology, 173, Article 111379. https://doi.org/10.1016/j.ejrad.2024.111379
    • Voorter, P. H. M., van Dinther, M., Jansen, W. J., Postma, A. A., Staals, J., Jansen, J. F. A., van Oostenbrugge, R. J., van der Thiel, M. M., & Backes, W. H. (2024). Blood-Brain Barrier Disruption and Perivascular Spaces in Small Vessel Disease and Neurodegenerative Diseases: A Review on MRI Methods and Insights. Journal of Magnetic Resonance Imaging, 59(2), 397-411. Article jmri28989. https://doi.org/10.1002/jmri.28989
    • Knapen, R. R. M. M., Pirson, F. A. V., Langezaal, L. C. M., Brouwer, J., Majoie, C. B. L. M., Emmer, B. J., Vos, J.-A., van Doormaal, P.-J., Yoo, A. J., Bruggeman, A. A. E., Lycklama À Nijeholt, G. J., van der Leij, C., van Oostenbrugge, R. J., van Zwam, W. H., Schonewille, W. J., MR CLEAN Registry Investigators, Goldhoorn, R.-J., Hinsenveld, W., Staals, J., ... Pirson, A.-F. (2024). Intravenous Thrombolysis Before Endovascular Treatment in Posterior Circulation Occlusions: A MR CLEAN Registry Study. Stroke, 55(2), 403-412. https://doi.org/10.1161/STROKEAHA.123.043777
    • Verburgt, E., Hilkens, N. A., Ekker, M. S., Schellekens, M. M. I., Boot, E. M., Immens, M. H. M., van Alebeek, M. E., Brouwers, P. J. A. M., Arntz, R. M., van Dijk, G. W., Gons, R. A. R., van Uden, I. W. M., den Heijer, T., van Tuijl, J. H., de Laat, K. F., van Norden, A. G. W., Vermeer, S. E., van Zagten, M. S. G., van Oostenbrugge, R. J., ... Verhoeven, J. I. (2024). Short-Term and Long-Term Risk of Recurrent Vascular Event by Cause After Ischemic Stroke in Young Adults. Jama network open, 7(2), Article 240054. https://doi.org/10.1001/jamanetworkopen.2024.0054
    • Ceulemans, A., Pinckaers, F. M. E., Postma, A. A., van Zwam, W. H., & van Oostenbrugge, R. J. (2024). Association Between Anemia and Clinical Outcome in Acute Ischemic Stroke Patients Treated With Endovascular Treatment. Journal of Stroke, 26(1), 87-94. https://doi.org/10.5853/jos.2023.01669
    • van Dinther, M. M., Hooghiemstra, A. E., Bron, E., Versteeg, A. E., Leeuwis, A., Kalay, T. E., Moonen, J., Kuipers, S. H., Backes, W., Jansen, J. F. A., van Osch, M. J. P., Biessels, G.-J., Staals, J. J., van Oostenbrugge, R., & Heart-Brain Connection Consortium (2024). Lower cerebral blood flow predicts cognitive decline in patients with vascular cognitive impairment. Alzheimer's & Dementia, 20(1), 136-144. https://doi.org/10.1002/alz.13408
  • 2023
    • Bakker, L., Ramakers, I. H. G. B., J P M Eussen, S., Choe, K., van den Hove, D. L. A., Kenis, G., Rutten, B. P. F., van Oostenbrugge, R. J., Staals, J., Ulvik, A., Ueland, P. M., Verhey, F. R. J., & Köhler, S. (2023). The role of the kynurenine pathway in cognitive functioning after stroke: A prospective clinical study. Journal of the neurological sciences, 454(1), Article 120819. https://doi.org/10.1016/j.jns.2023.120819
    • Barlinn, K., Langezaal, L. C. M., Dippel, D. W. J., Van, W. H., Roessler, M., Roos, Y. B. W. E. M., Emmer, B. J., van Oostenbrugge, R. J., Gerber, J. C., Yoo, A. J., Pontes-Neto, O. M., Mazighi, M., Audebert, H. J., Michel, P., Schonewille, W. J., Puetz, V., & BASICS Study Group (2023). Early Intubation in Endovascular Therapy for Basilar Artery Occlusion: A Post Hoc Analysis of the BASICS Trial. Stroke, 54(11), 2745-2754. https://doi.org/10.1161/STROKEAHA.123.043669
    • Kopczak, A., Stringer, M. S., van den Brink, H., Kerkhofs, D., Blair, G. W., van Dinther, M., Reyes, C. A., Garcia, D. J., Onkenhout, L., Wartolowska, K. A., Thrippleton, M. J., Kampaite, A., Duering, M., Staals, J., Lesnik-Oberstein, S., Muir, K. W., Middeke, M., Norrving, B., Bousser, M. G., ... TREAT-SVDs collaborators (2023). Effect of blood pressure-lowering agents on microvascular function in people with small vessel diseases (TREAT-SVDs): a multicentre, open-label, randomised, crossover trial. Lancet Neurology, 22(11), 991-1004. https://doi.org/10.1016/S1474-4422(23)00293-4