Robert van Oostenbrugge

Professor

Robert van Oostenbrugge is Professor of Neurology, with a chair on Vascular Neurology, head of the Department of Neurology (UM); principal Investigator of CARIM and programme leader of Vascular Neurology / Stroke. Robert (R.J.) van Oostenbrugge; (born Havelte, 1965) obtained a MD at the Maastricht University in Maastricht (1990). He was registered as neurologist in 2000 and obtained a PhD in 1999 (University Maastricht, Maastricht). In 2013, he was appointed Professor of Neurology chair of the Department of Neurology at Maastricht University. He is member of the Centers of Excellence in Neurodegeneration initiative and of the JPND funded initiative HARNESS aiming to harmonise imaging standards in vascular dementia, member of the board of the Dutch Section of Vascular Neurology.

Department of Neurology
P. Debyelaan 25, 6229 HX Maastricht
PO Box 5800, 6202 AZ Maastricht
T: +31 (0)43 387 70 58

2023
- van den Kerkhof, M., van der Thiel, M. M., van Oostenbrugge, R. J., Postma, A. A., Kroon, A. A., Backes, W. H., & Jansen, J. F. (2023). Impaired damping of cerebral blood flow velocity pulsatility is associated with the number of perivascular spaces as measured with 7T MRI. Journal of Cerebral Blood Flow and Metabolism, 43(6), 937-946. https://doi.org/10.1177/0271678X231153374
- Benali, F., Kappelhof, M., Ospel, J., Ganesh, A., McDonough, R. V., Postma, A. A., Goldhoorn, R.-J. B., Majoie, C. B. L. M., van den Wijngaard, I., Lingsma, H. F., Vos, J. A., van Oostenbrugge, R. J., van Zwam, W. H., Goyal, M., & MR CLEAN Registry Investigators (2023). Benefit of successful reperfusion achieved by endovascular thrombectomy for patients with ischemic stroke and moderate pre-stroke disability (mRS 3): results from the MR CLEAN Registry. Journal of Neurointerventional Surgery, 15(5), 433-438. https://doi.org/10.1136/neurintsurg-2022-018853
- Olthuis, S. G. H., Pirson, F. A. V., Pinckaers, F. M. E., Hinsenveld, W. H., Nieboer, D., Ceulemans, A., Knapen, R. R. M. M., Robbe, M. M. Q., Berkhemer, O. A., van Walderveen, M. A. A., Lycklama À Nijeholt, G. J., Uyttenboogaart, M., Schonewille, W. J., van der Sluijs, P. M., Wolff, L., van Voorst, H., Postma, A. A., Roosendaal, S. D., van der Hoorn, A., ... MR CLEAN-LATE Investigators (2023). Endovascular treatment versus no endovascular treatment after 6-24 h in patients with ischaemic stroke and collateral flow on CT angiography (MR CLEAN-LATE) in the Netherlands: a multicentre, open-label, blinded-endpoint, randomised, controlled, phase 3 trial. Lancet, 401(10385), 1371-1380. https://doi.org/10.1016/S0140-6736(23)00575-5
- Brouwer, J., Ergezen, S., Mulder, M. J. H. L., Nijeholt, G. J. L. A., Van Es, A. C. G. M., Van Der Lugt, A., Dippel, D. W. J., Majoie, C. B. L. M., Roos, Y. B. W. E. M., Coutinho, J. M., Emmer, B. J., Van Oostenbrugge, R. J., Van Zwam, W. H., Boiten, J., Vos, J. A., Jansen, I. G. H., Goldhoorn, R. J. B., Compagne, K. C. J., Kappelhof, M., ... MR CLEAN Registry Investigators (2023). Endovascular treatment for isolated posterior cerebral artery occlusion stroke in the MR CLEAN registry. Journal of Neurointerventional Surgery, 15(4), 363-369. https://doi.org/10.1136/neurintsurg-2021-018505
- van den Kerkhof, M., van der Thiel, M. M., Postma, A. A., van Oostenbrugge, R. J., Kroon, A. A., Jansen, J. F. A., & Backes, W. H. (2023). Hypertension Correlates With Stronger Blood Flow Pulsatility in Small Perforating Cerebral Arteries Assessed With 7 Tesla Magnetic Resonance Imaging. Hypertension, 80(4), 802-810. https://doi.org/10.1161/HYPERTENSIONAHA.122.19866
- Terreros, N. A., Bruggeman, A. A. E., van Voorst, H., Konduri, P. R., Jansen, I. G. H., Kappelhof, M., Tolhuisen, M. L., Boodt, N., Dippel, D. W. J., van der Lugt, A., van Zwam, W. H., van Oostenbrugge, R. J., van der Worp, H. B., Emmer, B. J., Meijer, F. J. A., Roos, Y. B. W. E. M., van Bavel, E., Marquering, H. A., & Majoie, C. B. L. M. (2023). Bifurcation occlusions and endovascular treatment outcome in acute ischemic stroke. Journal of Neurointerventional Surgery, 15(4), 355-362. https://doi.org/10.1136/neurintsurg-2021-018560
- Olthuis, S. G. H., Hinsenveld, W. H., Pinckaers, F. M. E., Amini, M., Lingsma, H. F., Staals, J., Schreuder, T. H. C. M. L., Schonewille, W. J., Yo, L. S. F., Roos, Y. B. W. E. M., Postma, A. A., Dippel, D. W. J., van Zwam, W. H., van Oostenbrugge, R. J., de Ridder, I. R., & MR CLEAN Registry Investigators (2023). Association between type of intervention center and outcomes after endovascular treatment for acute ischemic stroke: Results from the MR CLEAN Registry. European Stroke Journal, 8(1), 224-230. https://doi.org/10.1177/23969873221145771
- Bourcier, R., Goyal, M., Muir, K. W., Desal, H., Dippel, D. W. J., Majoie, C. B. L. M., van Zwam, W. H., Jovin, T. G., Mitchell, P. J., Demchuk, A. M., van Oostenbrugge, R. J., Brown, S. B., Campbell, B., White, P., Hill, M. D., Saver, J. L., Weimar, C., Jahan, R., Guillemin, F., ... HERMES Trialists Collaboration (2023). Risk factors of unexplained early neurological deterioration after treatment for ischemic stroke due to large vessel occlusion: a post hoc analysis of the HERMES study. Journal of Neurointerventional Surgery, 15(3), 221-226. https://doi.org/10.1136/neurintsurg-2021-018214
- Schellekens, M. M. I., Boot, E. M., Verhoeven, J. I., Ekker, M. S., van Alebeek, M. E., Brouwers, P. J. A. M., Arntz, R. M., van Dijk, G. W., Gons, R. A. R., van Uden, I. W. M., den Heijer, T., de Kort, P. L. M., de Laat, K. F., van Norden, A., Vermeer, S. E., van Zagten, M. S. G., van Oostenbrugge, R. J., Wermer, M. J., Nederkoorn, P. J., ... Tuladhar, A. M. (2023). Subacute cognitive impairment after first-ever transient ischemic attack or ischemic stroke in young adults: The ODYSSEY study. European Stroke Journal, 8(1), 283-293. https://doi.org/10.1177/23969873221132032
- Kopczak, A., Stringer, M. S., van den Brink, H., Kerkhofs, D., Blair, G. W., van Dinther, M., Onkenhout, L., Wartolowska, K. A., Thrippleton, M. J., Duering, M., Staals, J., Middeke, M., Andre, E., Norrving, B., Bousser, M. G., Mansmann, U., Rothwell, P. M., Doubal, F. N., van Oostenbrugge, R., ... SVDs@Target Investigators (2023). The EffecTs of Amlodipine and other Blood PREssure Lowering Agents on Microvascular FuncTion in Small Vessel Diseases (TREAT-SVDs) trial: Study protocol for a randomised crossover trial. European Stroke Journal, 8(1), 387-397. https://doi.org/10.1177/23969873221143570
- Sluis, W. M., Hinsenveld, W. H., Goldhoorn, R. J. B., Potters, L. H., Bruggeman, A. A. E., van der Hoorn, A., Bot, J. C. J., van Oostenbrugge, R. J., Lingsma, H. F., Hofmeijer, J., van Zwam, W. H., Majoie, C. B., van der Worp, H. B., & MR CLEAN Registry Investigators (2023). Timing and causes of death after endovascular thrombectomy in patients with acute ischemic stroke. European Stroke Journal, 8(1), 215-223. https://doi.org/10.1177/23969873221143210
- van den Kerkhof, M., Jansen, J. F. A., van Oostenbrugge, R. J., & Backes, W. H. (2023). 1D versus 3D blood flow velocity and pulsatility measurements of lenticulostriate arteries at 7T MRI. Magnetic Resonance Imaging, 96(1), 144-150. https://doi.org/10.1016/j.mri.2022.12.005
- Olthuis, S. G. H., den Hartog, S. J., van Kuijk, S. M. J., Staals, J., Benali, F., van der Leij, C., Beumer, D., Nijeholt, G. J. L. A., Uyttenboogaart, M., Martens, J. M., Van Doormaal, P. J., Vos, J. A., Emmer, B. J., Dippel, D. W. J., van Zwam, W. H., van Oostenbrugge, R. J., de Ridder, I. R., & MR CLEAN Registry Investigators (2023). Influence of the interventionist's experience on outcomes of endovascular thrombectomy in acute ischemic stroke: results from the MR CLEAN Registry. Journal of Neurointerventional Surgery, 15(2), 113-119. https://doi.org/10.1136/neurintsurg-2021-018295
- Collette, S. L., Bokkers, R. P. H., Mazuri, A., Lycklama À Nijeholt, G. J., van Oostenbrugge, R. J., LeCouffe, N. E., Benali, F., Majoie, C. B. L. M., de Groot, J. C., Luijckx, G. J. R., Uyttenboogaart, M., & MR CLEAN Registry Investigators (2023). Intra-arterial thrombolytics during endovascular thrombectomy for acute ischaemic stroke in the MR CLEAN Registry. Stroke and Vascular Neurology, 8(1), 17-25. https://doi.org/10.1136/svn-2022-001677
- Ekker, M. S., Verhoeven, J. I., Schellekens, M. M. I., Boot, E. M., van Alebeek, M. E., Brouwers, P. J. A. M., Arntz, R. M., van Dijk, G. W., Gons, R. A. R., van Uden, I. W. M., den Heijer, T., de Kort, P. L. M., de Laat, K. F., van Norden, A. G. W., Vermeer, S. E., van Zagten, M. S. G., van Oostenbrugge, R. J., Wermer, M. J. H., Nederkoorn, P. J., ... de Leeuw, F.-E. (2023). Risk Factors and Causes of Ischemic Stroke in 1322 Young Adults. Stroke, 54(2), 439-447. https://doi.org/10.1161/STROKEAHA.122.040524
- Ekker, M. S., Verhoeven, J. I., Rensink, K., Schellekens, M. M. I., Boot, E., van Alebeek, M., Brouwers, P. J. A. M., Arntz, R., van Dijk, G. W., Gons, R. A. R., van Uden, I., den Heijer, T., de Kort, P., de Laat, K., van Norden, A. G., Vermeer, S., van Zagten, M., van Oostenbrugge, R., Wermer, M. J. H., ... Leeuw, F.-E. D. (2023). Trigger Factors for Stroke in Young Adults: A Case-Crossover Study. Neurology, 100(1), E49-E61. https://doi.org/10.1212/WNL.0000000000201341
- van Dinther, M., Bennett, J., Thornton, G. D., Voorter, P. H. M., Casajus, A. E., Hughes, A., Captur, G., Holtackers, R. J., Staals, J., Backes, W. H., Bastarika, G., Jones, E. A. V., Gonzalez, A., van Oostenbrugge, R., Treibel, T. A., & CRUCIAL Consortium (2023). Evaluation of miCRovascular rarefaction in vascUlar Cognitive Impairment and heArt faiLure (CRUCIAL): Study protocol for an observational study. Cerebrovascular Diseases Extra, 13(1), 18-32. https://doi.org/10.1159/000529067
- Kuipers, S., Willemse, S. W., Greving, J. P., Bron, E. E., van Oostenbrugge, R. J., van Osch, M. J. P., Biessels, G. J., Kappelle, L. J., & Heart-Brain Connection Consortium (2023). Lower haemoglobin concentrations are associated with impaired cognition in patients with carotid artery occlusion. Cerebral Circulation - Cognition and Behavior, 5(1), Article 100169. https://doi.org/10.1016/j.cccb.2023.100169
- van Kranendonk, K. R., Kappelhof, M., Bruggeman, A. A. E., Rinkel, L. A., Treurniet, K. M., LeCouffe, N., Emmer, B. J., Coutinho, J. M., Wolff, L., van Zwam, W. H., van Oostenbrugge, R. J., van der Lugt, A., Dippel, D. W. J., Roos, Y. B. W. E. M., Marquering, H. A., Majoie, C. B. L. M., & MR CLEAN-NO IV Investigators (2023). Hemorrhage rates in patients with acute ischemic stroke treated with intravenous alteplase and thrombectomy versus thrombectomy alone. Journal of Neurointerventional Surgery, 15(E2), E262-E269. https://doi.org/10.1136/jnis-2022-019569
2022
- Mishra, A., Malik, R., Hachiya, T., Jürgenson, T., Namba, S., Posner, D. C., Kamanu, F. K., Koido, M., Le Grand, Q., Shi, M., He, Y., Georgakis, M. K., Caro, I., Krebs, K., Liaw, Y. C., Vaura, F. C., Lin, K., Winsvold, B. S., Srinivasasainagendra, V., ... van Oostenbrugge, R. J. (2022). Publisher Correction: Stroke genetics informs drug discovery and risk prediction across ancestries. Nature, 612(7938), Article E7. https://doi.org/10.1038/s41586-022-05492-5
- Kuipers, S., Greving, J. P., Brunner-La Rocca, H.-P., Gottesman, R. F., van Oostenbrugge, R. J., Williams, N. L., Jan Biessels, G., Jaap Kappelle, L., & Heart-Brain Connection Consortium (2022). Risk evaluation of cognitive impairment in patients with heart failure: A call for action. IJC Heart and Vasculature, 43, Article 101133. https://doi.org/10.1016/j.ijcha.2022.101133
- van der Steen, W., van der Ende, N. A. M., van Kranendonk, K. R., Chalos, V., Brouwer, J., van Oostenbrugge, R. J., van Zwam, W. H., van Doormaal, P. J., van Es, A. C. G. M., Majoie, C. B. L. M., van der Lugt, A., Dippel, D. W. J., Roozenbeek, B., MR CLEAN Trial, & MR CLEAN Registry Investigators (2022). Timing of symptomatic intracranial hemorrhage after endovascular stroke treatment. European Stroke Journal, 7(4), 393-401. https://doi.org/10.1177/23969873221112279
- Mishra, A., Malik, R., Hachiya, T., Jürgenson, T., Namba, S., Posner, D. C., Kamanu, F. K., Koido, M., Le Grand, Q., Shi, M., He, Y., Georgakis, M. K., Caro, I., Krebs, K., Liaw, Y. C., Vaura, F. C., Lin, K., Winsvold, B. S., Srinivasasainagendra, V., ... van Oostenbrugge, R. J. (2022). Stroke genetics informs drug discovery and risk prediction across ancestries. Nature, 611(7934), 115-123. https://doi.org/10.1038/s41586-022-05165-3
- van den Berg, S. A., Uniken Venema, S. M., Reinink, H., Hofmeijer, J., Schonewille, W. J., Miedema, I., Fransen, P. S. S., O Pruissen, D. M., Raaijmakers, T. W. M., van Dijk, G. W., de Leeuw, F.-E., van Vliet, J. A., Kwa, V. I. H., Kerkhoff, H., van 't Net, A., Boomars, R., Siegers, A., Lok, T., Caminada, K., ... MR ASAP Investigators (2022). Prehospital transdermal glyceryl trinitrate in patients with presumed acute stroke (MR ASAP): an ambulance-based, multicentre, randomised, open-label, blinded endpoint, phase 3 trial. Lancet Neurology, 21(11), 971-981. https://doi.org/10.1016/S1474-4422(22)00333-7
- Konduri, P., Bucker, A., Boers, A., Dutra, B., Samuels, N., Treurniet, K., Berkhemer, O., Yoo, A., van Zwam, W., van Oostenbrugge, R., van der Lugt, A., Dippel, D., Roos, Y., Bot, J., Majoie, C., Marquering, H., & MR CLEAN Trial Investigators (2022). Risk factors of late lesion growth after acute ischemic stroke treatment. Frontiers in Neurology, 13, Article 977608. https://doi.org/10.3389/fneur.2022.977608
- Luijten, S. P. R., Compagne, K. C. J., van Es, A. C. G. M., Roos, Y. B. W. E. M., Majoie, C. B. L. M., van Oostenbrugge, R. J., van Zwam, W. H., Dippel, D. W. J., Wolters, F. J., van der Lugt, A., Bos, D., & MR CLEAN Trial Investigators (2022). Brain atrophy and endovascular treatment effect in acute ischemic stroke: a secondary analysis of the MR CLEAN trial. International journal of stroke, 17(8), 881-888. Article 17474930211054964. https://doi.org/10.1177/17474930211054964
- van Dam-Nolen, D. H. K., Truijman, M. T. B., van der Kolk, A. G., Liem, M. I., Schreuder, F. H. B. M., Boersma, E., Daemen, M. J. A. P., Mess, W. H., van Oostenbrugge, R. J., van der Steen, A. F. W., Bos, D., Koudstaal, P. J., Nederkoorn, P. J., Hendrikse, J., van der Lugt, A., Kooi, M. E., & PARISK Study Group (2022). Carotid Plaque Characteristics Predict Recurrent Ischemic Stroke and TIA: The PARISK (Plaque At RISK) Study. JACC-Cardiovascular Imaging, 15(10), 1715-1726. https://doi.org/10.1016/j.jcmg.2022.04.003
- Kersten, C. J. B. A., Zandbergen, A. A. M., Berkhemer, O. A., Borst, J., Haalboom, M., Roos, Y. B. W. E. M., Dippel, D. W. J., van Oostenbrugge, R. J., van der Lugt, A., van Zwam, W. H., Majoie, C. B., den Hertog, H. M., & MR CLEAN Investigators (2022). Association of hyperglycemia and computed tomographic perfusion deficits in patients who underwent endovascular treatment for acute ischemic stroke caused by a proximal intracranial occlusion: A subgroup analysis of a randomized phase 3 trial (MR CLEAN). Journal of the Neurological Sciences, 440, Article 120333. https://doi.org/10.1016/j.jns.2022.120333
- Schuhmann, T., Duecker, F., Middag-van Spanje, M., Gallotto, S., van Heugten, C., Schrijnemaekers, A. C., van Oostenbrugge, R., & Sack, A. T. (2022). Transcranial alternating brain stimulation at alpha frequency reduces hemispatial neglect symptoms in stroke patients. International Journal of Clinical and Health Psychology, 22(3), Article 100326. https://doi.org/10.1016/j.ijchp.2022.100326
- van der Steen, W., van der Ende, N. A. M., van Kranendonk, K. R., Chalos, V., van Oostenbrugge, R. J., van Zwam, W. H., Roos, Y. B. W. E. M., van Doormaal, P. J., van Es, A. C. G. M., Lingsma, H. F., Majoie, C. B. L. M., van der Lugt, A., Dippel, D. W. J., Roozenbeek, B., & MR CLEAN Trial and MR CLEAN Registry Investigators (2022). Determinants of Symptomatic Intracranial Hemorrhage After Endovascular Stroke Treatment: A Retrospective Cohort Study. Stroke, 53(9), 2818-2827. https://doi.org/10.1161/STROKEAHA.121.036195
- van Dinther, M., Voorter, P. H. M., Schram, M. T., Berendschot, T. T. J. M., Houben, A. J. H. M., Webers, C. A. B., van Oostenbrugge, R. J., Backes, W. H., Staals, J., & Jansen, J. F. A. (2022). Retinal microvascular function is associated with the cerebral microcirculation as determined by intravoxel incoherent motion MRI. Journal of the Neurological Sciences, 440, Article 120359. https://doi.org/10.1016/j.jns.2022.120359
- Rudilosso, S., Chui, E., Stringer, M. S., Thrippleton, M., Chappell, F., Blair, G., GarcÃa, D. J., Doubal, F., Hamilton, I., Kopczak, A., Ingrish, M., Kerkhofs, D., Backes, W. H., Staals, J., van Oostenbrugge, R., Duering, M., Dichgans, M., Wardlaw, J. M., & SVDs@Target Investigators (2022). Prevalence and Significance of the Vessel-Cluster Sign on Susceptibility-Weighted Imaging in Patients With Severe Small Vessel Disease. Neurology, 99(5), E440-E452. https://doi.org/10.1212/WNL.0000000000200614
- Pirson, F. A. V. A., Boodt, N., Brouwer, J., Bruggeman, A. A. E., Hinsenveld, W. H., Staals, J., van Zwam, W. H., van der Leij, C., Brans, R. J. B., Majoie, C. B. L. M., Dippel, D. W. J., van der Lugt, A., Schonewille, W. J., van Oostenbrugge, R. J., & MR CLEAN Registry Investigators (2022). Etiology of Large Vessel Occlusion Posterior Circulation Stroke: Results of the MR CLEAN Registry. Stroke, 53(8), 2468-2477. https://doi.org/10.1161/strokeaha.121.038054
- Tolhuisen, M. L., Hoving, J. W., Koopman, M. S., Kappelhof, M., van Voorst, H., Bruggeman, A. E., Demchuck, A. M., Dippel, D. W. J., Emmer, B. J., Bracard, S., Guillemin, F., van Oostenbrugge, R. J., Mitchell, P. J., van Zwam, W. H., Hill, M. D., Roos, Y. B. W. E. M., Jovin, T. G., Berkhemer, O. A., Campbell, B. C. V., ... HERMES Investigators (2022). Outcome Prediction Based on Automatically Extracted Infarct Core Image Features in Patients with Acute Ischemic Stroke. Diagnostics, 12(8), Article 1786. https://doi.org/10.3390/diagnostics12081786
- Compagne, K. C. J., Kappelhof, M., Hinsenveld, W. H., Brouwer, J., Goldhoorn, R.-J. B., Uyttenboogaart, M., Bokkers, R. P. H., Schonewille, W. J., Martens, J. M., Hofmeijer, J., van der Worp, H. B., Lo, R. T. H., Keizer, K., Yo, L. S. F., Lycklama À Nijeholt, G. J., den Hertog, H. M., Sturm, E. J. C., Brouwers, P. J. A. M., van Walderveen, M. A. A., ... MR CLEAN Registry Investigators (2022). Improvements in Endovascular Treatment for Acute Ischemic Stroke: A Longitudinal Study in the MR CLEAN Registry. Stroke, 53(6), 1863-1872. https://doi.org/10.1161/STROKEAHA.121.034919
- Bruggeman, A. A. E., Brouwer, J., Arrarte Terreros, N., Boodt, N., den Hartog, S. J., Pirson, F. A. V., Beenen, L. F. M., van Doormaal, P.-J., van Oostenbrugge, R. J., Staals, J., van Zwam, W. H., Schonewille, W. J., Langezaal, L. C. M., Vos, J.-A., van der Lugt, A., Dippel, D. W. J., Coutinho, J. M., Roos, Y. B. W. E. M., Marquering, H. A., ... Majoie, C. B. L. M. (2022). Thrombus Imaging Characteristics and Outcomes in Posterior Circulation Stroke Patients Treated With EVT. Stroke: vascular and interventional neurology, 2(3), Article e000333. https://doi.org/10.1161/SVIN.121.000333
- van Dinther, M., Voorter, P. H. M., Jansen, J. F. A., Jones, E. A. V., van Oostenbrugge, R. J., Staals, J., & Backes, W. H. (2022). Assessment of microvascular rarefaction in human brain disorders using physiological magnetic resonance imaging. Journal of Cerebral Blood Flow and Metabolism, 42(5), 718-737. Article 0271678X221076557. https://doi.org/10.1177/0271678X221076557
- Amini, M., van Leeuwen, N., Eijkenaar, F., van de Graaf, R., Samuels, N., van Oostenbrugge, R., van den Wijngaard, I. R., van Doormaal, P. J., Roos, Y. B. W. E. M., Majoie, C., Roozenbeek, B., Dippel, D., Burke, J., Lingsma, H. F., & MR CLEAN Registry Investigators (2022). Estimation of treatment effects in observational stroke care data: comparison of statistical approaches. BMC Medical Research Methodology, 22(1), Article 103. https://doi.org/10.1186/s12874-022-01590-0
- van der Steen, W., van de Graaf, R. A., Chalos, V., Lingsma, H. F., van Doormaal, P. J., Coutinho, J. M., Emmer, B. J., de Ridder, I., van Zwam, W., van der Worp, H. B., van der Schaaf, I., Gons, R. A. R., Yo, L. S. F., Boiten, J., van den Wijngaard, I., Hofmeijer, J., Martens, J., Schonewille, W., Vos, J. A., ... MR CLEAN-MED investigators (2022). Safety and efficacy of aspirin, unfractionated heparin, both, or neither during endovascular stroke treatment (MR CLEAN-MED): an open-label, multicentre, randomised controlled trial. Lancet, 399(10329), 1059-1069. https://doi.org/10.1016/S0140-6736(22)00014-9
- Peeters, M. T. J., Vroman, F., Schreuder, TAHCML., van Oostenbrugge, R. J., & Staals, J. (2022). Decrease in incidence of oral anticoagulant-related intracerebral hemorrhage over the past decade in the Netherlands. European Stroke Journal, 7(1), 20-27. Article 23969873211062011. https://doi.org/10.1177/23969873211062011
- Bernsen, M. L. E., Bruggeman, A. A. E., Brouwer, J., Emmer, B. J., Majoie, C. B. L. M., Coutinho, J. M., Goldhoorn, R.-J. B., van Oostenbrugge, R. J., van Zwam, W. H., van der Leij, C., Schonewille, W. J., Martens, J. M., Hofmeijer, J., & MR CLEAN Registry Investigators (2022). Aspiration Versus Stent Retriever Thrombectomy for Posterior Circulation Stroke. Stroke, 53(3), 749-757. https://doi.org/10.1161/strokeaha.121.034926
- van den Berg, L. A., Berkhemer, O. A., Fransen, P. S. S., Beumer, D., Lingsma, H., Majoie, C. B. M., Dippel, D. W. J., van der Lugt, A., van Oostenbrugge, R. J., van Zwam, W. H., Roos, Y. B., Dijkgraaf, M. G. W., & MR CLEAN Investigators (2022). Economic Evaluation of Endovascular Treatment for Acute Ischemic Stroke. Stroke, 53(3), 968-975. Article STROKEAHA121034599. https://doi.org/10.1161/strokeaha.121.034599
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