• 2020
    • Lisan, Q., van Sloten, T., Climie, R. E., Boutouyrie, P., Guibout, C., Thomas, F., Danchin, N., Jouven, X., & Empana, J.-P. (2020). Sleep apnoea is associated with hearing impairment: The Paris prospective study 3. Clinical Otolaryngology, 45(5), 681-686. https://doi.org/10.1111/coa.13557
    • Hop, P. J., Luijk, R., Daxinger, L., van Iterson, M., Dekkers, K. F., Jansen, R., van Meurs, J. B. J., 't Hoen, P. A. C., Ikram, M. A., van Greevenbroek, M. M. J., Boomsma, D., Slagboom, P. E., Veldink, J. H., van Zwet, E. W., Heijmans, B. T., & BIOS Consortium (2020). Genome-wide identification of genes regulating DNA methylation using genetic anchors for causal inference. Genome Biology, 21(1), Article 220. https://doi.org/10.1186/s13059-020-02114-z
    • Geraets, A. F. J., van Agtmaal, M. J. M., Stehouwer, C. D. A., Sörensen, B. M., Berendschot, T. T. J. M., Webers, C. A. B., Schaper, N. C., Henry, R. M. A., van der Kallen, C. J. H., Eussen, S. J. P. M., Koster, A., van Sloten, T. T., Köhler, S., Schram, M. T., & Houben, A. J. H. M. (2020). Association of Markers of Microvascular Dysfunction With Prevalent and Incident Depressive Symptoms: The Maastricht Study. Hypertension, 76(2), 342-349. https://doi.org/10.1161/HYPERTENSIONAHA.120.15260
    • Zhou, T. L., Rensma, S. P., van der Heide, F. C. T., Henry, R. M. A., Kroon, A. A., Houben, A. J. H. M., Jansen, J. F. A., Backes, W. H., Berendschot, T. T. J. M., Schouten, J. S. A. G., van Dongen, M. C. J. M., Eussen, S. J. P. M., Dagnelie, P. C., Webers, C. A. B., Schram, M. T., Schalkwijk, C. G., van Sloten, T. T., & Stehouwer, C. D. A. (2020). Blood pressure variability and microvascular dysfunction: the Maastricht Study. Journal of Hypertension, 38(8), 1541-1550. https://doi.org/10.1097/HJH.0000000000002444
    • Vergoossen, L. W. M., Jansen, J. F. A., Backes, W. H., & Schram, M. T. (2020). Cardiometabolic determinants of early and advanced brain alterations: Insights from conventional and novel MRI techniques. Neuroscience and Biobehavioral Reviews, 115, 308-320. https://doi.org/10.1016/j.neubiorev.2020.04.001
    • van der Velde, J. H. P. M., Koster, A., Strotmeyer, E. S., Mess, W. H., Hilkman, D., Reulen, J. P. H., Stehouwer, C. D. A., Henry, R. M. A., Schram, M. T., van der Kallen, C. J. H., Schalkwijk, C. G., Savelberg, H. H. C. M., & Schaper, N. C. (2020). Cardiometabolic risk factors as determinants of peripheral nerve function: the Maastricht Study. Diabetologia, 63(8), 1648-1658. https://doi.org/10.1007/s00125-020-05194-5
    • Vangrieken, P., Vanterpool, S. F., van Schooten, F. J., Al-Nasiry, S., Andriessen, P., Degreef, E., Alfer, J., Kramer, B. W., & von Rango, U. (2020). Histological villous maturation in placentas of complicated pregnancies. Histology and Histopathology, 35(8), 849-862. https://doi.org/10.14670/HH-18-205
    • Pappaccogli, M., Prejbisz, A., Ciurica, S., Bruno, R. M., Aniszczuk-Hybiak, A., Bracalente, I., De Backer, T., Debieve, F., Delmotte, P., Di Monaco, S., Jarraya, F., Gordin, D., Kosinski, P., Kroon, A. A., Maas, A. H. E. M., Marcon, D., Minuz, P., Montagud-Marrahi, E., Pasquet, A., ... Persu, A. (2020). Pregnancy-Related Complications in Patients With Fibromuscular Dysplasia: A Report From the European/International Fibromuscular Dysplasia Registry. Hypertension, 76(2), 545-553. https://doi.org/10.1161/hypertensionaha.120.15349
    • De Clerck, E. E. B., Schouten, J. S. A. G., Berendschot, T. T. J. M., Koolschijn, R. S., Nuijts, R. M. M. A., Schram, M. T., Schaper, N. C., Henry, R. M. A., Dagnelie, P. C., Ruggeri, A., Guimarães, P., Stehouwer, C. D. A., & Webers, C. A. B. (2020). Reduced corneal nerve fibre length in prediabetes and type 2 diabetes: The Maastricht Study. Acta Ophthalmologica, 98(5), 485-491. https://doi.org/10.1111/aos.14359
    • De With, R. R., Erkuner, O., Rienstra, M., Nguyen, B.-O., Korver, F. W. J., Linz, D., Ten, H. C., Spronk, H., Kroon, A. A., Maass, A. H., Blaauw, Y., Tieleman, R. G., Hemels, M. E. W., de Groot, J. R., Elvan, A., de Melis, M., Scheerder, C. O. S., Al-Jazairi, M. I. H., Schotten, U., ... RACE V Investigators (2020). Temporal patterns and short-term progression of paroxysmal atrial fibrillation data from RACE V. EP Europace, 22(8), 1162-1172. https://doi.org/10.1093/europace/euaa123
    • Rensma, S. P., van Sloten, T. T., Ding, J., Sigurdsson, S., Stehouwer, C. D. A., Gudnason, V., & Launer, L. J. (2020). Type 2 Diabetes, Change in Depressive Symptoms Over Time, and Cerebral Small Vessel Disease: Longitudinal Data of the AGES-Reykjavik Study. Diabetes Care, 43(8), 1781-1787. https://doi.org/10.2337/dc19-2437
    • Kerkhofs, D., van Hagen, B. T., Milanova, I. V., Schell, K. J., van Essen, H., Wijnands, E., Goossens, P., Blankesteijn, W. M., Unger, T., Prickaerts, J., Biessen, E. A., van Oostenbrugge, R. J., & Foulquier, S. (2020). Pharmacological depletion of microglia and perivascular macrophages prevents Vascular Cognitive Impairment in Ang II-induced hypertension. Theranostics, 10(21), 9512-9527. https://doi.org/10.7150/thno.44394
    • Latten, G., Hensgens, K., de Bont, E. G. P. M., Muris, J. W. M., Cals, J. W. L., & Stassen, P. (2020). How well are sepsis and a sense of urgency documented throughout the acute care chain in the Netherlands? A prospective, observational study. BMJ Open, 10(7), e036276. Article 036276. https://doi.org/10.1136/bmjopen-2019-036276
    • Zwakenberg, S. R., de Jong, P. A., Hendriks, E. J., Westerink, J., Spiering, W., de Borst, G. J., Cramer, M. J., Bartstra, J. W., Doesburg, T., Rutters, F., van der Heijden, A. A., Schalkwijk, C., Schurgers, L. J., van der Schouw, Y. T., Beulens, J. W. J., & SMART Study Grp (2020). Intimal and medial calcification in relation to cardiovascular risk factors. PLOS ONE, 15(7), Article 0235228. https://doi.org/10.1371/journal.pone.0235228
    • Zelis, N., Huisman, S. E., Mauritz, A. N., Buijs, J., de Leeuw, P. W., & Stassen, P. M. (2020). Concerns of older patients and their caregivers in the emergency department. PLOS ONE, 15(7), Article 0235708. https://doi.org/10.1371/journal.pone.0235708
    • Gietema, H. A., Zelis, N., Nobel, J. M., Lambriks, L. J. G., van Alphen, L. B., Lashof, A. M. L. O., Wildberger, J. E., Nelissen, I. C., & Stassen, P. M. (2020). CT in relation to RT-PCR in diagnosing COVID-19 in The Netherlands: A prospective study. PLOS ONE, 15(7), Article e0235844. https://doi.org/10.1371/journal.pone.0235844
    • Linssen, P. B. C., Brunner-La Rocca, H.-P., Schalkwijk, C. G., Beulens, J. W. J., Elders, P. J. M., Van der Heijden, A. A., Slieker, R. C., Stehouwer, C. D. A., & Henry, R. M. A. (2020). Serum Matrix Metalloproteinases and Left Atrial Remodeling-The Hoorn Study. International journal of molecular sciences, 21(14), Article 4944. https://doi.org/10.3390/ijms21144944
    • Zelis, N., Buijs, J., de Leeuw, P. W., van Kuijk, S. M. J., & Stassen, P. M. (2020). A new simplified model for predicting 30-day mortality in older medical emergency department patients: The rise up score. European journal of internal medicine, 77, 36-43. https://doi.org/10.1016/j.ejim.2020.02.021
    • Tofte, N., Vogelzangs, N., Mook-Kanamori, D., Brahimaj, A., Nano, J., Ahmadizar, F., van Dijk, K. W., Frimodt-Moller, M., Arts, I., Beulens, J. W. J., Rutters, F., van der Heijden, A. A., Kavousi, M., Stehouwer, C. D. A., Nijpels, G., van Greevenbroek, M. M. J., van der Kallen, C. J. H., Rossing, P., Ahluwalia, T. S., & 't Hart, L. M. (2020). Plasma Metabolomics Identifies Markers of Impaired Renal Function: A Meta-analysis of 3089 Persons with Type 2 Diabetes. Journal of Clinical Endocrinology & Metabolism, 105(7), 2275-2287. https://doi.org/10.1210/clinem/dgaa173
    • Li, W., Schram, M. T., Berendschot, T. T. J. M., Webers, C. A. B., Kroon, A. A., van der Kallen, C. J. H., Henry, R. M. A., Schaper, N. C., Huang, F., Dashtbozorg, B., Tan, T., Zhang, J., Abbasi-Sureshjani, S., Ter Haar Romeny, B. M., Stehouwer, C. D. A., & Houben, A. J. H. M. (2020). Type 2 diabetes and HbA1c are independently associated with wider retinal arterioles: the Maastricht study. Diabetologia, 63(7), 1408-1417. https://doi.org/10.1007/s00125-020-05146-z
    • Folcarelli, R., Tinnevelt, G. H., Hilvering, B., Wouters, K., van Staveren, S., Postma, G. J., Vrisekoop, N., Buydens, L. M. C., Koenderman, L., & Jansen, J. J. (2020). Multi-set Pre-processing of Multicolor Flow Cytometry Data. Scientific Reports, 10(1), Article 9716. https://doi.org/10.1038/s41598-020-66195-3
    • Linssen, P. B. C., Veugen, M. G. J., Henry, R. M. A., van Der Kallen, C. J. H., Kroon, A. A., Schram, M. T., Brunner-La Rocca, H.-P., & Stehouwer, C. D. A. (2020). Associations of (pre)diabetes with right ventricular and atrial structure and function: the Maastricht Study. Cardiovascular Diabetology, 19(1), Article 88. https://doi.org/10.1186/s12933-020-01055-y
    • Consolazio, D., Koster, A., Sarti, S., Schram, M. T., Stehouwer, C. D. A., Timmermans, E. J., Wesselius, A., & Bosma, H. (2020). Neighbourhood property value and type 2 diabetes mellitus in the Maastricht study: A multilevel study. PLOS ONE, 15(6), Article 0234324. https://doi.org/10.1371/journal.pone.0234324
    • den Biggelaar, L. J. C. J., Sep, S. J. S., Mari, A., Ferrannini, E., van Dongen, M. C. J. M., Wijckmans, N. E. G., Schram, M. T., van der Kallen, C. J., Schaper, N., Henry, R. M. A., van Greevenbroek, M. M., Stehouwer, C. D. A., & Eussen, S. J. P. M. (2020). Association of artificially sweetened and sugar-sweetened soft drinks with β-cell function, insulin sensitivity, and type 2 diabetes: the Maastricht Study. European Journal of Nutrition, 59(4), 1717-1727. https://doi.org/10.1007/s00394-019-02026-0
    • Martens, R. J. H., Henry, R. M. A., Bekers, O., Dagnelie, P. C., van Dongen, M. C. J. M., Eussen, S. J. P. M., van Greevenbroek, M., Kroon, A. A., Stehouwer, C. D. A., Wesselius, A., Meex, S. J. R., & Kooman, J. P. (2020). Associations of 24-Hour Urinary Sodium and Potassium Excretion with Cardiac Biomarkers: The Maastricht Study. Journal of Nutrition, 150(6), 1413-1424. https://doi.org/10.1093/jn/nxaa080
    • Rensma, S. P., Stehouwer, C. D. A., Van Boxtel, M. P. J., Houben, A. J. H. M., Berendschot, T. T. J. M., Jansen, J. F. A., Schalkwijk, C. G., Verhey, F. R. J., Kroon, A. A., Henry, R. M. A., Backes, W. H., Dagnelie, P. C., van Dongen, M. C. J. M., Eussen, S. J. P. M., Bosma, H., Köhler, S., Reesink, K. D., Schram, M. T., & van Sloten, T. T. (2020). Associations of Arterial Stiffness With Cognitive Performance, and the Role of Microvascular Dysfunction: The Maastricht Study. Hypertension, 75(6), 1607-1614. https://doi.org/10.1161/hypertensionaha.119.14307
    • Vulser, H., Lemogne, C., Boutouyrie, P., Cote, F., Perier, M.-C., Van Sloten, T., Hoertel, N., Danchin, N., Limosin, F., Jouven, X., & Empana, J.-P. (2020). Depression, antidepressants and low hemoglobin level in the Paris Prospective Study III: A cross-sectional analysis. Preventive Medicine, 135, Article 106050. https://doi.org/10.1016/j.ypmed.2020.106050
    • Simons, N., Debray, F.-G., Schaper, N. C., Feskens, E. J. M., Hollak, C. E. M., Bons, J. A. P., Bierau, J., Houben, A. J. H. M., Schalkwijk, C. G., Stehouwer, C. D. A., Cassiman, D., & Brouwers, M. C. G. J. (2020). Kidney and vascular function in adult patients with hereditary fructose intolerance. Molecular Genetics and Metabolism Reports, 23, Article 100600. https://doi.org/10.1016/j.ymgmr.2020.100600
    • Vogelzangs, N., van der Kallen, C. J. H., van Greevenbroek, M. M. J., van der Kolk, B. W., Jocken, J. W. E., Goossens, G. H., Schaper, N. C., Henry, R. M. A., Eussen, S. J. P. M., Valsesia, A., Hankemeier, T., Astrup, A., Saris, W. H. M., Stehouwer, C. D. A., Blaak, E. E., Arts, I. C. W., & CODAM study (2020). Metabolic profiling of tissue-specific insulin resistance in human obesity: results from the Diogenes study and the Maastricht Study. International Journal of Obesity, 44(6), 1376-1386. https://doi.org/10.1038/s41366-020-0565-z
    • Stassen, P. M., & Cals, J. W. L. (2020). Flashmobstudies: wetenschap in een flits. Nederlands Tijdschrift voor Geneeskunde, 164, Article D4736. https://www.ntvg.nl/artikelen/flashmobstudies-wetenschap-een-flits
    • Foreman, Y. D., Brouwers, M. C. G. J., van der Kallen, C. J. H., Pagen, D. M. E., van Greevenbroek, M. M. J., Henry, R. M. A., Koster, A., Wesselius, A., Schaper, N. C., & Stehouwer, C. D. A. (2020). Glucose Variability Assessed with Continuous Glucose Monitoring: Reliability, Reference Values, and Correlations with Established Glycemic Indices-The Maastricht Study. Diabetes Technology & Therapeutics, 22(5), 395-403. https://doi.org/10.1089/dia.2019.0385
    • Haijes, H. A., Molema, F., Langeveld, M., Janssen, M. C., Bosch, A. M., van Spronsen, F., Mulder, M. F., Verhoeven-Duif, N. M., Jans, J. J. M., van der Ploeg, A. T., Wagenmakers, M. A., Rubio-Gozalbo, M. E., Brouwers, M. C. G. J., de Vries, M. C., Langendonk, J. G., Williams, M., & van Hasselt, P. M. (2020). Retrospective evaluation of the Dutch pre-newborn screening cohort for propionic acidemia and isolated methylmalonic acidemia: What to aim, expect, and evaluate from newborn screening?Journal of Inherited Metabolic Disease, 43(3), 424-437. https://doi.org/10.1002/jimd.12193
    • Xin, Y., Hertle, E., van der Kallen, C. J. H., Schalkwijk, C. G., Stehouwer, C. D. A., & van Greevenbroek, M. M. J. (2020). Associations of dicarbonyl stress with complement activation: the CODAM study. Diabetologia, 63(5), 1032-1042. https://doi.org/10.1007/s00125-020-05098-4
    • Coopmans, C., Zhou, T. L., Henry, R. M. A., Heijman, J., Schaper, N. C., Koster, A., Schram, M. T., van der Kallen, C. J. H., Wesselius, A., den Engelsman, R. J. A., Crijns, H. J. G. M., & Stehouwer, C. D. A. (2020). Both Prediabetes and Type 2 Diabetes Are Associated With Lower Heart Rate Variability: The Maastricht Study. Diabetes Care, 43(5), 1126-1133. https://doi.org/10.2337/dc19-2367
    • Sorensen, B. M., van der Heide, F. C. T., Houben, A. J. H. M., Koster, A., Berendschot, T. T. J. M., Schouten, J. S. A. G., Kroon, A. A., van der Kallen, C. J. H., Henry, R. M. A., van Dongen, M. C. J. M., Eussen, S. J. P. M., Savelberg, H. H. C. M., van der Berg, J. D., Schaper, N. C., Schram, M. T., & Stehouwer, C. D. A. (2020). Higher levels of daily physical activity are associated with better skin microvascular function in type 2 diabetes-The Maastricht Study. Microcirculation, 27(4), Article 12611. https://doi.org/10.1111/micc.12611
    • Van den Eynde, M. D. G., Streese, L., Houben, A. J. H. M., Stehouwer, C. D. A., Scheijen, J. L. J. M., Schalkwijk, C. G., Hanssen, N. M. J., & Hanssen, H. (2020). Physical activity and markers of glycation in older individuals: data from a combined cross-sectional and randomized controlled trial (EXAMIN AGE). Clinical Science, 134(9), 1095-1105. https://doi.org/10.1042/CS20200255
    • Buziau, A. M., Schalkwijk, C. G., Stehouwer, C. D. A., Tolan, D. R., & Brouwers, M. C. G. J. (2020). Recent advances in the pathogenesis of hereditary fructose intolerance: implications for its treatment and the understanding of fructose-induced non-alcoholic fatty liver disease. Cellular and Molecular Life Sciences, 77(9), 1709-1719. https://doi.org/10.1007/s00018-019-03348-2
    • Simons, N., Bijnen, M., Wouters, K. A. M., Rensen, S. S., Beulens, J. W. J., van Greevenbroek, M. M. J., 't Hart, L. M., Greve, J. W. M., van der Kallen, C. J. H., Schaper, N. C., Schalkwijk, C. G., Stehouwer, C. D. A., & Brouwers, M. C. G. J. (2020). The endothelial function biomarker soluble E-selectin is associated with nonalcoholic fatty liver disease. Liver International, 40(5), 1079-1088. https://doi.org/10.1111/liv.14384
    • Roumans, K. H. M., Lindeboom, L., Veeraiah, P., Remie, C. M. E., Phielix, E., Havekes, B., Bruls, Y. M. H., Brouwers, M. C. G. J., Ståhlman, M., Alssema, M., Peters, H. P. F., de Mutsert, R., Staels, B., Taskinen, M.-R., Borén, J., Schrauwen, P., & Schrauwen-Hinderling, V. B. (2020). Hepatic saturated fatty acid fraction is associated with de novo lipogenesis and hepatic insulin resistance. Nature Communications, 11(1), Article 1891. https://doi.org/10.1038/s41467-020-15684-0
    • Sari, G., Meester, E. J., van der Zee, L. C., Wouters, K., van Lennep, J. R., Peppelenbosch, M., Boonstra, A., Van der Heiden, K., Mulder, M. M. T., & Vanwolleghem, T. (2020). A mouse model of humanized liver shows a human-like lipid profile, but does not form atherosclerotic plaque after western type diet. Biochemical and Biophysical Research Communications, 524(2), 510-515. https://doi.org/10.1016/j.bbrc.2020.01.067
    • van Sloten, T. T., Sedaghat, S., Carnethon, M. R., Launer, L. J., & Stehouwer, C. D. A. (2020). Cerebral microvascular complications of type 2 diabetes: stroke, cognitive dysfunction, and depression. The Lancet Diabetes & Endocrinology, 8(4), 325-336. https://doi.org/10.1016/S2213-8587(19)30405-X
    • Vrolijk, M. F., van Essen, H., Opperhuizen, A., Bast, A., & Janssen, B. J. (2020). Haemodynamic effects of the flavonoid quercetin in rats revisited. British Journal of Pharmacology, 177(8), 1841-1852. https://doi.org/10.1111/bph.14955
    • Marcoccia, A., Klein-Weigel, P. F., Gschwandtner, M. E., Wautrecht, J.-C., Matuska, J., Rother, U., & Houben, A. J. H. M. (2020). Microcirculatory assessment of vascular diseases. Vasa-European Journal of Vascular Medicine, 49(3), 175-186. https://doi.org/10.1024/0301-1526/a000851
    • Zhang, C., Couppe, C., Scheijen, J. L. J. M., Schalkwijk, C. G., Kjaer, M., Magnusson, S. P., & Svensson, R. B. (2020). Regional collagen turnover and composition of the human patellar tendon. Journal of Applied Physiology, 128(4), 884-891. https://doi.org/10.1152/japplphysiol.00030.2020
    • Stehouwer, C., van der Kallen, C., van Greevenbroek, M., & BBMRI Metabolomics Consortium (2020). Author Correction: Heritability estimates for 361 blood metabolites across 40 genome-wide association studies. Nature Communications, 11(1), Article 1702. https://doi.org/10.1038/s41467-020-15276-y
    • Schutten, M. T. J., Kusters, Y. H. A. M., Houben, A. J. H. M., Niessen, H. E., Roodt, J. O., Scheijen, J. L. J. M., van de Waardenburg, M. P., Schalkwijk, C. G., de Leeuw, P. W., & Stehouwer, C. D. A. (2020). Glucocorticoids affect metabolic but not muscle microvascular insulin sensitivity following high versus low salt intake. JCI INSIGHT, 5(6), Article 127530. https://doi.org/10.1172/jci.insight.127530
    • Bot, M., Milaneschi, Y., Al-Shehri, T., Amin, N., Garmaeva, S., Onderwater, G. L. J., Pool, R., Thesing, C. S., Vijfhuizen, L. S., Vogelzangs, N., Arts, I. C. W., Demirkan, A., van Duijn, C., van Greevenbroek, M., van der Kallen, C. J. H., Koehler, S., Ligthart, L., van den Maagdenberg, M. J. M., Mook-Kanamori, D. O., ... BBMRI-NL Metabolomics Consortium (2020). Metabolomics Profile in Depression: A Pooled Analysis of 230 Metabolic Markers in 5283 Cases With Depression and 10,145 Controls. Biological Psychiatry, 87(5), 409-418. https://doi.org/10.1016/j.biopsych.2019.08.016
    • Pouwer, F., Schram, M. T., Iversen, M. M., Nouwen, A., & Holt, R. I. G. (2020). How 25 years of psychosocial research has contributed to a better understanding of the links between depression and diabetes. Diabetic Medicine, 37(3), 383-392. https://doi.org/10.1111/dme.14227
    • Vangrieken, P., Al-Nasiry, S., Bast, A., Leermakers, P. A., Tulen, C. B. M., Janssen, G. M. J., Schiffers, P. M. H., van Schooten, F. J., & Remels, A. H. V. (2020). Placental Mitochondrial Abnormalities Upon Hypoxia; The Cause of Placental Oxidative Stress?Reproductive Sciences, 27(SUPPL 1), 268A-268A.
    • Bellier, J., Nokin, M. J., Caprasse, M., Tiamiou, A., Blomme, A., Scheijen, J. L., Koopmansch, B., MacKay, G. M., Chiavarina, B., Costanza, B., Rademaker, G., Durieux, F., Agirman, F., Maloujahmoum, N., Cusumano, P. G., Lovinfosse, P., Leung, H. Y., Lambert, F., Bours, V., ... Bellahcene, A. (2020). Methylglyoxal Scavengers Resensitize KRAS-Mutated Colorectal Tumors to Cetuximab. Cell Reports, 30(5), 1400-1416.e6. https://doi.org/10.1016/j.celrep.2020.01.012