Publications
- 2020
- Vogelzangs, N., van der Kallen, C. J. H., van Greevenbroek, M. M. J., van der Kolk, B. W., Jocken, J. W. E., Goossens, G. H., Schaper, N. C., Henry, R. M. A., Eussen, S. J. P. M., Valsesia, A., Hankemeier, T., Astrup, A., Saris, W. H. M., Stehouwer, C. D. A., Blaak, E. E., Arts, I. C. W., & CODAM study (2020). Metabolic profiling of tissue-specific insulin resistance in human obesity: results from the Diogenes study and the Maastricht Study. International Journal of Obesity, 44(6), 1376-1386. https://doi.org/10.1038/s41366-020-0565-z
- Stassen, P. M., & Cals, J. W. L. (2020). Flashmobstudies: wetenschap in een flits. Nederlands Tijdschrift voor Geneeskunde, 164, Article D4736. https://www.ntvg.nl/artikelen/flashmobstudies-wetenschap-een-flits
- Foreman, Y. D., Brouwers, M. C. G. J., van der Kallen, C. J. H., Pagen, D. M. E., van Greevenbroek, M. M. J., Henry, R. M. A., Koster, A., Wesselius, A., Schaper, N. C., & Stehouwer, C. D. A. (2020). Glucose Variability Assessed with Continuous Glucose Monitoring: Reliability, Reference Values, and Correlations with Established Glycemic Indices-The Maastricht Study. Diabetes Technology & Therapeutics, 22(5), 395-403. https://doi.org/10.1089/dia.2019.0385
- Haijes, H. A., Molema, F., Langeveld, M., Janssen, M. C., Bosch, A. M., van Spronsen, F., Mulder, M. F., Verhoeven-Duif, N. M., Jans, J. J. M., van der Ploeg, A. T., Wagenmakers, M. A., Rubio-Gozalbo, M. E., Brouwers, M. C. G. J., de Vries, M. C., Langendonk, J. G., Williams, M., & van Hasselt, P. M. (2020). Retrospective evaluation of the Dutch pre-newborn screening cohort for propionic acidemia and isolated methylmalonic acidemia: What to aim, expect, and evaluate from newborn screening?Journal of Inherited Metabolic Disease, 43(3), 424-437. https://doi.org/10.1002/jimd.12193
- Xin, Y., Hertle, E., van der Kallen, C. J. H., Schalkwijk, C. G., Stehouwer, C. D. A., & van Greevenbroek, M. M. J. (2020). Associations of dicarbonyl stress with complement activation: the CODAM study. Diabetologia, 63(5), 1032-1042. https://doi.org/10.1007/s00125-020-05098-4
- Coopmans, C., Zhou, T. L., Henry, R. M. A., Heijman, J., Schaper, N. C., Koster, A., Schram, M. T., van der Kallen, C. J. H., Wesselius, A., den Engelsman, R. J. A., Crijns, H. J. G. M., & Stehouwer, C. D. A. (2020). Both Prediabetes and Type 2 Diabetes Are Associated With Lower Heart Rate Variability: The Maastricht Study. Diabetes Care, 43(5), 1126-1133. https://doi.org/10.2337/dc19-2367
- Sorensen, B. M., van der Heide, F. C. T., Houben, A. J. H. M., Koster, A., Berendschot, T. T. J. M., Schouten, J. S. A. G., Kroon, A. A., van der Kallen, C. J. H., Henry, R. M. A., van Dongen, M. C. J. M., Eussen, S. J. P. M., Savelberg, H. H. C. M., van der Berg, J. D., Schaper, N. C., Schram, M. T., & Stehouwer, C. D. A. (2020). Higher levels of daily physical activity are associated with better skin microvascular function in type 2 diabetes-The Maastricht Study. Microcirculation, 27(4), Article 12611. https://doi.org/10.1111/micc.12611
- Van den Eynde, M. D. G., Streese, L., Houben, A. J. H. M., Stehouwer, C. D. A., Scheijen, J. L. J. M., Schalkwijk, C. G., Hanssen, N. M. J., & Hanssen, H. (2020). Physical activity and markers of glycation in older individuals: data from a combined cross-sectional and randomized controlled trial (EXAMIN AGE). Clinical Science, 134(9), 1095-1105. https://doi.org/10.1042/CS20200255
- Buziau, A. M., Schalkwijk, C. G., Stehouwer, C. D. A., Tolan, D. R., & Brouwers, M. C. G. J. (2020). Recent advances in the pathogenesis of hereditary fructose intolerance: implications for its treatment and the understanding of fructose-induced non-alcoholic fatty liver disease. Cellular and Molecular Life Sciences, 77(9), 1709-1719. https://doi.org/10.1007/s00018-019-03348-2
- Simons, N., Bijnen, M., Wouters, K. A. M., Rensen, S. S., Beulens, J. W. J., van Greevenbroek, M. M. J., 't Hart, L. M., Greve, J. W. M., van der Kallen, C. J. H., Schaper, N. C., Schalkwijk, C. G., Stehouwer, C. D. A., & Brouwers, M. C. G. J. (2020). The endothelial function biomarker soluble E-selectin is associated with nonalcoholic fatty liver disease. Liver International, 40(5), 1079-1088. https://doi.org/10.1111/liv.14384
- Roumans, K. H. M., Lindeboom, L., Veeraiah, P., Remie, C. M. E., Phielix, E., Havekes, B., Bruls, Y. M. H., Brouwers, M. C. G. J., Ståhlman, M., Alssema, M., Peters, H. P. F., de Mutsert, R., Staels, B., Taskinen, M.-R., Borén, J., Schrauwen, P., & Schrauwen-Hinderling, V. B. (2020). Hepatic saturated fatty acid fraction is associated with de novo lipogenesis and hepatic insulin resistance. Nature Communications, 11(1), Article 1891. https://doi.org/10.1038/s41467-020-15684-0
- Sari, G., Meester, E. J., van der Zee, L. C., Wouters, K., van Lennep, J. R., Peppelenbosch, M., Boonstra, A., Van der Heiden, K., Mulder, M. M. T., & Vanwolleghem, T. (2020). A mouse model of humanized liver shows a human-like lipid profile, but does not form atherosclerotic plaque after western type diet. Biochemical and Biophysical Research Communications, 524(2), 510-515. https://doi.org/10.1016/j.bbrc.2020.01.067
- van Sloten, T. T., Sedaghat, S., Carnethon, M. R., Launer, L. J., & Stehouwer, C. D. A. (2020). Cerebral microvascular complications of type 2 diabetes: stroke, cognitive dysfunction, and depression. The Lancet Diabetes & Endocrinology, 8(4), 325-336. https://doi.org/10.1016/S2213-8587(19)30405-X
- Vrolijk, M. F., van Essen, H., Opperhuizen, A., Bast, A., & Janssen, B. J. (2020). Haemodynamic effects of the flavonoid quercetin in rats revisited. British Journal of Pharmacology, 177(8), 1841-1852. https://doi.org/10.1111/bph.14955
- Marcoccia, A., Klein-Weigel, P. F., Gschwandtner, M. E., Wautrecht, J.-C., Matuska, J., Rother, U., & Houben, A. J. H. M. (2020). Microcirculatory assessment of vascular diseases. Vasa-European Journal of Vascular Medicine, 49(3), 175-186. https://doi.org/10.1024/0301-1526/a000851
- Zhang, C., Couppe, C., Scheijen, J. L. J. M., Schalkwijk, C. G., Kjaer, M., Magnusson, S. P., & Svensson, R. B. (2020). Regional collagen turnover and composition of the human patellar tendon. Journal of Applied Physiology, 128(4), 884-891. https://doi.org/10.1152/japplphysiol.00030.2020
- Stehouwer, C., van der Kallen, C., van Greevenbroek, M., & BBMRI Metabolomics Consortium (2020). Author Correction: Heritability estimates for 361 blood metabolites across 40 genome-wide association studies. Nature Communications, 11(1), Article 1702. https://doi.org/10.1038/s41467-020-15276-y
- Schutten, M. T. J., Kusters, Y. H. A. M., Houben, A. J. H. M., Niessen, H. E., Roodt, J. O., Scheijen, J. L. J. M., van de Waardenburg, M. P., Schalkwijk, C. G., de Leeuw, P. W., & Stehouwer, C. D. A. (2020). Glucocorticoids affect metabolic but not muscle microvascular insulin sensitivity following high versus low salt intake. JCI INSIGHT, 5(6), Article 127530. https://doi.org/10.1172/jci.insight.127530
- Bot, M., Milaneschi, Y., Al-Shehri, T., Amin, N., Garmaeva, S., Onderwater, G. L. J., Pool, R., Thesing, C. S., Vijfhuizen, L. S., Vogelzangs, N., Arts, I. C. W., Demirkan, A., van Duijn, C., van Greevenbroek, M., van der Kallen, C. J. H., Koehler, S., Ligthart, L., van den Maagdenberg, M. J. M., Mook-Kanamori, D. O., ... BBMRI-NL Metabolomics Consortium (2020). Metabolomics Profile in Depression: A Pooled Analysis of 230 Metabolic Markers in 5283 Cases With Depression and 10,145 Controls. Biological Psychiatry, 87(5), 409-418. https://doi.org/10.1016/j.biopsych.2019.08.016
- Pouwer, F., Schram, M. T., Iversen, M. M., Nouwen, A., & Holt, R. I. G. (2020). How 25 years of psychosocial research has contributed to a better understanding of the links between depression and diabetes. Diabetic Medicine, 37(3), 383-392. https://doi.org/10.1111/dme.14227
- Vangrieken, P., Al-Nasiry, S., Bast, A., Leermakers, P. A., Tulen, C. B. M., Janssen, G. M. J., Schiffers, P. M. H., van Schooten, F. J., & Remels, A. H. V. (2020). Placental Mitochondrial Abnormalities Upon Hypoxia; The Cause of Placental Oxidative Stress?Reproductive Sciences, 27(SUPPL 1), 268A-268A.
- Bellier, J., Nokin, M. J., Caprasse, M., Tiamiou, A., Blomme, A., Scheijen, J. L., Koopmansch, B., MacKay, G. M., Chiavarina, B., Costanza, B., Rademaker, G., Durieux, F., Agirman, F., Maloujahmoum, N., Cusumano, P. G., Lovinfosse, P., Leung, H. Y., Lambert, F., Bours, V., ... Bellahcene, A. (2020). Methylglyoxal Scavengers Resensitize KRAS-Mutated Colorectal Tumors to Cetuximab. Cell Reports, 30(5), 1400-1416.e6. https://doi.org/10.1016/j.celrep.2020.01.012
- Ouwens, K. G., Jansen, R., Nivard, M. G., van Dongen, J., Frieser, M. J., Hottenga, J.-J., Arindrarto, W., Claringbould, A., van Iterson, M., Mei, H., Franke, L., Heijmans, B. T., 't Hoen, P. A. C., van Meurs, J., Brooks, A., Penninx, B. W. J. H., Boomsma, D., Isaacs, A., Pool, R., ... BIOS Consortium (2020). A characterization of cis- and trans-heritability of RNA-Seq-based gene expression. European Journal of Human Genetics, 28(2), 253-263. https://doi.org/10.1038/s41431-019-0511-5
- Willemse, J. P. M. M., Meertens, L. J. E., Scheepers, H. C. J., Achten, N. M. J., Eussen, S. J., van Dongen, M. C., & Smits, L. J. M. (2020). Calcium intake from diet and supplement use during early pregnancy: the Expect study I. European Journal of Nutrition, 59(1), 167-174. https://doi.org/10.1007/s00394-019-01896-8
- Koole, J. L., Bours, M. J. L., Breedveld-Peters, J. J. L., van Roekel, E. H., van Dongen, M. C. J. M., Eussen, S. J. P. M., van Zutphen, M., van Duijnhoven, F. J. B., Boshuizen, H. C., & Weijenberg, M. P. (2020). Evaluating the Validity of a Food Frequency Questionnaire in Comparison with a 7-Day Dietary Record for Measuring Dietary Intake in a Population of Survivors of Colorectal Cancer. Journal of the Academy of Nutrition and Dietetics, 120(2), 245-257. https://doi.org/10.1016/j.jand.2019.09.008
- Brouwers, M. C. G. J., Simons, N., Stehouwer, C. D. A., & Isaacs, A. (2020). Non-alcoholic fatty liver disease and cardiovascular disease: assessing the evidence for causality. Diabetologia, 63(2), 253-260. https://doi.org/10.1007/s00125-019-05024-3
- Hagenbeek, F. A., Pool, R., van Dongen, J., Draisma, H. H. M., Jan Hottenga, J., Willemsen, G., Abdellaoui, A., Fedko, I. O., den Braber, A., Visser, P. J., de Geus, E. J. C. N., Willems van Dijk, K., Verhoeven, A., Suchiman, H. E., Beekman, M., Slagboom, P. E., van Duijn, C. M., Harms, A. C., Hankemeier, T., ... BBMRI Metabolomics Consortium (2020). Heritability estimates for 361 blood metabolites across 40 genome-wide association studies. Nature Communications, 11(1), Article 39. https://doi.org/10.1038/s41467-019-13770-6
- Liu, J., Lahousse, L., Nivard, M. G., Bot, M., Chen, L. M., van Klinken, J. B., Thesing, C. S., Beekman, M., van den Akker, E. B., Slieker, R. C., Waterham, E., van der Kallen, C. J. H., de Boer, I., Li-Gao, R. F., Vojinovic, D., Amin, N., Radjabzadeh, D., Kraaij, R., Alferink, L. J. M., ... van Duijn, C. M. (2020). Integration of epidemiologic, pharmacologic, genetic and gut microbiome data in a drug-metabolite atlas. Nature Medicine, 26(1), 110-117. https://doi.org/10.1038/s41591-019-0722-x
- Nielen, J. T. H., Driessen, J. H. M., Dagnelie, P. C., Boonen, A., van den Bemt, B., van Onzenoort, H. A. W., Neef, C., Henry, R. M. A., Burden, A. M., Sep, S. J. S., van der Kallen, C. J., Schram, M. T., Schaper, N., Stehouwer, C. D. A., Smits, L., & de Vries, F. (2020). Drug utilization in the Maastricht Study: A comparison with nationwide data. Medicine, 99(1), Article 18524. https://doi.org/10.1097/MD.0000000000018524
- van Meijel, L. A., de Vegt, F., Abbink, E. J., Rutters, F., Schram, M. T., van der Klauw, M. M., Wolffenbuttel, B. H. R., Siegelaar, S., DeVries, J. H., Sijbrands, E. J. G., Ozcan, B., de Valk, H. W., Silvius, B., Schaper, N., Stehouwer, C. D. A., Elders, P. J. M., Tack, C. J., & de Galan, B. E. (2020). High prevalence of impaired awareness of hypoglycemia and severe hypoglycemia among people with insulin-treated type 2 diabetes: The Dutch Diabetes Pearl Cohort. BMJ Open Diabetes Research & Care, 8(1), Article 000935. https://doi.org/10.1136/bmjdrc-2019-000935
- Brouwers, M. C. G. J., de Graaf, J., Simons, N., Meex, S., ten Doeschate, S., van Heertum, S., Heidemann, B., Luijten, J., de Boer, D., Schaper, N., Stehouwer, C. D. A., & van Greevenbroek, M. M. J. (2020). Incidence of type 2 diabetes in familial combined hyperlipidemia. BMJ Open Diabetes Research & Care, 8(1), Article 001107. https://doi.org/10.1136/bmjdrc-2019-001107
- Schalkwijk, C. G., & Stehouwer, C. D. A. (2020). METHYLGLYOXAL, A HIGHLY REACTIVE DICARBONYL COMPOUND, IN DIABETES, ITS VASCULAR COMPLICATIONS, AND OTHER AGE-RELATED DISEASES. Physiological Reviews, 100(1), 407-461. https://doi.org/10.1152/physrev.00001.2019
- Rensma, S. P., van Sloten, T. T., Houben, A. J. H. M., Koehler, S., van Boxtel, M. P. J., Berendschot, T. T. J. M., Jansen, J. F. A., Verhey, F. R. J., Kroon, A. A., Koster, A., Backes, W. H., Schaper, N., Dinant, G.-J., Schalkwijk, C. G., Henry, R. M. A., Wolfs, E. M. L., van Heumen, M. J. A., Schram, M. T., & Stehouwer, C. D. A. (2020). Microvascular Dysfunction Is Associated With Worse Cognitive Performance The Maastricht Study. Hypertension, 75(1), 237-245. https://doi.org/10.1161/hypertensionaha.119.13023
- Vossen, L. M., Kroon, A. A., Schurgers, L. J., & de Leeuw, P. W. (2020). Pharmacological and Nutritional Modulation of Vascular Calcification. Nutrients, 12(1), Article 100. https://doi.org/10.3390/nu12010100
- Vergoossen, L. W., Schram, M. T., de Jong, J. J., Stehouwer, C. D., Schaper, N. C., Henry, R. M., van der Kallen, C. J., Dagnelie, P. C., van Boxtel, M. P., Eussen, S. J., Backes, W. H., & Jansen, J. F. (2020). White Matter Connectivity Abnormalities in Prediabetes and Type 2 Diabetes: The Maastricht Study. Diabetes Care, 43(1), 201-208. https://doi.org/10.2337/dc19-0762
- Wetzels - van Hooijdonk, S., Bijnen, M., Wijnands, E., van de Gaar, M. J., Tan, A., Coort, S., Biessen, E., Schalkwijk, C., & Wouters, K. (2020). CD11c−MHC2low Macrophages Are a New Inflammatory and Dynamic Subset in Murine Adipose Tissue. Immunometabolism, 2(2), Article e200015. https://doi.org/10.20900/immunometab20200015
- Josefs, T., Wouters, K., Tietge, U. J. F., Annema, W., Dullaart, R. P. F., Vaisar, T., Arts, I. C. W., van der Kallen, C. J. H., Stehouwer, C. D. A., Schalkwijk, C. G., Goldberg, I. J., Fisher, E. A., & van Greevenbroek, M. M. J. (2020). High-density lipoprotein cholesterol efflux capacity is not associated with atherosclerosis and prevalence of cardiovascular outcome: The CODAM study. Journal of Clinical Lipidology, 14(1), 122-132.e4. https://doi.org/10.1016/j.jacl.2019.10.012
- de Jong, M., Oskam, M. J., Sep, S. J. S., Ozcan, B., Rutters, F., Sijbrands, E. J. G., Elders, P. J. M., Siegelaar, S. E., DeVries, J. H., Tack, C. J., Schroijen, M., de Valk, H. W., Abbink, E. J., Stehouwer, C. D. A., Jazet, I., Wolffenbuttel, B. H. R., Peters, S. A. E., Schram, M. T., & Diabet Pearl Parelsnoer Initiative (2020). Sex differences in cardiometabolic risk factors, pharmacological treatment and risk factor control in type 2 diabetes: findings from the Dutch Diabetes Pearl cohort. BMJ Open Diabetes Research & Care, 8(1), Article 001365. https://doi.org/10.1136/bmjdrc-2020-001365
- 2019
- Verbunt, R. J. A. M., & van Sloten, T. T. (2019). Steekproef: Huisarts te snel met cholesterolverlager 70-plusser. Pharmaceutisch Weekblad, 154(49), 28-29.
- Climie, R. E., Boutouyrie, P., Perier, M.-C., Chaussade, E., Plichart, M., Offredo, L., Guibout, C., van Sloten, T. T., Thomas, F., Pannier, B., Sharman, J. E., Laurent, S., Jouven, X., & Empana, J.-P. (2019). Association Between Occupational, Sport, and Leisure Related Physical Activity and Baroreflex Sensitivity The Paris Prospective Study III. Hypertension, 74(6), 1476-1483. https://doi.org/10.1161/HYPERTENSIONAHA.119.13461
- Lisan, Q., van Sloten, T. T., Lemogne, C., Offredo, L., Climie, R. E., Boutouyrie, P., Guibout, C., Thomas, F., Danchin, N., Jouven, X., & Empana, J.-P. (2019). Association of Hearing Impairment with Incident Depressive Symptoms: A Community-Based Prospective Study. American Journal of Medicine, 132(12), 1441-1449.e4. https://doi.org/10.1016/j.amjmed.2019.05.039
- van der Kolk, B. W., Kalafati, M., Adriaens, M., van Greevenbroek, M. M. J., Vogelzangs, N., Saris, W. H. M., Astrup, A., Valsesia, A., Langin, D., van der Kallen, C. J. H., Eussen, S. J. P. M., Schalkwijk, C. G., Stehouwer, C. D. A., Goossens, G. H., Arts, I. C. W., Jocken, J. W. E., Evelo, C. T., & Blaak, E. E. (2019). Subcutaneous Adipose Tissue and Systemic Inflammation Are Associated With Peripheral but Not Hepatic Insulin Resistance in Humans. Diabetes, 68(12), 2247-2258. https://doi.org/10.2337/db19-0560
- Climie, R. E., Gallo, A., Picone, D. S., Di Lascio, N., van Sloten, T. T., Guala, A., Mayer, C. C., Hametner, B., & Bruno, R. M. (2019). Measuring the Interaction Between the Macro- and Micro-Vasculature. Frontiers in Cardiovascular Medicine, 6, 1-15. Article 169. https://doi.org/10.3389/fcvm.2019.00169
- Smulders, M. W., Kietselaer, B. L. J. H., Wildberger, J. E., Dagnelie, P. C., Brunner-La Rocca, H.-P., Mingels, A. M. A., van Cauteren, Y. J. M., Theunissen, R. A. L. J., Post, M. J., Schalla, S., van Kuijk, S. M. J., Das, M., Kim, R. J., Crijns, H. J. G. M., & Bekkers, S. C. A. M. (2019). Initial Imaging-Guided Strategy Versus Routine Care in Patients With Non-ST-Segment Elevation Myocardial Infarction. Journal of the American College of Cardiology, 74(20), 2466-2477. https://doi.org/10.1016/j.jacc.2019.09.027
- Foreman, Y. D., Brouwers, M. C. G. J., Berendschot, T. T. J. M., van Dongen, M. C. J. M., Eussen, S. J. P. M., van Greevenbroek, M. M. J., Henry, R. M. A., Houben, A. J. H. M., van der Kallen, C. J. H., Kroon, A. A., Reesink, K. D., Schram, M. T., Schaper, N. C., & Stehouwer, C. D. A. (2019). The oral glucose tolerance test-derived incremental glucose peak is associated with greater arterial stiffness and maladaptive arterial remodeling: The Maastricht Study. Cardiovascular Diabetology, 18(1), Article 152. https://doi.org/10.1186/s12933-019-0950-x
- Ginsberg, C., Houben, A. J. H. M., Malhotra, R., Berendschot, T. T. J. M., Dagnelie, P. C., Kooman, J. P., Webers, C. A., Stehouwer, C. D. A., & Ix, J. H. (2019). Serum Phosphate and Microvascular Function in a Population-Based Cohort. Clinical journal of the American Society of Nephrology, 14(11), 1626-1633. https://doi.org/10.2215/CJN.02610319
- Harvey, B. M., Eussen, S. R. B. M., van Helvoort, A., & Harthoorn, L. F. (2019). Cow's Milk Allergic Infants on Elemental Formula Maintain Adequate Mineral Status Despite Using Acid-suppressive Drugs. Journal of Pediatric Gastroenterology and Nutrition, 69(5), E147-E148. https://doi.org/10.1097/MPG.0000000000002469