• 2020
    • Ouwens, K. G., Jansen, R., Nivard, M. G., van Dongen, J., Frieser, M. J., Hottenga, J.-J., Arindrarto, W., Claringbould, A., van Iterson, M., Mei, H., Franke, L., Heijmans, B. T., 't Hoen, P. A. C., van Meurs, J., Brooks, A., Penninx, B. W. J. H., Boomsma, D., Isaacs, A., Pool, R., ... BIOS Consortium (2020). A characterization of cis- and trans-heritability of RNA-Seq-based gene expression. European Journal of Human Genetics, 28(2), 253-263. https://doi.org/10.1038/s41431-019-0511-5
    • Willemse, J. P. M. M., Meertens, L. J. E., Scheepers, H. C. J., Achten, N. M. J., Eussen, S. J., van Dongen, M. C., & Smits, L. J. M. (2020). Calcium intake from diet and supplement use during early pregnancy: the Expect study I. European Journal of Nutrition, 59(1), 167-174. https://doi.org/10.1007/s00394-019-01896-8
    • Koole, J. L., Bours, M. J. L., Breedveld-Peters, J. J. L., van Roekel, E. H., van Dongen, M. C. J. M., Eussen, S. J. P. M., van Zutphen, M., van Duijnhoven, F. J. B., Boshuizen, H. C., & Weijenberg, M. P. (2020). Evaluating the Validity of a Food Frequency Questionnaire in Comparison with a 7-Day Dietary Record for Measuring Dietary Intake in a Population of Survivors of Colorectal Cancer. Journal of the Academy of Nutrition and Dietetics, 120(2), 245-257. https://doi.org/10.1016/j.jand.2019.09.008
    • Brouwers, M. C. G. J., Simons, N., Stehouwer, C. D. A., & Isaacs, A. (2020). Non-alcoholic fatty liver disease and cardiovascular disease: assessing the evidence for causality. Diabetologia, 63(2), 253-260. https://doi.org/10.1007/s00125-019-05024-3
    • Hagenbeek, F. A., Pool, R., van Dongen, J., Draisma, H. H. M., Jan Hottenga, J., Willemsen, G., Abdellaoui, A., Fedko, I. O., den Braber, A., Visser, P. J., de Geus, E. J. C. N., Willems van Dijk, K., Verhoeven, A., Suchiman, H. E., Beekman, M., Slagboom, P. E., van Duijn, C. M., Harms, A. C., Hankemeier, T., ... BBMRI Metabolomics Consortium (2020). Heritability estimates for 361 blood metabolites across 40 genome-wide association studies. Nature Communications, 11(1), Article 39. https://doi.org/10.1038/s41467-019-13770-6
    • Liu, J., Lahousse, L., Nivard, M. G., Bot, M., Chen, L. M., van Klinken, J. B., Thesing, C. S., Beekman, M., van den Akker, E. B., Slieker, R. C., Waterham, E., van der Kallen, C. J. H., de Boer, I., Li-Gao, R. F., Vojinovic, D., Amin, N., Radjabzadeh, D., Kraaij, R., Alferink, L. J. M., ... van Duijn, C. M. (2020). Integration of epidemiologic, pharmacologic, genetic and gut microbiome data in a drug-metabolite atlas. Nature Medicine, 26(1), 110-117. https://doi.org/10.1038/s41591-019-0722-x
    • Nielen, J. T. H., Driessen, J. H. M., Dagnelie, P. C., Boonen, A., van den Bemt, B., van Onzenoort, H. A. W., Neef, C., Henry, R. M. A., Burden, A. M., Sep, S. J. S., van der Kallen, C. J., Schram, M. T., Schaper, N., Stehouwer, C. D. A., Smits, L., & de Vries, F. (2020). Drug utilization in the Maastricht Study: A comparison with nationwide data. Medicine, 99(1), Article 18524. https://doi.org/10.1097/MD.0000000000018524
    • van Meijel, L. A., de Vegt, F., Abbink, E. J., Rutters, F., Schram, M. T., van der Klauw, M. M., Wolffenbuttel, B. H. R., Siegelaar, S., DeVries, J. H., Sijbrands, E. J. G., Ozcan, B., de Valk, H. W., Silvius, B., Schaper, N., Stehouwer, C. D. A., Elders, P. J. M., Tack, C. J., & de Galan, B. E. (2020). High prevalence of impaired awareness of hypoglycemia and severe hypoglycemia among people with insulin-treated type 2 diabetes: The Dutch Diabetes Pearl Cohort. BMJ Open Diabetes Research & Care, 8(1), Article 000935. https://doi.org/10.1136/bmjdrc-2019-000935
    • Brouwers, M. C. G. J., de Graaf, J., Simons, N., Meex, S., ten Doeschate, S., van Heertum, S., Heidemann, B., Luijten, J., de Boer, D., Schaper, N., Stehouwer, C. D. A., & van Greevenbroek, M. M. J. (2020). Incidence of type 2 diabetes in familial combined hyperlipidemia. BMJ Open Diabetes Research & Care, 8(1), Article 001107. https://doi.org/10.1136/bmjdrc-2019-001107
    • Schalkwijk, C. G., & Stehouwer, C. D. A. (2020). METHYLGLYOXAL, A HIGHLY REACTIVE DICARBONYL COMPOUND, IN DIABETES, ITS VASCULAR COMPLICATIONS, AND OTHER AGE-RELATED DISEASES. Physiological Reviews, 100(1), 407-461. https://doi.org/10.1152/physrev.00001.2019
    • Rensma, S. P., van Sloten, T. T., Houben, A. J. H. M., Koehler, S., van Boxtel, M. P. J., Berendschot, T. T. J. M., Jansen, J. F. A., Verhey, F. R. J., Kroon, A. A., Koster, A., Backes, W. H., Schaper, N., Dinant, G.-J., Schalkwijk, C. G., Henry, R. M. A., Wolfs, E. M. L., van Heumen, M. J. A., Schram, M. T., & Stehouwer, C. D. A. (2020). Microvascular Dysfunction Is Associated With Worse Cognitive Performance The Maastricht Study. Hypertension, 75(1), 237-245. https://doi.org/10.1161/hypertensionaha.119.13023
    • Vossen, L. M., Kroon, A. A., Schurgers, L. J., & de Leeuw, P. W. (2020). Pharmacological and Nutritional Modulation of Vascular Calcification. Nutrients, 12(1), Article 100. https://doi.org/10.3390/nu12010100
    • Vergoossen, L. W., Schram, M. T., de Jong, J. J., Stehouwer, C. D., Schaper, N. C., Henry, R. M., van der Kallen, C. J., Dagnelie, P. C., van Boxtel, M. P., Eussen, S. J., Backes, W. H., & Jansen, J. F. (2020). White Matter Connectivity Abnormalities in Prediabetes and Type 2 Diabetes: The Maastricht Study. Diabetes Care, 43(1), 201-208. https://doi.org/10.2337/dc19-0762
    • Wetzels - van Hooijdonk, S., Bijnen, M., Wijnands, E., van de Gaar, M. J., Tan, A., Coort, S., Biessen, E., Schalkwijk, C., & Wouters, K. (2020). CD11c−MHC2low Macrophages Are a New Inflammatory and Dynamic Subset in Murine Adipose Tissue. Immunometabolism, 2(2), Article e200015. https://doi.org/10.20900/immunometab20200015
    • Josefs, T., Wouters, K., Tietge, U. J. F., Annema, W., Dullaart, R. P. F., Vaisar, T., Arts, I. C. W., van der Kallen, C. J. H., Stehouwer, C. D. A., Schalkwijk, C. G., Goldberg, I. J., Fisher, E. A., & van Greevenbroek, M. M. J. (2020). High-density lipoprotein cholesterol efflux capacity is not associated with atherosclerosis and prevalence of cardiovascular outcome: The CODAM study. Journal of Clinical Lipidology, 14(1), 122-132.e4. https://doi.org/10.1016/j.jacl.2019.10.012
    • de Jong, M., Oskam, M. J., Sep, S. J. S., Ozcan, B., Rutters, F., Sijbrands, E. J. G., Elders, P. J. M., Siegelaar, S. E., DeVries, J. H., Tack, C. J., Schroijen, M., de Valk, H. W., Abbink, E. J., Stehouwer, C. D. A., Jazet, I., Wolffenbuttel, B. H. R., Peters, S. A. E., Schram, M. T., & Diabet Pearl Parelsnoer Initiative (2020). Sex differences in cardiometabolic risk factors, pharmacological treatment and risk factor control in type 2 diabetes: findings from the Dutch Diabetes Pearl cohort. BMJ Open Diabetes Research & Care, 8(1), Article 001365. https://doi.org/10.1136/bmjdrc-2020-001365
  • 2019
    • Verbunt, R. J. A. M., & van Sloten, T. T. (2019). Steekproef: Huisarts te snel met cholesterolverlager 70-plusser. Pharmaceutisch Weekblad, 154(49), 28-29.
    • Climie, R. E., Boutouyrie, P., Perier, M.-C., Chaussade, E., Plichart, M., Offredo, L., Guibout, C., van Sloten, T. T., Thomas, F., Pannier, B., Sharman, J. E., Laurent, S., Jouven, X., & Empana, J.-P. (2019). Association Between Occupational, Sport, and Leisure Related Physical Activity and Baroreflex Sensitivity The Paris Prospective Study III. Hypertension, 74(6), 1476-1483. https://doi.org/10.1161/HYPERTENSIONAHA.119.13461
    • Lisan, Q., van Sloten, T. T., Lemogne, C., Offredo, L., Climie, R. E., Boutouyrie, P., Guibout, C., Thomas, F., Danchin, N., Jouven, X., & Empana, J.-P. (2019). Association of Hearing Impairment with Incident Depressive Symptoms: A Community-Based Prospective Study. American Journal of Medicine, 132(12), 1441-1449.e4. https://doi.org/10.1016/j.amjmed.2019.05.039
    • van der Kolk, B. W., Kalafati, M., Adriaens, M., van Greevenbroek, M. M. J., Vogelzangs, N., Saris, W. H. M., Astrup, A., Valsesia, A., Langin, D., van der Kallen, C. J. H., Eussen, S. J. P. M., Schalkwijk, C. G., Stehouwer, C. D. A., Goossens, G. H., Arts, I. C. W., Jocken, J. W. E., Evelo, C. T., & Blaak, E. E. (2019). Subcutaneous Adipose Tissue and Systemic Inflammation Are Associated With Peripheral but Not Hepatic Insulin Resistance in Humans. Diabetes, 68(12), 2247-2258. https://doi.org/10.2337/db19-0560
    • Climie, R. E., Gallo, A., Picone, D. S., Di Lascio, N., van Sloten, T. T., Guala, A., Mayer, C. C., Hametner, B., & Bruno, R. M. (2019). Measuring the Interaction Between the Macro- and Micro-Vasculature. Frontiers in Cardiovascular Medicine, 6, 1-15. Article 169. https://doi.org/10.3389/fcvm.2019.00169
    • Smulders, M. W., Kietselaer, B. L. J. H., Wildberger, J. E., Dagnelie, P. C., Brunner-La Rocca, H.-P., Mingels, A. M. A., van Cauteren, Y. J. M., Theunissen, R. A. L. J., Post, M. J., Schalla, S., van Kuijk, S. M. J., Das, M., Kim, R. J., Crijns, H. J. G. M., & Bekkers, S. C. A. M. (2019). Initial Imaging-Guided Strategy Versus Routine Care in Patients With Non-ST-Segment Elevation Myocardial Infarction. Journal of the American College of Cardiology, 74(20), 2466-2477. https://doi.org/10.1016/j.jacc.2019.09.027
    • Foreman, Y. D., Brouwers, M. C. G. J., Berendschot, T. T. J. M., van Dongen, M. C. J. M., Eussen, S. J. P. M., van Greevenbroek, M. M. J., Henry, R. M. A., Houben, A. J. H. M., van der Kallen, C. J. H., Kroon, A. A., Reesink, K. D., Schram, M. T., Schaper, N. C., & Stehouwer, C. D. A. (2019). The oral glucose tolerance test-derived incremental glucose peak is associated with greater arterial stiffness and maladaptive arterial remodeling: The Maastricht Study. Cardiovascular Diabetology, 18(1), Article 152. https://doi.org/10.1186/s12933-019-0950-x
    • Ginsberg, C., Houben, A. J. H. M., Malhotra, R., Berendschot, T. T. J. M., Dagnelie, P. C., Kooman, J. P., Webers, C. A., Stehouwer, C. D. A., & Ix, J. H. (2019). Serum Phosphate and Microvascular Function in a Population-Based Cohort. Clinical journal of the American Society of Nephrology, 14(11), 1626-1633. https://doi.org/10.2215/CJN.02610319
    • Harvey, B. M., Eussen, S. R. B. M., van Helvoort, A., & Harthoorn, L. F. (2019). Cow's Milk Allergic Infants on Elemental Formula Maintain Adequate Mineral Status Despite Using Acid-suppressive Drugs. Journal of Pediatric Gastroenterology and Nutrition, 69(5), E147-E148. https://doi.org/10.1097/MPG.0000000000002469
    • Simons, N., Debray, F.-G., Schaper, N. C., Kooi, M. E., Feskens, E. J. M., Hollak, C. E. M., Lindeboom, L., Koek, G. H., Bons, J. A. P., Lefeber, D. J., Hodson, L., Schalkwijk, C. G., Stehouwer, C. D. A., Cassiman, D., & Brouwers, M. C. G. J. (2019). Patients With Aldolase B Deficiency Are Characterized by Increased Intrahepatic Triglyceride Content. Journal of Clinical Endocrinology & Metabolism, 104(11), 5056-5064. https://doi.org/10.1210/jc.2018-02795
    • Jaminon, A., Reesink, K., Kroon, A., & Schurgers, L. (2019). The Role of Vascular Smooth Muscle Cells in Arterial Remodeling: Focus on Calcification-Related Processes. International journal of molecular sciences, 20(22), Article 5694. https://doi.org/10.3390/ijms20225694
    • van Dongen, J., Zilhao, N. R., Sugden, K., Hannon, E. J., Mill, J., Caspi, A., Agnew-Blais, J., Arseneault, L., Corcoran, D. L., Moffitt, T. E., Poulton, R., Franke, B., Boomsma, D., Heijmans, B. T., t'Hoen, P. A. G., van Meurs, J., Isaacs, A., Jansen, R., Franke, L., ... BIOS Consortium (2019). Epigenome-wide Association Study of Attention-Deficit/Hyperactivity Disorder Symptoms in Adults. Biological Psychiatry, 86(8), 599-607. https://doi.org/10.1016/j.biopsych.2019.02.016
    • Sotomayor, C. G., Gomes-Neto, A. W., van Londen, M., Gans, R. O. B., Nolte, I. M., Berger, S. P., Navis, G. J., Rodrigo, R., Leuvenink, H. G. D., Schalkwijk, C. G., & Bakker, S. J. L. (2019). Circulating Advanced Glycation Endproducts and Long-Term Risk of Cardiovascular Mortality in Kidney Transplant Recipients. Clinical journal of the American Society of Nephrology, 14(10), 1512-1520. https://doi.org/10.2215/CJN.00540119
    • Latten, G. H. P., Spek, M., Muris, J. W. M., Cals, J. W. L., & Stassen, P. M. (2019). Accuracy and interobserver-agreement of respiratory rate measurements by healthcare professionals, and its effect on the outcomes of clinical prediction/diagnostic rules. PLOS ONE, 14(10), e0223155. Article 0223155. https://doi.org/10.1371/journal.pone.0223155
    • de Ritter, R., Sep, S. J. S., van der Kallen, C. J. H., Schram, M. T., Koster, A., Kroon, A. A., van Greevenbroek, M. M. J., Eussen, S. J. P. M., Dagnelie, P. C., de Jong, M., Vos, R. C., Woodward, M., Bots, M. L., Peters, S. A. E., & Stehouwer, C. D. A. (2019). Adverse differences in cardiometabolic risk factor levels between individuals with pre-diabetes and normal glucose metabolism are more pronounced in women than in men: the Maastricht Study. BMJ Open Diabetes Research & Care, 7(1), Article 000787. https://doi.org/10.1136/bmjdrc-2019-000787
    • Hausler, N., Lisan, Q., Van Sloten, T., Haba-Rubio, J., Perier, M.-C., Thomas, F., Danchin, N., Guibout, C., Boutouyrie, P., Heinzer, R., Jouven, X., Marques-Vidal, P., & Empana, J.-P. (2019). Cardiovascular health and sleep disturbances in two population-based cohort studies. Heart, 105(19), 1500-1506. https://doi.org/10.1136/heartjnl-2018-314485
    • Climie, R. E., van Sloten, T. T., Perier, M.-C., Tafflet, M., Fayosse, A., Dugravot, A., Singh-Manoux, A., & Empana, J.-P. (2019). Change in Cardiovascular Health and Incident Type 2 Diabetes and Impaired Fasting Glucose: The Whitehall II Study. Diabetes Care, 42(10), 1981-1987. https://doi.org/10.2337/dc19-0379
    • Denissen, K. F. M., Boonen, A., Nielen, J. T. H., Feitsma, A. L., van den Heuvel, E. G. H. M., Emans, P. J., Stehouwer, C. D. A., Sep, S. J. S., van Dongen, M. C. J. M., Dagnelie, P. C., & Eussen, S. J. P. M. (2019). Consumption of dairy products in relation to the presence of clinical knee osteoarthritis: The Maastricht Study. European Journal of Nutrition, 58(7), 2693-2704. https://doi.org/10.1007/s00394-018-1818-7
    • Gennip, A. C. E. V., Broers, N. J. H., Meulen, K. J. T., Canaud, B., Christiaans, M. H. L., Cornelis, T., Gelens, M. A. C. J., Hermans, M. M. H., Konings, C. J. A. M., Net, J. B. V. D., Sande, F. M. V. D., Schalkwijk, C. G., Stifft, F., Wirtz, J. J. J. M., Kooman, J. P., & Martens, R. J. H. (2019). Endothelial dysfunction and low-grade inflammation in the transition to renal replacement therapy. PLOS ONE, 14(9), Article e0222547. https://doi.org/10.1371/journal.pone.0222547
    • Ahluwalia, T. S., Tofte, N., Vogelzangs, N., Mook-Kanamori, D., Brahimaj, A., Frimodt-Moller, M., Arts, I., Beulens, J., van der Heijden, A., Stehouwer, C., Nijpels, G., van Greevenbroek, M., van der Kallen, C., Rossing, P., & 't Hart, L. M. (2019). Plasma metabolomics identifies markers of kidney function in 3,064 Europeans with type 2 diabetes. Diabetologia, 62, S456-S456.
    • Hertroijs, D. F. L., Brouwers, M. C. G. J., Elissen, A. M. J., Schaper, N. C., & Ruwaard, D. (2019). Relevant patient characteristics for estimating healthcare needs according to healthcare providers and people with type 2 diabetes: a Delphi survey. BMC Health Services Research, 19(1), Article 575. https://doi.org/10.1186/s12913-019-4371-z
    • Martens, R. J. H., Broers, N. J. H., Canaud, B., Christiaans, M. H. L., Cornelis, T., Gauly, A., Hermans, M. M. H., Konings, C. J. A. M., van Der Sande, F. M., Scheijen, J. L. J. M., Stifft, F., Wirtz, J. J. J. M., Kooman, J. P., & Schalkwijk, C. G. (2019). Relations of advanced glycation endproducts and dicarbonyls with endothelial dysfunction and low-grade inflammation in individuals with end-stage renal disease in the transition to renal replacement therapy: A cross-sectional observational study. PLOS ONE, 14(8), Article 0221058. https://doi.org/10.1371/journal.pone.0221058
    • van Der Plaat, D., Vonk, J. M., Terzikhan, N., de Jong, K., de Vries, M., La Bastide-van Gemert, S., van Diemen, C. C., Lahousse, L., Brusselle, G., Nedeljkovic, I., Amin, N., Kromhout, H., Vermeulen, R. C. H., Postma, D. S., van Duijn, C. M., Boezen, H. M., Heijmans, B. T., Hoen, P. A. C. T., van Meurs, J., ... BIOS Consortium (2019). Occupational exposure to gases/fumes and mineral dust affect DNA methylation levels of genes regulating expression. Human Molecular Genetics, 28(15), 2477-2485. https://doi.org/10.1093/hmg/ddz067
    • Mandaviya, P. R., Joehanes, R., Brody, J., Castillo-Fernandez, J. E., Dekkers, K. F., Do, A. N., Graff, M., Hänninen, I. K., Tanaka, T., de Jonge, E. A. L., Kiefte-de Jong, J. C., Absher, D. M., Aslibekyan, S., de Rijke, Y. B., Fornage, M., Hernandez, D. G., Hurme, M. A., Ikram, M. A., Jacques, P. F., ... BIOS Consortium, CHARGE Consortium Epigenetics Working Group, CHARGE Consortium Nutrition Working Group (2019). Association of dietary folate and vitamin B-12 intake with genome-wide DNA methylation in blood: a large-scale epigenome-wide association analysis in 5841 individuals. American Journal of Clinical Nutrition, 110(2), 437-450. Article 15. https://doi.org/10.1093/ajcn/nqz031
    • Maasen, K., van Greevenbroek, M. M. J., Scheijen, J. L. J. M., van der Kallen, C. J. H., Stehouwer, C. D. A., & Schalkwijk, C. G. (2019). High dietary glycemic load is associated with higher concentrations of urinary advanced glycation endproducts: the Cohort on Diabetes and Atherosclerosis Maastricht (CODAM) Study. American Journal of Clinical Nutrition, 110(2), 358-366. https://doi.org/10.1093/ajcn/nqz119
    • Porcu, E., Rueger, S., Lepik, K., Agbessi, M., Ahsan, H., Alves, I., Andiappan, A., Arindrarto, W., Awadalla, P., Battle, A., Beutner, F., Bonder, M. J., Boomsma, D., Christiansen, M., Claringbould, A., Deelen, P., Esko, T., Fave, M.-J., Franke, L., ... Kutalik, Z. (2019). Mendelian randomization integrating GWAS and eQTL data reveals genetic determinants of complex and clinical traits. Nature Communications, 10(1), Article 3300. https://doi.org/10.1038/s41467-019-10936-0
    • Tuin, J., Stassen, P. M., Bogdan, D. I., Broekroelofs, J., van Paassen, P., Tervaert, J. W. C., Sanders, J.-S., & Stegeman, C. A. (2019). Mycophenolate Mofetil Versus Cyclophosphamide for the Induction of Remission in Nonlife-Threatening Relapses of Antineutrophil Cytoplasmic Antibody-Associated Vasculitis: Randomized, Controlled Trial. Clinical journal of the American Society of Nephrology, 14(7), 1021-1028. https://doi.org/10.2215/CJN.11801018
    • Telgenkamp, I., Kusters, Y. H. A. M., Schalkwijk, C. G., Houben, A. J. H. M., Kooi, M. E., Lindeboom, L., Bons, J. A. P., Schaper, N. C., Joris, P. J., Plat, J., Mensink, R. P., Stehouwer, C. D. A., & Brouwers, M. C. G. J. (2019). Contribution of Liver Fat to Weight Loss-Induced Changes in Serum Hepatokines: A Randomized Controlled Trial. Journal of Clinical Endocrinology & Metabolism, 104(7), 2719-2727. https://doi.org/10.1210/jc.2018-02378
    • Hanssen, N. M. J., & Jandeleit-Dahm, K. A. M. (2019). Dipeptidyl peptidase-4 inhibitors and cardiovascular and renal disease in type 2 diabetes: What have we learned from the CARMELINA trial?Diabetes & Vascular Disease Research, 16(4), 303-309. https://doi.org/10.1177/1479164119842339
    • Hooijschuur, M. C. E., Ghossein-Doha, C., Kroon, A. A., De Leeuw, P. W., Zandbergen, A. A. M., Van Kuijk, S. M. J., & Spaanderman, M. E. A. (2019). Metabolic syndrome and pre-eclampsia. Ultrasound in Obstetrics & Gynecology, 54(1), 64-71. https://doi.org/10.1002/uog.20126
    • O'Donovan, S. D., Lenz, M., Goossens, G. H., van der Kallen, C. J. H., Eussen, S. J. M. P., Stehouwer, C. D. A., van Greevenbroek, M. M., Schram, M. T., Sep, S. J., Peeters, R. L. M., Blaak, E. E., van Riel, N. A. W., de Kok, T. M. C. M., & Arts, I. C. W. (2019). Improved quantification of muscle insulin sensitivity using oral glucose tolerance test data: the MISI Calculator. Scientific Reports, 9(1), Article 9388. https://doi.org/10.1038/s41598-019-45858-w