• 2022
    • Vandercappellen, E. J., Koster, A., Savelberg, H. H. C. M., Eussen, S. J. P. M., Dagnelie, P. C., Schaper, N. C., Schram, M. T., van der Kallen, C. J. H., van Greevenbroek, M. M. J., Wesselius, A., Schalkwijk, C. G., Kroon, A. A., Henry, R. M. A., & Stehouwer, C. D. A. (2022). Sedentary behaviour and physical activity are associated with biomarkers of endothelial dysfunction and low-grade inflammation-relevance for (pre)diabetes: The Maastricht Study. Diabetologia, 65(5), 777-789. https://doi.org/10.1007/s00125-022-05651-3
    • Climie, R. E., Tafflet, M., van Sloten, T., de Lauzon-Guillain, B., Bernard, J. Y., Dargent-Molina, P., Plancoulaine, S., Lioret, S., Jouven, X., Charles, M.-A., Heude, B., & Empana, J.-P. (2022). Cardiovascular Health at Age 5 Years: Distribution, Determinants, and Association With Neurodevelopment. Frontiers in pediatrics, 10, Article 827525. https://doi.org/10.3389/fped.2022.827525
    • Zeijen, V. J. M., Lafeber, M., Versmissen, J., Kroon, A. A., Boersma, E., & Daemen, J. (2022). Adequacy of blood pressure control in high-risk hypertensive patients: The DEGREE study. International Journal of Cardiology, 352, 137-143. https://doi.org/10.1016/j.ijcard.2022.02.014
    • Ottaviani, L., Pinto, V. S., Knoops, K., Wouters, K., Martins, P. A. D., & Abreu, R. (2022). Cre/Lox-Assisted Tracking Of Cardiac Intercellular Communication. Tissue Engineering, 28, S339-S340.
    • Mashnafi, S., Plat, J., Mensink, R. P., Joris, P. J., Kusters, Y. H. A. M., Houben, A. J. H. M., Stehouwer, C. D. A., Schalkwijk, C. G., & Baumgartner, S. (2022). Effects of Diet-Induced Weight Loss on Plasma Markers for Cholesterol Absorption and Synthesis: Secondary Analysis of a Randomized Trial in Abdominally Obese Men. Nutrients, 14(8), Article 1546. https://doi.org/10.3390/nu14081546
    • Simons, P. I. H. G., Cornelissen, M. E. B., Valkenburg, O., Onland-Moret, N. C., van der Schouw, Y. T., Stehouwer, C. D. A., Burgess, S., & Brouwers, M. C. G. J. (2022). Causal relationship between polycystic ovary syndrome and coronary artery disease: A Mendelian randomisation study. Clinical Endocrinology, 96(4), 599-604. https://doi.org/10.1111/cen.14593
    • Gennip, A. C. E., Sedaghat, S., Carnethon, M. R., Allen, N. B., Klein, B. E. K., Cotch, M. F., Chirinos, D. A., Stehouwer, C. D. A., & van Sloten, T. T. (2022). Retinal Microvascular Caliber and Incident Depressive Symptoms: The Multi-Ethnic Study of Atherosclerosis. American Journal of Epidemiology, 191(5), 843-855. https://doi.org/10.1093/aje/kwab255
    • Linkens, A. M. A., Houben, A. J., Niessen, P. M., Wijckmans, N., de Goei, E., Van den Eynde, M. D. G., Scheijen, J. L. J. M., Waarenburg, M., Mari, A., Berendschot, T. T. J. M., Streese, L., Hanssen, H., van Dongen, M. C. J. M., van Gool, C., Stehouwer, C. D. A., Eussen, S. J. P. M., & Schalkwijk, C. (2022). A 4-week high-AGE diet does not impair glucose metabolism and vascular function in obese individuals. JCI INSIGHT, 7(6), Article e156950. https://doi.org/10.1172/jci.insight.156950
    • Hop, P. J., Zwamborn, R. A. J., Hannon, E., Shireby, G. L., Nabais, M. F., Walker, E. M., van Rheenen, W., van Vugt, J. J. F. A., Dekker, A. M., Westeneng, H. J., Tazelaar, G. H. P., van Eijk, K. R., Moisse, M., Baird, D., Al Khleifat, A., Iacoangeli, A., Ticozzi, N., Ratti, A., Cooper-Knock, J., ... Brain MEND Consortium (2022). Genome-wide study of DNA methylation shows alterations in metabolic, inflammatory, and cholesterol pathways in ALS. Science Translational Medicine, 14(633), Article eabj0264. https://doi.org/10.1126/scitranslmed.abj0264
    • van Hulten, V., Sarodnik, C., Driessen, J. H. M., Schaper, N. C., Geusens, P. P. M. M., Webers, C. A. B., Dinant, G.-J., Ottenheijm, R. P. G., Rasmussen, N. H., Viggers, R., Stehouwer, C. D. A., van der Kallen, C. J. H., Schram, M. T., Bours, S. P. G., Dagnelie, P. C., & van den Bergh, J. P. (2022). Prevalent Morphometrically Assessed Vertebral Fractures in Individuals With Type 2 Diabetes, Prediabetes and Normal Glucose Metabolism: The Maastricht Study. Frontiers in Endocrinology, 13, Article 832977. https://doi.org/10.3389/fendo.2022.832977
    • Wu, L., Baylan, U., van der Leeden, B., Schurink, B., Roos, E., Schalkwijk, C. G., Bugiani, M., van der Valk, P., van Rossum, A. C., Zeerleder, S. S., Heunks, L. M. A., Boon, R. A., de Boer, O. J., van der Wal, A. C., Niessen, H. W. M., & Krijnen, P. A. J. (2022). Cardiac inflammation and microvascular procoagulant changes are decreased in second wave compared to first wave deceased COVID-19 patients. International Journal of Cardiology, 349, 157-165. https://doi.org/10.1016/j.ijcard.2021.11.079
    • Linkens, A. M. A., Houben, A. J. H. M., Kroon, A. A., Schram, M. T., Berendschot, T. T. J. M., Webers, C. A. B., van Greevenbroek, M., Henry, R. M. A., de Galan, B., Stehouwer, C. D. A., Eussen, S. J. M. P., & Schalkwijk, C. G. (2022). Habitual intake of dietary advanced glycation end products is not associated with generalized microvascular function-the Maastricht Study. American Journal of Clinical Nutrition, 115(2), 444-455. https://doi.org/10.1093/ajcn/nqab302
    • Weerts, J., Mourmans, S. G. J., Barandiaran Aizpurua, A., Schroen, B. L. M., Knackstedt, C., Eringa, E., Houben, A. J. H. M., & van Empel, V. P. M. (2022). The Role of Systemic Microvascular Dysfunction in Heart Failure with Preserved Ejection Fraction. Biomolecules, 12(2), Article 278. https://doi.org/10.3390/biom12020278
    • van Dinther, M., Schram, M. T., Jansen, J. F. A., Backes, W. H., Houben, A. J. H. M., Berendschot, T. T. J. M., Schalkwijk, C. G., Stehouwer, C. D. A., van Oostenbrugge, R. J., & Staals, J. (2022). Extracerebral microvascular dysfunction is related to brain MRI markers of cerebral small vessel disease: The Maastricht Study. Geroscience, 44(1), 147-157. https://doi.org/10.1007/s11357-021-00493-0
    • Beran, M., Muzambi, R., Geraets, A., Albertorio-Diaz, J. R., Adriaanse, M. C., Iversen, M. M., Kokoszka, A., Nefs, G., Nouwen, A., Pouwer, F., Huber, J. W., Schmitt, A., Schram, M. T., & European Depression in Diabetes (EDID) Research Consortium (2022). The bidirectional longitudinal association between depressive symptoms and HbA(1c): A systematic review and meta-analysis. Diabetic Medicine, 39(2), Article e14671. https://doi.org/10.1111/dme.14671
    • Jonkman, T. H., Dekkers, K. F., Slieker, R. C., Grant, C. D., Ikram, M. A., van Greevenbroek, M. M. J., Franke, L., Veldink, J. H., Boomsma, D. I., Slagboom, P. E., B. I. O. S. Consortium, & Heijmans, B. T. (2022). Functional genomics analysis identifies T and NK cell activation as a driver of epigenetic clock progression. Genome Biology, 23(1), Article 24. https://doi.org/10.1186/s13059-021-02585-8
    • Geraets, A. F. J., Köhler, S., & Schram, M. T. (2022). Vascular and metabolic risk factors of late-life depression. Vessel Plus, 6, Article 4750. https://doi.org/10.20517/2574-1209.2021.102
    • Maasen, K., Eussen, S. J. P. M., Scheijen, J. L. J. M., van der Kallen, C. J. H., Dagnelie, P. C., Opperhuizen, A., Stehouwer, C. D. A., van Greevenbroek, M. M. J., & Schalkwijk, C. G. (2022). Higher habitual intake of dietary dicarbonyls is associated with higher corresponding plasma dicarbonyl concentrations and skin autofluorescence: the Maastricht Study. American Journal of Clinical Nutrition, 115(1), 34-44. https://doi.org/10.1093/ajcn/nqab329
    • Obeid, R., Eussen, S. J. P. M., Mommers, M., Smits, L., & Thijs, C. (2022). Imbalanced Folate and Vitamin B12 in the Third Trimester of Pregnancy and its Association with Birthweight and Child Growth up to 2 Years. Molecular Nutrition & Food Research, 66(2), Article 2100662. https://doi.org/10.1002/mnfr.202100662
    • Hoogeveen, R. M., Hanssen, N. M. J., Brouwer, J. R., Mosterd, A., Tack, C. J., Kroon, A. A., De Borst, G. J., Ten Berg, J., Van Trier, T., Van Lennep, J. R., Liem, A., Serne, E., Visseren, F. L. J., Cornel, J. H., Peters, R. J. G., Jukema, J. W., Stroes, E. S. G., & PANORAMA working group (2022). The challenge of choosing in cardiovascular risk management. Netherlands Heart Journal, 30(1), 47-57. https://doi.org/10.1007/s12471-021-01599-y
    • van Geffen, M., van der Waaij, K. M., & Stassen, P. M. (2022). Number, nature & impact of incoming telephone calls on residents and their work during evening shifts. Acute Medicine, 21(1), 5-11. https://doi.org/10.52964/amja.0886
  • 2021
    • Malik, A. E. F., Delhaas, T., Spronck, B., Henry, R. M. A., Joseph, J., Stehouwer, C. D. A., Mess, W. H., & Reesink, K. D. (2021). Single M-Line Is as Reliable as Multiple M-Line Ultrasound for Carotid Artery Screening. Frontiers in physiology, 12, Article 787083. https://doi.org/10.3389/fphys.2021.787083
    • Mao, Z., Aglago, E. K., Zhao, Z., Schalkwijk, C., Jiao, L., Freisling, H., Weiderpass, E., Hughes, D. J., Eriksen, A. K., Tjønneland, A., Severi, G., Rothwell, J., Boutron-Ruault, M.-C., Katzke, V., Kaaks, R., Schulze, M. B., Birukov, A., Krogh, V., Panico, S., ... Fedirko, V. (2021). Dietary Intake of Advanced Glycation End Products (AGEs) and Mortality among Individuals with Colorectal Cancer. Nutrients, 13(12), Article 4435. https://doi.org/10.3390/nu13124435
    • Kalafati, M., Kutmon, M., Evelo, C. T., van der Kallen, C. J. H., Schalkwijk, C. G., Stehouwer, C. D. A., Blaak, E. E., van Greevenbroek, M. M. J., Adriaens, M., & BIOS Consortium (2021). An interferon-related signature characterizes the whole blood transcriptome profile of insulin-resistant individuals-the CODAM study. Genes and nutrition, 16(1), Article 22. https://doi.org/10.1186/s12263-021-00702-7
    • Latten, G. H. P., Polak, J., Merry, A. H. H., Muris, J. W. M., Ter Maaten, J. C., Olgers, T. J., Cals, J. W. L., & Stassen, P. M. (2021). Frequency of alterations in qSOFA, SIRS, MEWS and NEWS scores during the emergency department stay in infectious patients: a prospective study. International Journal of Emergency Medicine, 14(1), Article 69. https://doi.org/10.1186/s12245-021-00388-z
    • Mills, M. C., Tropf, F. C., Brazel, D. M., van Zuydam, N., Vaez, A., Agbessi, M., Ahsan, H., Alves, I., Andiappan, A. K., Arindrarto, W., Awadalla, P., Battle, A., Beutner, F., Jan Bonder, M., Boomsma, D. I., Christiansen, M. W., Claringbould, A., Deelen, P., Esko, T., ... Human Reproductive Behaviour Consortium (2021). Identification of 371 genetic variants for age at first sex and birth linked to externalising behaviour. Nature human behaviour, 5(12), 1717-1730. https://doi.org/10.1038/s41562-021-01135-3
    • Barutta, F., Corbetta, B., Bellini, S., Guarrera, S., Matullo, G., Scandella, M., Schalkwijk, C., Stehouwer, C. D., Chaturvedi, N., Soedamah-Muthu, S. S., Durazzo, M., & Gruden, G. (2021). MicroRNA 146a is associated with diabetic complications in type 1 diabetic patients from the EURODIAB PCS. Journal of Translational Medicine, 19(1), Article 475. https://doi.org/10.1186/s12967-021-03142-4
    • Gijs, M., Ramakers, I. H. G. B., Visser, P. J., Verhey, F. R. J., van de Waarenburg, M. P. H., Schalkwijk, C. G., Nuijts, R. M. M. A., & Webers, C. A. B. (2021). Association of tear fluid amyloid and tau levels with disease severity and neurodegeneration. Scientific Reports, 11(1), Article 22675. https://doi.org/10.1038/s41598-021-01993-x
    • van der Heide, F. C. T., Steens, I. L. M., Geraets, A. F. J., Foreman, Y. D., Henry, R. M. A., Kroon, A. A., van der Kallen, C. J. H., van Sloten, T. T., Dagnelie, P. C., van Dongen, M. C. J. M., Eussen, S. J. P. M., Berendschot, T. T. J. M., Schouten, J. S. A. G., Webers, C. A. B., van Greevenbroek, M. M. J., Wesselius, A., Koster, A., Schaper, N. C., Schram, M. T., ... Stehouwer, C. D. A. (2021). Association of Retinal Nerve Fiber Layer Thickness, an Index of Neurodegeneration, With Depressive Symptoms Over Time. Jama network open, 4(11), e2134753. Article 2134753. https://doi.org/10.1001/jamanetworkopen.2021.34753
    • Tinnevelt, G. H., Wouters, K., Postma, G. J., Folcarelli, R., & Jansen, J. J. (2021). High-throughput single cell data analysis - A tutorial. Analytica Chimica Acta, 1185, Article 338872. https://doi.org/10.1016/j.aca.2021.338872
    • Bogie, J. F. J., Vanmierlo, T., Vanmol, J., Timmermans, S., Mailleux, J., Nelissen, K., Wijnands, E., Wouters, K., Stinissen, P., Gustafsson, J. A., Steffensen, K. R., Mulder, M., Zelcer, N., & Hendriks, J. J. A. (2021). Liver X receptor beta deficiency attenuates autoimmune-associated neuroinflammation in a T cell-dependent manner. Journal of Autoimmunity, 124, Article 102723. https://doi.org/10.1016/j.jaut.2021.102723
    • Korn, A., Baylan, U., Simsek, S., Schalkwijk, C. G., Niessen, H. W. M., & Krijnen, P. A. J. (2021). Myocardial infarction coincides with increased NOX2 and Nε-(carboxymethyl) lysine expression in the cerebral microvasculature. Open Heart, 8(2), Article e001842. https://doi.org/10.1136/openhrt-2021-001842
    • Strikwerda, M., Beulens, J. W., Remmelzwaal, S., Schoonmade, L. J., van Straten, A., Schram, M. T., Elders, P. J., & Rutters, F. (2021). The Association of Burnout and Vital Exhaustion With Type 2 Diabetes: A Systematic Review and Meta-Analysis. Psychosomatic Medicine, 83(9), 1013-1030. https://doi.org/10.1097/PSY.0000000000000995
    • van Gennip, A. C. E., Stehouwer, C. D. A., van Boxtel, M. P. J., Verhey, F. R. J., Koster, A., Kroon, A. A., Köhler, S., van Greevenbroek, M. M. J., Wesselius, A., Eussen, S. J. P. M., Backes, W. H., Jansen, J. F., Schram, M. T., Henry, R. M. A., Singh-Manoux, A., & van Sloten, T. T. (2021). Association of Type 2 Diabetes, According to the Number of Risk Factors Within Target Range, With Structural Brain Abnormalities, Cognitive Performance, and Risk of Dementia. Diabetes Care, 44(11), 2493-2502. https://doi.org/10.2337/dc21-0149
    • Bakker, L., Ramakers, I. H. G. B., van Boxtel, M. P. J., Schram, M. T., Stehouwer, C. D. A., van der Kallen, C. J. H., Dagnelie, P. C., van Greevenbroek, M. M. J., Wesselius, A., Midttun, Ø., Ueland, P. M., Verhey, F. R. J., Eussen, S. J. P. M., & Köhler, S. (2021). Associations between plasma kynurenines and cognitive function in individuals with normal glucose metabolism, prediabetes and type 2 diabetes: the Maastricht Study. Diabetologia, 64(11), 2445-2457. https://doi.org/10.1007/s00125-021-05521-4
    • Wu, W., Bours, M., Koole, A., Kenkhuis, M. F., Eussen, S., Breukink, S., van Schooten, F., Weijenberg, M., & Hageman, G. (2021). Cross-Sectional Associations between Dietary Daily Nicotinamide Intake and Patient-Reported Outcomes in Colorectal Cancer Survivors, 2 to 10 Years Post-Diagnosis. Nutrients, 13(11), Article 3707. https://doi.org/10.3390/nu13113707
    • van der Bruggen, M. M., Spronck, B., Delhaas, T., Reesink, K. D., & Schalkwijk, C. G. (2021). The Putative Role of Methylglyoxal in Arterial Stiffening: A Review. Heart Lung and Circulation, 30(11), 1681-1693. https://doi.org/10.1016/j.hlc.2021.06.527
    • van Dalem, J., Driessen, J. H. M., Burden, A. M., Stehouwer, C. D. A., Klungel, O. H., de Vries, F., & Brouwers, M. C. G. J. (2021). Thiazolidinediones and Glucagon-Like Peptide-1 Receptor Agonists and the Risk of Nonalcoholic Fatty Liver Disease: A Cohort Study. Hepatology, 74(5), 2467-2477. https://doi.org/10.1002/hep.32012
    • Kremers, S. H. M., Remmelzwaal, S., Schalkwijk, C. G., Elders, P. J. M., Stehouwer, C. D. A., van Ballegooijen, A. J., & Beulens, J. W. J. (2021). The role of serum and dietary advanced glycation endproducts in relation to cardiac function and structure: The Hoorn Study. Nutrition Metabolism and Cardiovascular Diseases, 31(11), 3167-3175. https://doi.org/10.1016/j.numecd.2021.07.020
    • Pinxt, C. M. H., Bogie, R. M. M., Hanssen, N. M. J., & Spaetgens, B. (2021). Antibiotic overuse in older patients: an important clinical reminder of pseudomembranous colitis. QJM: An International Journal of Medicine, 114(10), 755-756. https://doi.org/10.1093/qjmed/hcab198
    • Gianfredi, V., Beran, M., Koster, A., Eussen, S. J. P. M., Odone, A., Signorelli, C., Schaper, N. C., Köhler, S., Bosma, H., Dagnelie, P. C., Stehouwer, C. D. A., Wesselius, A., Amerio, A., Brinkhues, S., Dukers-Muijrers, N., & Schram, M. T. (2021). Association between social network characteristics and prevalent and incident depression: The Maastricht Study. Journal of Affective Disorders, 293, 338-346. https://doi.org/10.1016/j.jad.2021.06.046
    • Gijs, M., Veugen, J. M. J., Wolffs, P. F. G., Savelkoul, P. H. M., Tas, J., van Bussel, B. C. T., de Kruif, M. D., Henry, R. M. A., Webers, C. A. B., Dickman, M. M., & Nuijts, R. M. M. A. (2021). In-Depth Investigation of Conjunctival Swabs and Tear Fluid of Symptomatic COVID-19 Patients, an Observational Cohort Study. Translational Vision Science & Technology, 10(12), Article 32. https://doi.org/10.1167/tvst.10.12.32
    • Janssen, E. P. C. J., Köhler, S., Geraets, A. F. J., Stehouwer, C. D. A., Schaper, N. C., Sep, S. J. S., Henry, R. M. A., van der Kallen, C. J. H., Schalkwijk, C. G., Koster, A., Verhey, F. R., & Schram, M. T. (2021). Low-grade inflammation and endothelial dysfunction predict four-year risk and course of depressive symptoms: The Maastricht study. Brain Behavior and Immunity, 97, 61-67. https://doi.org/10.1016/j.bbi.2021.06.013
    • Molto-Puigmarti, C., Obeid, R., Mommers, M., Eussen, S. J. P. M., & Thijs, C. (2021). Maternal plasma choline and betaine in late pregnancy and child growth up to age 8 years in the KOALA Birth Cohort Study. American Journal of Clinical Nutrition, 114(4), 1438-1446. https://doi.org/10.1093/ajcn/nqab177
    • Daemen, S., van Polanen, N., Bilet, L., Phielix, E., Moonen-Kornips, E., Schrauwen-Hinderling, V. B., Schrauwen, P., & Hesselink, M. K. C. (2021). Postexercise changes in myocellular lipid droplet characteristics of young lean individuals are affected by circulatory nonesterified fatty acids. American Journal of Physiology : Endocrinology and Metabolism, 321(4), E453-E463. https://doi.org/10.1152/ajpendo.00654.2020
    • Heger, I. S., Deckers, K., Schram, M. T., Stehouwer, C. DA., Dagnelie, P. C., van der Kallen, C. J., Koster, A., Eussen, S. J., Jansen, J. F., Verhey, F. R., van Boxtel, M. P., & Köhler, S. (2021). Associations of the Lifestyle for Brain Health Index With Structural Brain Changes and Cognition: Results From the Maastricht Study. Neurology, 97(13), E1300-E1312. https://doi.org/10.1212/WNL.0000000000012572
    • Aglago, E. K., Mayen, A. L., Knaze, V., Freisling, H., Fedirko, V., Hughes, D. J., Jiao, L., Eriksen, A. K., Tjonneland, A., Boutron-Ruault, M. C., Rothwell, J. A., Severi, G., Kaaks, R., Katzke, V., Schulze, M. B., Birukov, A., Palli, D., Sieri, S., de Magistris, M. S., ... Jenab, M. (2021). Dietary Advanced Glycation End-Products and Colorectal Cancer Risk in the European Prospective Investigation into Cancer and Nutrition (EPIC) Study. Nutrients, 13(9), Article 3132. https://doi.org/10.3390/nu13093132
    • Geraets, A. F. J., Köhler, S., Jansen, J. F. A., Eussen, S. J. P. M., Stehouwer, C. D. A., Schaper, N. C., Wesselius, A., Verhey, F. R. J., & Schram, M. T. (2021). The association of markers of cerebral small vessel disease and brain atrophy with incidence and course of depressive symptoms-the maastricht study. Journal of Affective Disorders, 292, 439-447. https://doi.org/10.1016/j.jad.2021.05.096
    • van Dongen, K. C. W., Linkens, A. M. A., Wetzels, S. M. W., Wouters, K., Vanmierlo, T., van de Waarenburg, M. P. H., Scheijen, J. L. J. M., de Vos, W. M., Belzer, C., & Schalkwijk, C. G. (2021). Dietary advanced glycation endproducts (AGEs) increase their concentration in plasma and tissues, result in inflammation and modulate gut microbial composition in mice; evidence for reversibility. Food Research International, 147, Article 110547. https://doi.org/10.1016/j.foodres.2021.110547