• 2011
    • Bis, J. C., Kavousi, M., Franceschini, N., Isaacs, A., Abecasis, G. R., Schminke, U., Post, W. S., Smith, A. V., Cupples, L. A., Markus, H. S., Schmidt, R., Huffman, J. E., Lehtimäki, T., Baumert, J., Münzel, T., Heckbert, S. R., Dehghan, A., North, K., Oostra, B., ... CARDIoGRAM Consortium (2011). Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common variants associated with carotid intima media thickness and plaque. Nature Genetics, 43(10), 940-7. https://doi.org/10.1038/ng.920
    • Panova-Noeva, M., Marchetti, M., Buoro, S., Russo, L., Leuzzi, A., Finazzi, G., Rambaldi, A., Ottomano, C., ten Cate, H., & Falanga, A. (2011). JAK2V617F mutation and hydroxyurea treatment as determinants of immature platelet parameters in essential thrombocythemia and polycythemia vera patients. Blood, 118(9), 2599-2601. https://doi.org/10.1182/blood-2011-02-339655
    • Schuur, M., Ikram, M. A., van Swieten, J. C., Isaacs, A., Vergeer-Drop, J. M., Hofman, A., Oostra, B. A., Breteler, M. M. B., & van Duijn, C. M. (2011). Cathepsin D gene and the risk of Alzheimer's disease: a population-based study and meta-analysis. Neurobiology of Aging, 32(9), 1607-14. https://doi.org/10.1016/j.neurobiolaging.2009.10.011
    • Panizzi, P., Nahrendorf, M., Figueiredo, J.-L., Panizzi, J., Marinelli, B., Iwamoto, Y., Keliher, E., Maddur, A. A., Waterman, P., Kroh, H. K., Leuschner, F., Aikawa, E., Swirski, F. K., Pittet, M. J., Hackeng, T. M., Fuentes-Prior, P., Schneewind, O., Bock, P. E., & Weissleder, R. (2011). In vivo detection of Staphylococcus aureus endocarditis by targeting pathogen-specific prothrombin activation. Nature Medicine, 17(9), 1142-U153. https://doi.org/10.1038/nm.2423
    • Vasina, E. M., Cauwenberghs, S., Feijge, M. A. H., Heemskerk, J. W. M., Weber, C., & Koenen, R. R. (2011). Microparticles from apoptotic platelets promote resident macrophage differentiation. Cell Death & Disease, 2(9), 10. Article e211. https://doi.org/10.1038/cddis.2011.94
    • Nergiz-Unal, R., Lamers, M. M. E., Van Kruchten, R., Luiken, J. J., Cosemans, J. M. E. M., Glatz, J. F. C., Kuijpers, M. J. E., & Heemskerk, J. W. M. (2011). Signaling role of CD36 in platelet activation and thrombus formation on immobilized thrombospondin or oxidized low-density lipoprotein. Journal of Thrombosis and Haemostasis, 9(9), 1835-1846. https://doi.org/10.1111/j.1538-7836.2011.04416.x
    • Kornfeld, J.-W., Isaacs, A., Vitart, V., Pospisilik, J. A., Meitinger, T., Gyllensten, U., Wilson, J. F., Rudan, I., Campbell, H., Penninger, J. M., Sexl, V., Moriggl, R., van Duijn, C., Pramstaller, P. P., & Hicks, A. A. (2011). Variants in STAT5B associate with serum TC and LDL-C levels. Journal of Clinical Endocrinology & Metabolism, 96(9), E1496-501. https://doi.org/10.1210/jc.2011-0322
    • Grottke, O., Braunschweig, T., Spronk, H. M. H., Esch, S., Rieg, A. D., van Oerle, R., ten Cate, H., Fitzner, C., Tolba, R., & Rossaint, R. (2011). Increasing concentrations of prothrombin complex concentrate induce disseminated intravascular coagulation in a pig model of coagulopathy with blunt liver injury. Blood, 118(7), 1943-1951. https://doi.org/10.1182/blood-2011-03-343046
    • Schiepers, O. J. G., van Boxtel, M. P. J., de Groot, R. H. M., Jolles, J., Bekers, O., Kok, F. J., Verhoef, P., & Durga, J. (2011). Genetic variation in folate metabolism is not associated with cognitive functioning or mood in healthy adults. Progress in Neuro-Psychopharmacology & Biological Psychiatry, 35(7), 1682-1688. https://doi.org/10.1016/j.pnpbp.2011.06.008
    • Ninivaggi, M., Dargaud, Y., Van Oerle, R., De Laat, B., Hemker, H. C., & Lindhout, T. (2011). Thrombin generation assay using factor IXa as a trigger to quantify accurately factor VIII levels in haemophilia A. Journal of Thrombosis and Haemostasis, 9(8), 1549-1555. https://doi.org/10.1111/j.1538-7836.2011.04358.x
    • Bouman, H. J., Harmsze, A. M., van Werkum, J. W., Breet, N. J., Bergmeijer, T. O., ten Cate, H., Hackeng, C. M., Deneer, V. H. M., & Ten Berg, J. M. (2011). Variability in on-treatment platelet reactivity explained by CYP2C19*2 genotype is modest in clopidogrel pretreated patients undergoing coronary stenting. Heart, 97(15), 1239-1244. https://doi.org/10.1136/hrt.2010.220509
    • Konopatskaya, O., Matthews, S. A., Harper, M. T., Gilio, K., Cosemans, J. M. E. M., Williams, C. M., Navarro, M. N., Carter, D. A., Heemskerk, J. W. M., Leitges, M., Cantrell, D., & Poole, A. W. (2011). Protein kinase C mediates platelet secretion and thrombus formation through protein kinase D2. Blood, 118(2), 416-424. https://doi.org/10.1182/blood-2010-10-312199
    • Kilinc, E., Van Oerle, R., Borissoff, J. I., Oschatz, C., Gerlofs Nijland, M. E., Janssen, N. A., Cassee, F. R., Sandstrom, T., Renne, T., Ten Cate, H., & Spronk, H. M. H. (2011). Factor XII activation is essential to sustain the procoagulant effects of particulate matter. Journal of Thrombosis and Haemostasis, 9(7), 1359-1367. https://doi.org/10.1111/j.1538-7836.2011.04280.x
    • Demirkan, A., Amin, N., Isaacs, A., Jarvelin, M.-R., Whitfield, J. B., Wichmann, H.-E., Kyvik, K. O. H. M., Rudan, I., Gieger, C., Hicks, A. A., Johansson, Å., Hottenga, J.-J., Smith, J. J., Wild, S. H., Pedersen, N. L., Willemsen, G., Mangino, M., Hayward, C., Uitterlinden, A. G., ... ENGAGE Consortium (2011). Genetic architecture of circulating lipid levels. European Journal of Human Genetics, 19(7), 813-9. https://doi.org/10.1038/ejhg.2011.21
    • Heemskerk, J. W. M., Harper, M. T., Cosemans, J. M. E. M., & Poole, A. W. (2011). Unravelling the different functions of protein kinase C isoforms in platelets. Febs Letters, 585(12), 1711-1716. https://doi.org/10.1016/j.febslet.2011.05.017
    • Douma, R. A., Mos, I. C. M., Erkens, P. M. G., Nizet, T. A. C., Durian, M. F., Hovens, M. M. C., van Houten, A., Hofstee, H. M. A., Klok, F. A., ten Cate, H., Ullmann, E. F., Buller, H. R., Kamphuisen, P. W., & Huisman, M. V. (2011). Performance of 4 Clinical Decision Rules in the Diagnostic Management of Acute Pulmonary Embolism A Prospective Cohort Study. Annals of Internal Medicine, 154(11), 14-718. https://doi.org/10.7326/0003-4819-154-11-201106070-00002
    • Maas, A. H. E. M., van der Schouw, Y. T., Regitz-Zagrosek, V., Swahn, E., Appelman, Y. E., Pasterkamp, G., ten Cate, H., Nilsson, P. M., Huisman, M. V., Stam, H. C. G., Eizema, K., & Stramba-Badiale, M. (2011). Red alert for women's heart: the urgent need for more research and knowledge on cardiovascular disease in women. European Heart Journal, 32(11), 1362-U89. https://doi.org/10.1093/eurheartj/ehr048
    • Borissoff, J. I., Spronk, H. M. H., & ten Cate, H. (2011). MECHANISMS OF DISEASE The Hemostatic System as a Modulator of Atherosclerosis. New England Journal of Medicine, 364(18), 1746-1760. https://doi.org/10.1056/NEJMra1011670
    • Bastings, M. M. C., Helms, B. A., van Baal, I., Hackeng, T. M., Merkx, M. A. G., & Meijer, E. W. (2011). From Phage Display to Dendrimer Display: Insights into Multivalent Binding. Journal of the American Chemical Society, 133(17), 6636-6641. https://doi.org/10.1021/ja110700x
    • Bouman, H. J., van Werkum, J. W., Breet, N. J., ten Cate, H., Hackeng, C. M., & Ten Berg, J. M. (2011). A case-control study on platelet reactivity in patients with coronary stent thrombosis. Journal of Thrombosis and Haemostasis, 9(5), 909-916. https://doi.org/10.1111/j.1538-7836.2011.04255.x
    • Castoldi, E., Duckers, C., Radu, C. M., Spiezia, L., Rossetto, V., Tagariello, G., Rosing, J., & Simioni, P. (2011). Homozygous F5 deep-intronic splicing mutation resulting in severe factor V deficiency and undetectable thrombin generation in platelet-rich plasma. Journal of Thrombosis and Haemostasis, 9(5), 959-968. https://doi.org/10.1111/j.1538-7836.2011.04237.x
    • Debats, I. B., Koeneman, M. M., Booi, D. I., Bekers, O., & van der Hulst, R. R. W. J. (2011). Intravenous arginine and human skin graft donor site healing: A randomized controlled trial.Burns, 37(3), 420-426. https://doi.org/10.1016/j.burns.2010.06.003
    • Wijnen, P. A. H. M., Voorter, C. E., Nelemans, P. J., Verschakelen, J. A., Bekers, O., & Drent, M. (2011). Butyrophilin-like 2 in pulmonary sarcoidosis: a factor for susceptibility and progression?Human Immunology, 72(4), 342-347. https://doi.org/10.1016/j.humimm.2011.01.011
    • Trappenburg, M. C., van Schilfgaarde, M., Bredewold, E. O., van Aalderen, M. C., Spronk, H. M. H., ten Cate, H., Leyte, A., & Terpstra, W. E. (2011). Elevated numbers and altered subsets of procoagulant microparticles in breast cancer patients using endocrine therapy. Thrombosis Research, 127(4), 363-369. https://doi.org/10.1016/j.thromres.2010.12.015
    • Panova-Noeva, M., Marchetti, M., Spronk, H. M., Russo, L., Diani, E., Finazzi, G., Salmoiraghi, S., Rambaldi, A., Barbui, T., Ten Cate, H., & Falanga, A. (2011). Platelet-induced thrombin generation by the calibrated automated thrombogram assay is increased in patients with essential thrombocythemia and polycythemia vera. American Journal of Hematology, 86(4), 337-342. https://doi.org/10.1002/ajh.21974
    • Kilinc, E., Schulz, H., Kuiper, G. J. A. J. M., Spronk, H. M. H., ten Cate, H., Upadhyay, S., Ganguly, K., Stoeger, T., Semmler-Bhenke, M., Takenaka, S., Kreyling, W. G., Pitz, M., Reitmeir, P., Peters, A., Eickelberg, O., & Wichmann, H. E. (2011). The procoagulant effects of fine particulate matter in vivo. Particle and Fibre Toxicology, 8, 3. https://doi.org/10.1186/1743-8977-8-12
    • Kramp, B. K., Sarabi, A., Koenen, R. R., & Weber, C. (2011). Heterophilic chemokine receptor interactions in chemokine signaling and biology. Experimental Cell Research, 317(5), 655-663. https://doi.org/10.1016/j.yexcr.2010.11.014
    • Lexis, C. P. H., van der Horst, I. C. C., Rahel, B. M., Lexis, M. A. S., Kampinga, M. A., Gu, Y. L., de Smet, B. J. G. L., & Zijlstra, F. (2011). Impact of Chronic Total Occlusions on Markers of Reperfusion, Infarct Size, and Long-Term Mortality: A Substudy from the TAPAS-Trial. Catheterization and Cardiovascular interventions, 77(4), 484-491. https://doi.org/10.1002/ccd.22664
    • Brugts, J. J., Isaacs, A., de Maat, M. P., Boersma, E., van Duijn, C. M., Akkerhuis, K. M., Uitterlinden, A. G., Witteman, J. C., Cambien, F., Ceconi, C., Remme, W., Bertrand, M., Ninomiya, T., Harrap, S., Chalmers, J., Macmahon, S., Fox, K., Ferrari, R., Simoons, M. L., & Danser, A. J. (2011). A pharmacogenetic analysis of determinants of hypertension and blood pressure response to angiotensin-converting enzyme inhibitor therapy in patients with vascular disease and healthy individuals. Journal of Hypertension, 29(3), 509-19. https://doi.org/10.1097/HJH.0b013e328341d117
    • Obermann-Borst, S. A., Isaacs, A., Younes, Z., van Schaik, R. H. N., van der Heiden, I. P., van Duyn, C. M., Steegers, E. A. P., & Steegers-Theunissen, R. P. M. (2011). General maternal medication use, folic acid, the MDR1 C3435T polymorphism, and the risk of a child with a congenital heart defect. American Journal of Obstetrics and Gynecology, 204(3), 236.e1-8. https://doi.org/10.1016/j.ajog.2010.10.911
    • Smid, M., Dielis, A. W. J. H., Winkens, M. H. M., Spronk, H. M. H., van Oerle, R., Hamulyak, K., Prins, M. H., Rosing, J., Waltenberger, J. L., & ten Cate, H. (2011). Thrombin generation in patients with a first acute myocardial infarction. Journal of Thrombosis and Haemostasis, 9(3), 450-456. https://doi.org/10.1111/j.1538-7836.2010.04162.x
    • de Jager, S. C. A., Bermudez, B., Bot, I., Koenen, R. R., Bot, M., Kavelaars, A., de Waard, V., Heijnen, C. J., Muriana, F. J. G., Weber, C., van Berkel, T. J. C., Kuiper, J., Lee, S.-J., Abia, R., & Biessen, E. A. L. (2011). Growth differentiation factor 15 deficiency protects against atherosclerosis by attenuating CCR2-mediated macrophage chemotaxis. Journal of Experimental Medicine, 208(2), 217-225. https://doi.org/10.1084/jem.20100370
    • Coolen, E. J., Arts, I. C., Bekers, O., Vervaet, C., Bast, A., & Dagnelie, P. C. (2011). Oral bioavailability of ATP after prolonged administration.British Journal of Nutrition, 105(3), 357-366. https://doi.org/10.1017/S0007114510003570
    • Castoldi, E., & Rosing, J. (2011). Thrombin generation tests. Thrombosis Research, 127(SUPPL. 3), S21-S25. https://doi.org/10.1016/S0049-3848(11)70007-X
    • van Schie, M. C., de Maat, M. P. M., Isaacs, A., van Duijn, C. M., Deckers, J. W., Dippel, D. W. J., & Leebeek, F. W. G. (2011). Variation in the von Willebrand factor gene is associated with von Willebrand factor levels and with the risk for cardiovascular disease. Blood, 117(4), 1393-9. https://doi.org/10.1182/blood-2010-03-273961
    • Ungethum, L., Kenis, H., Nicolaes, G. A., Autin, L., Stoilova-McPhie, S., & Reutelingsperger, C. P. M. (2011). Engineered Annexin A5 Variants Have Impaired Cell Entry for Molecular Imaging of Apoptosis Using Pretargeting Strategies. Journal of Biological Chemistry, 286(3), 1903-1910. https://doi.org/10.1074/jbc.M110.163527
    • Cosemans, J. M. E. M., Schols, S. E. M., Stefanini, L., de Witt, S., Feijge, M. A. H., Hamulyak, K., Deckmyn, H., Bergmeier, W., & Heemskerk, J. W. M. (2011). Key role of glycoprotein Ib/V/IX and von Willebrand factor in platelet activation-dependent fibrin formation at low shear flow. Blood, 117(2), 651-660. https://doi.org/10.1182/blood-2010-01-262683
    • Wijnen, P. A. H. M., Bekers, O., & Drent, M. (2011). Development of Cocaine-Induced Interstitial Lung Damage in Two CYP2C and VKORC1 Variant Allele Carriers. Molecular Diagnosis & Therapy, 15(3), 177-180. https://doi.org/10.1007/BF03256408
    • Sep, S., Rijvers, C., Smits, L., van Bilsen, M., Bekers, O., & Peeters, L. (2011). Early-pregnancy changes in maternal lipid profile in women with recurrent preeclampsia and previously preeclamptic women with normal next pregnancy. Reproductive Sciences, 18(10), 998-1004. https://doi.org/10.1177/1933719111401665
    • van Bussel, B. C. T., Schouten, F., Henry, R. M., Schalkwijk, C. G., de Boer, M. R., Ferreira, I., Smulders, Y. M., Twisk, J. W., & Stehouwer, C. D. A. (2011). Endothelial Dysfunction and Low-Grade Inflammation Are Associated With Greater Arterial Stiffness Over a 6-Year Period. Hypertension, 58(4), 588-595. https://doi.org/10.1161/HYPERTENSIONAHA.111.174557
    • van Bussel, B. C. T., Henry, R. M., Schalkwijk, C. G., Ferreira, I., Feskens, E. J., Streppel, M. T., Smulders, Y. M., Twisk, J. W., & Stehouwer, C. D. A. (2011). Fish consumption in healthy adults is associated with decreased circulating biomarkers of endothelial dysfunction and inflammation during a 6-year follow-up. Journal of Nutrition, 141(9), 1719-1725. https://doi.org/10.3945/jn.111.139733
    • Sarabi, A., Kramp, B. K., Drechsler, M., Hackeng, T. M., Soehnlein, O., Weber, C., Koenen, R. R., & von Hundelshausen, P. (2011). CXCL4L1 inhibits angiogenesis and induces undirected endothelial cell migration without affecting endothelial cell proliferation and monocyte recruitment. Journal of Thrombosis and Haemostasis, 9(1), 209-219. https://doi.org/10.1111/j.1538-7836.2010.04119.x
    • Korporaal, S. J. A., Meurs, I., Hauer, A. D., Hildebrand, R. B., Hoekstra, M., Ten Cate, H., Pratico, D., Akkerman, J.-W. N., van Berkel, T. J. C., Kuiper, J., & Van Eck, M. (2011). Deletion of the High-Density Lipoprotein Receptor Scavenger Receptor BI in Mice Modulates Thrombosis Susceptibility and Indirectly Affects Platelet Function by Elevation of Plasma Free Cholesterol. Arteriosclerosis Thrombosis and Vascular Biology, 31(1), 34–42. https://doi.org/10.1161/ATVBAHA.110.210252
    • Schuur, M., van Swieten, J. C., Schol-Gelok, S., Ikram, M. A., Vernooij, M. W., Liu, F., Isaacs, A., de Boer, R., de Koning, I., Niessen, W. J., Vrooman, H., Oostra, B. A., van der Lugt, A., Breteler, M. M. B., & van Duijn, C. M. (2011). Genetic risk factors for cerebral small-vessel disease in hypertensive patients from a genetically isolated population. Journal of Neurology Neurosurgery and Psychiatry, 82(1), 41-4. https://doi.org/10.1136/jnnp.2009.176362
    • Meex, S. J. R., Andreo, U., Sparks, J. D., & Fisher, E. A. (2011). Huh-7 or HepG2 cells: which is the better model for studying human apolipoprotein-B100 assembly and secretion?Journal of Lipid Research, 52(1), 152-158. https://doi.org/10.1194/jlr.D008888
    • van Doormaal, F. F., Terpstra, W. A., van der Griend, R., Prins, M. H., Nijziel, M. R., van de Ree, M. A., Buller, H. R., Dutilh, J. C., Ten Cate-Hoek, A., van den Heiligenberg, S. M., van der Meer, R., & Otten, J. M. (2011). Is extensive screening for cancer in idiopathic venous thromboembolism warranted?Journal of Thrombosis and Haemostasis, 9(1), 79-84. https://doi.org/10.1111/j.1538-7836.2010.04101.x
    • Janssen, K. J. M., van der Velde, E. F., Ten Cate-Hoek, A. J., Prins, M. H., van Weert, H. C. P. M., Stoffers, H. E. J. H. J., Buller, H. R., Oudega, R., Hoes, A. W., Toll, D. B., & Moons, K. G. M. (2011). Optimisation of the diagnostic strategy for suspected deep-vein thrombosis in primary care. Thrombosis and Haemostasis, 105(1), 154-160. https://doi.org/10.1160/TH10-04-0242
    • Gerards, M., van den Bosch, B. J. C., Danhauser, K., Serre, V., van Weeghel, M., Wanders, R. J. A., Nicolaes, G. A. F., Sluiter, W., Schoonderwoerd, K., Scholte, H. R., Prokisch, H., Rötig, A., de Coo, I. F. M., & Smeets, H. J. M. (2011). Riboflavin-responsive oxidative phosphorylation complex I deficiency caused by defective ACAD9: new function for an old gene. Brain, 134(Pt 1), 210-219. https://doi.org/10.1093/brain/awq273
    • van der Velde, E. F., Toll, D. B., ten Cate-Hoek, A. J., Oudega, R., Stoffers, H. E. J. H. J., Bossuyt, P. M., Buller, H. R., Prins, M. H., Hoes, A. W., Moons, K. G. M., & van Weert, H. C. P. M. (2011). Comparing the Diagnostic Performance of 2 Clinical Decision Rules to Rule Out Deep Vein Thrombosis in Primary Care Patients. Annals of Family Medicine, 9(1), 31-36. https://doi.org/10.1370/afm.1198
    • Shoshan, M. S., Shalev, D. E., Adriaens, W., Merkx, M. A. G., Hackeng, T. M., & Tshuva, E. Y. (2011). NMR characterization of a Cu(I)-bound peptide model of copper metallochaperones: Insights on the role of methionine. Chemical Communications, 47(22), 6407-6409. https://doi.org/10.1039/c1cc11600b