• 2013
    • Prinzen, L., Staal, H. M., Rouwette, S. J. M., Beckers, E. A. M., ten Broeke, R. H. M., van Rhijn, L. W., & Henskens, Y. M. C. (2013). Triple Red Blood Cell Alloantibody Formation After Bone-Allograft Transplantation. American Journal of Transplantation, 13(1), 229-231. https://doi.org/10.1111/j.1600-6143.2012.04300.x
    • Vasina, E. M., Cauwenberghs, S., Staudt, M., Feijge, M. A., Weber, C., Koenen, R. R., & Heemskerk, J. W. (2013). Aging- and activation-induced platelet microparticles suppress apoptosis in monocytic cells and differentially signal to proinflammatory mediator release. American Journal of Blood Research, 3(2), 107-23. https://pubmed.ncbi.nlm.nih.gov/23675563/
    • Tijink, M., Janssen, J., Timmer, M., Austen, J., Aldenhoff, Y., Kooman, J., Koole, L., Damoiseaux, J., van Oerle, R., Henskens, Y., & Stamatialis, D. (2013). Development of novel membranes for blood purification therapies based on copolymers of N-vinylpyrrolidone and n-butylmethacrylate. Journal of Materials Chemistry. B, Materials for Biology and Medicine, 1(44), 6066-6077. https://doi.org/10.1039/c3tb20964d
    • Lance, M. D., Henskens, Y., Nelemans, P., Theunissen, M. H. S., Van Oerle, R., Spronk, H. M., & Marcus, M. A. E. (2013). Do blood collection methods influence whole-blood platelet function analysis?Platelets, 24(4), 275-281. https://doi.org/10.3109/09537104.2012.689038
    • van der Loos, M. J. H. M., Rietveld, C. A., Eklund, N., Koellinger, P. D., Rivadeneira, F., Abecasis, G. R., Ankra-Badu, G. A., Baumeister, S. E., Benjamin, D. J., Biffar, R., Blankenberg, S., Boomsma, D. I., Cesarini, D., Cucca, F., de Geus, E. J. C., Dedoussis, G., Deloukas, P., Dimitriou, M., Eiriksdottir, G., ... Thurik, A. R. (2013). The molecular genetic architecture of self-employment. PLOS ONE, 8(4), e60542. https://doi.org/10.1371/journal.pone.0060542
    • Fall, T., Hägg, S., Mägi, R., Ploner, A., Fischer, K., Horikoshi, M., Sarin, A.-P., Thorleifsson, G., Ladenvall, C., Kals, M., Kuningas, M., Draisma, H. H. M., Ried, J. S., van Zuydam, N. R., Huikari, V., Mangino, M., Sonestedt, E., Benyamin, B., Nelson, C. P., ... European Network for Genetic and Genomic Epidemiology (ENGAGE) consortium (2013). The role of adiposity in cardiometabolic traits: a Mendelian randomization analysis. PLOS Medicine , 10(6), e1001474. https://doi.org/10.1371/journal.pmed.1001474
  • 2012
    • Chasman, D. I., Fuchsberger, C., Pattaro, C., Teumer, A., Böger, C. A., Endlich, K., Olden, M., Chen, M.-H., Tin, A., Taliun, D., Li, M., Gao, X., Gorski, M., Yang, Q., Hundertmark, C., Foster, M. C., O'Seaghdha, C. M., Glazer, N., Isaacs, A., ... CARDIoGRAM Consortium (2012). Integration of genome-wide association studies with biological knowledge identifies six novel genes related to kidney function. Human Molecular Genetics, 21(24), 5329-43. https://doi.org/10.1093/hmg/dds369
    • Borissoff, J. I., Joosen, I. A., Versteylen, M. O., Spronk, H. M., ten Cate, H., & Hofstra, L. (2012). Accelerated In Vivo Thrombin Formation Independently Predicts the Presence and Severity of CT Angiographic Coronary Atherosclerosis. JACC-Cardiovascular Imaging, 5(12), 1201-1210. https://doi.org/10.1016/j.jcmg.2012.01.023
    • Dargaud, Y., Wolberg, A. S., Luddington, R., Regnault, V., Spronk, H., Baglin, T., Lecompte, T., Ten Cate, H., & Negrier, C. (2012). Evaluation of a standardized protocol for thrombin generation measurement using the calibrated automated thrombogram: An international multicentre study. Thrombosis Research, 130(6), 929-934. https://doi.org/10.1016/j.thromres.2012.07.017
    • Ibrahim-Verbaas, C. A., Zorkoltseva, I. V., Amin, N., Schuur, M., Coppus, A. M. W., Isaacs, A., Aulchenko, Y. S., Breteler, M. M. B., Ikram, M. A., Axenovich, T. I., Verbeek, M. M., van Swieten, J. C., Oostra, B. A., & van Duijn, C. M. (2012). Linkage analysis for plasma amyloid beta levels in persons with hypertension implicates Aβ-40 levels to presenilin 2. Human Genetics, 131(12), 1869-76. https://doi.org/10.1007/s00439-012-1210-2
    • Projahn, D., & Koenen, R. R. (2012). Platelets: key players in vascular inflammation. Journal of Leukocyte Biology, 92(6), 1167-1175. https://doi.org/10.1189/jlb.0312151
    • Loeffen, R., Kleinegris, M. .-C. F., Loubele, S. T. B. G., Pluijmen, P. H. M., Fens, D., van Oerle, R., ten Cate, H., & Spronk, H. M. H. (2012). Preanalytic variables of thrombin generation: towards a standard procedure and validation of the method. Journal of Thrombosis and Haemostasis, 10(12), 2544-2554. https://doi.org/10.1111/jth.12012
    • Van de Vijver, P., Schmitt, M., Suylen, D., Scheer, L., Thomassen, M. C. L. G. D., Schurgers, L. J., Griffin, J. H., Koenen, R. R., & Hackeng, T. M. (2012). Incorporation of Disulfide Containing Protein Modules into Multivalent Antigenic Conjugates: Generation of Antibodies against the Thrombin-Sensitive Region of Murine Protein S. Journal of the American Chemical Society, 134(47), 19318-19321. https://doi.org/10.1021/ja306993t
    • Geenen, I. L., Post, M. J., Molin, D. G. M., Schurink, G. W. H., Maessen, J. G., van Oerle, R., ten Cate, H., & Spronk, H. M. H. (2012). Coagulation on endothelial cells: the underexposed part of Virchow's Triad. Thrombosis and Haemostasis, 108(5), 863-871. https://doi.org/10.1160/TH12-04-0269
    • Amin, N., Byrne, E., Johnson, J., Chenevix-Trench, G., Walter, S., Nolte, I. M., Vink, J. M., Rawal, R., Mangino, M., Teumer, A., Keers, J. C., Verwoert, G., Baumeister, S., Biffar, R., Petersmann, A., Dahmen, N., Doering, A., Isaacs, A., Broer, L., ... van Duijn, C. M. (2012). Genome-wide association analysis of coffee drinking suggests association with CYP1A1/CYP1A2 and NRCAM. Molecular Psychiatry, 17(11), 1116-29. https://doi.org/10.1038/mp.2011.101
    • Nazari-Jahantigh, M., Wei, Y., Noels, H., Akhtar, S., Zhou, Z., Koenen, R. R., Heyll, K., Gremse, F., Kiessling, F., Grommes, J., Weber, C., & Schober, A. (2012). MicroRNA-155 promotes atherosclerosis by repressing Bcl6 in macrophages. Journal of Clinical Investigation, 122(11), 4190-4202. https://doi.org/10.1172/JCI61716
    • Willemsen, S., Hartog, J. W. L., van Veldhuisen, D. J., van der Meer, P., Roze, J. F., Jaarsma, T., Schalkwijk, C., van der Horst, I. C. C., Hillege, H. L., & Voors, A. A. (2012). The role of advanced glycation end-products and their receptor on outcome in heart failure patients with preserved and reduced ejection fraction. American Heart Journal, 164(5), 742-U146. https://doi.org/10.1016/j.ahj.2012.07.027
    • Compeer, M. G., Suylen, D. P. L., Hackeng, T. M., & De Mey, J. G. R. (2012). Endothelin-1 and-2: Two amino acids matter. Life Sciences, 91(13-14), 607-612. https://doi.org/10.1016/j.lfs.2012.02.011
    • Yang, J., Loos, R. J. F., Powell, J. E., Medland, S. E., Speliotes, E. K., Chasman, D. I., Rose, L. M., Thorleifsson, G., Steinthorsdottir, V., Maegi, R., Waite, L. L., Smith, A. V., Yerges-Armstrong, L. M., Monda, K. L., Hadley, D., Mahajan, A., Li, G., Kapur, K., Vitart, V., ... Visscher, P. M. (2012). FTO genotype is associated with phenotypic variability of body mass index. Nature, 490(7419), 267–272. https://doi.org/10.1038/nature11401
    • Geersing, G.-J., Erkens, P. M. G., Lucassen, W. A. M., Buller, H. R., ten Cate, H., Hoes, A. W., Moons, K. G. M., Prins, M. H., Oudega, R., van Weert, H. C. P. M., & Stoffers, H. E. J. H. (2012). Safe exclusion of pulmonary embolism using the Wells rule and qualitative D-dimer testing in primary care: prospective cohort study. BMJ, 345(7880), Article e6564. https://doi.org/10.1136/bmj.e6564
    • Amin, N., Schuur, M., Gusareva, E. S., Isaacs, A., Aulchenko, Y. S., Kirichenko, A. V., Zorkoltseva, I. V., Axenovich, T. I., Oostra, B. A., Janssens, A. C. J. W., & van Duijn, C. M. (2012). A genome-wide linkage study of individuals with high scores on NEO personality traits. Molecular Psychiatry, 17(10), 1031-41. https://doi.org/10.1038/mp.2011.97
    • Talens, S., Malfliet, J. J. M. C., Rudez, G., Spronk, H. M. H., Janssen, N. A. H., Meijer, P., Kluft, C., de Maat, M. P. M., & Rijken, D. C. (2012). Biological variation in tPA-induced plasma clot lysis time. Thrombosis and Haemostasis, 108(4), 640-646. https://doi.org/10.1160/TH12-02-0124
    • van der Meijden, P. E. J., Feijge, M. A. H., Swieringa, F., Gilio, K., Nergiz-Unal, R., Hamulyak, K., & Heemskerk, J. W. M. (2012). Key role of integrin alpha(IIb)beta(3) signaling to Syk kinase in tissue factor-induced thrombin generation. Cellular and Molecular Life Sciences, 69(20), 3481-3492. https://doi.org/10.1007/s00018-012-1033-2
    • Erkens, P. M. G., ten Cate, H., Buller, H. R., & Prins, M. H. (2012). Benchmark for Time in Therapeutic Range in Venous Thromboembolism: A Systematic Review and Meta-Analysis. PLOS ONE, 7(9), Article e42269. https://doi.org/10.1371/journal.pone.0042269
    • Scott, R. A., Lagou, V., Welch, R. P., Wheeler, E., Montasser, M. E., Luan, J., Mägi, R., Strawbridge, R. J., Rehnberg, E., Gustafsson, S., Kanoni, S., Rasmussen-Torvik, L. J., Yengo, L., Lecoeur, C., Shungin, D., Sanna, S., Sidore, C., Johnson, P. C. D., Jukema, J. W., ... Barroso, I. (2012). Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways. Nature Genetics, 44(9), 991-1005. https://doi.org/10.1038/ng.2385
    • Lance, M. D., Kuiper, G. J. A. J. M., Sloep, M., Spronk, H. M. H., van Oerle, R., ten Cate, H., Marcus, M. A. E., & Henskens, Y. M. C. (2012). The effects of pneumatic tube system transport on ROTEM analysis and contact activation assessed by thrombin generation test. Thrombosis Research, 130(3), E147-E150. https://doi.org/10.1016/j.thromres.2012.05.002
    • Mingels, A. M., Cobbaert, C. M., de Jong, N., van den Hof, W. F., & van Dieijen-Visser, M. P. (2012). Time- and temperature-dependent stability of troponin standard reference material 2921 in serum and plasma. Clinical Chemistry and Laboratory Medicine, 50(9), 1681-1684. https://doi.org/10.1515/cclm-2011-1851
    • Marchetti, M., Diani, E., ten Cate, H., & Falanga, A. (2012). Characterization of the thrombin generation potential of leukemic and solid tumor cells by calibrated automated thrombography. Haematologica-the Hematology Journal, 97(8), 1173-1180. https://doi.org/10.3324/haematol.2011.055343
    • Bouman, A. C., Smits, J., Ten Cate, H., & Ten Cate-Hoek, A. J. (2012). Markers of coagulation, fibrinolysis and inflammation in relation to post-thrombotic syndrome. Journal of Thrombosis and Haemostasis, 10(8), 1532-1538. https://doi.org/10.1111/j.1538-7836.2012.04798.x
    • Peraramelli, S., Suylen, D. P. L., Rosing, J., & Hackeng, T. M. (2012). The Kunitz 1 and Kunitz 3 domains of tissue factor pathway inhibitor are required for efficient inhibition of factor Xa. Thrombosis and Haemostasis, 108(2), 266-276. https://doi.org/10.1160/TH11-12-0902
    • Durik, M., Kavousi, M., van der Pluijm, I., Isaacs, A., Cheng, C., Verdonk, K., Loot, A. E., Oeseburg, H., Bhaggoe, U. M., Leijten, F., van Veghel, R., de Vries, R., Rudez, G., Brandt, R., Ridwan, Y. R., van Deel, E. D., de Boer, M., Tempel, D., Fleming, I., ... Roks, A. J. M. (2012). Nucleotide excision DNA repair is associated with age-related vascular dysfunction. Circulation, 126(4), 468-78. https://doi.org/10.1161/CIRCULATIONAHA.112.104380
    • Compeer, M. G., Meens, M. J. P. M. T., Hackeng, T. M., Neugebauer, W. A., Hoeltke, C., & De Mey, J. G. R. (2012). Agonist-dependent modulation of arterial endothelinA receptor function. British Journal of Pharmacology, 166(6), 1833-1845. https://doi.org/10.1111/j.1476-5381.2012.01896.x
    • van Kruchten, R., Braun, A., Feijge, M. A. H., Kuijpers, M. J. E., Rivera-Galdos, R., Kraft, P., Stoll, G., Kleinschnitz, C., Bevers, E. M., Nieswandt, B., & Heemskerk, J. W. M. (2012). Antithrombotic Potential of Blockers of Store-Operated Calcium Channels in Platelets. Arteriosclerosis Thrombosis and Vascular Biology, 32(7), 1717-1723. https://doi.org/10.1161/ATVBAHA.111.243907
    • van Gerven, P. W. M., van Boxtel, M. P. J., Ausems, E. E. B., Bekers, O., & Jolles, J. (2012). Do apolipoprotein E genotype and educational attainment predict the rate of cognitive decline in normal aging? A 12-year follow-up of the Maastricht Aging Study. Neuropsychology, 26(4), 459-472. https://doi.org/10.1037/a0028685
    • Doering, Y., Soehnlein, O., Drechsler, M., Shagdarsuren, E., Chaudhari, S. M., Meiler, S., Hartwig, H., Hristov, M., Koenen, R. R., Hieronymus, T., Zenke, M., Weber, C., & Zernecke, A. (2012). Hematopoietic Interferon Regulatory Factor 8-Deficiency Accelerates Atherosclerosis in Mice. Arteriosclerosis Thrombosis and Vascular Biology, 32(7), 1613-1623. https://doi.org/10.1161/ATVBAHA.111.236539
    • van de Laar, R. J. J., Stehouwer, C. D. A., van Bussel, B. C. T., te Velde, S. J., Prins, M. H., Twisk, J. W., & Ferreira, I. (2012). Lower lifetime dietary fiber intake is associated with carotid artery stiffness: the Amsterdam Growth and Health Longitudinal Study. American Journal of Clinical Nutrition, 96(1), 14-23. https://doi.org/10.3945/ajcn.111.024703
    • Nur, E., Brandjes, D. P., Teerlink, T., Otten, H.-M., Elferink, R. P. J. O., Muskiet, F., Evers, L. M., ten Cate, H., Biemond, B. J., Duits, A. J., & Schnog, J.-J. B. (2012). N-acetylcysteine reduces oxidative stress in sickle cell patients. Annals of Hematology, 91(7), 1097-1105. https://doi.org/10.1007/s00277-011-1404-z
    • de Lange, N. M., Lance, M. D., de Groot, R., Beckers, E. A. M., Henskens, Y. M., & Scheepers, H. C. J. (2012). Obstetric Hemorrhage and Coagulation: An Update. Thromboelastography, Thromboelastometry, and Conventional Coagulation Tests in the Diagnosis and Prediction of Postpartum Hemorrhage. Obstetrical & Gynecological Survey, 67(7), 426-435. https://doi.org/10.1097/OGX.0b013e3182605861
    • Lance, M. D., Ninivaggi, M., Schols, S. E. M., Feijge, M. A. H., Oehrl, S. K., Kuiper, G. J. A. J. M., Nikiforou, M., Marcus, M. A. E., Hamulyak, K., van Pampus, E. C. M., ten Cate, H., & Heemskerk, J. W. M. (2012). Perioperative dilutional coagulopathy treated with fresh frozen plasma and fibrinogen concentrate: a prospective randomized intervention trial. Vox Sanguinis, 103(1), 25-34. https://doi.org/10.1111/j.1423-0410.2011.01575.x
    • van der Meijden, P. E. J., van Schilfgaarde, M., van Oerle, R., Renne, T., ten Cate, H., & Spronk, H. M. H. (2012). Platelet- and erythrocyte-derived microparticles trigger thrombin generation via factor XIIa. Journal of Thrombosis and Haemostasis, 10(7), 1355-1362. https://doi.org/10.1111/j.1538-7836.2012.04758.x
    • Lance, M. D., Marcus, M. A. E., van Oerle, R., Theunissen, H. M. S., & Henskens, Y. M. C. (2012). Platelet concentrate transport in pneumatic tube systems - does it work?Vox Sanguinis, 103(1), 79-82. https://doi.org/10.1111/j.1423-0410.2011.01580.x
    • Loeffen, R., Spronk, H. M. H., & ten Cate, H. (2012). The impact of blood coagulability on atherosclerosis and cardiovascular disease. Journal of Thrombosis and Haemostasis, 10(7), 1207-1216. https://doi.org/10.1111/j.1538-7836.2012.04782.x
    • Chatrou, M. L. L., Winckers, K., Hackeng, T. M., Reutelingsperger, C. P. M., & Schurgers, L. J. (2012). Vascular calcification: The price to pay for anticoagulation therapy with vitamin K-antagonists. Blood Reviews, 26(4), 155-166. https://doi.org/10.1016/j.blre.2012.03.002
    • Klinkenberg, L. J., Res, P. T., van Loon, L. J. C., van Dieijen-Visser, M. P., & Meex, S. J. R. (2012). Strong link between basal and exercise-induced cardiac troponin T levels: Do both reflect risk?International Journal of Cardiology, 158(1), 129-131. https://doi.org/10.1016/j.ijcard.2012.04.050
    • Sanders, M. P. A., Barbosa, A. J. M., Zarzycka, B., Nicolaes, G. A. F., Klomp, J. P. G., de Vlieg, J., & Del Rio, A. (2012). Comparative Analysis of Pharmacophore Screening Tools. Journal of Chemical Information and Modeling, 52(6), 1607-1620. https://doi.org/10.1021/ci2005274
    • Hanssen, S. J. P., van de Poll, M. C. G., Houben, A. J., Vermeulen Windsant, I. C., Snoeijs, M. G., Bekers, O., Buurman, W. A., & Jacobs, M. J. H. M. (2012). Hemolysis compromises nitric oxide-dependent vasodilatory responses in patients undergoing major cardiovascular surgery.Thoracic and Cardiovascular Surgeon, 60(4), 255-261. https://doi.org/10.1055/s-0031-1299571
    • Raps, M., Helmerhorst, F., Fleischer, K., Thomassen, S., Rosendaal, F., Rosing, J., Ballieux, B., & Van Vliet, H. (2012). Sex hormone-binding globulin as a marker for the thrombotic risk of hormonal contraceptives. Journal of Thrombosis and Haemostasis, 10(6), 992-997. https://doi.org/10.1111/j.1538-7836.2012.04720.x
    • Cardinaels, E. P., Mingels, A. M., Jacobs, L. H., Meex, S. J., Bekers, O., & van Dieijen-Visser, M. P. (2012). A comprehensive review of upper reference limits reported for (high-)sensitivity cardiac troponin assays: The challenges that lie ahead. Clinical Chemistry and Laboratory Medicine, 50(5), 791-806. https://doi.org/10.1515/cclm-2011-0895
    • Postea, O., Vasina, E. M., Cauwenberghs, S., Projahn, D., Liehn, E. A., Lievens, D., Theelen, W., Kramp, B. K., Butoi, E. D., Soehnlein, O., Heemskerk, J. W. M., Ludwig, A., Weber, C., & Koenen, R. R. (2012). Contribution of Platelet CX(3)CR1 to Platelet-Monocyte Complex Formation and Vascular Recruitment During Hyperlipidemia. Arteriosclerosis Thrombosis and Vascular Biology, 32(5), 1186-1193. https://doi.org/10.1161/ATVBAHA.111.243485
    • Beijers, H. J. B. H., Ferreira, I., Spronk, H. M. H., Bravenboer, B., Dekker, J. M., Nijpels, G., ten Cate, H., & Stehouwer, C. D. A. (2012). Impaired glucose metabolism and type 2 diabetes are associated with hypercoagulability: potential role of central adiposity and low-grade inflammation - The Hoorn Study. Thrombosis Research, 129(5), 557-562. https://doi.org/10.1016/j.thromres.2011.07.033