• 2014
    • Wood, A. R., Esko, T., Yang, J., Vedantam, S., Pers, T. H., Gustafsson, S., Chu, A. Y., Estrada, K., Luan, J., Kutalik, Z., Amin, N., Buchkovich, M. L., Croteau-Chonka, D. C., Day, F. R., Duan, Y., Fall, T., Fehrmann, R., Ferreira, T., Jackson, A. U., ... Frayling, T. M. (2014). Defining the role of common variation in the genomic and biological architecture of adult human height. Nature Genetics, 46(11), 1173-86. https://doi.org/10.1038/ng.3097
    • Schurgers, L. J., & Spronk, H. M. H. (2014). Differential cellular effects of old and new oral anticoagulants: consequences to the genesis and progression of atherosclerosis. Thrombosis and Haemostasis, 112(5), 909-917. https://doi.org/10.1160/TH14-03-0268
    • Peraramelli, S., Thomassen, S., Heinzmann, A., Rosing, J., Hackeng, T. M., Hartmann, R., Scheiflinger, F., & Dockal, M. (2014). Inhibition of tissue factor: factor VIIa-catalyzed factor IX and factor X activation by TFPI and TFPI constructs. Journal of Thrombosis and Haemostasis, 12(11), 1826-1837. https://doi.org/10.1111/jth.12713
    • van IJzendoorn, M. C. O., Koopmans, M., Strauch, U., Heines, S., den Boer, S., Kors, B. M., van der Voort, P. H. J., Dennesen, P. J. W., van den Hul, I., Alberts, E., Egbers, P., Esteban, A., Frutos-Vivar, F., & Kuiper, M. A. (2014). Ventilator setting in ICUs: comparing a Dutch with a European cohort. Netherlands Journal of Medicine, 72(9), 473-480.
    • Benyamin, B., Esko, T., Ried, J. S., Radhakrishnan, A., Vermeulen, S. H., Traglia, M., Gögele, M., Anderson, D., Broer, L., Podmore, C., Luan, J., Kutalik, Z., Sanna, S., van der Meer, P., Tanaka, T., Wang, F., Westra, H.-J., Franke, L., Mihailov, E., ... Whitfield, J. B. (2014). Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis. Nature Communications, 5, 4926. https://doi.org/10.1038/ncomms5926
    • Kleinegris, M. C., Bos, M. H., Roest, M., Henskens, Y., Ten Cate-Hoek, A., Van Deursen, C., Spronk, H. M., Reitsma, P. H., De Groot, P. G., ten Cate, H., & Koek, G. (2014). Cirrhosis patients have a coagulopathy that is associated with decreased clot formation capacity. Journal of Thrombosis and Haemostasis, 12(10), 1647-1657. https://doi.org/10.1111/jth.12706
    • Nagler, M., & ten Cate, H. (2014). Thromboelastometry changes in myeloproliferative neoplasms-surrogate for a procoagulant haemostatic imbalance or a consequence of technical reasons? Comment on A-Tripodi et al. Ann Hematol (2013) 92:1633-1639. Annals of Hematology, 93(10), 1781-1782. https://doi.org/10.1007/s00277-014-2059-3
    • Studer, R. A., Opperdoes, F. R., Nicolaes, G. A. F., Mulder, A. B., & Mulder, R. (2014). Understanding the functional difference between growth arrest-specific protein 6 and protein S: an evolutionary approach. Open Biology, 4(10), Article 140121. https://doi.org/10.1098/rsob.140121
    • Venema, L. H., Sharma, A. S., Simons, A. P., Bekers, O., & Weerwind, P. W. (2014). Contemporary Oxygenator Design Relative to Hemolysis. Journal of ExtraCorporeal Technology, 46(3), 212-6. https://doi.org/10.1051/ject/201446212
    • Bot, I., Daissormont, I. T. M. N., Zernecke, A., van Puijvelde, G. H. M., Kramp, B., de Jager, S. C. A., Sluimer, J. C., Manca, M., Herias, V., Westra, M. M., Bot, M., van Santbrink, P. J., van Berkel, T. J. C., Su, L., Skjelland, M., Gullestad, L., Kuiper, J., Halvorsen, B., Aukrust, P., ... Biessen, E. A. L. (2014). CXCR4 blockade induces atherosclerosis by affecting neutrophil function. Journal of Molecular and Cellular Cardiology, 74, 44-52. https://doi.org/10.1016/j.yjmcc.2014.04.021
    • van Ryn, J., Grottke, O., & Spronk, H. (2014). Measurement of dabigatran in standardly used clinical assays, whole blood viscoelastic coagulation, and thrombin generation assays. Clinics in Laboratory Medicine, 34(3), 479-501. https://doi.org/10.1016/j.cll.2014.06.008
    • Omarova, F., de Willige, S. U., Simioni, P., Ariens, R. A. S., Bertina, R. M., Rosing, J., & Castoldi, E. (2014). Fibrinogen gamma ' increases the sensitivity to activated protein C in normal and factor V Leiden plasma. Blood, 124(9), 1531-1538. https://doi.org/10.1182/blood-2014-02-554055
    • Kapsokalyvas, D., Schiffers, P. M. H., Maij, N., Suylen, D. P., Hackeng, T. M., van Zandvoort, M. A. M. J., & De Mey, J. G. R. (2014). Imaging evidence for endothelin ETA/ETB receptor heterodimers in isolated rat mesenteric resistance arteries. Life Sciences, 111(1-2), 36-41. https://doi.org/10.1016/j.lfs.2014.07.007
    • Kuijpers, M. J. E., van der Meijden, P. E. J., Feijge, M. A. H., Mattheij, N. J. A., May, F., Govers-Riemslag, J., Meijers, J. C. M., Heemskerk, J. W. M., Renne, T., & Cosemans, J. M. E. M. (2014). Factor XII Regulates the Pathological Process of Thrombus Formation on Ruptured Plaques. Arteriosclerosis Thrombosis and Vascular Biology, 34(8), 1674–1680. https://doi.org/10.1161/ATVBAHA.114.303315
    • van Montfoort, M. L., Kuijpers, M. J. E., Knaup, V. L., Bhanot, S., Monia, B. P., Roelofs, J. J. T. H., Heemskerk, J. W. M., & Meijers, J. C. M. (2014). Factor XI Regulates Pathological Thrombus Formation on Acutely Ruptured Atherosclerotic Plaques. Arteriosclerosis Thrombosis and Vascular Biology, 34(8), 1668–1673. https://doi.org/10.1161/ATVBAHA.114.303209
    • Arking, D. E., Pulit, S. L., Crotti, L., van der Harst, P., Munroe, P. B., Koopmann, T. T., Sotoodehnia, N., Rossin, E. J., Morley, M., Wang, X., Johnson, A. D., Lundby, A., Gudbjartsson, D. F., Noseworthy, P. A., Eijgelsheim, M., Bradford, Y., Tarasov, K. V., Dörr, M., Müller-Nurasyid, M., ... Newton-Cheh, C. H. (2014). Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization. Nature Genetics, 46(8), 826-36. https://doi.org/10.1038/ng.3014
    • van der Linden, N., Klinkenberg, L. J. J., Meex, S. J. R., Beckers, E. A. M., de Wit, N. C. J., & Prinzen, L. (2014). Immature platelet fraction measured on the Sysmex XN hemocytometer predicts thrombopoietic recovery after autologous stem cell transplantation. European Journal of Haematology, 93(2), 150-156. https://doi.org/10.1111/ejh.12319
    • Ninivaggi, M., Kelchtermans, H., Kuijpers, M. J., Hemmeryckx, B., Heemskerk, J. W. M., Lindhout, T., Hoylaerts, M. F., & de Laat, B. (2014). Whole blood thrombin generation in Bmal1-deficient mice. Thrombosis and Haemostasis, 112(2), 271-275. https://doi.org/10.1160/TH13-11-0910
    • Wildhagen, K. C. A. A., Schrijver, R., Beckers, L., ten Cate, H., Reutelingsperger, C. P. M., Lutgens, E., & Nicolaes, G. A. F. (2014). Effects of Exogenous Recombinant APC in Mouse Models of Ischemia Reperfusion Injury and of Atherosclerosis. PLOS ONE, 9(7), Article e101446. https://doi.org/10.1371/journal.pone.0101446
    • Angin, Y., Schwenk, R. W., Nergiz-Unal, R., Hoebers, N., Heemskerk, J. W. M., Kuijpers, M. J., Coumans, W. A., van Zandvoort, M. A. M. J., Bonen, A., Neumann, D., Glatz, J. F. C., & Luiken, J. (2014). Calcium signaling recruits substrate transporters GLUT4 and CD36 to the sarcolemma without increasing cardiac substrate uptake. American Journal of Physiology : Endocrinology and Metabolism, 307(2), E225-E236. https://doi.org/10.1152/ajpendo.00655.2013
    • de Witt, S. M., Swieringa, F., Cavill, R., Lamers, M. M., van Kruchten, R., Mastenbroek, T., Baaten, C., Coort, S., Pugh, N., Schulz, A., Scharrer, I., Jurk, K., Zieger, B., Clemetson, K. J., Farndale, R. W., Heemskerk, J. W., & Cosemans, J. M. (2014). Identification of platelet function defects by multi-parameter assessment of thrombus formation. Nature Communications, 5, Article 4257. https://doi.org/10.1038/ncomms5257
    • Schmitt, M. M. N., Fraemohs, L., Hackeng, T. M., Weber, C., & Koenen, R. R. (2014). Atherogenic mononuclear cell recruitment is facilitated by oxidized lipoprotein-induced endothelial junctional adhesion molecule-A redistribution. Atherosclerosis, 234(2), 254-264. https://doi.org/10.1016/j.atherosclerosis.2014.03.014
    • Streng, A. S., Jacobs, L. H. J., Schwenk, R. W., Cardinaels, E. P. M., Meex, S. J. R., Glatz, J. F. C., Wodzig, W. K. W. H., & van Dieijen-Visser, M. P. (2014). Cardiac troponin in ischemic cardiomyocytes: Intracellular decrease before onset of cell death. Experimental and Molecular Pathology, 96(3), 339-345. https://doi.org/10.1016/j.yexmp.2014.02.012
    • Nagler, M., ten Cate, H., Kathriner, S., Casutt, M., Bachmann, L. M., & Wuillemin, W. A. (2014). Consistency of thromboelastometry analysis under scrutiny: Results of a systematic evaluation within and between analysers. Thrombosis and Haemostasis, 111(6), 1161-1166. https://doi.org/10.1160/TH13-10-0870
    • Sperandio, O., Wildhagen, K. C. A. A., Schrijver, R., Wielders, S., Villoutreix, B. O., & Nicolaes, G. A. F. (2014). Identification of novel small molecule inhibitors of activated protein C. Thrombosis Research, 133(6), 1105-1114. https://doi.org/10.1016/j.thromres.2014.01.026
    • Shadid, N. H., van der Velden, S. K., van Oerle, R., ten Cate, H., Sommer, A., & Nelemans, P. (2014). In vivo effects of foam sclerotherapy on coagulation. Phlebology: The Journal of Venous Disease, 29(5), 287-292. https://doi.org/10.1177/0268355513479590
    • Posthuma, J. J., Loeffen, R., van Oerle, R., Henskens, Y. M. C., ten Cate, H., Spronk, H. M. H., & van der Meijden, P. E. J. (2014). Long-term strenuous exercise induces a hypercoagulable state through contact activation. Thrombosis and Haemostasis, 111(6), 1197-1199. https://doi.org/10.1160/TH13-11-0963
    • Kuijpers, M. J. E., de Witt, S., Nergiz-Unal, R., van Kruchten, R., Korporaal, S. J. A., Verhamme, P., Febbraio, M., Tjwa, M., Voshol, P. J., Hoylaerts, M. F., Cosemans, J. M. E. M., & Heemskerk, J. W. M. (2014). Supporting Roles of Platelet Thrombospondin-1 and CD36 in Thrombus Formation on Collagen. Arteriosclerosis Thrombosis and Vascular Biology, 34(6), 1187-1192. https://doi.org/10.1161/ATVBAHA.113.302917
    • Projahn, D., Simsekyilmaz, S., Singh, S., Kanzler, I., Kramp, B. K., Langer, M., Burlacu, A., Bernhagen, J., Klee, D., Zernecke, A., Hackeng, T. M., Groll, J., Weber, C., Liehn, E. A., & Koenen, R. R. (2014). Controlled intramyocardial release of engineered chemokines by biodegradable hydrogels as a treatment approach of myocardial infarction. Journal of Cellular and Molecular Medicine, 18(5), 790-800. https://doi.org/10.1111/jcmm.12225
    • Spronk, H. M. H., ten Cate, H., & van der Meijden, P. E. J. (2014). Differential roles of Tissue Factor and Phosphatidylserine in activation of coagulation. Thrombosis Research, 133(SUPPL. 1), S54-S56. https://doi.org/10.1016/j.thromres.2014.03.022
    • de Witt, S. M., Verdoold, R., Cosemans, J. M. E. M., & Heemskerk, J. W. M. (2014). Insights into platelet-based control of coagulation. Thrombosis Research, 133(SUPPL. 2), S139-S148. https://doi.org/10.1016/S0049-3848(14)50024-2
    • ten Cate, H., & Meade, T. (2014). The Northwick Park Heart Study: evidence from the laboratory. Journal of Thrombosis and Haemostasis, 12(5), 587-592. https://doi.org/10.1111/jth.12545
    • Castoldi, E. (2014). FV and APC resistance: the plot thickens. Blood, 123(15), 2288-2289. https://doi.org/10.1182/blood-2014-02-557363
    • Vlassaks, E., Nikiforou, M., Strackx, E., Hutten, M., Bekers, O., Gazzolo, D., Li Volti, G., Martinez-Martinez, P., Kramer, B. W., & Gavilanes, A. W. (2014). Acute and chronic immunomodulatory changes in rat liver after fetal and perinatal asphyxia. Journal of developmental origins of health and disease, 5(2), 98-108. https://doi.org/10.1017/S2040174413000561
    • Koenen, R. R. (2014). CX(3)CL1, a special deputy at the intersection of platelets and the vessel wall. Thrombosis and Haemostasis, 111(4), 567-567. https://doi.org/10.1160/TH14-02-0173
    • Kok, M., Mihl, C., Mingels, A. A., Kietselaer, B. L., Muhlenbruch, G., Seehofnerova, A., Wildberger, J. E., & Das, M. (2014). Influence of Contrast Media Viscosity and Temperature on Injection Pressure in Computed Tomographic Angiography A Phantom Study. Investigative Radiology, 49(4), 217-223. https://doi.org/10.1097/RLI.0000000000000019
    • Eijgenraam, P., ten Cate, H., & ten Cate-Hoek, A. J. (2014). Practice of bridging anticoagulation: guideline adherence and risk factors for bleeding. Netherlands Journal of Medicine, 72(3), 157-164.
    • Olde Engberink, R. H. G., Kuiper, G. J. A. J. M., Wetzels, R. J. H., Nelemans, P. J., Lance, M. D., Beckers, E. A. M., & Henskens, Y. M. C. (2014). Rapid and Correct Prediction of Thrombocytopenia and Hypofibrinogenemia With Rotational Thromboelastometry in Cardiac Surgery. Journal of Cardiothoracic and Vascular Anesthesia, 28(2), 210-216. https://doi.org/10.1053/j.jvca.2013.12.004
    • Raps, M., Curvers, J., Helmerhorst, F. M., Ballieux, B. E. P. B., Rosing, J., Thomassen, S., Rosendaal, F. R., & van Vliet, H. A. A. M. (2014). Thyroid function, activated protein C resistance and the risk of venous thrombosis in users of hormonal contraceptives. Thrombosis Research, 133(4), 640-644. https://doi.org/10.1016/j.thromres.2013.12.041
    • Chatzigeorgiou, A., Seijkens, T., Zarzycka, B., Engel, D., Poggi, M., van den Berg, S., van den Berg, S., Soehnlein, O., Winkels, H., Beckers, L., Lievens, D., Driessen, A., Kusters, P., Biessen, E., Garcia-Martin, R., Klotzsche-von Ameln, A., Gijbels, M., Noelle, R., Boon, L., ... Lutgens, E. (2014). Correction for Chatzigeorgiou et al., Blocking CD40-TRAF6 signaling is a therapeutic target in obesity-associated insulin resistance (vol 111, pg 2686, 2014). Proceedings of the National Academy of Sciences of the United States of America, 111(12), 4644-4644. https://doi.org/10.1073/pnas.1403231111
    • Li, X., Zhu, M., Penfold, M. E., Koenen, R. R., Thiemann, A., Heyll, K., Akhtar, S., Koyadan, S., Wu, Z., Gremse, F., Kiessling, F., van Zandvoort, M., Schall, T. J., Weber, C., & Schober, A. (2014). Activation of CXCR7 Limits Atherosclerosis and Improves Hyperlipidemia by Increasing Cholesterol Uptake in Adipose Tissue. Circulation, 129(11), 1244-1253. https://doi.org/10.1161/CIRCULATIONAHA.113.006840
    • Geersing, G. J., Zuithoff, N. P. A., Kearon, C., Anderson, D. R., ten Cate-Hoek, A. J., Elf, J. L., Bates, S. M., Hoes, A. W., Kraaijenhagen, R. A., Oudega, R., Schutgens, R. E. G., Stevens, S. M., Woller, S. C., Wells, P. S., & Moons, K. G. M. (2014). Exclusion of deep vein thrombosis using the Wells rule in clinically important subgroups: individual patient data meta-analysis. BMJ, 348, Article g1340. https://doi.org/10.1136/bmj.g1340
    • Hoek - ten Cate, A. (2014). Elastic compression stockings-is there any benefit?Lancet, 383(9920), 851-853. https://doi.org/10.1016/S0140-6736(13)62347-8
    • Tragante, V., Barnes, M. R., Ganesh, S. K., Lanktree, M. B., Guo, W., Franceschini, N., Smith, E. N., Johnson, T., Holmes, M. V., Padmanabhan, S., Karczewski, K. J., Almoguera, B., Barnard, J., Baumert, J., Chang, Y.-P. C., Elbers, C. C., Farrall, M., Fischer, M. E., Gaunt, T. R., ... Keating, B. J. (2014). Gene-centric meta-analysis in 87,736 individuals of European ancestry identifies multiple blood-pressure-related loci. American Journal of Human Genetics, 94(3), 349-60. https://doi.org/10.1016/j.ajhg.2013.12.016
    • Geenen, I. L., Verbruggen, S., Molin, D. G., Spronk, H. M., Maessen, J. G., Meesters, B., Schurink, G. W., & Post, M. J. (2014). Phenotypic Fitness of Primary Endothelial Cells Cultured from Patients with High Cardiovascular Risk or Chronic Kidney Disease for Vascular Tissue Engineering. Tissue Engineering, 20(5-6), 1049-1059. https://doi.org/10.1089/ten.tea.2013.0163
    • Spronk, H. M. H., de Jong, A. M., Crijns, H. J., Schotten, U., Van Gelder, I. C., & ten Cate, H. (2014). Pleiotropic effects of factor Xa and thrombin: what to expect from novel anticoagulants. Cardiovascular Research, 101(3), 344-351. https://doi.org/10.1093/cvr/cvt343
    • Ninivaggi, M., Feijge, M. A. H., Baaten, C. C. F. M. J., Kuiper, G. J. A. J. M., Marcus, M. A. E., ten Cate, H., Lance, M. D., Heemskerk, J. W. M., & van der Meijden, P. E. J. (2014). Additive roles of platelets and fibrinogen in whole-blood fibrin clot formation upon dilution as assessed by thromboelastometry. Thrombosis and Haemostasis, 111(3), 447-457. https://doi.org/10.1160/TH13-06-0493
    • Segers, O., Simioni, P., Tormene, D., & Castoldi, E. (2014). Influence of single nucleotide polymorphisms on thrombin generation in factor V Leiden heterozygotes. Thrombosis and Haemostasis, 111(3), 438-446. https://doi.org/10.1160/TH13-05-0360
    • Bosch, Y. P. J., al Dieri, R., ten Cate, H., Nelemans, P. J., Bloemen, S., de Laat, B., Hemker, C., Weerwind, P. W., Maessen, J. G., & Mochtar, B. (2014). Measurement of thrombin generation intra-operatively and its association with bleeding tendency after cardiac surgery. Thrombosis Research, 133(3), 488-494. https://doi.org/10.1016/j.thromres.2013.12.017
    • Pop, A. S., Levenga, J., de Esch, C. E. F., Buijsen, R. A. M., Nieuwenhuizen, I. M., Li, T., Isaacs, A., Gasparini, F., Oostra, B. A., & Willemsen, R. (2014). Rescue of dendritic spine phenotype in Fmr1 KO mice with the mGluR5 antagonist AFQ056/Mavoglurant. Psychopharmacology, 231(6), 1227-35. https://doi.org/10.1007/s00213-012-2947-y