• 2017
    • Panova-Noeva, M., Arnold, N., Hermanns, M. I., Prochaska, J. H., Schulz, A., Spronk, H. M., Binder, H., Pfeiffer, N., Beutel, M., Blankenberg, S., Zeller, T., Lotz, J., Muenzel, T., Lackner, K. J., ten Cate, H., & Wild, P. S. (2017). Mean Platelet Volume and Arterial Stiffness - Clinical Relationship and Common Genetic Variability. Scientific Reports, 7, Article 40229. https://doi.org/10.1038/srep40229
    • Carss, K. J., Arno, G., Erwood, M., Stephens, J., Sanchis-Juan, A., Hull, S., Megy, K., Grozeva, D., Dewhurst, E., Malka, S., Plagnol, V., Penkett, C., Stirrups, K., Rizzo, R., Wright, G., Josifova, D., Bitner-Glindzicz, M., Scott, R. H., Clement, E., ... Raymond, F. L. (2017). Comprehensive Rare Variant Analysis via Whole-Genome Sequencing to Determine the Molecular Pathology of Inherited Retinal Disease. American Journal of Human Genetics, 100(1), 75-90. https://doi.org/10.1016/j.ajhg.2016.12.003
    • Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity, Chambers, J. C., Grallert, H., & Kooner, J. S. (2017). Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity. Nature, 541(7635), 81-86. https://doi.org/10.1038/nature20784
    • Spronk, H. M. H., De Jong, A. M., Verheule, S., De Boer, H. C., Maass, A. H., Lau, D. H., Rienstra, M., van Hunnik, A., Kuiper, M., Lumeij, S., Zeemering, S., Linz, D., Kamphuisen, P. W., ten Cate, H., Crijns, H. J., Van Gelder, I. C., van Zonneveld, A. J., & Schotten, U. (2017). Hypercoagulability causes atrial fibrosis and promotes atrial fibrillation. European Heart Journal, 38(1), 38-50. https://doi.org/10.1093/eurheartj/ehw119
    • van Dooren, F. E. P., Pouwer, F., Schalkwijk, C. G., Sep, S. J. S., Stehouwer, C. D. A., Henry, R. M. A., Dagnelie, P. C., Schaper, N. C., van der Kallen, C. J. H., Koster, A., Denollet, J., Verhey, F. R. J., & Schram, M. T. (2017). Advanced Glycation End Product (AGE) Accumulation in the Skin is Associated with Depression: The Maastricht Study. Depression and Anxiety, 34(1), 59-67. https://doi.org/10.1002/da.22527
    • Kusters, R. W. J., Simons, A. P., Lance, M. D., Ganushchak, Y. M., Bekers, O., & Weerwind, P. W. (2017). Blood warming, pump heating and haemolysis in low-flow extracorporeal life support; an in vitro study using freshly donated human blood. Perfusion, 32(1), 27-34. https://doi.org/10.1177/0267659116656045
    • Vries, M. J. A., Bouman, H. J., Olie, R. H., Veenstra, L. F., Zwaveling, S., Verhezen, P. W. M., ten Cate-Hoek, A. J., ten Cate, H., Henskens, Y. M. C., & van der Meijden, P. E. J. (2017). Determinants of agreement between proposed therapeutic windows of platelet function tests in vulnerable patients. European Heart Journal-Cardiovascular Pharmacotherapy, 3(1), 11-17. https://doi.org/10.1093/ehjcvp/pvw026
    • Bonder, M. J., Luijk, R., Zhernakova, D. V., Moed, M., Deelen, P., Vermaat, M., van Iterson, M., van Dijk, F., van Galen, M., Bot, J., Slieker, R. C., Jhamai, P. M., Verbiest, M., Suchiman, H. E. D., Verkerk, M., van der Breggen, R., van Rooij, J., Lakenberg, N., Arindrarto, W., ... Franke, L. (2017). Disease variants alter transcription factor levels and methylation of their binding sites. Nature Genetics, 49(1), 131-138. https://doi.org/10.1038/ng.3721
    • Zhernakova, D. V., Deelen, P., Vermaat, M., van Iterson, M., van Galen, M., Arindrarto, W., van 't Hof, P., Mei, H., van Dijk, F., Westra, H.-J., Bonder, M. J., van Rooij, J., Verkerk, M., Jhamai, P. M., Moed, M., Kielbasa, S. M., Bot, J., Nooren, I., Pool, R., ... Franke, L. (2017). Identification of context-dependent expression quantitative trait loci in whole blood. Nature Genetics, 49(1), 139-145. https://doi.org/10.1038/ng.3737
    • van Doorn, P., Rosing, J., Wielders, S. J., Hackeng, T. M., & Castoldi, E. (2017). The C-terminus of tissue factor pathway inhibitor-alpha inhibits factor V activation by protecting the Arg(1545) cleavage site. Journal of Thrombosis and Haemostasis, 15(1), 140-149. https://doi.org/10.1111/jth.13559
    • Houben, I. P. L., van Berlo, C. J. L. Y., Bekers, O., Nijssen, E. C., Lobbes, M. B. I., & Wildberger, J. E. (2017). Assessing the Risk of Contrast-Induced Nephropathy Using a Finger Stick Analysis in Recalls from Breast Screening: The CINFIBS Explorative Study. Contrast Media & Molecular Imaging, Article 5670384. https://doi.org/10.1155/2017/5670384
    • Severens-Rijvers, C. A. H., Al-Nasiry, S., Ghossein-Doha, C., Marzano, S., Ten Cate, H., Winkens, B., Spaanderman, M. A. E., & Peeters, L. L. H. (2017). Circulating Fibronectin and Plasminogen Activator Inhibitor-2 Levels as Possible Predictors of Recurrent Placental Syndrome: An Exploratory Study. Gynecologic and Obstetric Investigation, 82(4), 355-360. https://doi.org/10.1159/000449385
    • Koenen, R. (2017). Extrazelluläre Vesikel im Blut: Der verlängerte Arm der Blutplättchen. Trillium Diagnostik, 15(4), 256-258. https://www.trillium.de/zeitschriften/trillium-diagnostik/trillium-diagnostik-ausgaben-2017/td-42017/schwerpunkt/extrazellulaere-vesikel-der-verlaengerte-arm-der-blutplaettchen.html?L=0
    • Kuiper, G. J. A. J. M., Houben, R., Wetzels, R. J. H., Verhezen, P. W. M., van Oerle, R., ten Cate, H., Henskens, Y. M. C., & Lance, M. D. (2017). The use of regression analysis in determining reference intervals for low hematocrit and thrombocyte count in multiple electrode aggregometry and platelet function analyzer 100 testing of platelet function. Platelets, 28(7), 668-675. https://doi.org/10.1080/09537104.2016.1257782
    • Adler, M., Ivic, S., Bodmer, N. S., ten Cate, H., Bachmann, L. M., Wuillemin, W. A., & Nagler, M. (2017). Thromboelastometry and Thrombelastography Analysis under Normal Physiological Conditions - Systematic Review. Transfusion Medicine and Hemotherapy, 44(2), 78-83. https://doi.org/10.1159/000464297
    • Hendrikx, G., Hackeng, T. M., van Gorp, R., Bauwens, M., Schurgers, L. J., Mottaghy, F. M., Post, M. J., & Dijkgraaf, I. (2017). Use of Cyclic Backbone NGR-Based SPECT to Increase Efficacy of Postmyocardial Infarction Angiogenesis Imaging. Contrast Media & Molecular Imaging, 2017, Article 8638549. https://doi.org/10.1155/2017/8638549
    • Arts, M., Soons, Z., Dubois, L. J., Pierzchalski, K. A., Ellis, S. R., Balluff, B., Eijkel, G. B., Cramer, T., Lieuwes, N., Agten, S. M., Hackeng, T. M., Van Loon, L. J., Heeren, R. M., & Damink, S. W. O. (2017). Visualizing hepatocellular amino acid kinetics through mass spectrometry imaging of stable isotopes. Journal of Hepatology, 66(1), S43-S44. https://doi.org/10.1016/S0168-8278(17)30349-5
  • 2016
    • Magnette, A., Chatelain, M., Chatelain, B., Ten Cate, H., & Mullier, F. (2016). Pre-analytical issues in the haemostasis laboratory: guidance for the clinical laboratories. Thrombosis Journal, 14(1), Article 49. https://doi.org/10.1186/s12959-016-0123-z
    • Streng, A. S., de Boer, D., van Doorn, W. P. T. M., Kocken, J. M. M., Bekers, O., & Wodzig, W. K. W. H. (2016). Cardiac troponin T degradation in serum is catalysed by human thrombin. Biochemical and Biophysical Research Communications, 481(1-2), 165-168. https://doi.org/10.1016/j.bbrc.2016.10.149
    • Kuiper, G. J. A. J. M., & Henskens, Y. M. C. (2016). Rapid and Correct Prediction of Thrombocytopenia and Hypofibrinogenemia with Rotational Thromboelastometry in Cardiac Surgery Reconsidered. Journal of Cardiothoracic and Vascular Anesthesia, 30(6), 55-56. https://doi.org/10.1053/j.jvca.2016.04.009
    • Martens, R. J. H., Henry, R. M. A., Houben, A. J. H. M., van der Kallen, C. J. H., Kroon, A. A., Schalkwijk, C. G., Schram, M. T., Sep, S. J. S., Schaper, N. C., Dagnelie, P. C., Muris, D. M. J., Gronenschild, E. H. B. M., van der Sande, F. M., Leunissen, K. M. L., Kooman, J. P., & Stehouwer, C. D. A. (2016). Capillary Rarefaction Associates with Albuminuria: The Maastricht Study. Journal of the American Society of Nephrology, 27(12), 3748-3757. https://doi.org/10.1681/ASN.2015111219
    • Peeters, F. E. C. M., Van der Linden, N., Thomassen, A. L. L., Crijns, H. J. G. M., Meex, S. J. R., & Kietselaer, B. L. J. H. (2016). Clinical and echocardiographic determinants in bicuspid aortic dilatation Results from a longitudinal observational study. Medicine, 95(52), Article e5699. https://doi.org/10.1097/MD.0000000000005699
    • Klinkenberg, L. J. J., Wildi, K., van der Linden, N., Kouw, I. W. K., Niens, M., Twerenbold, R., Gimenez, M. R., Puelacher, C., Neuhaus, J. D., Hillinger, P., Nestelberger, T., Boeddinghaus, J., Grimm, K., Sabti, Z., Bons, J. A. P., van Suijlen, J. D. E., Tan, F. E. S., ten Kate, J., Bekers, O., ... Meex, S. J. R. (2016). Diurnal Rhythm of Cardiac Troponin: Consequences for the Diagnosis of Acute Myocardial Infarction. Clinical Chemistry, 62(12), 1602-1611. https://doi.org/10.1373/clinchem.2016.257485
    • ten Cate, V., ten Cate, H., & Verheugt, F. W. A. (2016). Erratum to: The Global Anticoagulant Registry in the FIELD - Atrial Fibrillation (GARFIELD-AF): Exploring the changes in anticoagulant practice in patients with non-valvular atrial fibrillation in the Netherlands (vol 24, pg 574, 2016). Netherlands Heart Journal, 24(12), 768-768. https://doi.org/10.1007/s12471-016-0916-5
    • Spauwen, P. J. J., Martens, R., Stehouwer, C. D. A., Verhey, F. R. J., Schram, M. T., Sep, S. J. S., van der Kallen, C. J. H., Dagnelie, P. C., Henry, R. M. A., Schaper, N. C., & van Boxtel, M. P. J. (2016). Lower verbal intelligence is associated with diabetic complications and slower walking speed in people with Type 2 diabetes: the Maastricht Study. Diabetic Medicine, 33(12), 1632–1639. https://doi.org/10.1111/dme.13105
    • Natarajan, P., Bis, J. C., Bielak, L. F., Cox, A. J., Dorr, M., Feitosa, M. F., Franceschini, N., Guo, X., Hwang, S.-J., Isaacs, A., Jhun, M. A., Kavousi, M., Li-Gao, R., Lyytikainen, L.-P., Marioni, R. E., Schminke, U., Stitziel, N. O., Tada, H., van Setten, J., ... O'Donnell, C. J. (2016). Multiethnic Exome-Wide Association Study of Subclinical Atherosclerosis. Circulation : Cardiovascular Genetics, 9(6), 511-520. https://doi.org/10.1161/CIRCGENETICS.116.001572
    • van der Linden, N., Klinkenberg, L. J. J., Bekers, O., van Loon, L. J. C., van Dieijen-Visser, M. P., Zeegers, M. P., & Meex, S. J. R. (2016). Prognostic value of basal high-sensitive cardiac troponin levels on mortality in the general population A meta-analysis. Medicine, 95(52), Article e5703. https://doi.org/10.1097/MD.0000000000005703
    • Ried, J. S., Jeff, J. M., Chu, A. Y., Bragg-Gresham, J. L., van Dongen, J., Huffman, J. E., Ahluwalia, T. S., Cadby, G., Eklund, N., Eriksson, J., Esko, T., Feitosa, M. F., Goel, A., Gorski, M., Hayward, C., Heard-Costa, N. L., Jackson, A. U., Jokinen, E., Kanoni, S., ... Roos, R. J. F. (2016). A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape. Nature Communications, 7. https://doi.org/10.1038/ncomms13357
    • Agten, S. M., Koenen, R. R., Ippel, H., Eckardt, V., von Hundelshausen, P., Mayo, K. H., Weber, C., & Hackeng, T. M. (2016). Probing Functional Heteromeric Chemokine Protein-Protein Interactions through Conformation-Assisted Oxime Ligation. Angewandte Chemie-International Edition, 55(48), 14963-14966. https://doi.org/10.1002/anie.201607036
    • Silva, C. T., Zorkoltseva, I. V., Amin, N., Demirkan, A., van Leeuwen, E. M., Kors, J. A., van den Berg, M., Stricker, B. H., Uitterlinden, A. G., Kirichenko, A. V., Witteman, J. C. M., Willemsen, R., Oostra, B. A., Axenovich, T. I., van Duijn, C. M., & Isaacs, A. (2016). A Combined Linkage and Exome Sequencing Analysis for Electrocardiogram Parameters in the Erasmus Rucphen Family Study. Frontiers in Genetics, 7(NOV), Article 190. https://doi.org/10.3389/fgene.2016.00190
    • Sörensen, B., Houben, B., Berendschot, T. T. J. M., Schouten, J. S. A. G., Kroon, A. A., van der Kallen, C. J. H., Henry, R. M. A., Koster, A., Sep, S. J. S., Dagnelie, P. C., Schaper, N. C., Schram, M. T., & Stehouwer, C. D. A. (2016). Prediabetes and Type 2 Diabetes Are Associated With Generalized Microvascular Dysfunction The Maastricht Study. Circulation, 134(18), 1339-1352. https://doi.org/10.1161/CIRCULATIONAHA.116.023446
    • Wentink, M. Q., Hackeng, T. M., Tabruyn, S. P., Puijk, W. C., Schwamborn, K., Altschuh, D., Meloen, R. H., Schuurman, T., Griffioen, A. W., & Timmerman, P. (2016). Targeted vaccination against the bevacizumab binding site on VEGF using 3D-structured peptides elicits efficient antitumor activity. Proceedings of the National Academy of Sciences of the United States of America, 113(44), 12532-12537. https://doi.org/10.1073/pnas.1610258113
    • Boersma, R. S., Hamulyak, K., van Oerle, R., Tuinenburg, A., Ten Cate - Hoek, A., & Schouten, H. C. (2016). Biomarkers for Prediction of Central Venous Catheter Related-Thrombosis in Patients With Hematological Malignancies. Clinical and Applied Thrombosis-Hemostasis, 22(8), 779-784. https://doi.org/10.1177/1076029615579098
    • Iotchkova, V., Huang, J., Morris, J. A., Jain, D., Barbieri, C., Walter, K., Min, J. L., Chen, L., Astle, W., Cocca, M., Deelen, P., Elding, H., Farmaki, A.-E., Franklin, C. S., Franberg, M., Gaunt, T. R., Hofman, A., Jiang, T., Kleber, M. E., ... Soranzo, N. (2016). Discovery and refinement of genetic loci associated with cardiometabolic risk using dense imputation maps. Nature Genetics, 48(11), 1303-1312. https://doi.org/10.1038/ng.3668
    • Zentai, C., Solomon, C., van der Meijden, P. E. J., Spronk, H. M. H., Schnabel, J., Rossaint, R., & Grottke, O. (2016). Effects of Fibrinogen Concentrate on Thrombin Generation, Thromboelastometry Parameters, and Laboratory Coagulation Testing in a 24-Hour Porcine Trauma Model. Clinical and Applied Thrombosis-Hemostasis, 22(8), 749-759. https://doi.org/10.1177/1076029615584662
    • Radu, C. M., Spiezia, L., Bulato, C., Gavasso, S., Campello, E., Sartorello, F., Castoldi, E., & Simioni, P. (2016). Endocytosis of exogenous factor V by ex-vivo differentiated megakaryocytes from patients with severe parahaemophilia. British Journal of Haematology, 175(3), 517-524. https://doi.org/10.1111/bjh.14262
    • de Waard, E. A. C., Koster, A., Melai, T., van Geel, T. A., Henry, R. M. A., Schram, M. T., Dagnelie, P. C., van der Kallen, C. J., Sep, S. J. S., Stehouwer, C. D. A., Schaper, N. C., Köhler, S., Savelberg, H. H. C. M., Geusens, P. P. M. M., & van den Bergh, J. P. W. (2016). The association between glucose metabolism status, diabetes severity and a history of fractures and recent falls in participants of 50 years and older-the Maastricht Study. Osteoporosis International, 27(11), 3207-3216. https://doi.org/10.1007/s00198-016-3645-0
    • Janssen, E. P. C. J., Köhler, S., Stehouwer, C. D. A., Schaper, N. C., Dagnelie, P. C., Sep, S. J. S., Henry, R. M. A., van der Kallen, C. J. H., Verhey, F. R., & Schram, M. T. (2016). The Patient Health Questionnaire-9 as a Screening Tool for Depression in Individuals with Type 2 Diabetes Mellitus: The Maastricht Study. Journal of the American Geriatrics Society, 64(11), E201-E206. https://doi.org/10.1111/jgs.14388
    • Haas, S., ten Cate, H., Accetta, G., Angchaisuksiri, P., Bassand, J.-P., Camm, A. J., Corbalan, R., Darius, H., Fitzmaurice, D. A., Goldhaber, S. Z., Goto, S., Jacobson, B., Kayani, G., Mantovani, L. G., Misselwitz, F., Pieper, K., Schellong, S. M., Stepinska, J., Turpie, A. G. G., ... Kakkar, A. K. (2016). Quality of Vitamin K Antagonist Control and 1-Year Outcomes in Patients with Atrial Fibrillation: A Global Perspective from the GARFIELD-AF Registry. PLOS ONE, 11(10), Article e0164076. https://doi.org/10.1371/journal.pone.0164076
    • van der Linden, N., Cornelis, T., Klinkenberg, L. J. J., Kimenai, D. M., Hilderink, J. M., Litjens, E. J. R., Kooman, J. P., Bekers, O., van Dieijen-Visser, M. P., & Meex, S. J. R. (2016). Strong diurnal rhythm of troponin T, but not troponin I, in a patient with renal dysfunction. International Journal of Cardiology, 221, 287-288. https://doi.org/10.1016/j.ijcard.2016.06.268
    • Marsch, E., Demandt, J. A. F., Theelen, T. L., Tullemans, B. M. E., Wouters, K., Boon, M. R., van Dijk, T. H., Gijbels, M. J., Dubois, L. J., Meex, S. J. R., Mazzone, M., Hung, G., Fisher, E. A., Biessen, E. A. L., Daemen, M. J. A. P., Rensen, P. C. N., Carmeliet, P., Groen, A. K., & Sluimer, J. C. (2016). Deficiency of the oxygen sensor prolyl hydroxylase 1 attenuates hypercholesterolaemia, atherosclerosis, and hyperglycaemia. European Heart Journal, 37(39), 2993-2997. https://doi.org/10.1093/eurheartj/ehw156
    • Bassand, J.-P., Accetta, G., Camm, A. J., Cools, F., Fitzmaurice, D. A., Fox, K. A. A., Goldhaber, S. Z., Goto, S., Haas, S., Hacke, W., Kayani, G., Mantovani, L. G., Misselwitz, F., ten Cate, H., Turpie, A. G. G., Verheugt, F. W. A., & Kakkar, A. K. (2016). Two-year outcomes of patients with newly diagnosed atrial fibrillation: results from GARFIELD-AF. European Heart Journal, 37(38), 2882-2889A. https://doi.org/10.1093/eurheartj/ehw233
    • Evans, D. S., Avery, C. L., Nalls, M. A., Li, G., Barnard, J., Smith, E. N., Tanaka, T., Butler, A. M., Buxbaum, S. G., Alonso, A., Arking, D. E., Berenson, G. S., Bis, J. C., Buyske, S., Carty, C. L., Chen, W., Chung, M. K., Cummings, S. R., Deo, R., ... Sotoodehnia, N. (2016). Fine-mapping, novel loci identification, and SNP association transferability in a genome-wide association study of QRS duration in African Americans. Human Molecular Genetics, 25(19), 4350-4368. https://doi.org/10.1093/hmg/ddw284
    • Geijselaers, S. L. C., Sep, S. J. S., Schram, M. T., van Boxtel, M. P. J., van Sloten, T. T., Henry, R. M. A., Reesink, K. D., Kroon, A. A., Koster, A., Schaper, N. C., Dagnelie, P. C., van der Kallen, C. J. H., Biessels, G. J., & Stehouwer, C. D. A. (2016). Carotid stiffness is associated with impairment of cognitive performance in individuals with and without type 2 diabetes. The Maastricht Study. Atherosclerosis, 253, 186-193. https://doi.org/10.1016/j.atherosclerosis.2016.07.912
    • Posma, J. J. N., Posthuma, J. J., & Spronk, H. M. H. (2016). Coagulation and non-coagulation effects of thrombin. Journal of Thrombosis and Haemostasis, 14(10), 1908-1916. https://doi.org/10.1111/jth.13441
    • Solari, F. A., Mattheij, N. J. A., Burkhart, J. M., Swieringa, F., Collins, P. W., Cosemans, J. M. E. M., Sickmann, A., Heemskerk, J. W. M., & Zahedi, R. P. (2016). Combined Quantification of the Global Proteome, Phosphoproteome, and Proteolytic Cleavage to Characterize Altered Platelet Functions in the Human Scott Syndrome. Molecular & Cellular Proteomics, 15(10), 3154-3169. https://doi.org/10.1074/mcp.M116.060368
    • Caolo, V., Vries, M., Zupancich, J., Houben, M., Mihov, G., Wagenaar, A., Swennen, G., Nossent, Y., Quax, P., Suylen, D., Dijkgraaf, I., Molin, D., Hackeng, T., & Post, M. (2016). CXCL1 microspheres: a novel tool to stimulate arteriogenesis. Drug Delivery, 23(8), 2919-2926. https://doi.org/10.3109/10717544.2015.1120366
    • van Erning, F. N., Zanders, M. M., Kuiper, J. G., van Herk-Sukel, M. P., Maas, H. A., Vingerhoets, R. W., Zimmerman, D. D., de Feyter, E. P., van de Poll, M. E., & Lemmens, V. E. (2016). Drug dispensings among elderly in the year before colon cancer diagnosis versus matched cancer-free controls. Journal of Clinical Pharmacy and Therapeutics, 41(5), 538-545. https://doi.org/10.1111/jcpt.12434
    • Amin, N., Allebrandt, K. V., van der Spek, A., Müller-Myhsok, B., Hek, K., Teder-Laving, M., Hayward, C., Esko, T., van Mill, J. G., Mbarek, H., Watson, N. F., Melville, S. A., Del Greco, F. M., Byrne, E. M., Oole, E., Kolcic, I., Chen, T.-H., Evans, D. S., Coresh, J., ... van Duijn, C. M. (2016). Genetic variants in RBFOX3 are associated with sleep latency. European Journal of Human Genetics, 24(10), 1488-1495. https://doi.org/10.1038/ejhg.2016.31