• 2010
    • Koenen, R. R., & Weber, C. (2010). Therapeutic targeting of chemokine interactions in atherosclerosis. Nature Reviews Drug Discovery, 9(2), 141-153. https://doi.org/10.1038/nrd3048
    • Duckers, C., Simioni, P., Spiezia, L., Radu, C. M., Dabrilli, P., Gavasso, S., Rosing, J., & Castoldi, E. (2010). Residual platelet factor V ensures thrombin generation in patients with severe congenital factor V deficiency and mild bleeding symptoms. Blood, 115(4), 879-886. https://doi.org/10.1182/blood-2009-08-237719
    • Wijnen, P. A. H. M., Bekers, O., & Drent, M. (2010). 'Drug'-induced pneumonitis associated with CYP and VKORC1 variants.The Bulletin of contemporary clinical medicine, 3, 15-17. https://doi.org/10.20969/VSKM.2010.3(4).15-17
    • Jacobs, L. H., van de Kerkhof, J. J., Mingels, A. M., Lima Passos, V., Kleijnen, V. W., Mazairac, A. H., van der Sande, F. M., Wodzig, W. K., Konings, C. J., Leunissen, K. M., van Dieijen-Visser, M. P., & Kooman, J. P. (2010). Inflammation, overhydration and cardiac biomarkers in haemodialysis patients: a longitudinal study.Nephrology Dialysis Transplantation, 25(1), 243-248. https://doi.org/10.1093/ndt/gfp417
    • Lobbes, M. B., Kooi, M. E., Lutgens, E., Lima Passos, V., Braat, S. H. J. G., Rousch, M. J. M., ten Cate, H., van Engelshoven, J. M., Daemen, M. J., & Heeneman, S. (2010). Leukocyte counts, myeloperoxidase, and pregnancy-associated plasma protein a as biomarkers for cardiovascular disease: towards a multi-biomarker approach.International Journal of Vascular Medicine, 2010(726207). https://doi.org/10.1155/2010/726207
    • Wijnen, P. A., Bekers, O., van Dieijen-Visser, M. P., & Drent, M. (2010). Pharmacogenetic testing after a simple DNA isolation method.The Bulletin of contemporary clinical medicine, 3, 9-14. https://doi.org/10.20969/VSKM.2010.3(4).9-14
    • Wisse, W., Rookhuizen, M. B., de Kruif, M. D., van Rossum, J., Jordans, I., ten Cate, H., van Loon, L. J. C., & Meesters, E. W. (2010). Prescription of physical activity is not sufficient to change sedentary behavior and improve glycemic control in type 2 diabetes patients.Diabetes Research and Clinical Practice, 88(2), E10-13. https://doi.org/10.1016/j.diabres.2010.01.015
    • Wijnen, P. A., Linssen, C. F., Haenen, G. R., Bekers, O., & Drent, M. (2010). Variant VKORC1 and CYP2C9 Alleles in Patients with Diffuse Alveolar Hemorrhage Caused by Oral Anticoagulants. Molecular Diagnosis & Therapy, 14(1), 23-30. https://doi.org/10.1007/BF03256350
    • Segers, O., van Oerle, R., ten Cate, H., Rosing, J., & Castoldi, E. (2010). Thrombin generation as an intermediate phenotype for venous thrombosis A proof-of-concept study. Thrombosis and Haemostasis, 103(1), 114-122. https://doi.org/10.1160/TH09-06-0356
    • Megens, R. T. A., Reitsma, S., Prinzen, L., Egbrink, M. G. A. O., Engels, W., Leenders, P. J. A., Brunenberg, E. J. L., Reesink, K. D., Janssen, B. J. A., Romeny, B. M. T. H., Slaaf, D. W., & van Zandvoort, M. A. M. J. (2010). In vivo high-resolution structural imaging of large arteries in small rodents using two-photon laser scanning microscopy. Journal of Biomedical Optics, 15(1), 10. Article 011108. https://doi.org/10.1117/1.3281672
    • Van de Vijver, P., Suylen, D. P., Dirksen, A., Dawson, P. E., & Hackeng, T. M. (2010). N-epsilon-(Thiaprolyl)-lysine as a Handle for Site-Specific Protein Conjugation. Biopolymers, 94(4), 465-474. https://doi.org/10.1002/bip.21485
    • Oostendorp, M., Douma, K., Hackeng, T. M., van Zandvoort, M. A. M. J., Post, M. J., & Backes, W. H. (2010). Pharmacokinetics of contrast agents targeted to the tumor vasculature in molecular magnetic resonance imaging. Contrast Media & Molecular Imaging, 5(1), 9-17. https://doi.org/10.1002/cmmi.361
    • Senen, K., Topal, E., Kilinc, E., ten Cate, H., Tek, I., Karakoc, Y., & Yetkin, E. (2010). Plasma viscosity and mean platelet volume in patients undergoing coronary angiography. Clinical Hemorheology and Microcirculation, 44(1), 35-41. https://doi.org/10.3233/CH-2010-1249
  • 2009
    • Klomp, C. M., ten Cate, H., Stehouwer, C. D., & Schaper, N. C. (2009). Acetylsalicylzuur bij patienten met diabetes mellitus: niet voor primaire, wel voor secundaire preventie van hart-vaatziekten. Nederlands Tijdschrift voor Geneeskunde, 153, A109. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=19785798
    • Wijnen, P. A., Limantoro, I., Drent, M., Bekers, O., Kuijpers, P. M., & Koek, G. H. (2009). Depressive effect of an antidepressant: therapeutic failure of venlafaxine in a case lacking CYP2D6 activity. Annals of Clinical Biochemistry, 46(Pt 6), 527-30. https://doi.org/10.1258/acb.2009.009003
    • Wolfs, J. L., Comfurius, P., Bekers, O., Zwaal, R. F., Balasubramanian, K., Schroit, A. J., Lindhout, T., & Bevers, E. M. (2009). Direct inhibition of phospholipid scrambling activity in erythrocytes by potassium ions. Cellular and Molecular Life Sciences, 66(2), 314-23. https://doi.org/10.1007/s00018-008-8566-4
    • Lind, J. S., Postmus, P. E., Heideman, D. A., Thunnissen, E. B., Bekers, O., & Smit, E. F. (2009). Dramatic response to low-dose erlotinib of epidermal growth factor receptor mutation-positive recurrent non-small cell lung cancer after severe cutaneous toxicity. Journal of Thoracic Oncology, 4(12), 1585-6. https://doi.org/10.1097/JTO.0b013e3181bbb2b9
    • Jacobs, L. H., van de Kerkhof, J., Mingels, A. M., Kleijnen, V. W., van der Sande, F. M., Wodzig, W. K., Kooman, J. P., & van Dieijen-Visser, M. P. (2009). Haemodialysis patients longitudinally assessed by highly sensitive cardiac troponin T and commercial cardiac troponin T and cardiac troponin I assays.Annals of Clinical Biochemistry, 46(Pt 4), 283-290. https://doi.org/10.1258/acb.2009.008197
    • Miserus, R. J., Herias, M. V., Prinzen, L., Lobbes, M. B., van Suylen, R. J., Dirksen, A., Hackeng, T. M., Heemskerk, J. W., van Engelshoven, J. M., Daemen, M. J. A. P., van Zandvoort, M. A. M. J., Heeneman, S., & Kooi, M. E. (2009). Molecular MRI of early thrombus formation using a bimodal alpha2-antiplasmin-based contrast agent. JACC-Cardiovascular Imaging, 2(8), 987-96. https://doi.org/10.1016/j.jcmg.2009.03.015
    • Wijnen, P. A. H. M., Drent, M., van Dieijen-Visser, M. P., & Bekers, O. (2009). Pharmacogenetic testing after a simple DNA isolation method on buccal swab samples. Pharmacogenomics, 10(6), 983-7. https://doi.org/10.2217/pgs.09.4
    • Miserus, R., Dirksen, A., Suylen, D. P., Herias, V., Prinzen, L., van Zandvoort, M. A. M. J., Kooi, M. E., Dawson, P., Heeneman, S., Daemen, M. J., & Hackeng, T. M. (2009). Total Chemical Synthesis of Bimodal-Labeled Rantes as a Pet/Tplsm Probe for in Vivo Molecular Imaging of Atherosclerotic Plaque Instability. Biopolymers, 92(4), 376-376. http://gateway.isiknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ResearchSoft&SrcApp=EndNote&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000266753100412
  • 2008
    • Vanschoonbeek, K., Wouters, K., van der Meijden, P. E., van Gorp, P. J. J., Feijge, M. A., Herfs, M., Schurgers, L. J., Hofker, M. H., de Maat, M. P., & Heemskerk, J. W. (2008). Anticoagulant effect of dietary fish oil in hyperlipidemia: a study of hepatic gene expression in APOE2 knock-in mice.Arteriosclerosis Thrombosis and Vascular Biology, 28(11), 2023-2029. https://doi.org/10.1161/ATVBAHA.107.156992
    • Linssen, C. F. M., Bekers, O., Drent, M., & Jacobs, J. A. (2008). C-reactive protein and procalcitonin concentrations in bronchoalveolar lavage fluid as a predictor of ventilator-associated pneumonia. Annals of Clinical Biochemistry, 45(Pt 3), 293-8. https://doi.org/10.1258/acb.2007.007133
    • van Schaik, R. H. N., Grandia, L., de Goede, A., Bet, P. M., Bekers, O., Guchelaar, H. J., Goldschmidt, H. M. J., Meijer, M. M. C., Mulder, H., van der Weide, J., & Deneer, V. H. M. (2008). CYP2D6 genotype `1-0' ingedeeld als intermediaire metaboliseerder.Nederlands tijdschrift voor klinische chemie en laboratoriumgeneeskunde, 33(1), 52.
    • Wijnen, P. A. H. M., op den Buijsch, R. A., Cheung, S. C., van der Heijden, J., Hoogtanders, K., Stolk, L. M. L., van Dieijen-Visser, M., Neef, C. K., Drent, M., & Bekers, O. (2008). Genotyping with a dried blood spot method: a useful technique for application in pharmacogenetics. Clinica Chimica Acta, 388(1-2), 189-91. https://doi.org/10.1016/j.cca.2007.10.001
    • Wijnen, P. A. H. M., Drent, M., Nelemans, P. J., Kuijpers, P. M., Koek, G. H., Neef, C. K., Haenen, G. R., & Bekers, O. (2008). Role of cytochrome p450 polymorphisms in the development of pulmonary drug toxicity: a case-control study in the Netherlands. Drug Safety, 31(12), 1125-34. https://doi.org/10.2165/0002018-200831120-00008
    • Ramakers, I. H. G. B., Visser, P. J., Aalten, P., Bekers, O., Sleegers, K., van Broeckhoven, C. L., Jolles, J., & Verhey, F. R. (2008). The association between APOE genotype and memory dysfunction in subjects with mild cognitive impairment is related to age and Alzheimer pathology. Dementia and Geriatric Cognitive Disorders, 26(2), 101-8. https://doi.org/10.1159/000144072
    • Cranenburg, E. C., Vermeer, C., Koos, R., Boumans, M. L., Hackeng, T. M., Bouwman, F. G., Kwaijtaal, M., Brandenburg, V. M., Ketteler, M., & Schurgers, L. J. (2008). The circulating inactive form of matrix Gla Protein (ucMGP) as a biomarker for cardiovascular calcification. Journal of Vascular Research, 45(5), 427-36. https://doi.org/10.1159/000124863
    • Meex, S. J., van Vliet-Ostaptchouk, J. V., van der Kallen, C. J. H., van Greevenbroek, M. M. J., Schalkwijk, C. G., Feskens, E. J. M., Blaak, E. E., Wijmenga, C., Hofker, M. H., Stehouwer, C. D., & de Bruin, T. W. (2008). Upstream transcription factor 1 (USF1) in risk of type 2 diabetes: Association study in 2000 Dutch Caucasians. Molecular Genetics and Metabolism, 94(3), 352-355. https://doi.org/10.1016/j.ymgme.2008.03.011
  • 2007
    • Meex, S. J., van Greevenbroek, M. M. J., Ayoubi, T. A., Vlietinck, R., van Vliet-Ostaptchouk, J. V., Hofker, M. H., Vermeulen, V. M., Schalkwijk, C. G., Feskens, E. J., Boer, J. M., Stehouwer, C. D., van der Kallen, C. J. H., & de Bruin, T. W. (2007). Activating transcription factor 6 polymorphisms and haplotypes are associated with impaired glucose homeostasis and type 2 diabetes in Dutch Caucasians. Journal of Clinical Endocrinology & Metabolism, 92(7), 2720-2725. https://doi.org/10.1210/jc.2006-2280
    • op den Buijsch, R. A., van de Plas, A., Stolk, L. M. L., Christiaans, M. H., van Hooff, J. P., Undre, N. A., van Dieijen-Visser, M. P., & Bekers, O. (2007). Evaluation of limited sampling strategies for tacrolimus. European Journal of Clinical Pharmacology, 63(11), 1039-1044. https://doi.org/10.1007/s00228-007-0354-9
    • Veltkamp, M., Wijnen, P. A. H. M., Moorsel, C. H., Rijkers, G. T., Ruven, H. J., Heron, M., Bekers, O., Claessen, A. M., Drent, M., Van den Bosch, J. M. M., & Grutters, J. C. (2007). Linkage between Toll-like receptor (TLR) 2 promotor and intron polymorphisms: functional effects and relevance to sarcoidosis.Clinical and Experimental Immunology, 149(3), 453-462. https://doi.org/10.1111/j.1365-2249.2007.03428.x
    • Wijnen, P. A. H. M., Op den Buisch, R., Drent, M., Kuipers, P. M. J. C., Neefs, C., Bast, A., Bekers, O., & Koek, G. H. (2007). Review article: The prevalence and clinical relevance of cytochrome P450 polymorphisms.Alimentary Pharmacology & Therapeutics, 26(2), 211-219. https://doi.org/10.1111/j.1365-2036.2007.03490.x
    • op den Buijsch, R. A., Christiaans, M. H., Stolk, L. M. L., de Vries, J. E., Cheung, C. Y., Undre, N. A., van Hooff, J. P., van Dieijen-Visser, M. P., & Bekers, O. (2007). Tacrolimus pharmacokinetics and pharmacogenetics: influence of adenosine triphosphate-binding cassette B1 (ABCB1) and cytochrome (CYP) 3A polymorphisms. Fundamental & Clinical Pharmacology, 21(4), 427-435. https://doi.org/10.1111/j.1472-8206.2007.00504.x
    • Llerena, A., Michel, G., Jeannesson, E., Wong, S., Manolopoulos, V. G., Hockett, R. D., Boubekeur, K., Siest, G., Beaune, P., Haefliger, C., Arnold, H. P., Junien, C., Petrovic, N., Molloy, R., Bekers, O., Donnelly, C., Arens, H. J., Kaput, J., & McComb, J. (2007). Third Santorini conference pharmacogenomics workshop report: "Pharmacogenomics at the crossroads: what else than good science will be needed for the field to become part of Personalized Medicine?". Clinical Chemistry and Laboratory Medicine, 45(7), 843-850. https://doi.org/10.1515/CCLM.2007.182
  • 2005
    • Fischer, M. A. J. G., Gransier, T. J., Beckers, L. M., Bekers, O., Bast, A., & Haenen, G. R. (2005). Determination of the antioxidant capacity in blood. Clinical Chemistry and Laboratory Medicine, 43(7), 735-740. https://doi.org/10.1515/CCLM.2005.125
    • op den Buijsch, R. A., de Vries, J. E., Loots, W. J., Landt, O., Wijnen, P. A. H. M., van Dieijen-Visser, M. P., & Bekers, O. (2005). Genotyping of the PXR A11156C polymorphism with locked nucleic acid containing fluorogenic probes. Pharmacogenomics, 5(2), 72-74. https://doi.org/10.1038/sj.tpj.6500299
    • Slofstra, S. H., van 't Veer, C., Buurman, W. A., Reitsma, P. H., ten Cate, H., & Spek, C. A. (2005). Low molecular weight heparin attenuates multiple organ failure in a murine model of disseminated intravascular coagulation. Critical Care Medicine, 33(6), 1365-1370. https://doi.org/10.1097/01.CCM.0000166370.94927.B6
    • van der Meijden, P. E. J., Feijge, M. A. H., Giesen, P. L. A., Huijberts, M. S. P., van Raak, L. P., & Heemskerk, J. W. (2005). Platelet P2Y12 receptors enhance signalling towards procoagulant activity and thrombin generation. A study with healthy subjects and patients at thrombotic risk. Thrombosis and Haemostasis, 93(6), 1128-1136. https://doi.org/10.1160/TH04-09-0597
    • Beerenhout, C. H., Luik, A. J., Jeuken Mertens, S. G., Bekers, O., Menheere, P. P., Hover, L., Klaassen, L., van der Sande, F. M., Cheriex, E. C., Meert, N., Leunissen, K. M. L., & Kooman, J. P. (2005). Pre-dilution on-line haemofiltration vs low-flux haemodialysis: a randomized prospective study. Nephrology Dialysis Transplantation, 20(6), 1155-1163. https://doi.org/10.1093/ndt/gfh775
    • op den Buijsch, R. A., Wijnen, P. A. H. M., van Dieijen-Visser, M. P., de Vries, J. E., & Bekers, O. (2005). Rapid genotyping of the OATP1B1 polymorphisms A388G and T521C with real-time PCR FRET assays. Pharmacogenomics, 6(4), 393-397. https://doi.org/10.1517/14622416.6.4.393
    • Meex, S. J. R., van der Kallen, C. J. H., van Greevenbroek, M. M., Eurlings, P. M., El Hasnaoui, M. M., Evelo, C. T., Lindsey, P. J., Luiken, J. J. F. P., Glatz, J. F., & de Bruin, T. W. (2005). Up-regulation of CD36/FAT in preadipocytes in familial combined hyperlipidemia. Faseb Journal, 19(14), 2063-2065. https://doi.org/10.1096/fj.04-2403fje
  • 2004
    • Keuren, J. F. W., Wielders, S. J. H., Driessen, A., Verhoeven, M., Hendriks, M., & Lindhout, T. (2004). Covalently-bound heparin makes collagen thromboresistant.Arteriosclerosis Thrombosis and Vascular Biology, 24(3), 613-617. https://doi.org/10.1161/01.ATV.0000116026.18945.66