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ZonMw grant Middellange termijn effecten van COVID-19 maatregelen

ZonMw grant Middellange termijn effecten van COVID-19 maatregelen

20 August 2024

The project 'Impact of COVID-19 protective measures and shielding in vulnerable patients with kidney failure', coordinated by Prof. Marc Hemmelder and Drs Pim Bouwmans (Dept of Internal Medicine), has been granted by ZonMw. 

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Professorship Henri Spronk

Professorship Henri Spronk

12 August 2024

Dr Henri Spronk (Dept of Biochemistry) has been appointed as professor of ‘Biochemistry of Atherothrombosis’ as of 1 May 2024.

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Carim Maastricht
Carim Maastricht

Wim van Zwam

Professor

Education/Training
• Medical study, MD (Free University, Amsterdam) 1989
• Tropical Medicine (Dutch Tropical Institute, Amsterdam) 1992
• Radiology (Maastricht University Medical Centre) 2002
• International Diplome in Neurovascular Diseases, MSc (Université Paris XI) 2004
 
Positions and Employment
• Resident Tropical Medicine (Surgery – Gynaecology) 1989 – 1992
Slotervaart General Hospital, Amsterdam
• Tropical Doctor, Medecins Sans Frontieres 1992 – 1994
Somalië, Laos, Sri Lanka
• Resident Radiology, MUMC+, Maastricht 1995 – 2002
• Interventional Radiology, Leuven, Belgium 2002
• Neuro-interventional Radiology, Tilburg 2002
• Neuro-interventional Radiology, Essen, Germany 2003
• Interventional Radiology, MUMC+, Maastricht 2003
 
Thesis, PhD: 2013
Aneurysmal subarachnoid hemorrhage: Imaging strategies and cost-effectiveness aspects in diagnostic work-up and post-therapeutic follow-up.
 
• PI of MACCA study (Magnetic resonance Angiography with Contrast in patients with Cerebra Aneurysms). Funding: 300k Euro from Profileringsfonds azM. 2006-2010 
• Co-PI, member of executive committee and imaging committee of the MRCLEAN trial (Multicenter Randomized Clinical trial of Endovascular treatment of Acute ischemic stroke in the Netherlands). 2010 - 2015
Funding: 800k Euro from Dutch Heart Foundaton; 500k Euro from unrestricted grants. 
 
Professional memberships: NVvR, NGIR, NNG, NVF, ESR, CIRSE, ESMINT, WFITN
Chair of Stroke Task Force, CIRSE
Board member of ESMINT
Member executive committee European Board of NeuroInterventions (EBNI)

PI of MRCLEAN_Late (MRCLEAN - patients arriving between 6 – 24 hrs after symptom onset), study under CONTRAST umbrella.
Co-PI, member of executive committee and imaging committee of CONTRAST (COnsortium for New Treatments in Acute Stroke).
Funding: 4000k Euro from Dutch Heart Foundaton; 4000k Euro from unrestricted grants. 200k Euro from Dutch Brain Council. 272k Euro from ZonMW
Member of executive committee MRCLEAN NoIV.
Wim-van-zwam

Department of Radiology and Nuclear Medicine
P. Debyelaan 25, 6229 HX Maastricht
PO Box 5800, 6202 AZ Maastricht
T: +31(0)43 387 69 09

  • 2016
    • Berkhemer, O. A., van den Berg, L. A., Fransen, P. S. S., Beumer, D., Yoo, A. J., Lingsma, H. F., Schonewille, W. J., van den Berg, R., Wermer, M. J. H., Boiten, J., Nijeholt, G. J. L., Nederkoorn, P. J., Hollmann, M. W., van Zwam, W. H., van der Lugt, A., van Oostenbrugge, R. J., Majoie, C. B. L. M., Dippel, D. W. J., & Roos, Y. B. W. E. M. (2016). The effect of anesthetic management during intra-arterial therapy for acute stroke in MR CLEAN. Neurology, 87(7), 656-664. https://doi.org/10.1212/WNL.0000000000002976
    • Mulder, M. J. H. L., Berkhemer, O. A., Fransen, P. S. S., Beumer, D., van den Berg, L. A., Lingsma, H. F., Roos, Y. B. W. E. M., van Oostenbrugge, R. J., van Zwam, W. H., Majoie, C. B. L. M., van der Lugt, A., & Dippel, D. W. J. (2016). Treatment in patients who are not eligible for intravenous alteplase: MR CLEAN subgroup analysis. International journal of stroke, 11(6), 637-645. https://doi.org/10.1177/1747493016641969
    • Yoo, A. J., Berkhemer, O. A., Fransen, P. S. S., van den Berg, L. A., Beumer, D., Lingsma, H. F., Schonewille, W. J., Sprengers, M. E. S., van den Berg, R., van Walderveen, M. A. A., Beenen, L. F. M., Wermer, M. J. H., Nijeholt, G. J. L. A., Boiten, J., Jenniskens, S. F. M., Bot, J. C. J., Boers, A. M. M., Marquering, H. A., Roos, Y. B. W. E. M., ... Majoie, C. B. L. M. (2016). Effect of baseline Alberta Stroke Program Early CT Score on safety and efficacy of intra-arterial treatment: a subgroup analysis of a randomised phase 3 trial (MR CLEAN). Lancet Neurology, 15(7), 685-694. https://doi.org/10.1016/S1474-4422(16)00124-1
    • Crijnen, Y. S., Nouwens, F., de Lau, L. M. L., Visch-Brink, E. G., van de Sandt-Koenderman, M. W. M. E., Berkhemer, O. A., Fransen, P. S. S., Beumer, D., van den Berg, L. A., Lingsma, H. F., Roos, Y. B. W. E. M., van der Lugt, A., van Oostenbrugge, R. J., van Zwam, W. H., Majoie, C. B. L. M., & Dippel, D. W. J. (2016). Early effect of intra-arterial treatment in ischemic stroke on aphasia recovery in MR CLEAN. Neurology, 86(22), 2049-2055. https://doi.org/10.1212/WNL.0000000000002724
    • Beumer, D., Rozeman, A. D., Nijeholt, G. J. L. A., Brouwer, P. A., Jenniskens, S. F. M., Algra, A., Boiten, J., Schonewille, W., van Oostenbrugge, R. J., Dippel, D. W. J., & van Zwam, W. H. (2016). The effect of age on outcome after intraarterial treatment in acute ischemic stroke: a MR CLEAN pretrial study. BMC Neurology, 16(1), Article 68. https://doi.org/10.1186/s12883-016-0592-5
    • Goyal, M., Menon, B. K., van Zwam, W. H., Dippel, D. W. J., Mitchell, P. J., Demchuk, A. M., Davalos, A., Majoie, C. B. L. M., van der Lugt, A., de Miquel, M. A., Donnan, G. R. A., Roos, Y. B. W. E. M., Bonafe, A., Jahan, R., Diener, H.-C., van den Berg, L. A., Levy, E. I., Berkhemer, O. A., Pereira, V. M., ... Jovin, T. G. (2016). Endovascular thrombectomy after large-vessel ischaemic stroke: a meta-analysis of individual patient data from five randomised trials. Lancet, 387(10029), 1723-1731. https://doi.org/10.1016/S0140-6736(16)00163-X
    • Berkhemer, O. A., Jansen, I. G. H., Beumer, D., Fransen, P. S. S., van den Berg, L. A., Yoo, A. J., Lingsma, H. F., Sprengers, M. E. S., Jenniskens, S. F. M., Lycklama a Nijeholt, G. J., van Walderveen, M. A. A., van den Berg, R., Bot, J. C. J., Beenen, L. F. M., Boers, A. M. M., Slump, C. H., Roos, Y. B. W. E. M., van Oostenbrugge, R. J., Dippel, D. W. J., ... Majoie, C. B. L. M. (2016). Collateral Status on Baseline Computed Tomographic Angiography and Intra-Arterial Treatment Effect in Patients With Proximal Anterior Circulation Stroke. Stroke, 47(3), 768-776. https://doi.org/10.1161/STROKEAHA.115.011788
    • Santos, E. M. M., Marquering, H. A., den Blanken, M. D., Berkhemer, O. A., Boers, A. M. M., Yoo, A. J., Beenen, L. F., Treurniet, K. M., Wismans, C., van Noort, K., Lingsma, H. F., Dippel, D. W. J., van der Lugt, A., van Zwam, W. H., Roos, Y. B. W. E. M., van Oostenbrugge, R. J., Niessen, W. J., & Majoie, C. B. (2016). Thrombus Permeability Is Associated With Improved Functional Outcome and Recanalization in Patients With Ischemic Stroke. Stroke, 47(3), 732-741. https://doi.org/10.1161/STROKEAHA.115.011187
    • MR CLEAN Investigators, van Zwam, W., & van Oostenbrugge, R. J. (2016). Observer variability of absolute and relative thrombus density measurements in patients with acute ischemic stroke. Neuroradiology, 58(2), 133-139. https://doi.org/10.1007/s00234-015-1607-4
    • Fransen, P. S. S., Berkhemer, O. A., Lingsma, H. F., Beumer, D., van den Berg, L. A., Yoo, A. J., Schonewille, W. J., Vos, J. A., Nederkoorn, P. J., Wermer, M. J. H., van Walderveen, M. A. A., Staals, J., Hofmeijer, J., van Oostayen, J. A., Nijeholt, G. J. L. A., Boiten, J., Brouwer, P. A., Emmer, B. J., de Bruijn, S. F., ... Dippel, D. W. J. (2016). Time to Reperfusion and Treatment Effect for Acute Ischemic Stroke A Randomized Clinical Trial. JAMA Neurology, 73(2), 190-196. https://doi.org/10.1001/jamaneurol.2015.3886
    • MR CLEAN Investigators, van Oostenbrugge, R. J., & van Zwam, W. (2016). Automated Entire Thrombus Density Measurements for Robust and Comprehensive Thrombus Characterization in Patients with Acute Ischemic Stroke. PLOS ONE, 11(1), Article e0145641. https://doi.org/10.1371/journal.pone.0145641
    • Wahlgren, N., Moreira, T., Michel, P., Steiner, T., Jansen, O., Cognard, C., Mattle, H. P., van Zwam, W., Holmin, S., Tatlisumak, T., Petersson, J., Caso, V., Hacke, W., Mazighi, M., Arnold, M., Fischer, U., Szikora, I., Pierot, L., Fiehler, J., ... Lees, K. R. (2016). Mechanical thrombectomy in acute ischemic stroke: Consensus statement by ESO-Karolinska Stroke Update 2014/2015, supported by ESO, ESMINT, ESNR and EAN. International journal of stroke, 11(1), 134-147. https://doi.org/10.1177/1747493015609778
    • de Ridder, I. R., Fransen, P. S. S., Beumer, D., Berkhemer, O. A., van den Berg, L. A., Wermer, M. J., Lingsma, H., van Zwam, W. H., Roos, Y. B., van Oostenbrugge, R. J., Majoie, C. B., van der Lugt, A., & Dippel, D. W. J. (2016). Is Intra-Arterial Treatment for Acute Ischemic Stroke Less Effective in Women than in Men?Interventional Neurology, 5(3-4), 174-178. https://doi.org/10.1159/000447331
    • Beumer, D., Mulder, M. J. H. L., Saiedie, G., Fonville, S., van Oostenbrugge, R. J., van Zwam, W., Homburg, P. J., van der Lugt, A., & Dippel, D. W. J. (2016). Occurence of intracranial large vessel occlusion in consecutive, non-referred patients with acute ischemic stroke. Neurovascular Imaging, 2, Article 11. https://doi.org/10.1186/s40809-016-0022-5
  • 2015
    • Sailer, A. M., van Zwam, W. H., Wildberger, J. E., & Grutters, J. P. C. (2015). Cost-effectiveness modelling in diagnostic imaging: a stepwise approach. European Radiology, 25(12), 3629-3637. https://doi.org/10.1007/s00330-015-3770-8
    • Broderick, J. P., Berkhemer, O. A., Palesch, Y. Y., Dippel, D. W. J., Foster, L. D., Roos, Y. B. W. E. M., van der Lugt, A., Tomsick, T. A., Majoie, C. B. L. M., van Zwam, W. H., Demchuk, A. M., van Oostenbrugge, R. J., Khatri, P., Lingsma, H. F., Hill, M. D., Roozenbeek, B., Jauch, E. C., Jovin, T. G., Yan, B., ... Simpson, K. N. (2015). Endovascular Therapy Is Effective and Safe for Patients With Severe Ischemic Stroke. Stroke, 46(12), 3416-3422. https://doi.org/10.1161/STROKEAHA.115.011397
    • Borst, J., Berkhemer, O. A., Roos, Y. B. W. E. M., van Bavel, E., van Zwam, W. H., van Oostenbrugge, R. J., van Walderveen, M. A. A., Lingsma, H. F., van der Lugt, A., Dippel, D. W. J., Yoo, A. J., Marquering, H. A., & Majoie, C. B. L. M. (2015). Value of Computed Tomographic Perfusion-Based Patient Selection for Intra-Arterial Acute Ischemic Stroke Treatment. Stroke, 46(12), 3375-3382. https://doi.org/10.1161/STROKEAHA.115.010564
    • Geuskens, R. R. E. G., Borst, J., Lucas, M., Boers, A. M. M., Berkhemer, O. A., Roos, Y. B. W. E. M., van Walderveen, M. A. A., Jenniskens, S. F. M., van Zwam, W. H., Dippel, D. W. J., Majoie, C. B. L. M., & Marquering, H. A. (2015). Characteristics of Misclassified CT Perfusion Ischemic Core in Patients with Acute Ischemic Stroke. PLOS ONE, 10(11), Article e0141571. https://doi.org/10.1371/journal.pone.0141571
    • Berkhemer, O. A., van Zwam, W. H., & Dippel, D. W. J. (2015). Stent-Retriever Thrombectomy for Stroke. New England Journal of Medicine, 373(11), 1076-1076. https://doi.org/10.1056/NEJMc1508744
    • Sailer, A. M., Schurink, G. W. H., Bol, M. E., de Haan, M. W., van Zwam, W. H., Wildberger, J. E., & Jeukens, C. R. L. P. N. (2015). Occupational Radiation Exposure During Endovascular Aortic Repair. Cardiovascular and Interventional Radiology, 38(4), 827-832. https://doi.org/10.1007/s00270-014-1025-8
    • van den Berg, L. A., Koelman, D. L. H., Berkhemer, O. A., Rozeman, A. D., Fransen, P. S. S., Beumer, D., Dippel, D. W., van der Lugt, A., van Oostenbrugge, R. J., van Zwam, W. H., Brouwer, P. A., Jenniskens, S., Boiten, J., Nijeholt, G. A. L. A., Vos, J. A., Schonewille, W. J., Majoie, C. B. L. M., & Roos, Y. B. W. E. M. (2015). Type of Anesthesia and Differences in Clinical Outcome After Intra-Arterial Treatment for Ischemic Stroke. Stroke, 46(5), 1257-1262. https://doi.org/10.1161/STROKEAHA.115.008699
    • Sailer, A. M., de Haan, M. W., de Graaf, R., van Zwam, W. H., Schurink, G. W. H., Nelemans, P. J., Wildberger, J. E., & Das, M. (2015). Fusion Guidance in Endovascular Peripheral Artery Interventions: A Feasibility Study. Cardiovascular and Interventional Radiology, 38(2), 314-321. https://doi.org/10.1007/s00270-014-0951-9
    • Sailer, A. M., Schurink, G. W. H., Wildberger, J. E., de Graaf, R., van Zwam, W. H., de Haan, M. W., Kemerink, G. J., & Jeukens, C. R. L. P. N. (2015). Radiation Exposure of Abdominal Cone Beam Computed Tomography. Cardiovascular and Interventional Radiology, 38(1), 112-120. https://doi.org/10.1007/s00270-014-0900-7
    • Berkhemer, O. A., Fransen, P. S. S., Beumer, D., van den Berg, L. A., Lingsma, H. F., Yoo, A. J., Schonewille, W. J., Vos, J. A., Nederkoorn, P. J., Wermer, M. J. H., van Walderveen, M. A. A., Staals, J., Hofmeijer, J., van Oostayen, J. A., Nijeholt, G. J. L. A., Boiten, J., Brouwer, P. A., Emmer, B. J., de Bruijn, S. F., ... Dippel, D. W. J. (2015). A Randomized Trial of Intraarterial Treatment for Acute Ischemic Stroke. New England Journal of Medicine, 372(1), 11-20. https://doi.org/10.1056/NEJMoa1411587
  • 2014
    • van Rooijen, B. D., de Haan, M. W., Das, M., Arnoldussen, C. W. K. P., de Graaf, R., van Zwam, W. H., Backes, W. H., & Jeukens, C. R. L. P. N. (2014). Efficacy of Radiation Safety Glasses in Interventional Radiology. Cardiovascular and Interventional Radiology, 37(5), 1149-1155. https://doi.org/10.1007/s00270-013-0766-0
    • Fransen, P. S. S., Beumer, D., Berkhemer, O. A., van den Berg, L. A., Lingsma, H., van der Lugt, A., van Zwam, W. H., van Oostenbrugge, R. J., Roos, Y. B. W. E. M., Majoie, C. B., & Dippel, D. W. J. (2014). MR CLEAN, a multicenter randomized clinical trial of endovascular treatment for acute ischemic stroke in the Netherlands: study protocol for a randomized controlled trial. Trials, 15(1), Article 343. https://doi.org/10.1186/1745-6215-15-343
    • Santos, E. M. M., Marquering, H. A., Berkhemer, O. A., van Zwam, W. H., van der Lugt, A., Majoie, C. B., & Niessen, W. J. (2014). Development and Validation of Intracranial Thrombus Segmentation on CT Angiography in Patients with Acute Ischemic Stroke. PLOS ONE, 9(7), Article e101985. https://doi.org/10.1371/journal.pone.0101985
    • Tijssen, M. P. M., Hofman, P. A. M., Stadler, A. A. R., van Zwam, W., de Graaf, R., van Oostenbrugge, R. J., Klotz, E., Wildberger, J. E., & Postma, A. A. (2014). The role of dual energy CT in differentiating between brain haemorrhage and contrast medium after mechanical revascularisation in acute ischaemic stroke. European Radiology, 24(4), 834-840. https://doi.org/10.1007/s00330-013-3073-x
    • Sailer, A. M. H., Wagemans, B. A. J. M., Nelemans, P. J., de Graaf, R., & van Zwam, W. H. (2014). Diagnosing Intracranial Aneurysms With MR Angiography: Systematic Review and Meta-Analysis. Stroke, 45(1), 119-126. https://doi.org/10.1161/STROKEAHA.113.003133
  • 2011
    • Ferns, S. P., Sprengers, M. E. S., van Rooij, W. J., van Zwam, W. H., de Kort, G. A. P., Velthuis, B. K., Schaafsma, J. D., van den Berg, R., Sluzewski, M., Brouwer, P. A., Rinkel, G. J. E., & Majoie, C. B. L. M. (2011). Late Reopening of Adequately Coiled Intracranial Aneurysms Frequency and Risk Factors in 400 Patients With 440 Aneurysms. Stroke, 42(5), 1331-1337. https://doi.org/10.1161/STROKEAHA.110.605790
    • Klompenhouwer, E. G., Dings, J. T. A., van Oostenbrugge, R. J., Oei, S., Wilmink, J. T., & van Zwam, W. H. (2011). Single-Center Experience of Surgical and Endovascular Treatment of Ruptured Intracranial Aneurysms. American Journal of Neuroradiology, 32(3), 570-575. https://doi.org/10.3174/ajnr.A2326
    • Ferns, S. P., Sprengers, M. E. S., van Rooij, W. J., van den Berg, R., Velthuis, B. K., de Kort, G. A. P., Sluzewski, M., van Zwam, W. H., Rinkel, G. J. E., & Majoie, C. B. L. M. (2011). De Novo Aneurysm Formation and Growth of Untreated Aneurysms A 5-Year MRA Follow-Up in a Large Cohort of Patients With Coiled Aneurysms and Review of the Literature. Stroke, 42(2), 313-318. https://doi.org/10.1161/STROKEAHA.110.591594
  • 2004
    • Moonen, H. J., Dommels, Y. E., van Zwam, W. H., van Herwijnen, M. H. M., Kleinjans, J. C., Alink, G. M., & de Kok, T. M. (2004). Effects of polyunsaturated fatty acids on prostaglandin synthesis and cyclooxygenase-mediated DNA adduct formation by heterocyclic aromatic amines in human adenocarcinoma colon cells. Molecular Carcinogenesis, 40(3), 180-188. https://doi.org/10.1002/mc.20032
  • 2000
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