Wim van Zwam

Professor

Education/Training
• Medical study, MD (Free University, Amsterdam) 1989
• Tropical Medicine (Dutch Tropical Institute, Amsterdam) 1992
• Radiology (Maastricht University Medical Centre) 2002
• International Diplome in Neurovascular Diseases, MSc (Université Paris XI) 2004
 
Positions and Employment
• Resident Tropical Medicine (Surgery – Gynaecology) 1989 – 1992
Slotervaart General Hospital, Amsterdam
• Tropical Doctor, Medecins Sans Frontieres 1992 – 1994
Somalië, Laos, Sri Lanka
• Resident Radiology, MUMC+, Maastricht 1995 – 2002
• Interventional Radiology, Leuven, Belgium 2002
• Neuro-interventional Radiology, Tilburg 2002
• Neuro-interventional Radiology, Essen, Germany 2003
• Interventional Radiology, MUMC+, Maastricht 2003
 
Thesis, PhD: 2013
Aneurysmal subarachnoid hemorrhage: Imaging strategies and cost-effectiveness aspects in diagnostic work-up and post-therapeutic follow-up.
 
• PI of MACCA study (Magnetic resonance Angiography with Contrast in patients with Cerebra Aneurysms). Funding: 300k Euro from Profileringsfonds azM. 2006-2010 
• Co-PI, member of executive committee and imaging committee of the MRCLEAN trial (Multicenter Randomized Clinical trial of Endovascular treatment of Acute ischemic stroke in the Netherlands). 2010 - 2015
Funding: 800k Euro from Dutch Heart Foundaton; 500k Euro from unrestricted grants. 
 
Professional memberships: NVvR, NGIR, NNG, NVF, ESR, CIRSE, ESMINT, WFITN
Chair of Stroke Task Force, CIRSE
Board member of ESMINT
Member executive committee European Board of NeuroInterventions (EBNI)

PI of MRCLEAN_Late (MRCLEAN - patients arriving between 6 – 24 hrs after symptom onset), study under CONTRAST umbrella.
Co-PI, member of executive committee and imaging committee of CONTRAST (COnsortium for New Treatments in Acute Stroke).
Funding: 4000k Euro from Dutch Heart Foundaton; 4000k Euro from unrestricted grants. 200k Euro from Dutch Brain Council. 272k Euro from ZonMW
Member of executive committee MRCLEAN NoIV.

Department of Radiology and Nuclear Medicine
P. Debyelaan 25, 6229 HX Maastricht
PO Box 5800, 6202 AZ Maastricht
T: +31(0)43 387 69 09

  • 2023
    • Rinkel, L. A., Treurniet, K. M., Kappelhof, M., LeCouffe, N. E., Bruggeman, A. A. E., Nieboer, D., van Zwam, W. H., Uyttenboogaart, M., Dippel, D. W. J., Emmer, B. J., Roos, Y. B. W. E. M., Majoie, C. B. L. M., Coutinho, J. M., & MR CLEAN-NO IV Investigators (2023). Influence of time metrics on the treatment effect of intravenous alteplase prior to endovascular treatment in MR CLEAN-NO IV. Journal of Neurointerventional Surgery, 15(E1), e54-e59. https://doi.org/10.1136/jnis-2022-018998
    • Knapen, R. R. M. M., Bernsen, M. L. E., Langezaal, L. C. M., Olthuis, S. G. H., Michel, P., Hofmeijer, J., Vos, J.-A., van Kuijk, S. M. J., Majoie, C. B., Emmer, B. J., Nijeholt, G. J. L. A., Boiten, J., Puetz, V., Gerber, J., Mazighi, M., Pontes-Neto, O. M., Mont'Alverne, F., Yoo, A. J., van Doormaal, P.-J., ... Schonewille, W. J. (2023). Aspiration Versus Stent Retriever Thrombectomy in Basilar-Artery Occlusion; Results From the BASICS Trial. Stroke: vascular and interventional neurology, 3(4), Article e000768. https://doi.org/10.1161/SVIN.122.000768
    • Terreros, N. A., Renon, S., Zucchelli, F., Bridio, S., Matas, J. F. R., Dubini, G., Konduri, P. R., Koopman, M. S., Zwam, W. H. V., Yo, L. S. F., Lo, R. H., Marquering, H. A., van Bavel, E., Majoie, C. B. L. M., Migliavacca, F., & Luraghi, G. (2023). Microcatheter tracking in thrombectomy procedures: A finite-element simulation study. Computer Methods and Programs in Biomedicine, 234(1), Article 107515. https://doi.org/10.1016/j.cmpb.2023.107515
    • van den Berg, L. A., Berkhemer, O., Fransen, P. S. S., Beumer, D., Majoie, C. B. L., Dippel, D. W. J., van der Lugt, A. J., van Oostenbrugge, R. H., van Zwam, W. B., Roos, Y., Dijkgraaf, M. G. W., & MR CLEAN Investigators (2023). Budget impact of endovascular treatment for acute ischaemic stroke patients in the Netherlands for 2015-2021. Netherlands Heart Journal, 31(6), 254-259. https://doi.org/10.1007/s12471-023-01788-x
    • Pinckaers, F. M., Mentink, M. M., Boogaarts, H. D., van Zwam, W. H., van Oostenbrugge, R. J., & Postma, A. A. (2023). Early post-endovascular treatment contrast extravasation on dual-energy CT is associated with clinical and radiological stroke outcomes: A 10-year single-centre experience. European Stroke Journal, 8(2), 508-516. https://doi.org/10.1177/23969873231157901
    • Collette, S. A., van de Ven, E., Luijckx, G.-J. R. F., Lingsma, H., van Doormaal, P. J., van Es, A. C. G. M. R., van den Wijngaard, I., Goldhoorn, R.-J. B., de Groot, J. C. H., van Zwam, W., Majoie, C. B. L. M., Dippel, D. W. J., Bokkers, R. P. H., Uyttenboogaart, M., & MR CLEAN Registry Investigators (2023). Alternative Arterial Access Routes for Endovascular Thrombectomy in Patients with Acute Ischemic Stroke: A Study from the MR CLEAN Registry. Journal of Clinical Medicine, 12(9), Article 3257. https://doi.org/10.3390/jcm12093257
    • Benali, F., Kappelhof, M., Ospel, J., Ganesh, A., McDonough, R. V., Postma, A. A., Goldhoorn, R.-J. B., Majoie, C. B. L. M., van den Wijngaard, I., Lingsma, H. F., Vos, J. A., van Oostenbrugge, R. J., van Zwam, W. H., Goyal, M., & MR CLEAN Registry Investigators (2023). Benefit of successful reperfusion achieved by endovascular thrombectomy for patients with ischemic stroke and moderate pre-stroke disability (mRS 3): results from the MR CLEAN Registry. Journal of Neurointerventional Surgery, 15(5), 433-438. https://doi.org/10.1136/neurintsurg-2022-018853
    • Olthuis, S. G. H., Pirson, F. A. V., Pinckaers, F. M. E., Hinsenveld, W. H., Nieboer, D., Ceulemans, A., Knapen, R. R. M. M., Robbe, M. M. Q., Berkhemer, O. A., van Walderveen, M. A. A., Lycklama À Nijeholt, G. J., Uyttenboogaart, M., Schonewille, W. J., van der Sluijs, P. M., Wolff, L., van Voorst, H., Postma, A. A., Roosendaal, S. D., van der Hoorn, A., ... MR CLEAN-LATE Investigators (2023). Endovascular treatment versus no endovascular treatment after 6-24 h in patients with ischaemic stroke and collateral flow on CT angiography (MR CLEAN-LATE) in the Netherlands: a multicentre, open-label, blinded-endpoint, randomised, controlled, phase 3 trial. Lancet, 401(10385), 1371-1380. https://doi.org/10.1016/S0140-6736(23)00575-5
    • Amini, M., Eijkenaar, F., Lingsma, H. F. F., den Hartog, S. J. J., Olthuis, S. G. H., Martens, J., van der Worp, B., van Zwam, W., van der Hoorn, A., Roosendaal, S. D. D., Roozenbeek, B., Dippel, D., van Leeuwen, N., & MR CLEAN Registry Investigators (2023). Validity of Early Outcomes as Indicators for Comparing Hospitals on Quality of Stroke Care. Journal of the American Heart Association, 12(8), Article e027647. https://doi.org/10.1161/JAHA.122.027647
    • Brouwer, J., Ergezen, S., Mulder, M. J. H. L., Nijeholt, G. J. L. A., Van Es, A. C. G. M., Van Der Lugt, A., Dippel, D. W. J., Majoie, C. B. L. M., Roos, Y. B. W. E. M., Coutinho, J. M., Emmer, B. J., Van Oostenbrugge, R. J., Van Zwam, W. H., Boiten, J., Vos, J. A., Jansen, I. G. H., Goldhoorn, R. J. B., Compagne, K. C. J., Kappelhof, M., ... MR CLEAN Registry Investigators (2023). Endovascular treatment for isolated posterior cerebral artery occlusion stroke in the MR CLEAN registry. Journal of Neurointerventional Surgery, 15(4), 363-369. https://doi.org/10.1136/neurintsurg-2021-018505
    • van Voorst, H., Bruggeman, A. A. E., Andriessen, J. W., Hoving, J. R., Konduri, P., Yang, W., Kappelhof, M., Terreros, N. A., Roos, Y. B. W. E. M. H., van Zwam, W., van der Lugt, A., van der Hoorn, A., Boiten, J., Roosendaal, S., Jenniskens, S., Caan, M. W. A. A., Marquering, H. J., Emmer, B., & Majoie, C. B. L. M. (2023). Prognostic Value of Thrombus Volume and Interaction With First-Line Endovascular Treatment Device Choice. Stroke, 54(4), 1056-1065. https://doi.org/10.1161/STROKEAHA.122.041606
    • Terreros, N. A., Bruggeman, A. A. E., van Voorst, H., Konduri, P. R., Jansen, I. G. H., Kappelhof, M., Tolhuisen, M. L., Boodt, N., Dippel, D. W. J., van der Lugt, A., van Zwam, W. H., van Oostenbrugge, R. J., van der Worp, H. B., Emmer, B. J., Meijer, F. J. A., Roos, Y. B. W. E. M., van Bavel, E., Marquering, H. A., & Majoie, C. B. L. M. (2023). Bifurcation occlusions and endovascular treatment outcome in acute ischemic stroke. Journal of Neurointerventional Surgery, 15(4), 355-362. https://doi.org/10.1136/neurintsurg-2021-018560
    • Dhillon, P. S., White, P., Goyal, M., van Zwam, W. H., & Lenthall, R. (2023). Perfusion imaging in acute ischaemic stroke-the beginning of the end?Clinical Medicine, 23(2), 185-187. https://doi.org/10.7861/clinmed.2022-0554
    • Olthuis, S. G. H., Hinsenveld, W. H., Pinckaers, F. M. E., Amini, M., Lingsma, H. F., Staals, J., Schreuder, T. H. C. M. L., Schonewille, W. J., Yo, L. S. F., Roos, Y. B. W. E. M., Postma, A. A., Dippel, D. W. J., van Zwam, W. H., van Oostenbrugge, R. J., de Ridder, I. R., & MR CLEAN Registry Investigators (2023). Association between type of intervention center and outcomes after endovascular treatment for acute ischemic stroke: Results from the MR CLEAN Registry. European Stroke Journal, 8(1), 224-230. https://doi.org/10.1177/23969873221145771
    • Flint, A. C., Chan, S. L., Edwards, N. J., Rao, V. A., Klingman, J. G., Nguyen-Huynh, M. N., Yan, B., Mitchell, P. J., Davis, S. M., Campbell, B. C., Dippel, D. W., Roos, Y. B., Van Zwam, W. H., Saver, J. L., Kidwell, C. S., Hill, M. D., Goyal, M., Demchuk, A. M., Bracard, S., ... On Behalf Of The Vista-Endovascular Collaboration (2023). Outcome prediction in large vessel occlusion ischemic stroke with or without endovascular stroke treatment: THRIVE-EVT. International journal of stroke, 18(3), 331-337. Article 17474930221092262. https://doi.org/10.1177/17474930221092262
    • Bourcier, R., Goyal, M., Muir, K. W., Desal, H., Dippel, D. W. J., Majoie, C. B. L. M., van Zwam, W. H., Jovin, T. G., Mitchell, P. J., Demchuk, A. M., van Oostenbrugge, R. J., Brown, S. B., Campbell, B., White, P., Hill, M. D., Saver, J. L., Weimar, C., Jahan, R., Guillemin, F., ... HERMES Trialists Collaboration (2023). Risk factors of unexplained early neurological deterioration after treatment for ischemic stroke due to large vessel occlusion: a post hoc analysis of the HERMES study. Journal of Neurointerventional Surgery, 15(3), 221-226. https://doi.org/10.1136/neurintsurg-2021-018214
    • Sluis, W. M., Hinsenveld, W. H., Goldhoorn, R. J. B., Potters, L. H., Bruggeman, A. A. E., van der Hoorn, A., Bot, J. C. J., van Oostenbrugge, R. J., Lingsma, H. F., Hofmeijer, J., van Zwam, W. H., Majoie, C. B., van der Worp, H. B., & MR CLEAN Registry Investigators (2023). Timing and causes of death after endovascular thrombectomy in patients with acute ischemic stroke. European Stroke Journal, 8(1), 215-223. https://doi.org/10.1177/23969873221143210
    • Su, J., Li, S., Wolff, L., van Zwam, W., Niessen, W. J., van der Lugt, A., & van Walsum, T. (2023). Deep reinforcement learning for cerebral anterior vessel tree extraction from 3D CTA images. Medical Image Analysis, 84(1), Article 102724. https://doi.org/10.1016/j.media.2022.102724
    • Bock, L. A., Noben, C. Y., van Mook, W. N., de Ridder, I. R., van Zwam, W. H., Schenck, H. E., Haeren, R. H., & Essers, B. A. (2023). Endovascular treatment and neurosurgical clipping in subarachnoid hemorrhage: a systematic review of economic evaluations. Journal of Neurosurgical Sciences, 67(1), 18-25. https://doi.org/10.23736/S0390-5616.21.05503-X
    • Samuels, N., Compagne, K. C. J., van der Ende, N. A. M., Chalos, V., Konduri, P. R., van Doormaal, P. J., van Zwam, W. H., Majoie, C. B. L. M., Marquering, H. A., Roozenbeek, B., Lingsma, H. F., Dippel, D. W. J., van der Lugt, A., & MR CLEAN Investigators (2023). Infarct volume after ischemic stroke as a mediator of the effect of endovascular thrombectomy on early postprocedural neurologic deficit. Journal of Stroke & Cerebrovascular Diseases, 32(2), Article 106906. https://doi.org/10.1016/j.jstrokecerebrovasdis.2022.106906
    • Olthuis, S. G. H., den Hartog, S. J., van Kuijk, S. M. J., Staals, J., Benali, F., van der Leij, C., Beumer, D., Nijeholt, G. J. L. A., Uyttenboogaart, M., Martens, J. M., Van Doormaal, P. J., Vos, J. A., Emmer, B. J., Dippel, D. W. J., van Zwam, W. H., van Oostenbrugge, R. J., de Ridder, I. R., & MR CLEAN Registry Investigators (2023). Influence of the interventionist's experience on outcomes of endovascular thrombectomy in acute ischemic stroke: results from the MR CLEAN Registry. Journal of Neurointerventional Surgery, 15(2), 113-119. https://doi.org/10.1136/neurintsurg-2021-018295
    • de Vries, J., Aquarius, R., Sørensen, L., Boogaarts, H. D., Turowski, B., van Zwam, W. H., Marotta, T. R., & Bartels, R. H. M. A. (2023). Safety and efficacy of the eCLIPs bifurcation remodelling system for the treatment of wide necked bifurcation aneurysms: 1 year results from the European eCLIPs Safety, Feasibility, and Efficacy Study (EESIS). Journal of Neurointerventional Surgery, 15(2), 163-171. https://doi.org/10.1136/neurintsurg-2021-018460
    • Bruggeman, A. A. E., Kappelhof, M., den Hartog, S. J., Burke, J. F., Berkhemer, O. A., van Es, A. C. G. M., van Zwam, W. H., Dippel, D. W. J., Coutinho, J. M., Marquering, H. A., Majoie, C. B. L. M., Emmer, B. J., & MR CLEAN Registry Investigators (2023). Successful reperfusion in relation to the number of passes: comparing outcomes of first pass expanded Treatment In Cerebral Ischemia (eTICI) 2B with multiple-pass eTICI 3. Journal of Neurointerventional Surgery, 15(2), 120-126. https://doi.org/10.1136/neurintsurg-2021-018465
    • Su, J., Wolff, L., van Doormaal, P. J., Dippel, D. W. J., van Zwam, W., Niessen, W. J., van der Lugt, A., & van Walsum, T. (2023). Time dependency of automated collateral scores in computed tomography angiography and computed tomography perfusion images in patients with intracranial arterial occlusion. Neuroradiology, 65(2), 313-322. https://doi.org/10.1007/s00234-022-03050-4
    • Boodt, N., Bruggeman, A. A. E., Kappelhof, M., den Hartog, S. J., Terreros, N. A., Martens, J. M., Bokkers, R. P. H., van Doormaal, P.-J., Majoie, C. B. L. M., van Zwam, W. H., Marquering, H. A., Dippel, D. W. J., van der Lugt, A., Lingsma, H. F., & MR CLEAN Registry Investigators (2023). Value of Thrombus Imaging Characteristics as a Guide for First-Line Endovascular Thrombectomy Device in Patients With Acute Ischemic Stroke. Stroke: vascular and interventional neurology, 3(1), Article e000450. https://doi.org/10.1161/SVIN.122.000450
    • Ospel, J. M., Kunz, W. G., McDonough, R. V., van Zwam, W., Pinckaers, F., Saver, J. L., Hill, M. D., Demchuk, A. M., Jovin, T. G., Mitchell, P., Campbell, B. C. V., White, P., Muir, K., Achit, H., Bracard, S., Brown, S., Goyal, M., & HERMES Investigators (2023). Cost-Effectiveness of Endovascular Treatment in Large Vessel Occlusion Stroke With Mild Prestroke Disability: Results From the HERMES Collaboration. Stroke, 54(1), 226-233. https://doi.org/10.1161/STROKEAHA.121.038407
    • van Kranendonk, K. R., Kappelhof, M., Bruggeman, A. A. E., Rinkel, L. A., Treurniet, K. M., LeCouffe, N., Emmer, B. J., Coutinho, J. M., Wolff, L., van Zwam, W. H., van Oostenbrugge, R. J., van der Lugt, A., Dippel, D. W. J., Roos, Y. B. W. E. M., Marquering, H. A., Majoie, C. B. L. M., & MR CLEAN-NO IV Investigators (2023). Hemorrhage rates in patients with acute ischemic stroke treated with intravenous alteplase and thrombectomy versus thrombectomy alone. Journal of Neurointerventional Surgery, 15(E2), E262-E269. https://doi.org/10.1136/jnis-2022-019569
    • Arrarte Terreros, N., Bruggeman, A. A., Kappelhof, M., Tolhuisen, M. L., Brouwer, J., Hoving, J. W., Konduri, P. R., van Kranendonk, K. R., Dutra, B. G., Alves, H. C., Dippel, D. W., van Zwam, W. H., Beenen, L. F., Yo, L. S., van Bavel, E., Majoie, C. B., Marquering, H. A., & MR CLEAN Registry Investigators (2023). Thrombus imaging characteristics within acute ischemic stroke: similarities and interdependence. Journal of Neurointerventional Surgery, 15(e1), e60-e68. https://doi.org/10.1136/jnis-2022-019134
  • 2022
    • Gerbasi, A., Konduri, P., Tolhuisen, M., Cavalcante, F., Rinkel, L., Kappelhof, M., Wolff, L., Coutinho, J. M., Emmer, B. J., Costalat, V., Arquizan, C., Hofmeijer, J., Uyttenboogaart, M., van Zwam, W., Roos, Y., Quaglini, S., Bellazzi, R., Majoie, C., Marquering, H., & MR CLEAN-NO IV Investigators (2022). Prognostic Value of Combined Radiomic Features from Follow-Up DWI and T2-FLAIR in Acute Ischemic Stroke. Journal of Cardiovascular Development and Disease, 9(12), Article 468. https://doi.org/10.3390/jcdd9120468
    • Prasetya, H., Tolhuisen, M. L., Koopman, M. S., Kappelhof, M., Meijer, F. J. A., Yo, L. S. F., Á Nijeholt, G. J. L., van Zwam, W. H., van der Lugt, A., Roos, Y. B. W. E. M., Majoie, C. B. L. M., van Bavel, E. T., Marquering, H. A., & On Behalf Of The Mr Clean Registry Investigators (2022). Value of CT Perfusion for Collateral Status Assessment in Patients with Acute Ischemic Stroke. Diagnostics, 12(12), Article 3014. https://doi.org/10.3390/diagnostics12123014
    • Wolff, L., Su, J., Van Loon, D., van Es, A., van Doormaal, P. J., Majoie, C., van Zwam, W., Dippel, D., van der Lugt, A., van Walsum, T., & MR CLEAN Investigators (2022). Inter-rater reliability for assessing intracranial collaterals in patients with acute ischemic stroke: comparing 29 raters and an artificial intelligence-based software. Neuroradiology, 64(12), 2277-2284. https://doi.org/10.1007/s00234-022-02984-z
    • van der Steen, W., van der Ende, N. A. M., van Kranendonk, K. R., Chalos, V., Brouwer, J., van Oostenbrugge, R. J., van Zwam, W. H., van Doormaal, P. J., van Es, A. C. G. M., Majoie, C. B. L. M., van der Lugt, A., Dippel, D. W. J., Roozenbeek, B., MR CLEAN Trial, & MR CLEAN Registry Investigators (2022). Timing of symptomatic intracranial hemorrhage after endovascular stroke treatment. European Stroke Journal, 7(4), 393-401. https://doi.org/10.1177/23969873221112279
    • Rinkel, L. A., Treurniet, K. M., Nieboer, D., Kappelhof, M., LeCouffe, N. E., Bruggeman, A. A. E., van Zwam, W. H., Lycklama À Nijeholt, G. J., Ghariq, E., Uyttenboogaart, M., Dippel, D. W. J., Roos, Y. B. W. E. M., Coutinho, J. M., Majoie, C. B. L. M., Emmer, B. J., & MR CLEAN-NO IV Investigators (2022). Effect of Intravenous Alteplase Treatment on First-Line Stent Retriever Versus Aspiration Alone During Endovascular Treatment. Stroke, 53, 3278-3288. https://doi.org/10.1161/strokeaha.121.038390
    • Konduri, P., Bucker, A., Boers, A., Dutra, B., Samuels, N., Treurniet, K., Berkhemer, O., Yoo, A., van Zwam, W., van Oostenbrugge, R., van der Lugt, A., Dippel, D., Roos, Y., Bot, J., Majoie, C., Marquering, H., & MR CLEAN Trial Investigators (2022). Risk factors of late lesion growth after acute ischemic stroke treatment. Frontiers in Neurology, 13, Article 977608. https://doi.org/10.3389/fneur.2022.977608
    • Luijten, S. P. R., Compagne, K. C. J., van Es, A. C. G. M., Roos, Y. B. W. E. M., Majoie, C. B. L. M., van Oostenbrugge, R. J., van Zwam, W. H., Dippel, D. W. J., Wolters, F. J., van der Lugt, A., Bos, D., & MR CLEAN Trial Investigators (2022). Brain atrophy and endovascular treatment effect in acute ischemic stroke: a secondary analysis of the MR CLEAN trial. International journal of stroke, 17(8), 881-888. Article 17474930211054964. https://doi.org/10.1177/17474930211054964
    • van der Steen, W., van der Sluijs, P. M., van de Graaf, R. A., Su, R., Wolff, L., van Voorst, H., den Hertog, H. M., van Doormaal, P. J., van Es, A. C. G. M., Staals, J., van Zwam, W., Lingsma, H. F., van den Berg, R., Majoie, C. B. L. M., van der Lugt, A., Dippel, D. W. J., Roozenbeek, B., & MR CLEAN-MED investigators (2022). Safety and efficacy of periprocedural antithrombotics in patients with successful reperfusion after endovascular stroke treatment. Journal of Stroke & Cerebrovascular Diseases, 31(10), Article 106726. https://doi.org/10.1016/j.jstrokecerebrovasdis.2022.106726
    • Kersten, C. J. B. A., Zandbergen, A. A. M., Berkhemer, O. A., Borst, J., Haalboom, M., Roos, Y. B. W. E. M., Dippel, D. W. J., van Oostenbrugge, R. J., van der Lugt, A., van Zwam, W. H., Majoie, C. B., den Hertog, H. M., & MR CLEAN Investigators (2022). Association of hyperglycemia and computed tomographic perfusion deficits in patients who underwent endovascular treatment for acute ischemic stroke caused by a proximal intracranial occlusion: A subgroup analysis of a randomized phase 3 trial (MR CLEAN). Journal of the Neurological Sciences, 440, Article 120333. https://doi.org/10.1016/j.jns.2022.120333
    • Bruggeman, A. A. E., Aberson, N., Kappelhof, M., Dutra, B. G., Hoving, J. W., Brouwer, J., Tolhuisen, M. L., Terreros, N. A., Konduri, P. R., Boodt, N., Roos, Y. B. W. E. M., van Zwam, W. H., Bokkers, R., Martens, J., Marquering, H. A., Emmer, B. J., Majoie, C. B. L. M., & MR CLEAN Registry Investigators (2022). Association of thrombus density and endovascular treatment outcomes in patients with acute ischemic stroke due to M1 occlusions. Neuroradiology, 64(9), 1857-1867. https://doi.org/10.1007/s00234-022-02971-4
    • van der Steen, W., van der Ende, N. A. M., van Kranendonk, K. R., Chalos, V., van Oostenbrugge, R. J., van Zwam, W. H., Roos, Y. B. W. E. M., van Doormaal, P. J., van Es, A. C. G. M., Lingsma, H. F., Majoie, C. B. L. M., van der Lugt, A., Dippel, D. W. J., Roozenbeek, B., & MR CLEAN Trial and MR CLEAN Registry Investigators (2022). Determinants of Symptomatic Intracranial Hemorrhage After Endovascular Stroke Treatment: A Retrospective Cohort Study. Stroke, 53(9), 2818-2827. https://doi.org/10.1161/STROKEAHA.121.036195
    • Wolff, L., Uniken Venema, S. M., Luijten, S. P. R., Hofmeijer, J., Martens, J. M., Bernsen, M. L. E., van Es, A. C. G. M., van Doormaal, P. J., Dippel, D. W. J., van Zwam, W., van Walsum, T., van der Lugt, A., & MR CLEAN Registry Investigators (2022). Diagnostic performance of an algorithm for automated collateral scoring on computed tomography angiography. European Radiology, 32(8), 5711-5718. https://doi.org/10.1007/s00330-022-08627-4
    • Luijten, S. P. R., Wolff, L., Duvekot, M. H. C., van Doormaal, P. J., Moudrous, W., Kerkhoff, H., Nijeholt, G. J., Bokkers, R. P. H., Yo, L. S. F., Hofmeijer, J., van Zwam, W. H., van Es, A. C. G. M., Dippel, D. W. J., Roozenbeek, B., van der Lugt, A., & MR CLEAN Registry and PRESTO investigators (2022). Diagnostic performance of an algorithm for automated large vessel occlusion detection on CT angiography. Journal of Neurointerventional Surgery, 14(8), 794-798. https://doi.org/10.1136/neurintsurg-2021-017842
    • Pirson, F. A. V. A., Boodt, N., Brouwer, J., Bruggeman, A. A. E., Hinsenveld, W. H., Staals, J., van Zwam, W. H., van der Leij, C., Brans, R. J. B., Majoie, C. B. L. M., Dippel, D. W. J., van der Lugt, A., Schonewille, W. J., van Oostenbrugge, R. J., & MR CLEAN Registry Investigators (2022). Etiology of Large Vessel Occlusion Posterior Circulation Stroke: Results of the MR CLEAN Registry. Stroke, 53(8), 2468-2477. https://doi.org/10.1161/strokeaha.121.038054
    • van Voorst, H., Konduri, P. R., van Poppel, L. M., van der Steen, W., van der Sluijs, P. M., Slot, E. M. H., Emmer, B. J., van Zwam, W. H., Roos, Y. B. W. E. M., Majoie, C. B. L. M., Zaharchuk, G., Caan, M. W. A., Marquering, H. A., & CONTRAST Consortium Collaborators (2022). Unsupervised Deep Learning for Stroke Lesion Segmentation on Follow-up CT Based on Generative Adversarial Networks. American Journal of Neuroradiology, 43(8), 1107-1114. https://doi.org/10.3174/ajnr.A7582
    • van Voorst, H., Bruggeman, A. A. E., Yang, W. J., Andriessen, J., Welberg, E., Dutra, B. G., Konduri, P. R., Terreros, N. A., Hoving, J. W., Tolhuisen, M. L., Kappelhof, M., Brouwer, J., Boodt, N., van Kranendonk, K. R., Koopman, M. S., Hund, H. M., Krietemeijer, M., van Zwam, W. H., van Beusekom, H. M. M., ... MR CLEAN Registry Investigators (2022). Thrombus radiomics in patients with anterior circulation acute ischemic stroke undergoing endovascular treatment. Journal of Neurointerventional Surgery. https://doi.org/10.1136/jnis-2022-019085
    • Tolhuisen, M. L., Hoving, J. W., Koopman, M. S., Kappelhof, M., van Voorst, H., Bruggeman, A. E., Demchuck, A. M., Dippel, D. W. J., Emmer, B. J., Bracard, S., Guillemin, F., van Oostenbrugge, R. J., Mitchell, P. J., van Zwam, W. H., Hill, M. D., Roos, Y. B. W. E. M., Jovin, T. G., Berkhemer, O. A., Campbell, B. C. V., ... HERMES Investigators (2022). Outcome Prediction Based on Automatically Extracted Infarct Core Image Features in Patients with Acute Ischemic Stroke. Diagnostics, 12(8), Article 1786. https://doi.org/10.3390/diagnostics12081786
    • van de Graaf, R. A., Samuels, N., Chalos, V., Nijeholt, G. J. L. A., van Beusekom, H., Yoo, A. J., van Zwam, W. H., Majoie, C. B. L. M., Roos, Y. B. W. E. M., van Doormaal, P. J., Ben Hassen, W., van der Lugt, A., Dippel, D. W. J., Lingsma, H. F., van Es, A. C. G. M., Roozenbeek, B., & MR CLEAN Registry Investigators (2022). Predictors of poor outcome despite successful endovascular treatment for ischemic stroke: results from the MR CLEAN Registry. Journal of Neurointerventional Surgery, 14(7), 660-665. https://doi.org/10.1136/neurintsurg-2021-017726
    • Zoetmulder, R., Bruggeman, A. A. E., Isgum, I., Gavves, E., Majoie, C. B. L. M., Beenen, L. F. M., Dippel, D. W. J., Boodt, N., den Hartog, S. J., van Doormaal, P. J., Cornelissen, S. A. P., Roos, Y. B. W. E. M., Brouwer, J., Schonewille, W. J., Pirson, A. F. V., van Zwam, W. H., van der Leij, C., Brans, R. J. B., van Es, A. C. G. M., ... MR CLEAN Registry Investigators (2022). Deep-Learning-Based Thrombus Localization and Segmentation in Patients with Posterior Circulation Stroke. Diagnostics, 12(6), Article 1400. https://doi.org/10.3390/diagnostics12061400
    • Koopman, M. S., Hoving, J. W., van Voorst, H., Daems, J. D., Peerlings, D., Buskens, E., Lingsma, H. F., Marquering, H. A., de Jong, H. W. A. M., Berkhemer, O. A., van Zwam, W. H., van Walderveen, M. A. A., van den Wijngaard, I., van der Lugt, A., Dippel, D. W. J., Yoo, A. J., Campbell, B. C. V., Kunz, W. G., Majoie, C. B. L. M., ... CLEOPATRA Investigators (2022). Cost-effectiveness of CT perfusion for patients with acute ischemic stroke (CLEOPATRA)-Study protocol for a healthcare evaluation study. European Stroke Journal, 7(2), 188-197. Article 23969873221092535. https://doi.org/10.1177/23969873221092535
    • Compagne, K. C. J., Kappelhof, M., Hinsenveld, W. H., Brouwer, J., Goldhoorn, R.-J. B., Uyttenboogaart, M., Bokkers, R. P. H., Schonewille, W. J., Martens, J. M., Hofmeijer, J., van der Worp, H. B., Lo, R. T. H., Keizer, K., Yo, L. S. F., Lycklama À Nijeholt, G. J., den Hertog, H. M., Sturm, E. J. C., Brouwers, P. J. A. M., van Walderveen, M. A. A., ... MR CLEAN Registry Investigators (2022). Improvements in Endovascular Treatment for Acute Ischemic Stroke: A Longitudinal Study in the MR CLEAN Registry. Stroke, 53(6), 1863-1872. https://doi.org/10.1161/STROKEAHA.121.034919