PI group Leon Schurgers
- 2025
- Hoitz, N. C. C., Nugteren, M. J., Huizing, E., Fioole, B., Mees, B. M. E., de Borst, G. J., & Ünlü, Ç. (2025). Duplex ultrasound surveillance after femoropopliteal endovascular treatment for peripheral arterial disease: a systematic review and narrative synthesis. Annals of Vascular Surgery, 110, 145-158. Advance online publication. https://doi.org/10.1016/j.avsg.2024.05.035
- 2024
- Sangani, N. B., Koetsier, J., Gomes, A. R., Diogo, M. M., Fernandes, T. G., Bouwman, F. G., Mariman, E. C. M., Ghazvini, M., Gribnau, J., Curfs, L. M. G., Reutelingsperger, C. P., & Eijssen, L. M. T. (2024). Involvement of extracellular vesicle microRNA clusters in developing healthy and Rett syndrome brain organoids. Cellular and Molecular Life Sciences, 81(1), Article 410. https://doi.org/10.1007/s00018-024-05409-7
- Amiral, J., Ferol, R., Busch, M. H., Timmermans, S. A. M. E. G., Reutelingsperger, C., & van Paassen, P. (2024). Laboratory measurement of autoantibodies to Annexin A1: Review and measurements in health and COVID-19. Transfusion and Apheresis Science, 63(6), Article 104027. https://doi.org/10.1016/j.transci.2024.104027
- Tobal, R., Potjewijd, J., de Vries, F., van Doorn, D. P. C., Jaminon, A., Bittner, R., Akbulut, C., van Empel, V., Heeringa, P., Damoiseaux, J., Schurgers, L., & van Paassen, P. (2024). Dephosphorylated uncarboxylated Matrix-Gla-Protein as candidate biomarker for immune-mediated vascular remodeling and prognosis in pulmonary hypertension. Scientific Reports, 14(1), Article 26633. https://doi.org/10.1038/s41598-024-77000-w
- Medina, I., Wieland, E. B., Temmerman, L., Otten, J. J. T., Bermudez, B., Bot, I., Rademakers, T., Wijnands, E., Schurgers, L., Mees, B., van Berkel, T. J. C., Goossens, P., & Biessen, E. A. L. (2024). Colony stimulating factor 1 receptor (Csf1r) expressing cell ablation in mafia (macrophage-specific Fas-induced apoptosis) mice alters monocyte landscape and atherosclerotic lesion characteristics. European Journal of Immunology, 54(11), Article 2350943. https://doi.org/10.1002/eji.202350943
- Zomer, B., Ruiter, M. S., Dekker, F. W., Goertz, E. G. D., de Haan, M. W., Hemmelder, M. H. H., Hiligsmann, M. J. C., Konijn, W. S., van Loon, M. M., Maessen, J. M. C., Mees, B. M. E., Rotmans, J. I., Schurink, G. W. H., Vleugels, M. J. JPJ., & Snoeijs, M. G. J. (2024). FLOW: Flow dysfunction of hemodialysis vascular access: A randomized controlled trial on the effectiveness of surveillance of arteriovenous fistulas and grafts. Journal of vascular access, 25(6), 2007-2017. https://doi.org/10.1177/11297298231212754
- Wegner, M., Smeets, R. R., Veenstra, L. F., Ahmad, W., Behrens, A. L., Kursch, F., Wienemann, H., Dorweiler, B., Baldus, S., Adam, M., Mees, B. M. E., & Meertens, M. M. (2024). Comparison of patients with occlusive or hemorrhagic access site complications requiring reintervention after percutaneous transfemoral transcatheter aortic valve implantation. Vasa-European Journal of Vascular Medicine. Advance online publication. https://doi.org/10.1024/0301-1526/a001154
- Frankort, J., Doukas, P., Uhl, C., Otte, N., Krabbe, J., Mees, B., Jacobs, M. J., & Gombert, A. (2024). Determinants of Neurological Outcome Following Elective and Emergency Open Thoracoabdominal Aortic Aneurysm Repair-A Retrospective Multi-Center Study. Journal of Clinical Medicine, 13(18), Article 5473. https://doi.org/10.3390/jcm13185473
- Berard, M., Chassain, K., Mery, C., Gillaizeau, F., Carton, T., Humeau, H., Navasiolava, N., Rocour, S., Schurgers, L., Kempf, M., & Martin, L. (2024). Changes in the gut microbiota of pseudoxanthoma elasticum patients. Annales de Dermatologie et de Venereologie, 151(3), Article 103290. https://doi.org/10.1016/j.annder.2024.103290
- van Vliet, L. V., Zonnebeld, N., Tordoir, J. H., Huberts, W., Bouwman, L. H., Cuypers, P. W., Heinen, S. G., Huisman, L. C., Lemson, S., Mees, B. M. E., Schlosser, F. J., de Smet, A. A., Toorop, R. J., Delhaas, T., & Snoeijs, M. G. (2024). Guideline recommendations on minimal blood vessel diameters and arteriovenous fistula outcomes. Journal of vascular access, 25(5), 1584-1592. https://doi.org/10.1177/11297298231180627
- van Vliet, L. V., Delhaas, T., Mees, B. M. E., & Snoeijs, M. G. (2024). Response letter. Journal of vascular access, 25(5), 1705-1707. https://doi.org/10.1177/11297298231218663
- Tinelli, G., D'Oria, M., Sica, S., Mani, K., Rancic, Z., Resh, T. A., Beccia, F., Azizzadeh, A., Da Volta Ferreira, M. M., Gargiulo, M., Lepidi, S., Tshomba, Y., Oderich, G. S., Haulon, S., SLIM F-U EVAR Collaborative Study Group, & Mees, B. (2024). The sac evolution imaging follow-up after endovascular aortic repair: an international expert opinion-based Delphi consensus study. Journal of Vascular Surgery, 80(3), 937-945. https://doi.org/10.1016/j.jvs.2024.03.007
- Vink, C. E. M., de Jong, E. A. M., Woudstra, J., Molenaar, M., Kamp, O., Götte, M. J. W., van Raalte, D. H., Serné, E., van de Hoef, T. P., Chamuleau, S. A. J., Eringa, E. C., & Appelman, Y. (2024). The role of myocardial blood volume in the pathophysiology of angina with non-obstructed coronary arteries: The MICORDIS study. International Journal of Cardiology, 415, Article 132479. https://doi.org/10.1016/j.ijcard.2024.132479
- Rademakers, T., Manca, M., Jin, H., Orban, T., Perisic, L. M., Frissen, H. J. M., Rühle, F., Hautvast, P., van Rijssel, J., van Kuijk, K., Mees, B. M. E., Peutz-Kootstra, C. J., Heeneman, S., Daemen, M. J. A. P., Pasterkamp, G., Stoll, M., van Zandvoort, M. A. M. J., Hedin, U., Dequiedt, F., ... Biessen, E. A. L. (2024). Human atherosclerotic plaque transcriptomics reveals endothelial beta-2 spectrin as a potential regulator a leaky plaque microvasculature phenotype. Angiogenesis, 27(3), 461-474. https://doi.org/10.1007/s10456-024-09921-z
- Lemmens, C. C., Konings, T. J. A. J., Dean, A., Wanhainen, A., Mani, K., Gormley, S., Khashram, M., Mees, B. M. E., & Schurink, G. W. H. (2024). Branch Thrombus after Endovascular Treatment with Arch Branched Devices for Aortic Arch Pathologies. European Journal of Vascular and Endovascular Surgery. Advance online publication. https://doi.org/10.1016/j.ejvs.2024.07.023
- Kane, J., Vos, W. G., Bosmans, L. A., van Os, B. W., den Toom, M., Hoeksema-Hackmann, S., Moen-de Wit, D., Gijbels, M. J., Beckers, L., Grefhorst, A., Levels, J. H. M., Jakulj, L., Vervloet, M. G., Lutgens, E., & Eringa, E. C. (2024). Peritoneal Dialysis Aggravates and Accelerates Atherosclerosis in Uremic ApoE-/- Mice. Journal of the American Heart Association, 13(14), e034066. Article e034066. https://doi.org/10.1161/JAHA.123.034066
- Smorenburg, S. P. M., Lely, R. J., Jacobs, M. J., & Hoksbergen, A. W. J. (2024). Aortic aneurysm sac filling with AneuFix injectable polymer during endovascular aneurysm repair: feasibility and safety trial study protocol. BMJ Open, 14(7), Article e082380. https://doi.org/10.1136/bmjopen-2023-082380
- Jin, H., Zhang, C., Nagenborg, J., Juhasz, P., Ruder, A. V., Sikkink, C. J. J. M., Mees, B. M. E., Waring, O., Sluimer, J. C., Neumann, D., Goossens, P., Donners, M. M. P. C., Mardinoglu, A., & Biessen, E. A. L. (2024). Genome-scale metabolic network of human carotid plaque reveals the pivotal role of glutamine/glutamate metabolism in macrophage modulating plaque inflammation and vulnerability. Cardiovascular Diabetology, 23(1), Article 240. https://doi.org/10.1186/s12933-024-02339-3
- Hatzl, J., van Basten Batenburg, M., Yeung, K. K., Fioole, B., Verhoeven, E., Lauwers, G., Kölbel, T., Wever, J. J., Scheinert, D., Van den Eynde, W., Rouhani, G., Mees, B. M. E., Vermassen, F., Schelzig, H., Böckler, D., Cuypers, P. W. M., & Zephyr study group collaborators (2024). Clinical Performance of the Low Profile Zenith Alpha Abdominal Endovascular Graft: 2 Year Results from the ZEPHYR Registry. European Journal of Vascular and Endovascular Surgery, 68(1), 40-48. https://doi.org/10.1016/j.ejvs.2024.03.004
- Broering, M. F., Tocci, S., Sout, N. T., Reutelingsperger, C., Farsky, S. H. P., Das, S., & Sayed, I. M. (2024). Development of an Inflamed High Throughput Stem-cell-based Gut Epithelium Model to Assess the Impact of Annexin A1. Stem Cell Reviews and Reports, 20(5), 1299-1310. https://doi.org/10.1007/s12015-024-10708-4
- Bahram Sangani, N., Koetsier, J., Mélius, J., Kutmon, M., Ehrhart, F., Evelo, C. T., Curfs, L. M. G., Reutelingsperger, C. P., & Eijssen, L. M. T. (2024). A novel insight into neurological disorders through HDAC6 protein-protein interactions. Scientific Reports, 14(1), Article 14666. https://doi.org/10.1038/s41598-024-65094-1
- Bastos Gonçalves, F., Mees, B., Tulamo, R., & members of the ESVS Guidelines Steering Committee (2024). ESVS Guidelines App: Bringing Evidence Based Vascular Practice to your Pocket. European Journal of Vascular and Endovascular Surgery, 67(6), 872-874. https://doi.org/10.1016/j.ejvs.2024.03.008
- Ünlü, Ç., Deloose, K., & Mees, B. (2024). Guidewire Selection and Techniques in Peripheral Arterial Interventions. European Journal of Vascular and Endovascular Surgery, 67(6), 1027-1030. https://doi.org/10.1016/j.ejvs.2024.01.015
- Konings, T. J. A. J., Delhaas, T., & Mees, B. M. E. (2024). Re: "Thoracic Stent Graft Numerical Models to Virtually Simulate Thoracic Endovascular Aortic Repair. European Journal of Vascular and Endovascular Surgery, 67(6), 1025. https://doi.org/10.1016/j.ejvs.2024.02.024
- Hoitz, N., Kraima, A., Fioole, B., Mees, B., de Borst, G. J., & Ünlü, Ç. (2024). Surveillance After Surgical and Endovascular Treatment for Peripheral Artery Disease: a Dutch Survey. European Journal of Vascular and Endovascular Surgery, 67(6), 980-986. https://doi.org/10.1016/j.ejvs.2023.12.029
- Ganizada, B. H., J. A. Veltrop, R., Akbulut, A. C., Koenen, R. R., Accord, R., Lorusso, R., Maessen, J. G., Reesink, K., Bidar, E., & Schurgers, L. J. (2024). Unveiling cellular and molecular aspects of ascending thoracic aortic aneurysms and dissections. Basic Research in Cardiology, 119(3), 371-395. https://doi.org/10.1007/s00395-024-01053-1
- Singh, A., Kraaijeveld, A. O., Curaj, A., Wichapong, K., Hammerich, L., de Jager, S. C. A., Bot, I., Atamas, S. P., van Berkel, T. J. C., Jukema, J. W., Comerford, I., Mccoll, S. R., Mees, B., Heemskerk, J. W. M., Nicolaes, G. A. F., Hackeng, T., Liehn, E. A., Tacke, F., & Biessen, E. A. L. (2024). CCL18 aggravates atherosclerosis by inducing CCR6-dependent T-cell influx and polarization. Frontiers in Immunology, 15, Article 1327051. https://doi.org/10.3389/fimmu.2024.1327051
- Davies, H., Russell, D. A., Mees, B. M. E., & Scott, D. J. A. (2024). End of life care in vascular surgery. British Journal of Surgery, 111(5), Article znae124. https://doi.org/10.1093/bjs/znae124
- Mees, B. M. E., & Shalhoub, J. (2024). Vascular Radiation Safety Education: Don't Stay Passive but Go Massive. European Journal of Vascular and Endovascular Surgery, 67(5), 847. https://doi.org/10.1016/j.ejvs.2024.01.075
- You, W., Knoops, K., Berendschot, T. T. J. M., Benedikter, B. J., Webers, C. A. B., Reutelingsperger, C. P. M., & Gorgels, T. G. M. F. (2024). PGC-1a mediated mitochondrial biogenesis promotes recovery and survival of neuronal cells from cellular degeneration. Cell Death Discovery, 10(1), Article 180. https://doi.org/10.1038/s41420-024-01953-0
- Pinto, E., Viegas, C., Martins, P. V., Marreiros, C., Nascimento, T., Schurgers, L., & Simes, D. (2024). Mediterranean Diet Favors Vitamin K Intake: A Descriptive Study in a Mediterranean Population. Nutrients, 16(8), Article 1098. https://doi.org/10.3390/nu16081098
- Simons, J., Mees, B., MacLaren, G., Fraser, J. F., Zaaqoq, A. M., Cho, S.-M., Patel, B. M., Brodie, D., Belohlávek, J., Belliato, M., Jung, J.-S., Salazar, L., Meani, P., Mariani, S., Di Mauro, M., Yannopoulos, D., Broman, L. M., Chen, Y.-S., Riera, J., ... Lorusso, R. (2024). Evolution of distal limb perfusion management in adult peripheral venoarterial extracorporeal membrane oxygenation with femoral artery cannulation. Perfusion, 39(1_suppl), 23S-38S. https://doi.org/10.1177/02676591241236650
- Lemmens, T. P., Bröker, V., Rijpkema, M., Hughes, C. C. W., Schurgers, L. J., & Cosemans, J. M. E. M. (2024). Fundamental considerations for designing endothelialized in vitro models of thrombosis. Thrombosis Research, 236, 179-190. https://doi.org/10.1016/j.thromres.2024.03.004
- Veltrop, R. J. A., Kukk, M. M., Topouzidou, K., Didden, L., Muchir, A., van Steenbeek, F. G., Schurgers, L. J., & Harakalova, M. (2024). From gene to mechanics: a comprehensive insight into the mechanobiology of LMNA mutations in cardiomyopathy. Cell Communication and Signaling, 22(1), Article 197. https://doi.org/10.1186/s12964-024-01546-5
- Busch, M. H., Ysermans, R., Aendekerk, J., Timmermans, S. A., Potjewijd, J., Damoiseaux, J., Spronk, H. M. H., Ten Cate, H., Reutelingsperger, C., Nagy, M., & van Paassen, P. (2024). The intrinsic coagulation pathway plays a dominant role in driving hypercoagulability in ANCA-Associated Vasculitis. Blood advances, 8(5), 1295-1304. https://doi.org/10.1182/bloodadvances.2023011937
- Duijvelaar, E., Pan, X., Bogaard, H. J., Eringa, E. C., & Aman, J. (2024). Imatinib treatment improves hyperglycaemic dysregulation in severe COVID-19: a secondary analysis of blood biomarkers in a randomised controlled trial. Critical Care, 28(1), Article 65. https://doi.org/10.1186/s13054-024-04829-y
- Woudstra, J., Feenstra, R. G. T., Vink, C. E. M., Marques, K. M. J., Boerhout, C. K. M., de Jong, E. A. M., de Waard, G. A., van de Hoef, T. P., Chamuleau, S. A. J., Eringa, E. C., Piek, J. J., Appelman, Y., & Beijk, M. A. M. (2024). Comparison of the Diagnostic Yield of Intracoronary Acetylcholine Infusion and Acetylcholine Bolus Injection Protocols During Invasive Coronary Function Testing. American Journal of Cardiology, 217, 49-58. https://doi.org/10.1016/j.amjcard.2024.01.038
- Li, F., Chen, L., Zhong, S., Chen, J., Cao, Y., Yu, H., Ran, H., Yin, Y., Reutelingsperger, C., Shu, S., & Ling, Z. (2024). Collagen-Targeting Self-Assembled Nanoprobes for Multimodal Molecular Imaging and Quantification of Myocardial Fibrosis in a Rat Model of Myocardial Infarction. ACS Nano, 18(6), 4886-4902. https://doi.org/10.1021/acsnano.3c09801
- Lu, C., Donners, M. M. P. C., de Baaij, J. B. J., Jin, H., Otten, J. J. T., Manca, M., van Zonneveld, A. J., Jukema, J. W., Kraaijeveld, A., Kuiper, J., Pasterkamp, G., Mees, B., Sluimer, J. C., Cavill, R., Karel, J. M. H., Goossens, P., & Biessen, E. A. L. (2024). Identification of a gene network driving the attenuated response to lipopolysaccharide of monocytes from hypertensive coronary artery disease patients. Frontiers in Immunology, 15, Article 1286382. https://doi.org/10.3389/fimmu.2024.1286382
- Davies, H., Safdar, N. Z., Yi Kwan, J., Jain, K., Sciberras, P., Hurlow, A., Po Tam, S. K., Coughlin, P., Mees, B. M. E., & Scott, D. J. A. (2024). End of Life Care for Unplanned Vascular Admissions. Annals of Vascular Surgery, 99, 280-289. https://doi.org/10.1016/j.avsg.2023.08.024
- Reutelingsperger, C. P. M., Gijbels, M. J., Spronk, H., Van Oerle, R., Schrijver, R., Ekhart, P., de Kimpe, S., & Nicolaes, G. A. F. (2024). M6229 Protects against Extracellular-Histone-Induced Liver Injury, Kidney Dysfunction, and Mortality in a Rat Model of Acute Hyperinflammation. International Journal of Molecular Sciences, 25(3), Article 1376. https://doi.org/10.3390/ijms25031376
- You, W., Knoops, K., Boesten, I., Berendschot, T. T. J. M., van Zandvoort, M. A. M. J., Benedikter, B. J., Webers, C. A. B., Reutelingsperger, C. P. M., & Gorgels, T. G. M. F. (2024). A time window for rescuing dying retinal ganglion cells. Cell Communication and Signaling, 22(1), Article 88. https://doi.org/10.1186/s12964-023-01427-3
- Nordanstig, J., Behrendt, C.-A., Baumgartner, I., Belch, J., Back, M., Fitridge, R., Hinchliffe, R., Lejay, A., Mills, J. L., Rother, U., Sigvant, B., Spanos, K., Szeberin, Z., van de Water, W., ESVS Guideline Committee, & Mees, B. (2024). Editor's Choice - European Society for Vascular Surgery (ESVS) 2024 Clinical Practice Guidelines on the Management of Asymptomatic Lower Limb Peripheral Arterial Disease and Intermittent Claudication. European Journal of Vascular and Endovascular Surgery, 67(1), 9-96. Advance online publication. https://doi.org/10.1016/j.ejvs.2023.08.067
- Frankort, J., Krabbe, J., Otte, N., Doukas, P., Krabbe, H., Jacobs, M. J., & Gombert, A. (2024). Posttraumatic stress disorder and quality of life in patients after open thoracoabdominal aortic repair. Vasa-European Journal of Vascular Medicine, 53(1), 45-52. https://doi.org/10.1024/0301-1526/a001103
- Simons, J., Di Mauro, M., Mariani, S., Ravaux, J., van der Horst, I. C. C., Driessen, R. G. H., Sels, J. W., Delnoij, T., Brodie, D., Abrams, D., Mueller, T., Taccone, F. S., Belliato, M., Broman, M. L., Malfertheiner, M. V., Boeken, U., Fraser, J., Wiedemann, D., Belohlavek, J., ... Lorusso, R. (2024). Bilateral Femoral Cannulation Is Associated With Reduced Severe Limb Ischemia-Related Complications Compared With Unilateral Femoral Cannulation in Adult Peripheral Venoarterial Extracorporeal Membrane Oxygenation: Results From the Extracorporeal Life Support Registry. Critical Care Medicine, 52(1), 80-91. https://doi.org/10.1097/CCM.0000000000006040
- 2023
- Mulder, M. M. G., Schellens, J., Sels, J.-W. E. M., van Rosmalen, F., Hulshof, A.-M., de Vries, F., Segers, R., Mihl, C., van Mook, W. N. K. A., Bast, A., Spronk, H. M. H., Henskens, Y. M. C., van der Horst, I. C. C., ten Cate, H., Schurgers, L. J., Drent, M., & van Bussel, B. C. T. (2023). Higher levels of circulating desphospho-uncarboxylated matrix Gla protein over time are associated with worse survival: the prospective Maastricht Intensive Care COVID cohort. Journal of Intensive Care, 11(1), Article 63. https://doi.org/10.1186/s40560-023-00712-0
- Huckriede, J. B., Beurskens, D. M. H., Wildhagen, K. C. C. A., Reutelingsperger, C. P. M., Wichapong, K., & Nicolaes, G. A. F. (2023). Design and characterization of novel activated protein C variants for the proteolysis of cytotoxic extracellular histone H3. Journal of Thrombosis and Haemostasis, 21(12), 3557-3567. https://doi.org/10.1016/j.jtha.2023.08.023
- Potjewijd, J., Tobal, R., Boomars, K. A., van Empel, V. V. P. M., de Vries, F., Damoiseaux, J. G. M. C., Schurgers, L. J., & van Paassen, P. (2023). Plasma Dephosphorylated-Uncarboxylated Matrix Gla-Protein in Systemic Sclerosis Patients: Biomarker Potential for Vascular Calcification and Inflammation. Diagnostics, 13(23), Article 3526. https://doi.org/10.3390/diagnostics13233526
- Sun, S., Campello, E., Zou, J., Konings, J., Huskens, D., Wan, J., Fernández, D. I., Reutelingsperger, C., Ten Cate, H., Toffanin, S., Bulato, C., de Groot, P. G., de Laat, B., Simioni, P., Heemskerk, J. W. M., & Roest, M. (2023). Crucial roles of red blood cells and platelets in whole blood thrombin generation. Blood advances, 7(21), 6717-6731. https://doi.org/10.1182/bloodadvances.2023010027