PI group Paul Volders
- 2024
- Patel, K. H. K., Bajaj, N., Statton, B. K., Bishop, M. J., Herath, N. S., Stoks, J., Li, X., Sau, A., Nyamakope, K., Davidson, R., Savvidou, S., Agha-Jaffar, D., Coghlin, J. A., Brezitski, M., Bergman, H., Berry, A., Ardissino, M., de Marvao, A. S. M., Cousins, J., ... Ng, F. S. (2024). Bariatric surgery partially reverses subclinical proarrhythmic structural, electrophysiological, and autonomic changes in obesity. Heart Rhythm, 21(11), 2282-2294. https://doi.org/10.1016/j.hrthm.2024.05.052
- Kaya, Y. S., Stoks, J., Hazelaar, C., van Elmpt, W., Gommers, S., Volders, P. G. A., Verhoeven, K., & ter Bekke, R. M. A. (2024). 3D-targeted, electrocardiographic imaging-aided stereotactic radioablation for ventricular tachycardia storm: a case report. European Heart Journal - Case Reports, 8(10), Article ytae541. https://doi.org/10.1093/ehjcr/ytae541
- Ramos-Prada, A., Redondo-Rodríguez, A., Roca-Luque, I., Porta-Sánchez, A., Ter Bekke, R. M. A., Quintanilla, J. G., Sánchez-González, J., Peinado, R., Merino, J. L., Cluitmans, M., Holtackers, R. J., Marina-Breysse, M., Galán-Arriola, C., Enríquez-Vázquez, D., Vázquez-Calvo, S., Alfonso-Almazán, J. M., Pizarro, G., Ibáñez, B., González-Ferrer, J. J., ... Filgueiras-Rama, D. (2024). Novel systematic processing of cardiac magnetic resonance imaging identifies target regions associated with infarct-related ventricular tachycardia. EP Europace, 26(10), Article euae244. https://doi.org/10.1093/europace/euae244
- Verheul, L. M., Hoeksema, W. F., Groeneveld, S. A., Mulder, B. A., Bootsma, M., Alings, M., Evertz, R., Blank, A. C., Kammeraad, J. A. E., Clur, S.-A. B., Yap, S.-C., Postema, P. G., Wilde, A. A. M., Volders, P. G. A., & Hassink, R. J. (2024). Comparing Adolescent- and Adult-Onset Unexplained Cardiac Arrest - Results from the Dutch Idiopathic VF registry. Heart Rhythm, 21(10), 1779-1786. https://doi.org/10.1016/j.hrthm.2024.03.031
- Tohidinezhad, F., Nürnberg, L., Vaassen, F., Ma Ter Bekke, R., Jwl Aerts, H., El Hendriks, L., Dekker, A., De Ruysscher, D., & Traverso, A. (2024). Prediction of new-onset atrial fibrillation in patients with non-small cell lung cancer treated with curative-intent conventional radiotherapy. Radiotherapy and Oncology, 201, Article 110544. Advance online publication. https://doi.org/10.1016/j.radonc.2024.110544
- Buonocunto, M., Lyon, A., Delhaas, T., Heijman, J., & Lumens, J. (2024). Electrophysiological effects of stretch-activated ion channels: a systematic computational characterization. The Journal of Physiology, 602(18), 4585-4604. https://doi.org/10.1113/JP284439
- Bodi, I., Mettke, L., Michaelides, K., Hornyik, T., Meier, S., Nimani, S., Perez-Feliz, S., El-Battrawy, I., Bugger, H., Zehender, M., Brunner, M., Heijman, J., & Odening, K. E. (2024). Beneficial normalization of cardiac repolarization by carnitine in transgenic short QT syndrome type 1 rabbit models. Cardiovascular Research, 120(13), 1550-1561. https://doi.org/10.1093/cvr/cvae149
- Serinagaoglu Dogrusoz, Y., Bear, L., Bergquist, J. A., Rababah, A., Good, W., Stoks, J., Svehlikova, J., van Dam, E., Brooks, D. H., & MacLeod, R. (2024). Evaluation of five methods for the interpolation of bad leads in the solution of the inverse electrocardiography problem. Physiological Measurement, 45(9), Article 095012. https://doi.org/10.1088/1361-6579/ad74d6
- Fakuade, F. E., Hubricht, D., Möller, V., Sobitov, I., Liutkute, A., Döring, Y., Seibertz, F., Gerloff, M., Pronto, J. R. D., Haghighi, F., Brandenburg, S., Alhussini, K., Ignatyeva, N., Bonhoff, Y., Kestel, S., El-Essawi, A., Jebran, A. F., Großmann, M., Danner, B. C., ... Voigt, N. (2024). Impaired Intracellular Calcium Buffering Contributes to the Arrhythmogenic Substrate in Atrial Myocytes From Patients With Atrial Fibrillation. Circulation, 150(7), 544-559. https://doi.org/10.1161/CIRCULATIONAHA.123.066577
- Sabbag, A., Amoroso, G., Tomer, O., Conte, G., Beinart, R., Nof, E., Ozkartal, T., Ollitrault, P., Laredo, M., Tovia-Brodie, O., Gandjbakhch, E., de Benedictis, M., ter Bekke, R. M. A., & Milman, A. (2024). Clinical differences between drug-induced type 1 Brugada pattern and syndrome. Journal of Arrhythmia, 40(4), 982-990. https://doi.org/10.1002/joa3.13053
- Trayanova, N. A., Lyon, A., Shade, J., & Heijman, J. (2024). Computational modeling of cardiac electrophysiology and arrhythmogenesis: toward clinical translation. Physiological Reviews, 104(3), 1265-1333. https://doi.org/10.1152/physrev.00017.2023
- Heijman, J., & Dobrev, D. (2024). Spexin Hormone Signaling and Atrial Fibrillation: The Knowns and Unknowns. Circulation, 150(2), 128-131. https://doi.org/10.1161/CIRCULATIONAHA.124.070016
- Stoks, J., Patel, K. H. K., van Rees, B., Nguyen, U. C., Mihl, C., Deissler, P. M., Ter Bekke, R. M. A., Peeters, R., Vijgen, J., Dendale, P., Ng, F. S., Cluitmans, M. J. M., & Volders, P. G. A. (2024). Variant patterns of electrical activation and recovery in normal human hearts revealed by noninvasive electrocardiographic imaging. EP Europace, 26(7), Article euae172. https://doi.org/10.1093/europace/euae172
- Deissler, P. M., Volders, P. G. A., & Ter Bekke, R. M. A. (2024). The Electromechanical Window for Arrhythmia-Risk Assessment. Heart Rhythm. Advance online publication. https://doi.org/10.1016/j.hrthm.2024.06.012
- Verheul, L. M., Guglielmo, M., Groeneveld, S. A., Kirkels, F. P., Scrocco, C., Cramer, M. J., Bootsma, M., Kapel, G. F. L., Alings, M., Evertz, R., Mulder, B. A., Prakken, N. H. J., Balt, J. C., Volders, P. G. A., Hirsch, A., Yap, S. C., Postema, P. G., Nijveldt, R., Velthuis, B. K., ... Hassink, R. J. (2024). Mitral Annular Disjunction in Idiopathic Ventricular Fibrillation Patients: Just a Bystander or a Potential Cause?European Heart Journal Cardiovascular Imaging, 25(6), 764-770. https://doi.org/10.1093/ehjci/jeae054
- Niskala, A., Heijman, J., Dobrev, D., Jespersen, T., & Saljic, A. (2024). Targeting the NLRP3 inflammasome signalling for the management of atrial fibrillation. British Journal of Pharmacology. Advance online publication. https://doi.org/10.1111/bph.16470
- Cluitmans, M. J. M., Plank, G., & Heijman, J. (2024). Digital twins for cardiac electrophysiology: state of the art and future challenges. Herzschrittmachertherapie und Elektrophysiologie, 35(2), 118-123. https://doi.org/10.1007/s00399-024-01014-0
- Verheul, L. M., Groeneveld, S. A., Stoks, J., Hoeksema, W. F., Cluitmans, M. J. M., Postema, P. G., Wilde, A. A. M., Volders, P. G. A., & Hassink, R. J. (2024). The Dutch Idiopathic Ventricular Fibrillation Registry: progress report on the quest to identify the unidentifiable. Netherlands Heart Journal, 32(6), 238-244. https://doi.org/10.1007/s12471-024-01870-y
- Steffens, S., Schröder, K., Krüger, M., Maack, C., Streckfuss-Bömeke, K., Backs, J., Backofen, R., Baeßler, B., Devaux, Y., Gilsbach, R., Heijman, J., Knaus, J., Kramann, R., Linz, D., Lister, A. L., Maatz, H., Maegdefessel, L., Mayr, M., Meder, B., ... Kohl, P. (2024). The challenges of research data management in cardiovascular science: a DGK and DZHK position paper-executive summary. Clinical research in cardiology, 113(5), 672-679. https://doi.org/10.1007/s00392-023-02303-3
- Heijman, J., & Madreiter-Sokolowski, C. T. (2024). Is ageing a modifiable risk factor for atrial fibrillation?Cardiovascular Research, 120(5), 440-442. https://doi.org/10.1093/cvr/cvae040
- Willems, E., Janssens, K. L. P. M., Dekker, L. R. C., van de Vosse, F. N., Cluitmans, M. J. M., & Bovendeerd, P. H. M. (2024). Strain-controlled electrophysiological wave propagation alters in silico scar-based substrate for ventricular tachycardia. Frontiers in physiology, 15, Article 1330157. https://doi.org/10.3389/fphys.2024.1330157
- Stevens, R. R. F., Hazelaar, C., Bogowicz, M., Ter Bekke, R. M. A., Volders, P. G. A., Verhoeven, K., de Ruysscher, D., Verhoeff, J. J. C., Fast, M. F., Mandija, S., Cvek, J., Knybel, L., Dvorak, P., Blanck, O., & van Elmpt, W. (2024). A Framework for Assessing the Effect of Cardiac and Respiratory Motion for Stereotactic Arrhythmia Radioablation Using a Digital Phantom With a 17-Segment Model: A STOPSTORM.eu Consortium Study. International Journal of Radiation Oncology Biology Physics, 118(2), 533-542. https://doi.org/10.1016/j.ijrobp.2023.08.059
- Stoks, J., Langfield, P., & Cluitmans, M. J. M. (2024). Methodological and Mechanistic Considerations in Local Repolarization Mapping. JACC: Clinical Electrophysiology, 10(2), 376-377. https://doi.org/10.1016/j.jacep.2023.12.018
- Saljic, A., & Heijman, J. (2024). P2X7 receptors: central drivers of the neuro-cardiac link between atrial fibrillation and depression?EP Europace, 26(2), Article euae023. https://doi.org/10.1093/europace/euae023
- 2023
- Garcia, J. G., Arya, A., Dinov, B., Bollmann, A., ter Bekke, R. M. A., Vernooy, K., Dagres, N., Hindricks, G., & Darma, A. (2023). Impact of repeat ablation of ventricular tachycardia in patients with structural heart disease. EP Europace, 26(1), Article euad367. https://doi.org/10.1093/europace/euad367
- Verheul, L. M., van der Ree, M. H., Groeneveld, S. A., Mulder, B. A., Christiaans, I., Kapel, G. F. L., Alings, M., Bootsma, M., Barge-Schaapveld, D. Q. C. M., Balt, J. C., Yap, S.-C., Krapels, I. P. C., Ter Bekke, R. M. A., Volders, P. G. A., van der Crabben, S. N., Postema, P. G., Wilde, A. A. M., Dooijes, D., Baas, A. F., & Hassink, R. J. (2023). The genetic basis of apparently idiopathic ventricular fibrillation: a retrospective overview. EP Europace, 25(11), Article euad336. https://doi.org/10.1093/europace/euad336
- Kaya, Y. S., Stoks, J., Gommers, S., Holtackers, R. J., Duijsings, R., Vernooy, K., Volders, P., & Ter Bekke, R. (2023). Optimal pixel signal intensity threshold for the assessment of endocardial left-ventricular scar by 3D dark blood MRI compared to bipolar voltage electro-anatomical mapping. European Heart Journal, 44.
- Herrera, N. T., Zhang, X., Ni, H., Maleckar, M. M., Heijman, J., Dobrev, D., Grandi, E., & Morotti, S. (2023). Dual effects of the small-conductance Ca2+-activated K+ current on human atrial electrophysiology and Ca2+-driven arrhythmogenesis: an in silico study. American Journal of Physiology-heart and Circulatory Physiology, 325(4), H896-H908. https://doi.org/10.1152/ajpheart.00362.2023
- Filgueiras-Rama, D., Ramos-Prada, A., & Cluitmans, M. J. M. (2023). Arrhythmogenic vulnerability of reentrant pathways in post-infarct ventricular tachycardia assessed by advanced computational modelling. EP Europace, 25(9), Article euad258. https://doi.org/10.1093/europace/euad258
- Remme, C. A., Heijman, J., Gomez, A. M., Zaza, A., & Odening, K. E. (2023). 25 years of basic and translational science in EP Europace: novel insights into arrhythmia mechanisms and therapeutic strategies. EP Europace, 25(8), 1-11. Article euad210. https://doi.org/10.1093/europace/euad210
- Heijman, J., & Christ, T. (2023). Mind the gap: Leak currents and induced pluripotent stem cell-derived cardiomyocytes in translational cardiac electrophysiology. EP Europace, 25(9), Article euad236. https://doi.org/10.1093/europace/euad236
- Saljic, A., Heijman, J., & Dobrev, D. (2023). Recent Advances in Antiarrhythmic Drug Therapy. Drugs, 83(13), 1147 - 1160. https://doi.org/10.1007/s40265-023-01923-3
- Bergeman, A. T. J., Hoeksema, W. F. N., van der Ree, M. H., Boersma, L. V. A., Yap, S.-C., Verheul, L. M. G., Hassink, R. J., van der Crabben, S. N., Volders, P. G. A., van der Werf, C., Wilde, A. A. M. G., Postema, P. G., & European Reference Network for rare, low prevalence and complex diseases of the heart: ERN GUARD-Heart (2023). Outcomes in Dutch DPP6 risk haplotype for familial idiopathic ventricular fibrillation: a focused update. Netherlands Heart Journal, 31(7-8), 309-314. https://doi.org/10.1007/s12471-023-01792-1
- Heijman, J., & Dobrev, D. (2023). Determinants and therapeutic potential of calcium handling abnormalities in atrial fibrillation: What can we learn from computer models?The Journal of Physiology, 601(13), 2545-2546. https://doi.org/10.1113/jp283817
- Meier, S., Grundland, A., Dobrev, D., Volders, P. G. A., & Heijman, J. (2023). In silico analysis of the dynamic regulation of cardiac electrophysiology by K(v)11.1 ion-channel trafficking. The Journal of Physiology, 601(13), 2711-2731. https://doi.org/10.1113/JP283976
- Wang, X., Song, J., Yuan, Y., Li, L., Abu-Taha, I., Heijman, J., Sun, L., Dobrev, S., Kamler, M., Xie, L., Wehrens, X. H. T., Horrigan, F. T., Dobrev, D., & Li, N. (2023). Downregulation of FKBP5 Promotes Atrial Arrhythmogenesis. Circulation Research, 133(1), E1-E16. https://doi.org/10.1161/CIRCRESAHA.122.322213
- Cluitmans, M., Walton, R., & Plank, G. (2023). Editorial: Computational methods in cardiac electrophysiology. Frontiers in physiology, 14(1), Article 1231342. https://doi.org/10.3389/fphys.2023.1231342
- ter Bekke, R. M. A., de Schouwer, K., Conti, S., Claes, G. R. F., Vanoevelen, J., Gommers, S., Helderman-van den Enden, A. T. J. M., & Brunner-LaRocca, H.-P. (2023). Juvenile-onset multifocal atrial arrhythmias, atrial standstill and compound heterozygosity of genetic variants in TAF1A: sentinel event for evolving dilated cardiomyopathy-a case report. European Heart Journal - Case Reports, 7(6), Article ytad255. https://doi.org/10.1093/ehjcr/ytad255
- Rijks, J. H. J., Lankveld, T., Manusama, R., Broers, B., van Stipdonk, A. M. W., Chaldoupi, S. M., ter Bekke, R. M. A., Schotten, U., Linz, D., Luermans, J. G. L. M., & Vernooy, K. (2023). Left Bundle Branch Area Pacing and Atrioventricular Node Ablation in a Single-Procedure Approach for Elderly Patients with Symptomatic Atrial Fibrillation. Journal of Clinical Medicine, 12(12), Article 4028. https://doi.org/10.3390/jcm12124028
- Nies, H. M. J. M., Martens, B., Gommers, S., Bijvoet, G. P., Wildberger, J. E., Ter Bekke, R. M. A., Holtackers, R. J., & Mihl, C. (2023). Myocardial Scar Detection Using High-Resolution Free-Breathing 3D Dark-Blood and Standard Breath-Holding 2D Bright-Blood Late Gadolinium Enhancement MRI: A Comparison of Observer Confidence. Topics in Magnetic Resonance Imaging, 32(3), 27-32. https://doi.org/10.1097/RMR.0000000000000304
- Isaacs, A., Barysenka, A., ter Bekke, R. M. A., van den Enden, A. T. J. M. H., van den Wijngaard, A., Volders, P. G. A., & Stoll, M. (2023). Standing genetic variation affects phenotypic heterogeneity in an SCN5A-mutation founder population with excess sudden cardiac death. Heart Rhythm, 20(5), 720-727. https://doi.org/10.1016/j.hrthm.2023.02.004
- Heijman, J., Zhou, X., Morotti, S., Molina, C. E., Abu-Taha, I. H., Tekook, M., Jespersen, T., Zhang, Y., Dobrev, S., Milting, H., Gummert, J., Karck, M., Kamler, M., El-Armouche, A., Saljic, A., Grandi, E., Nattel, S., & Dobrev, D. (2023). Enhanced Ca2+-Dependent SK-Channel Gating and Membrane Trafficking in Human Atrial Fibrillation. Circulation Research, 132(9), E116-E133. https://doi.org/10.1161/CIRCRESAHA.122.321858
- Cluitmans, M. J. M., Bayer, J., Bear, L. R., Ter Bekke, R. M. A., Heijman, J., Coronel, R., & Volders, P. G. A. (2023). The circle of reentry: Characteristics of trigger-substrate interaction leading to sudden cardiac arrest. Frontiers in Cardiovascular Medicine, 10, Article 1121517. https://doi.org/10.3389/fcvm.2023.1121517
- Grehn, M., Mandija, S., Miszczyk, M., Krug, D., Tomasik, B., Stickney, K. E., Alcantara, P., Alongi, F., Anselmino, M., Aranda, R. S., Balgobind, B. V., Boda-Heggemann, J., Boldt, L. H., Bottoni, N., Cvek, J., Elicin, O., De Ferrari, G. M., Hassink, R. J., Hazelaar, C., ... Verhoeff, J. (2023). STereotactic Arrhythmia Radioablation (STAR): the Standardized Treatment and Outcome Platform for Stereotactic Therapy Of Re-entrant tachycardia by a Multidisciplinary consortium (STOPSTORM.eu) and review of current patterns of STAR practice in Europe. EP Europace, 25(4), 1284-1295. https://doi.org/10.1093/europace/euac238
- Leao, S., Luermans, J., Vernooy, K., ter Bekke, R., den Uijl, D., Linz, D., & Chaldoupi, S.-M. (2023). The great deceiver: a case series of 'double fire' atrioventricular nodal response. European Heart Journal - Case Reports, 7(4), Article ytad162. https://doi.org/10.1093/ehjcr/ytad162
- Stoks, J., Bear, L. R., Vijgen, J., Dendale, P., Peeters, R., Volders, P. G. A., & Cluitmans, M. J. M. (2023). Understanding repolarization in the intracardiac unipolar electrogram: A long-lasting controversy revisited. Frontiers in physiology, 14, Article 1158003. https://doi.org/10.3389/fphys.2023.1158003
- Seibertz, F., Sutanto, H., Dulk, R., Pronto, J. R. D., Springer, R., Rapedius, M., Liutkute, A., Ritter, M., Jung, P. L., Stelzer, L., Husgen, L. M., Klopp, M., Rubio, T., Fakuade, F. E., Mason, F. E., Hartmann, N., Pabel, S., Streckfuss-Bomeke, K., Cyganek, L., ... Voigt, N. (2023). Electrophysiological and calcium-handling development during long-term culture of human-induced pluripotent stem cell-derived cardiomyocytes. Basic Research in Cardiology, 118(1), Article 14. https://doi.org/10.1007/s00395-022-00973-0
- Gawalko, M., Saljic, A., Li, N., Abu-Taha, I., Jespersen, T., Linz, D., Nattel, S., Heijman, J., Fender, A., & Dobrev, D. (2023). Adiposity-associated atrial fibrillation: molecular determinants, mechanisms, and clinical significance. Cardiovascular Research, 119(3), 614-630. https://doi.org/10.1093/cvr/cvac093
- Dobrev, D., Heijman, J., Hiram, R., Li, N., & Nattel, S. (2023). Inflammatory signalling in atrial cardiomyocytes: a novel unifying principle in atrial fibrillation pathophysiology. Nature Reviews Cardiology, 20(3), 145-167. https://doi.org/10.1038/s41569-022-00759-w