• 2018
    • Vroemen, W. H. M., de Boer, D., Streng, A. S., Mingels, A. M. A., & Meex, S. J. R. (2018). Elevated Cardiac Troponin T in Skeletal Myopathies: Skeletal TnT Cross-Reactivity and/or Cardiac TnT Expression?Journal of the American College of Cardiology, 72(3), 347-349. https://doi.org/10.1016/j.jacc.2018.05.017
    • Prins, B. P., Mead, T. J., Brody, J. A., Sveinbjornsson, G., Ntalla, I., Bihlmeyer, N. A., van den Berg, M., Bork-Jensen, J., Cappellani, S., Van Duijvenboden, S., Klena, N. T., Gabriel, G. C., Liu, X., Gulec, C., Grarup, N., Haessler, J., Hall, L. M., Iorio, A., Isaacs, A., ... Jamshidi, Y. (2018). Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6. Genome Biology, 19(1), Article 87. https://doi.org/10.1186/s13059-018-1457-6
    • Vajen, T., Koenen, R. R., Werner, I., Staudt, M., Projahn, D., Curaj, A., Sonmez, T. T., Simsekyilmaz, S., Schumacher, D., Mollmann, J., Hackeng, T. M., von Hundelshausen, P., Weber, C., & Liehn, E. A. (2018). Blocking CCL5-CXCL4 heteromerization preserves heart function after myocardial infarction by attenuating leukocyte recruitment and NETosis. Scientific Reports, 8(1), Article 10647. https://doi.org/10.1038/s41598-018-29026-0
    • Whitworth, J., Smith, P. S., Martin, J.-E., West, H., Luchetti, A., Rodger, F., Clark, G., Carss, K., Stephens, J., Stirrups, K., Penkett, C., Mapeta, R., Ashford, S., Megy, K., Shakeel, H., Ahmed, M., Adlard, J., Barwell, J., Brewer, C., ... NIHR BioResource Rare Diseases Consortium (2018). Comprehensive Cancer-Predisposition Gene Testing in an Adult Multiple Primary Tumor Series Shows a Broad Range of Deleterious Variants and Atypical Tumor Phenotypes. American Journal of Human Genetics, 103(1), 3-18. https://doi.org/10.1016/j.ajhg.2018.04.013
    • Ito, Y., Carss, K. J., Duarte, S. T., Hartley, T., Keren, B., Kurian, M. A., Marey, I., Charles, P., Mendonca, C., Nava, C., Pfundt, R., Sanchis-Juan, A., van Bokhoven, H., van Essen, A., van Ravenswaaij-Arts, C., Boycott, K. M., Kernohan, K. D., Dyack, S., Raymond, F. L., ... Care4Rare Canada Consortium (2018). De Novo Truncating Mutations in WASF1 Cause Intellectual Disability with Seizures. American Journal of Human Genetics, 103(1), 144-153. https://doi.org/10.1016/j.ajhg.2018.06.001
    • Winter, C., Silvestre-Roig, C., Ortega-Gomez, A., Lemnitzer, P., Poelman, H., Schumski, A., Winter, J., Drechsler, M., de Jong, R., Immler, R., Sperandio, M., Hristov, M., Zeller, T., Nicolaes, G. A. F., Weber, C., Viola, J. R., Hidalgo, A., Scheiermann, C., & Soehnlein, O. (2018). Chrono-pharmacological Targeting of the CCL2-CCR2 Axis Ameliorates Atherosclerosis. Cell Metabolism, 28(1), 175-182.e5. https://doi.org/10.1016/j.cmet.2018.05.002
    • Amin, E. E., van Kuijk, S. M. J., Joore, M. A., Prandoni, P., ten Cate, H., & ten Cate-Hoek, A. J. (2018). Development and Validation of a Practical Two-Step Prediction Model and Clinical Risk Score for Post-Thrombotic Syndrome. Thrombosis and Haemostasis, 118(7), 1242-1249. https://doi.org/10.1055/s-0038-1655743
    • van Doorn, P., Rosing, J., Duckers, C., Hackeng, T. M., Simioni, P., & Castoldi, E. (2018). Factor V Has Anticoagulant Activity in Plasma in the Presence of TFPI: Difference between FV1 and FV2. Thrombosis and Haemostasis, 118(7), 1194-1202. https://doi.org/10.1055/s-0038-1656549
    • Moenen, F. C. J. I., Nelemans, P. J., Schols, S. E. M., Schouten, H. C., Henskens, Y. M. C., & Beckers, E. A. M. (2018). The diagnostic accuracy of bleeding assessment tools for the identification of patients with mild bleeding disorders: A systematic review. Haemophilia, 24(4), 525-535. https://doi.org/10.1111/hae.13486
    • Swieringa, F., Spronk, H. M. H., Heemskerk, J. W. M., & van der Meijden, P. E. J. (2018). Integrating platelet and coagulation activation in fibrin clot formation. Research and practice in thrombosis and haemostasis, 2(3), 450-460. https://doi.org/10.1002/rth2.12107
    • Kimenai, D. M., Janssen, E. B. N. J., Eggers, K. M., Lindahl, B., den Ruijter, H. M., Bekers, O., Appelman, Y., & Meex, S. J. R. (2018). Sex-Specific Versus Overall Clinical Decision Limits for Cardiac Troponin I and T for the Diagnosis of Acute Myocardial Infarction: A Systematic Review. Clinical Chemistry, 64(7), 1034-1043. https://doi.org/10.1373/clinchem.2018.286781
    • Vaidya, A., Kleinegris, M.-C., Severens, J. L., Ramaekers, B. L., ten Cate-Hoek, A. J., ten Cate, H., & Joore, M. A. (2018). Comparison of EQ-5D and SF-36 in untreated patients with symptoms of intermittent claudication. Journal of Comparative Effectiveness Research, 7(6), 535-548. https://doi.org/10.2217/cer-2017-0029
    • van Bussel, B. C. T., Henry, R. M. A., Schalkwijk, C. G., Dekker, J. M., Nijpels, G., Feskens, E. J. M., & Stehouwer, C. D. A. (2018). Alcohol and red wine consumption, but not fruit, vegetables, fish or dairy products, are associated with less endothelial dysfunction and less low-grade inflammation: the Hoorn Study. European Journal of Nutrition, 57(4), 1409-1419. https://doi.org/10.1007/s00394-017-1420-4
    • Panova-Noeva, M., Schulz, A., Spronk, H. M., Beicht, A., Laubert-Reh, D., van Oerle, R., Arnold, N., Prochaska, J. H., Blettner, M., Beutel, M., Pfeiffer, N., Munzel, T., Lackner, K. J., ten Cate, H., & Wild, P. S. (2018). Clinical Determinants of Thrombin Generation Measured in Presence and Absence of Platelets-Results from the Gutenberg Health Study. Thrombosis and Haemostasis, 118(5), 873-882. https://doi.org/10.1055/s-0038-1641565
    • Lin, H., van Setten, J., Smith, A. V., Bihlmeyer, N. A., Warren, H. R., Brody, J. A., Radmanesh, F., Hall, L., Grarup, N., Muller-Nurasyid, M., Boutin, T., Verweij, N., Lin, H. J., Li-Gao, R., van den Berg, M. E., Marten, J., Weiss, S., Prins, B. P., Haessler, J., ... Isaacs, A. (2018). Common and Rare Coding Genetic Variation Underlying the Electrocardiographic PR Interval. Circulation: Genomic and Precision Medicine, 11(5), Article e002037 . https://doi.org/10.1161/CIRCGEN.117.002037
    • ten Cate, H., Olie, R. H., ten Cate-Hoek, A. J., & Henskens, Y. M. C. (2018). Direct oral anticoagulants: When to consider laboratory testing?International Journal of Laboratory Hematology, 40(S1), 30-33. https://doi.org/10.1111/ijlh.12816
    • De Maertelaere, E., Castoldi, E., Van Haute, I., Deeren, D., & Devreese, K. M. (2018). The interaction of factor V and tissue factor pathway inhibitor in a myeloma patient with acquired factor V deficiency. Haemophilia, 24(3), E160-E163. https://doi.org/10.1111/hae.13492
    • Hilderink, J. M., van der Linden, N., Kimenai, D. M., Litjens, E. J. R., Klinkenberg, L. J. J., Aref, B. M., Aziz, F., Kooman, J. P., Rennenberg, R. J. M. W., Bekers, O., Koopmans, R. P., & Meex, S. J. R. (2018). Biological Variation of Creatinine, Cystatin C, and eGFR over 24 Hours. Clinical Chemistry, 64(5), 851-860. https://doi.org/10.1373/clinchem.2017.282517
    • Streng, A., van der Linden, N., Kocken, J. M. M., Bekers, O., Bouwman, F., Mariman, E., Meex, S., Wodzig, W., & de Boer, D. (2018). Mass Spectrometric Identification of Cardiac Troponin T in Urine of Patients Suffering from Acute Myocardial Infarction. Journal of Applied Laboratory Medicine, 2(6), 857-867. https://doi.org/10.1373/jalm.2017.024224
    • Sabrkhany, S., Kuijpers, M. J. E., Knol, J. C., Damink, S. W. M. O., Dingemans, A.-M. C., Verheul, H. M., Piersma, S. R., Pham, T. V., Griffioen, A. W., Egbrink, M. G. A. O., & Jimenez, C. R. (2018). Exploration of the platelet proteome in patients with early-stage cancer. Journal of Proteomics, 177, 65-74. https://doi.org/10.1016/j.jprot.2018.02.011
    • Schurgers, L. J., Akbulut, A. C., Kaczor, D. M., Halder, M., Koenen, R. R., & Kramann, R. (2018). Initiation and Propagation of Vascular Calcification Is Regulated by a Concert of Platelet- and Smooth Muscle Cell-Derived Extracellular Vesicles. Frontiers in Cardiovascular Medicine, 5, Article 36. https://doi.org/10.3389/fcvm.2018.00036
    • Peeters, F. E. C. M., van Mourik, M. J. W., Meex, S. J. R., Bucerius, J., Schalla, S. M., Gerretsen, S. C., Mihl, C., Dweck, M. R., Schurgers, L. J., Wildberger, J. E., Crijns, H. J. G. M., & Kietselaer, B. L. J. H. (2018). Bicuspid Aortic Valve Stenosis and the Effect of Vitamin K2 on Calcification Using F-18-Sodium Fluoride Positron Emission Tomography/Magnetic Resonance: The BASIK2 Rationale and Trial Design. Nutrients, 10(4), Article 386. https://doi.org/10.3390/nu10040386
    • Panova-Noeva, M., Schulz, A., Arnold, N., Hermanns, M. I., Prochaska, J. H., Laubert-Reh, D., Spronk, H. M., Blettner, M., Beutel, M., Pfeiffer, N., Munzel, T., Lackner, K. J., ten Cate, H., & Wild, P. S. (2018). Coagulation and inflammation in long-term cancer survivors: results from the adult population. Journal of Thrombosis and Haemostasis, 16(4), 699-708. https://doi.org/10.1111/jth.13975
    • Mackman, N., Spronk, H. M. H., Stouffer, G. A., & ten Cate, H. (2018). Dual Anticoagulant and Antiplatelet Therapy for Coronary Artery Disease and Peripheral Artery Disease Patients. Arteriosclerosis Thrombosis and Vascular Biology, 38(4), 726-732. https://doi.org/10.1161/ATVBAHA.117.310048
    • Vajen, T., Heinzmann, A. C. A., Dickhout, A., Zhao, Z., Nagy, M., Heemskerk, J. W. M., & Koenen, R. R. (2018). Laminar Flow-based Assays to Investigate Leukocyte Recruitment on Cultured Vascular Cells and Adherent Platelets. Journal of visualized experiment, (134), Article e57009. https://doi.org/10.3791/57009
    • ten Cate-Hoek, N. J. (2018). Prevention and treatment of the post-thrombotic syndrome. Research and practice in thrombosis and haemostasis, 2(2), 209-219. https://doi.org/10.1002/rth2.12085
    • Nagler, M., ten Cate, H., Prins, M. H., & ten Cate-Hoek, A. J. (2018). Risk factors for recurrence in deep vein thrombosis patients following a tailored anticoagulant treatment incorporating residual vein obstruction. Research and practice in thrombosis and haemostasis, 2(2), 299-309. https://doi.org/10.1002/rth2.12079
    • Olie, R. H., van der Meijden, P. E. J., & ten Cate, H. (2018). The coagulation system in atherothrombosis: Implications for new therapeutic strategies. Research and practice in thrombosis and haemostasis, 2(2), 188-198. https://doi.org/10.1002/rth2.12080
    • Borst, O., Munzer, P., Alnaggar, N., Geue, S., Tegtmeyer, R., Rath, D., Droppa, M., Seizer, P., Heitmeier, S., Heemskerk, J. W. M., Jennings, L. K., Storey, R. F., Angiolillo, D. J., Rocca, B., Spronk, H., Ten Cate, H., Gawaz, M., & Geisler, T. (2018). Inhibitory mechanisms of very low-dose rivaroxaban in non-ST-elevation myocardial infarction. Blood advances, 2(6), 715-730. https://doi.org/10.1182/bloodadvances.2017013573
    • de Brouwer, B., Drent, M., van den Ouweland, J. M. W., Wijnen, P. A., van Moorsel, C. H. M., Bekers, O., Grutters, J. C., White, E. S., & Janssen, R. (2018). Increased circulating desmosine and age-dependent elastinolysis in idiopathic pulmonary fibrosis. Respiratory Research, 19(1), Article 45. https://doi.org/10.1186/s12931-018-0747-6
    • Miller, M. C., Ludwig, A.-K., Wichapong, K., Kaltner, H., Kopitz, J., Gabius, H.-J., & Mayo, K. H. (2018). Adhesion/growth-regulatory galectins tested in combination: evidence for formation of hybrids as heterodimers. Biochemical Journal, 475(5), 1003-1018. https://doi.org/10.1042/BCJ20170658
    • Mori, J., Nagy, Z., Di Nunzio, G., Smith, C. W., Geer, M. J., Al Ghaithi, R., van Geffen, J. P., Heising, S., Boothman, L., Tullemans, B. M. E., Correia, J. N., Tee, L., Kuijpers, M. J. E., Harrison, P., Heemskerk, J. W. M., Jarvis, G. E., Tarakhovsky, A., Weiss, A., Mazharian, A., & Senis, Y. A. (2018). Maintenance of murine platelet homeostasis by the kinase Csk and phosphatase CD148. Blood, 131(10), 1122-1144. https://doi.org/10.1182/blood-2017-02-768077
    • de Lange, N., Schol, P., Lance, M., Woiski, M., Langenveld, J., Rijnders, R., Smits, L., Wassen, M., Henskens, Y., & Scheepers, H. (2018). Restrictive Versus Massive Fluid Resuscitation Strategy (REFILL study), influence on blood loss and hemostatic parameters in obstetric hemorrhage: study protocol for a randomized controlled trial. Trials, 19(1), Article 166. https://doi.org/10.1186/s13063-018-2512-z
    • Silva, C. T., Zorkoltseva, I. V., Niemeijer, M. N., van den Berg, M. E., Amin, N., Demirkan, A., van Leeuwen, E., Iglesias, A. I., Pineros-Hernandez, L. B., Restrepo, C. M., Kors, J. A., Kirichenko, A. V., Willemsen, R., Oostra, B. A., Stricker, B. H., Uitterlinden, A. G., Axenovich, T. I., van Duijn, C. M., & Isaacs, A. (2018). A combined linkage, microarray and exome analysis suggests MAP3K11 as a candidate gene for left ventricular hypertrophy. BMC Medical Genomics, 11(1), Article 22. https://doi.org/10.1186/s12920-018-0339-9
    • Ruhle, F., & Stoll, M. (2018). Advances in predicting venous thromboembolism risk in children. British Journal of Haematology, 180(5), 654-665. https://doi.org/10.1111/bjh.15060
    • Seyerle, A. A., Sitlani, C. M., Noordam, R., Gogarten, S. M., Li, J., Li, X., Evans, D. S., Sun, F., Laaksonen, M. A., Isaacs, A., Kristiansson, K., Highland, H. M., Stewart, J. D., Harris, T. B., Trompet, S., Bis, J. C., Peloso, G. M., Brody, J. A., Broer, L., ... Avery, C. L. (2018). Pharmacogenomics study of thiazide diuretics and QT interval in multi-ethnic populations: the cohorts for heart and aging research in genomic epidemiology. Pharmacogenomics Journal, 18(2), 215-226. https://doi.org/10.1038/tpj.2017.10
    • Kuiper, G. J. A. J. M., Christiaans, M. H. L., Mullens, M. H. J. . M., ten Cate, H., Hamulyak, K., & Henskens, Y. M. C. (2018). Routine haemostasis testing before transplanted kidney biopsy: a cohort study. Transplant International, 31(3), 302-312. https://doi.org/10.1111/tri.13090
    • Thomassen, S., Mastenbroek, T. G., Swieringa, F., Winckers, K., Feijge, M. A. H., Schrijver, R., Cosemans, J. M. E. M., Maroney, S. A., Mast, A. E., Hackeng, T. M., & Heemskerk, J. W. M. (2018). Suppressive Role of Tissue Factor Pathway Inhibitor-alpha in Platelet-Dependent Fibrin Formation under Flow Is Restricted to Low Procoagulant Strength. Thrombosis and Haemostasis, 118(3), 502-513. https://doi.org/10.1055/s-0038-1627453
    • El Morabet, N., Uitvlugt, E. B., van den Bemt, B. J. F., van den Bemt, P. M. L. A., Janssen, M. J. A., & Karapinar-Carkit, F. (2018). Prevalence and Preventability of Drug-Related Hospital Readmissions: A Systematic Review. Journal of the American Geriatrics Society, 66(3), 602-608. https://doi.org/10.1111/jgs.15244
    • Nagy, M., Mastenbroek, T. G., Mattheij, N. J. A., de Witt, S., Clemetson, K. J., Kirschner, J., Schulz, A. S., Vraetz, T., Speckmann, C., Braun, A., Cosemans, J. M. E. M., Zieger, B., & Heemskerk, J. W. M. (2018). Variable impairment of platelet functions in patients with severe, genetically linked immune deficiencies. Haematologica-the Hematology Journal, 103(3), 540-549. https://doi.org/10.3324/haematol.2017.176974
    • Seijkens, T. T. P., van Tiel, C. M., Kusters, P. J. H., Atzler, D., Soehnlein, O., Zarzycka, B., Aarts, S. A. B. M., Lameijer, M., Gijbels, M. J., Beckers, L., den Toom, M., Slutter, B., Kuiper, J., Duchene, J., Aslani, M., Megens, R. T. A., van 't Veer, C., Kooij, G., Schrijver, R., ... Lutgens, E. (2018). Targeting CD40-Induced TRAF6 Signaling in Macrophages Reduces Atherosclerosis. Journal of the American College of Cardiology, 71(5), 527-542. https://doi.org/10.1016/j.jacc.2017.11.055
    • Spronk, H. M. H., Padro, T., Siland, J. E., Prochaska, J. H., Winters, J., van der Wal, A. C., Posthuma, J. J., Lowe, G., d'Alessandro, E., Wenzel, P., Coenen, D. M., Reitsma, P. H., Ruf, W., van Gorp, R. H., Koenen, R. R., Vajen, T., Alshaikh, N. A., Wolberg, A. S., Macrae, F. L., ... ten Cate, H. (2018). Atherothrombosis and Thromboembolism: Position Paper from the Second Maastricht Consensus Conference on Thrombosis. Thrombosis and Haemostasis, 118(2), 229-250. https://doi.org/10.1160/TH17-07-0492
    • Cosemans, J. M. E. M. (2018). At the MERcy of platelet primers. Journal of Thrombosis and Haemostasis, 16(2), 349-351. https://doi.org/10.1111/jth.13915
    • Henskens, Y. M. C., Gulpen, A. J. W., van Oerle, R., Wetzels, R., Verhezen, P., Spronk, H., Schalla, S., Crijns, H. J., ten Cate, H., & ten Cate-Hoek, A. (2018). Detecting clinically relevant rivaroxaban or dabigatran levels by routine coagulation tests or thromboelastography in a cohort of patients with atrial fibrillation. Thrombosis Journal, 16(1), Article 3. https://doi.org/10.1186/s12959-017-0160-2
    • Douxfils, J., Ageno, W., Samama, C. .-M., Lessire, S., ten Cate, H., Verhamme, P., Dogne, J. .-M., & Mullier, F. (2018). Laboratory testing in patients treated with direct oral anticoagulants: a practical guide for clinicians. Journal of Thrombosis and Haemostasis, 16(2), 209-219. https://doi.org/10.1111/jth.13912
    • Yousefi, S., Abbassi-Daloii, T., Kraaijenbrink, T., Vermaat, M., Mei, H., van't Hof, P., van Iterson, M., Zhernakova, D. V., Claringbould, A., Franke, L., 't Hart, L. M., Slieker, R. C., van der Heijden, A., de Knijff, P., 't Hoen, P. A. C., BIOS Consortium, Jansen, R., van Meurs, J., Heijmans, B. T., ... Franke, L. (2018). A SNP panel for identification of DNA and RNA specimens. BMC Genomics, 19(90), Article 90. https://doi.org/10.1186/s12864-018-4482-7
    • Quaranta, R., Fell, J., Ruhle, F., Rao, J., Piccini, I., Arauzo-Brave, M. J., Verkerk, A. O., Stoll, M., & Greber, B. (2018). Revised roles of ISL1 in a hES cell-based model of human heart chamber specification. Elife, 7, Article e31706. https://doi.org/10.7554/eLife.31706
    • Brekelmans, M. P. A., Abdoellakhan, R. A., Scheres, L. J. J., Biedermann, J. S., Hutten, B. A., Meijer, K., ten Cate, H., Huisman, M., Kruip, M. J. H. A., Middeldorp, S., & Coppens, M. (2018). Clinical outcome of patients with a vitamin K antagonist-associated bleeding treated with prothrombin complex concentrate. Research and practice in thrombosis and haemostasis, 2(1), 77-84. https://doi.org/10.1002/rth2.12055
    • Bihlmeyer, N. A., Brody, J. A., Smith, A. V., Warren, H. R., Lin, H., Isaacs, A., Liu, C.-T., Marten, J., Radmanesh, F., Hall, L. M., Grarup, N., Mei, H., Muller-Nurasyid, M., Huffman, J. E., Verweij, N., Guo, X., Yao, J., Li-Gao, R., van den Berg, M., ... Sotoodehnia, N. (2018). ExomeChip-Wide Analysis of 95 626 Individuals Identifies 10 Novel Loci Associated With QT and JT Intervals. Circulation : Cardiovascular Genetics, 11(1), Article e001758. https://doi.org/10.1161/CIRCGEN.117.001758
    • ten Cate-Hoek, A. J., Amin, E. E., Bouman, A. C., Meijer, K., Tick, L. W., Middeldorp, S., Mostard, G. J. M., ten Wolde, M., van den Heiligenberg, S. M., van Wissen, S., van de Poel, M. H. W., Villalta, S., Serne, E. H., Otten, H.-M., Klappe, E. H., Bistervels, I. M., Lauw, M. N., Piersma-Wichers, M., Prandoni, P., ... IDEAL DVT Investigators (2018). Individualised versus standard duration of elastic compression therapy for prevention of post-thrombotic syndrome (IDEAL DVT): a multicentre, randomised, single-blind, allocation-concealed, non-inferiority trial. The Lancet Haematology, 5(1), 25-33. https://doi.org/10.1016/S2352-3026(17)30227-2