• 2019
    • Gulpen, A. J. W., ten Cate, H., Henskens, Y. M. C., van Oerle, R., Wetzels, R., Schalla, S., Crijns, H. J., & ten Cate-Hoek, A. J. (2019). The daily practice of direct oral anticoagulant use in patients with atrial fibrillation; an observational cohort study. PLOS ONE, 14(6), Article 0217302. https://doi.org/10.1371/journal.pone.0217302
    • Jooss, N. J., De Simone, I., Provenzale, I., Fernández, D. I., Brouns, S. L. N., Farndale, R. W., Henskens, Y. M. C., Kuijpers, M. J. E., Ten Cate, H., van der Meijden, P. E. J., Cavill, R., & Heemskerk, J. W. M. (2019). Role of Platelet Glycoprotein VI and Tyrosine Kinase Syk in Thrombus Formation on Collagen-Like Surfaces. International journal of molecular sciences, 20(11), Article 2788. https://doi.org/10.3390/ijms20112788
    • Gomes, C. P. D. C., Agg, B., Andova, A., Arslan, S., Baker, A., Bartekova, M., Beis, D., Betsou, F., Wettinger, S. B., Bugarski, B., Condorelli, G., da Silva, G. J. J., Danilin, S., de Gonzalo-Calvo, D., Buil, A., Carmo-Fonseca, M., Enguita, F. J., Felekkis, K., Ferdinandy, P., ... Devaux, Y. (2019). Catalyzing Transcriptomics Research in Cardiovascular Disease: The CardioRNA COST Action CA17129. Non-coding RNA research, 5(2), Article 31. https://doi.org/10.3390/ncrna5020031
    • van Setten, J., Verweij, N., Mbarek, H., Niemeijer, M. N., Trompet, S., Arking, D. E., Brody, J. A., Gandin, I., Grarup, N., Hall, L. M., Hemerich, D., Lyytikainen, L.-P., Mei, H., Mueller-Nurasyid, M., Prins, B. P., Robino, A., Smith, A. V., Warren, H. R., Asselbergs, F. W., ... Isaacs, A. (2019). Genome-wide association meta-analysis of 30,000 samples identifies seven novel loci for quantitative ECG traits. European Journal of Human Genetics, 27(6), 952-962. https://doi.org/10.1038/s41431-018-0295-z
    • van Geffen, A., Brouns, S., Batista, J., McKinney, H., Kempster, C., Nagy, M., Sivapalaratnam, S., Baaten, C., Bourry, N., Frontini, M., Jurk, K., Krause, M., Pilliteri, D., Swieringa, F., Verdoold, R., Cavill, R., Kuijpers, M., Ouwehand, W. H., Downes, K., & Heemskerk, J. (2019). High-throughput elucidation of thrombus formation reveals sources of platelet function variability. Haematologica-the Hematology Journal, 104(6), 1256-1267. https://doi.org/10.3324/haematol.2018.198853
    • ten Cate, H., Kontny, F., & Nilsen, D. W. (2019). Editorial: Novel and potential markers for prediction of outcome in patients with acute and chronic coronary heart disease. Frontiers in Cardiovascular Medicine, 6, 1-3. Article 66. https://doi.org/10.3389/fcvm.2019.00066
    • Silvestre-Roig, C., Braster, Q., Wichapong, K., Lee, E. Y., Marie Teulon, J., Berrebeh, N., Winter, J., Adrover, J. M., Santos, G. S., Froese, A., Lemnitzer, P., Ortega-Gomez, A., Chevre, R., Marschner, J., Schumski, A., Winter, C., Perez-Olivares, L., Pan, C., Paulin, N., ... Soehnlein, O. (2019). Externalized histone H4 orchestrates chronic inflammation by inducing lytic cell death. Nature, 569(7755), 236-240. https://doi.org/10.1038/s41586-019-1167-6
    • Heestermans, M., Salloum-Asfar, S., Streef, T., Laghmani, E. H., Salvatori, D., Luken, B. M., Zeerleder, S. S., Spronk, H. M. H., Korporaal, S. J., Kirchhofer, D., Wagenaar, G. T. M., Versteeg, H. H., Reitsma, P. H., Renne, T., & van Vlijmen, B. J. M. (2019). Mouse venous thrombosis upon silencing of anticoagulants depends on tissue factor and platelets, not FXII or neutrophils. Blood, 133(19), 2090-2099. https://doi.org/10.1182/blood-2018-06-853762
    • Klotz, L., Eschborn, M., Lindner, M., Liebmann, M., Herold, M., Janoschka, C., Garrido, B. T., Schulte-Mecklenbeck, A., Gross, C. C., Breuer, J., Hundehege, P., Posevitz, V., Pignolet, B., Nebel, G., Glander, S., Freise, N., Austermann, J., Wirth, T., Campbell, G. R., ... Wiendl, H. (2019). Teriflunomide treatment for multiple sclerosis modulates T cell mitochondrial respiration with affinity-dependent effects. Science Translational Medicine, 11(490), Article 5563. https://doi.org/10.1126/scitranslmed.aao5563
    • Wichapong, K., Poelman, H., Ercig, B., Hrdinova, J., Liu, X., Lutgens, E., & Nicolaes, G. A. F. (2019). Rational modulator design by exploitation of protein-protein complex structures. Future Medicinal Chemistry, 11(9), 1015-1033. https://doi.org/10.4155/fmc-2018-0433
    • Gurbel, P. A., Fox, K. A. A., Tantry, U. S., ten Cate, H., & Weitz, J. (2019). Combination Antiplatelet and Oral Anticoagulant Therapy in Patients With Coronary and Peripheral Artery Disease Focus on the COMPASS Trial. Circulation, 139(18), 2170-2185. https://doi.org/10.1161/CIRCULATIONAHA.118.033580
    • Lemkes, J. S., Janssens, G. N., van der Hoeven, N. W., Jewbali, L. S. D., Dubois, E. A., Meuwissen, M., Rijpstra, T. A., Bosker, H. A., Blans, M. J., Bleeker, G. B., Baak, R., Vlachojannis, G. J., Eikemans, B. J. W., van der Harst, P., van der Horst, I. C. C., Voskuil, M., van der Heijden, J. J., Beishuizen, A., Stoel, M., ... van Royen, N. (2019). Coronary Angiography after Cardiac Arrest without ST-Segment Elevation. New England Journal of Medicine, 380(15), 1397-1407. https://doi.org/10.1056/NEJMoa1816897
    • Streefkerk, D. E., Schmidt, M., Ippel, J. H., Hackeng, T. M., Nuijens, T., Timmerman, P., & van Maarseveen, J. H. (2019). Synthesis of Constrained Tetracyclic Peptides by Consecutive CEPS, CLIPS, and Oxime Ligation. Organic Letters, 21(7), 2095-2100. https://doi.org/10.1021/acs.orglett.9b00378
    • Slater, A., Perrella, G., Onselaer, M.-B., Martin, E. M., Gauer, J. S., Xu, R.-G., Heemskerk, J. W. M., Ariens, R. A. S., & Watson, S. P. (2019). Does fibrin(ogen) bind to monomeric or dimeric GPVI, or not at all?Platelets, 30(3), 281-289. https://doi.org/10.1080/09537104.2018.1508649
    • Kremers, B. M. M., Birocchi, S., van Oerle, R., Zeerleder, S., Spronk, H. M. H., Mees, B. M. E., Luken, B. M., ten Cate, H., & ten Cate-Hoek, A. J. (2019). Searching for a Common Thrombo-Inflammatory Basis in Patients With Deep Vein Thrombosis or Peripheral Artery Disease. Frontiers in Cardiovascular Medicine, 6, 1-11. Article 33. https://doi.org/10.3389/fcvm.2019.00033
    • Panova-Noeva, M., Neu, M. A., Eckerle, S., Spix, C., Schneider, A., Schmidtmann, I., Spronk, H. M., Pfeiffer, N., Beutel, M., Lackner, K. J., Muenzel, T., ten Cate, H., Merzenich, H., Faber, J., & Wild, P. S. (2019). Cardiovascular risk factors are important determinants of platelet-dependent thrombin generation in adult survivors of childhood cancer. Clinical research in cardiology, 108(4), 438-447. https://doi.org/10.1007/s00392-018-1374-4
    • Noels, H., Weber, C., & Koenen, R. R. (2019). Chemokines as Therapeutic Targets in Cardiovascular Disease The Road Behind, The Road Ahead. Arteriosclerosis Thrombosis and Vascular Biology, 39(4), 583-592. https://doi.org/10.1161/ATVBAHA.118.312037
    • Henriquez, D. D. C. A., Bloemenkamp, K. W. M., Loeff, R. M., Zwart, J. J., van Roosmalen, J. J. M., Zwaginga, J. J., van der Bom, J. G., Adriaanse, H. J., van den Akker, E. S. A., Baas, M. I., Bank, C. M. C., van Beek, E., de Boer, B. A., de Boer, K., van der Borden, D. M. R., Bremer, H. A., Brons, J. T. J., Burggraaff, J. M., Ceelie, H., ... TeMpOH-1 study group (2019). Fluid resuscitation during persistent postpartum haemorrhage and maternal outcome: A nationwide cohort study. European Journal of Obstetrics & Gynecology and Reproductive Biology, 235, 49-56. https://doi.org/10.1016/j.ejogrb.2019.01.027
    • Posthuma, J. J., Posma, J. J. N., Schep, G., Bender, M. M. H., van Oerle, R., van der Wal, A. C., Ten Cate, H., & Spronk, H. M. H. (2019). Protease-activated receptors are potential regulators in the development of arterial endofibrosis in high-performance athletes. Journal of Vascular Surgery, 69(4), 1243-1250. https://doi.org/10.1016/j.jvs.2018.05.220
    • Brouwers, M. C. G. J., Simons, N., Stehouwer, C. D. A., Koek, G. H., Schaper, N. C., & Isaacs, A. (2019). Relationship Between Nonalcoholic Fatty Liver Disease Susceptibility Genes and Coronary Artery Disease. Hepatology communications, 3(4), 587-596. https://doi.org/10.1002/hep4.1319
    • Daliri, S., Bekker, C. L., Buurman, B. M., Reimer, W. J. M. S. O., van den Bemt, B. J. F., & Karapinar-Carkit, F. (2019). Barriers and facilitators with medication use during the transition from hospital to home: a qualitative study among patients. BMC Health Services Research, 19(1), Article 204. https://doi.org/10.1186/s12913-019-4028-y
    • Schulz, A., Mueller, N. V., van de Lest, N. A., Eisenreich, A., Schmidbauer, M., Barysenka, A., Purfuerst, B., Sporbert, A., Lorenzen, T., Meyer, A. M., Herlan, L., Witten, A., Ruehle, F., Zhou, W., de Heer, E., Scharpfenecker, M., Panakova, D., Stoll, M., & Kreutz, R. (2019). Analysis of the genomic architecture of a complex trait locus in hypertensive rat models links Tmem63c to kidney damage. Elife, 8, Article 42068. https://doi.org/10.7554/eLife.42068
    • Daliri, S., Hugtenburg, J. G., ter Riet, G., van den Bemt, B. J. F., Buurman, B. M., op Reimer, W. J. M. S., van Buul-Gast, M.-C., & Karapinar-Carkit, F. (2019). The effect of a pharmacy-led transitional care program on medication-related problems post-discharge: A before-After prospective study. PLOS ONE, 14(3), Article 0213593. https://doi.org/10.1371/journal.pone.0213593
    • Krekels, J. P. M., Verhezen, P. W. M., & Henskens, Y. M. C. (2019). Platelet Aggregation in Healthy Participants is Not Affected by Smoking, Drinking Coffee, Consuming a High-Fat Meal, or Performing Physical Exercise. Clinical and Applied Thrombosis-Hemostasis, 25, 1-9. Article 1076029618782445. https://doi.org/10.1177/1076029618782445
    • Posthuma, J. J., Posma, J. J. N., van Oerle, R., Leenders, P., van Gorp, R. H., Jaminon, A. M. G., Mackman, N., Heitmeier, S., Schurgers, L. J., ten Cate, H., & Spronk, H. M. H. (2019). Targeting Coagulation Factor Xa Promotes Regression of Advanced Atherosclerosis in Apolipoprotein-E Deficient Mice. Scientific Reports, 9(1), Article 3909. https://doi.org/10.1038/s41598-019-40602-w
    • Ibrahim-Kosta, M., Suchon, P., Couturaud, F., Smadja, D., Olaso, R., Germain, M., Saut, N., Goumidi, L., Derbois, C., Thibord, F., Debette, S., Amouyel, P., Deleuze, J. F., van Doorn, P., Castoldi, E., Patin, E., Alessi, M. C., Tregouet, D. A., & Morange, P. E. (2019). Minor allele of the factor V K858R variant protects from venous thrombosis only in non-carriers of factor V Leiden mutation. Scientific Reports, 9(1), Article 3750. https://doi.org/10.1038/s41598-019-40172-x
    • Wijnen, P., Drent, M., Bekers, O., Verschakelen, J., & Bast, A. (2019). VKORC1 and CYP2C9 Polymorphisms: A Case Report in a Dutch Family with Pulmonary Fibrosis. International journal of molecular sciences, 20(5), Article 1160. https://doi.org/10.3390/ijms20051160
    • Vroemen, W. H. M., Mezger, S. T. P., Masotti, S., Clerico, A., Bekers, O., de Boer, D., & Mingels, A. (2019). Cardiac Troponin T: Only Small Molecules in Recreational Runners After Marathon Completion. Journal of Applied Laboratory Medicine, 3(5), 909-911. https://doi.org/10.1373/jalm.2018.027144
    • Gandhi, S., Ruehle, F., & Stoll, M. (2019). Evolutionary Patterns of Non-Coding RNA in Cardiovascular Biology. Non-coding RNA, 5(1), Article 15. https://doi.org/10.3390/ncrna5010015
    • van der Meijden, P. E. J., & Heemskerk, J. W. M. (2019). Platelet biology and functions: new concepts and clinical perspectives. Nature Reviews Cardiology, 16(3), 166-179. https://doi.org/10.1038/s41569-018-0110-0
    • Donkel, S. J., Benaddi, B., Dippel, D. W. J., ten Cate, H., & de Maat, M. P. M. (2019). Prognostic Hemostasis Biomarkers in Acute Ischemic Stroke: A Systematic Review. Arteriosclerosis Thrombosis and Vascular Biology, 39(3), 360-372. https://doi.org/10.1161/ATVBAHA.118.312102
    • Shvetsova, E., Sofronova, A., Monajemi, R., Gagalova, K., Draisma, H. H. M., White, S. J., Santen, G. W. E., Lopes, S. M. C. D. S., Heijmans, B. T., van Meurs, J., Jansen, R., Franke, L., Kielbasa, S. M., den Dunnen, J. T., 't Hoen, P. A. C., Boomsma, D. I., Pool, R., van Dongen, J., Hottenga, J. J., ... GoNL consortium (2019). Skewed X-inactivation is common in the general female population. European Journal of Human Genetics, 27(3), 455-465. https://doi.org/10.1038/s41431-018-0291-3
    • Denisov, S. S., Ippel, J. H., Mans, B. J., Dijkgraaf, I., & Hackeng, T. M. (2019). SecScan: a general approach for mapping disulfide bonds in synthetic and recombinant peptides and proteins. Chemical Communications, 55(10), 1374-1377. https://doi.org/10.1039/c8cc08777f
    • Koenen, R. R. (2019). No hearty reception: infusion of CXCL4 impedes tissue repair by macrophages after myocardial infarction. Cardiovascular Research, 115(2), 264-265. https://doi.org/10.1093/cvr/cvy241
    • Vries, M. J. A., Macrae, F., Nelemans, P. J., Kuiper, G. J. A. J. M., Wetzels, R. J. H., Bowman, P., Verhezen, P. W. M., ten Cate, H., Ariens, R. A. S., & Henskens, Y. M. C. (2019). Assessment and determinants of whole blood and plasma fibrinolysis in patients with mild bleeding symptoms. Thrombosis Research, 174, 88-94. https://doi.org/10.1016/j.thromres.2018.12.004
    • Sabrkhany, S., Kuijpers, M. J. E., Griffioen, A. W., & Egbrink, M. G. A. O. (2019). Platelets: the holy grail in cancer blood biomarker research?Angiogenesis, 22(1), 1-2. https://doi.org/10.1007/s10456-018-9651-4
    • Kuiper, G. J. A. J. M., van Egmond, L. T., Henskens, Y. M. C., Roekaerts, P. M., Maessen, J. G., ten Cate, H., Buhre, W. F., & Lance, M. D. (2019). Shifts of Transfusion Demand in Cardiac Surgery After Implementation of Rotational Thromboelastometry-Guided Transfusion Protocols: Analysis of the HEROES-CS (HEmostasis Registry of patiEntS in Cardiac Surgery) Observational, Prospective Open Cohort Database. Journal of Cardiothoracic and Vascular Anesthesia, 33(2), 307-317. https://doi.org/10.1053/j.jvca.2018.08.203
    • Seijkens, T. T. P., Poels, K., Meiler, S., van Tiel, C. M., Kusters, P. J. H., Reiche, M., Atzler, D., Winkels, H., Tjwa, M., Poelman, H., Slutter, B., Kuiper, J., Gijbels, M., Kuivenhoven, J. A., Matic, L. P., Paulsson-Berne, G., Hedin, U., Hansson, G. K., Nicolaes, G. A. F., ... Lutgens, E. (2019). Deficiency of the T cell regulator Casitas B-cell lymphoma-B aggravates atherosclerosis by inducing CD8(+) T cell-mediated macrophage death. European Heart Journal, 40(4), 372-382. https://doi.org/10.1093/eurheartj/ehy714
    • Grottke, O., van Ryn, J., Zentai, C., Gan, G., Honickel, M., Rossaint, R., Ten Cate, H., & Spronk, H. M. H. (2019). Volume replacement strategies do not impair the binding of dabigatran to idarucizumab: Porcine model of hemodilution. PLOS ONE, 14(1), e0209350. Article 0209350. https://doi.org/10.1371/journal.pone.0209350
    • Moenen, F. C. J., Vries, M. J. A., Nelemans, P. J., van Rooy, K. J. M., Vranken, J. R. R. A., Verhezen, P. W. M., Wetzels, R. J. H., ten Cate, H., Schouten, H. C., Beckers, E. A. M., & Henskens, Y. M. C. (2019). Screening for platelet function disorders with Multiplate and platelet function analyzer. Platelets, 30(1), 81-87. https://doi.org/10.1080/09537104.2017.1371290
    • Benedikter, B. J., Bouwman, F. G., Heinzmann, A. C. A., Vajen, T., Mariman, E. C., Wouters, E. F. M., Savelkoul, P. H. M., Koenen, R. R., Rohde, G. G. U., van Oerle, R., Spronk, H. M., & Stassen, F. R. M. (2019). Proteomic analysis reveals procoagulant properties of cigarette smoke-induced extracellular vesicles. Journal of Extracellular Vesicles, 8(1), Article 1585163. https://doi.org/10.1080/20013078.2019.1585163
    • Peeters, F. E. C. M., Kietselaer, B. L. J. H., Hilderink, J., van der Linden, N., Niens, M., Crijns, H. J. G. M., & Meex, S. J. R. (2019). Biological variation of cardiac markers in patients with aortic valve stenosis. Open Heart, 6(1), Article 001040. https://doi.org/10.1136/openhrt-2019-001040
    • Luijten, J., van Greevenbroek, M. M. J., Schaper, N. C., Meex, S. J. R., van der Steen, C., Meijer, L. J., de Boer, D., de Graaf, J., Stehouwer, C. D. A., & Brouwers, M. C. G. J. (2019). Incidence of cardiovascular disease in familial combined hyperlipidemia: A 15-year follow-up study. Atherosclerosis, 280, 1-6. https://doi.org/10.1016/j.atherosclerosis.2018.11.013
    • Leader, A., Ten Cate, V., Ten Cate-Hoek, A. J., Spectre, G., Beckers, E. A. M., Raanani, P., Giaccherini, C., Pereg, D., Schouten, H. C., Falanga, A., & Ten Cate, H. (2019). Managing Anti-Platelet Therapy in Thrombocytopaenic Patients with Haematological Malignancy: A Multinational Clinical Vignette-Based Experiment. Thrombosis and Haemostasis, 119(1), 163-174. https://doi.org/10.1055/s-0038-1676520
    • Meani, P., Delnoij, T., Raffa, G. M., Morici, N., Viola, G., Sacco, A., Oliva, F., Heuts, S., Sels, J.-W., Driessen, R., Roekaerts, P., Gilbers, M., Bidar, E., Schreurs, R., Natour, E., Veenstra, L., Kats, S., Maessen, J., & Lorusso, R. (2019). Protracted aortic valve closure during peripheral veno-arterial extracorporeal life support: is intra-aortic balloon pump an effective solution?Perfusion, 34(1), 35-41. https://doi.org/10.1177/0267659118787426
    • Posma, J. J., Grover, S. P., Hisada, Y., Owens, A. P., Antoniak, S., Spronk, H. M., & Mackman, N. (2019). Roles of Coagulation Proteases and PARs (Protease-Activated Receptors) in Mouse Models of Inflammatory Diseases. Arteriosclerosis Thrombosis and Vascular Biology, 39(1), 13-24. https://doi.org/10.1161/ATVBAHA.118.311655
    • Bucerius, J., Dijkgraaf, I., Mottaghy, F. M., & Schurgers, L. J. (2019). Target identification for the diagnosis and intervention of vulnerable atherosclerotic plaques beyond 18F-fluorodeoxyglucose positron emission tomography imaging: promising tracers on the horizon. European Journal of Nuclear Medicine and Molecular Imaging, 46(1), 251-265. https://doi.org/10.1007/s00259-018-4176-z
    • Ratzon, R., Tamir, S., Friehmann, T., Livneh, N., Dudnik, E., Rozental, A., Hamburger-Avnery, O., Pereg, D., Derazne, E., Brenner, B., Raanani, P., ten Cate, H., Spectre, G., & Leader, A. (2019). Thrombosis, anticoagulation and outcomes in malignant superior vena cava syndrome. Journal of Thrombosis and Thrombolysis, 47(1), 121-128. https://doi.org/10.1007/s11239-018-1747-6
    • Kaufmann, T., Forte, J. C., Hiemstra, B., Wiering, M. A., Grzegorczyk, M., Epema, A. H., van der Horst, I. C. C., & SICS Study Group (2019). A Bayesian Network Analysis of the Diagnostic Process and its Accuracy to Determine How Clinicians Estimate Cardiac Function in Critically Ill Patients: Prospective Observational Cohort Study. JMIR Medical Informatics, 7(4), 214-224. Article 15358. https://doi.org/10.2196/15358
    • Davey, N. E., Babu, M. M., Blackledge, M., Bridge, A., Capella-Gutierrez, S., Dosztanyi, Z., Drysdale, R., Edwards, R. J., Elofsson, A., Felli, I. C., Gibson, T. J., Gutmanas, A., Hancock, J. M., Harrow, J., Higgins, D., Jeffries, C. M., Le Mercier, P., Mészáros, B., Necci, M., ... Tosatto, S. C. E. (2019). An intrinsically disordered proteins community for elixir [version 1; peer review: 2 approved]. F1000Research, 8, 1-19. https://doi.org/10.12688/f1000research.20136.1