Geert-Jan Kuiper

Post doc

Gerhardus Johannes Albert Josef Maria (Geert-Jan) Kuiper completed his medical degree in 2010 at the Faculty of Health, Medicine and Life Sciences of Maastricht University, the Netherlands. In his last year of Medicine he was already involved in thrombosis and haemostasis research under the supervision of Dr Marcus D. Lancé. After finishing his medical degree, he was appointed a research position at the Laboratory of Clinical Thrombosis and Haemostasis of Prof. Hugo ten Cate at CARIM. In December of 2012 he started his anaesthesiology residency at the Maastricht UMC+ ending in November of 2017. During his anaesthesiology training he continued to do research on thrombosis and haemostasis. On 31 May 2018 this resulted in a successful defence of his PhD thesis titled: Haemostasis monitoring: pinpointing using point-of-care. From July 2018 till June 2020 he followed two fellowships in advanced clinical practice and in cardiovascular anaesthesia at the Toronto General Hospital, Toronto, Canada. As of August 2020 he is working again at Maastricht UMC+ as a consultant anaesthesiologist and researcher with focus on thrombosis and haemostasis research.

Current research:

  • Point-Of-Care monitoring with novel devices in acute hemostatic disbalance
  • Multicenter studies on periprocedural DOAC reversal in clinical bleeding
  • Monitoring and transfusion strategies in patient blood management
  • Multicenter studies on perioperative ventilation practice
  • Academic Editor at Medicine (Online ISSN: 1536-5964)

Department of Anesthesiology and Pain Treatment
P. Debyelaan 25, 6229HX, Maastricht
Room number: 4.E1.012
T: +31(0)43 387 73 95

  • 2024
    • Willers, V., Krumeich, J. R. L., Hulshof, A.-M., Buise, M. P., van der Horst, I. C. C., Henskens, Y. M. C., van Bussel, B. C. T., & Kuiper, G. J. A. J. M. (2024). Comparison of the Quantra QPlus and ROTEM Goal-Directed Transfusion Protocols in Cardiothoracic Surgery Patients: A Prospective Observational Study. Journal of Cardiothoracic and Vascular Anesthesia, 38(11), 2559-2566. https://doi.org/10.1053/j.jvca.2024.07.046
  • 2023
    • Heuts, S., Ceulemans, A., Kuiper, G. J. A. J. M., Schreiber, J. U., van Varik, B. J., Olie, R. H., Ten Cate, H., Maessen, J. G., Milojevic, M., & Maesen, B. (2023). Optimal management of cardiac surgery patients using direct oral anticoagulants: recommendations for clinical practice. European Journal of Cardio-Thoracic Surgery, 64(4), Article ezad340. https://doi.org/10.1093/ejcts/ezad340
    • Schultinge, L., Hulshof, A. M., van Neerven, D., Mulder, M. M. G., Sels, J. W. E. M., Hulsewe, H. P. M. G., Kuiper, G. J. A. J. M., Olie, R. H., ten Cate, H., van der Horst, I. C. C., van Bussel, B. C. T., & Henskens, Y. M. C. (2023). Applications of rotational thromboelastometry in heparin monitoring in critical COVID-19 disease: Observations in the Maastricht Intensive Care COVID cohort. Thrombosis Update, 12(1), Article 100140. https://doi.org/10.1016/j.tru.2023.100140
  • 2021
    • Ho, L. T. S., McVey, M. J., Kuiper, G. J. A. J. M., Gross, P. L., & Karkouti, K. (2021). Analysis of the effect of varying protamine-to-heparin ratio on coagulation in vitro. British Journal of Anaesthesia, 127(4), E128-E130. https://doi.org/10.1016/j.bja.2021.06.037
    • Hulshof, A. M., Braeken, D. C. W., Ghossein-Doha, C., van Santen, S., Sels, J. W. E. M., Kuiper, G. J. A. J. M., van der Horst, I. C. C., ten Cate, H., van Bussel, B. C. T., Olie, R. H., & Henskens, Y. M. C. (2021). Hemostasis and fibrinolysis in COVID-19 survivors 6 months after intensive care unit discharge. Research and practice in thrombosis and haemostasis, 5(6), Article e12579. https://doi.org/10.1002/rth2.12579
  • 2019
    • Vries, M. J. A., Macrae, F., Nelemans, P. J., Kuiper, G. J. A. J. M., Wetzels, R. J. H., Bowman, P., Verhezen, P. W. M., ten Cate, H., Ariens, R. A. S., & Henskens, Y. M. C. (2019). Assessment and determinants of whole blood and plasma fibrinolysis in patients with mild bleeding symptoms. Thrombosis Research, 174, 88-94. https://doi.org/10.1016/j.thromres.2018.12.004
    • Kuiper, G. J. A. J. M., van Egmond, L. T., Henskens, Y. M. C., Roekaerts, P. M., Maessen, J. G., ten Cate, H., Buhre, W. F., & Lance, M. D. (2019). Shifts of Transfusion Demand in Cardiac Surgery After Implementation of Rotational Thromboelastometry-Guided Transfusion Protocols: Analysis of the HEROES-CS (HEmostasis Registry of patiEntS in Cardiac Surgery) Observational, Prospective Open Cohort Database. Journal of Cardiothoracic and Vascular Anesthesia, 33(2), 307-317. https://doi.org/10.1053/j.jvca.2018.08.203
  • 2018
    • Vries, M. J., van der Meijden, P. E., Kuiper, G. J., Nelemans, P. J., Wetzels, R. J., van Oerle, R. G., Lance, M. D., ten Cate, H., & Henskens, Y. M. (2018). Preoperative screening for bleeding disorders: A comprehensive laboratory assessment of clinical practice. Research and practice in thrombosis and haemostasis, 2(4), 767-777. https://doi.org/10.1002/rth2.12114
    • Kuiper, G. J. A. J. M., Christiaans, M. H. L., Mullens, M. H. J. . M., ten Cate, H., Hamulyak, K., & Henskens, Y. M. C. (2018). Routine haemostasis testing before transplanted kidney biopsy: a cohort study. Transplant International, 31(3), 302-312. https://doi.org/10.1111/tri.13090
  • 2017
    • Kuiper, G. J. A. J. M., Houben, R., Wetzels, R. J. H., Verhezen, P. W. M., van Oerle, R., ten Cate, H., Henskens, Y. M. C., & Lance, M. D. (2017). The use of regression analysis in determining reference intervals for low hematocrit and thrombocyte count in multiple electrode aggregometry and platelet function analyzer 100 testing of platelet function. Platelets, 28(7), 668-675. https://doi.org/10.1080/09537104.2016.1257782
  • 2016
    • Kuiper, G. J. A. J. M., & Henskens, Y. M. C. (2016). Rapid and Correct Prediction of Thrombocytopenia and Hypofibrinogenemia with Rotational Thromboelastometry in Cardiac Surgery Reconsidered. Journal of Cardiothoracic and Vascular Anesthesia, 30(6), 55-56. https://doi.org/10.1053/j.jvca.2016.04.009
    • van Erning, F. N., Zanders, M. M., Kuiper, J. G., van Herk-Sukel, M. P., Maas, H. A., Vingerhoets, R. W., Zimmerman, D. D., de Feyter, E. P., van de Poll, M. E., & Lemmens, V. E. (2016). Drug dispensings among elderly in the year before colon cancer diagnosis versus matched cancer-free controls. Journal of Clinical Pharmacy and Therapeutics, 41(5), 538-545. https://doi.org/10.1111/jcpt.12434
    • Kuiper, G.-J., Kleinegris, M.-C., van Oerle, R., Spronk, H., Lance, M., ten Cate, H., & Henskens, Y. (2016). Validation of a modified thromboelastometry approach to detect changes in fibrinolytic activity. Thrombosis Journal, 14(1), Article 1. https://doi.org/10.1186/s12959-016-0076-2
    • van Poucke, S., Stevens, K., Wetzels, R., Kicken, C., Verhezen, P., Theunissen, M., Kuiper, G.-J., van Oerle, R., Henskens, Y., & Lance, M. (2016). Early platelet recovery following cardiac surgery with cardiopulmonary bypass. Platelets, 27(8), 751-757. https://doi.org/10.3109/09537104.2016.1173665
  • 2014
    • van IJzendoorn, M. C. O., Koopmans, M., Strauch, U., Heines, S., den Boer, S., Kors, B. M., van der Voort, P. H. J., Dennesen, P. J. W., van den Hul, I., Alberts, E., Egbers, P., Esteban, A., Frutos-Vivar, F., & Kuiper, M. A. (2014). Ventilator setting in ICUs: comparing a Dutch with a European cohort. Netherlands Journal of Medicine, 72(9), 473-480.
    • Olde Engberink, R. H. G., Kuiper, G. J. A. J. M., Wetzels, R. J. H., Nelemans, P. J., Lance, M. D., Beckers, E. A. M., & Henskens, Y. M. C. (2014). Rapid and Correct Prediction of Thrombocytopenia and Hypofibrinogenemia With Rotational Thromboelastometry in Cardiac Surgery. Journal of Cardiothoracic and Vascular Anesthesia, 28(2), 210-216. https://doi.org/10.1053/j.jvca.2013.12.004
    • Ninivaggi, M., Feijge, M. A. H., Baaten, C. C. F. M. J., Kuiper, G. J. A. J. M., Marcus, M. A. E., ten Cate, H., Lance, M. D., Heemskerk, J. W. M., & van der Meijden, P. E. J. (2014). Additive roles of platelets and fibrinogen in whole-blood fibrin clot formation upon dilution as assessed by thromboelastometry. Thrombosis and Haemostasis, 111(3), 447-457. https://doi.org/10.1160/TH13-06-0493
  • 2012
    • Lance, M. D., Kuiper, G. J. A. J. M., Sloep, M., Spronk, H. M. H., van Oerle, R., ten Cate, H., Marcus, M. A. E., & Henskens, Y. M. C. (2012). The effects of pneumatic tube system transport on ROTEM analysis and contact activation assessed by thrombin generation test. Thrombosis Research, 130(3), E147-E150. https://doi.org/10.1016/j.thromres.2012.05.002
    • Lance, M. D., Ninivaggi, M., Schols, S. E. M., Feijge, M. A. H., Oehrl, S. K., Kuiper, G. J. A. J. M., Nikiforou, M., Marcus, M. A. E., Hamulyak, K., van Pampus, E. C. M., ten Cate, H., & Heemskerk, J. W. M. (2012). Perioperative dilutional coagulopathy treated with fresh frozen plasma and fibrinogen concentrate: a prospective randomized intervention trial. Vox Sanguinis, 103(1), 25-34. https://doi.org/10.1111/j.1423-0410.2011.01575.x
  • 2011
    • Kilinc, E., Schulz, H., Kuiper, G. J. A. J. M., Spronk, H. M. H., ten Cate, H., Upadhyay, S., Ganguly, K., Stoeger, T., Semmler-Bhenke, M., Takenaka, S., Kreyling, W. G., Pitz, M., Reitmeir, P., Peters, A., Eickelberg, O., & Wichmann, H. E. (2011). The procoagulant effects of fine particulate matter in vivo. Particle and Fibre Toxicology, 8, 3. https://doi.org/10.1186/1743-8977-8-12
    • Kuiper, G. J. A. J. M., Lance, M. D., Smit-Fun, V. M., Peeters, L. L. H., & Marcus, M. A. E. (2011). Platelet monitoring follow-up in a pregnant patient with HELLP syndrome. Platelets, 22(2), 160-163. https://doi.org/10.3109/09537104.2010.528088