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Team Science grant Uyen Nguyen and Roel Meiburg

Team Science grant Uyen Nguyen and Roel Meiburg

18 December 2024

Dr Uyen Nguyen (Dept of Cardiology) and Dr Roel Meiburg (Biomedical Engineer, TU Eindhoven) have been awarded a Dekker Team Science grant by the Dutch Heart Foundation.

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ZonMw grant on appropriate palliative care

ZonMw grant on appropriate palliative care

10 December 2024

Prof. Marc Hemmelder (Dept of Internal Medicine) and his team received a ZonMw grant to promote early palliative care for dialysis patients who are non-waitlisted for transplantation.
 

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Carim Maastricht
Carim Maastricht

Christian Weber

Professor

Prof. Christian Weber is the Chair in Vascular Medicine and the Director of the Institute for Cardiovascular Prevention at Ludwig-Maximilians-University (LMU) Munich, Germany, and Professor at the CARIM. After graduating and completing his training in internal medicine at LMU and Harvard Medical School, Boston, he was board-certified in clinical cardiology and appointed as a Chair in Molecular Cardiology at RWTH Aachen University. His group has a strong interest in the molecular interactions and patho-physiological functions of chemokines and immune cell subsets, as well as the role of microRNAs and their targets in vascular disease and atherosclerosis, while his clinical interests focus on developing novel biomarkers and biopharmaceuticals. He is the Spokesman of the DFG Collaborative Research Centre SFB1123 and coordinates the partner site Munich Heart Alliance in the German Centre for Cardiovascular Research (DZHK). Among numerous awards, he is a double ERC Advanced Investigator Grant recipient and Clarivate Analytics Highly Cited Researcher with more than 560 publications and an h-index of 97. He serves as the Editor-in-Chiefof Thrombosis&Haemostasis, Senior Associate Editor of Arteriosclerosis, Thrombosis & Vascular Biology andco-founderofCarolusTherapeutics Inc. and Cartesio Therapeutics Inc.

  • Vascular Immunotherapy, German Centre for Cardiovascular Research (BMBF DZHK
  • MHA VD1.2), 2019-2020
  • Munich Cluster for Systems Neurology (SyNergy), DFG Excellence Initiative, 2019-2026
  • ERC Advanced Grant °692511, PROVASC: Cell-specific vascular protection by CXCL12/CXCR4, 2016- 2022 ERC AdG
  • NIH 1R01HL122843, Molecular mechanisms linking CXCL12 to atherosclerosis, 2017-2020
  • DFG Collaborative Research Centre 1123 Atherosclerosis: new therapeutic targets, 2014-2022
Christian-weber

Department of Biochemistry
Universiteitssingel 50, 6229 ER Maastricht
PO Box 616, 6200 MD Maastricht

  • 2018
    • Rami, M., Guillamat-Prats, R., Rinne, P., Salvermoser, M., Ring, L., Bianchini, M., Blanchet, X., Megens, R. T. A., Doring, Y., Walzog, B., Soehnlein, O., Weber, C., Faussner, A., & Steffens, S. (2018). Chronic Intake of the Selective Serotonin Reuptake Inhibitor Fluoxetine Enhances Atherosclerosis. Arteriosclerosis Thrombosis and Vascular Biology, 38(5), 1007-1019. https://doi.org/10.1161/ATVBAHA.117.310536
    • Lacy, M., Kontos, C., Brandhofer, M., Hille, K., Groning, S., Sinitski, D., Bourilhon, P., Rosenberg, E., Krammer, C., Thavayogarajah, T., Pantouris, G., Bakou, M., Weber, C., Lolis, E., Bernhagen, J., & Kapurniotu, A. (2018). Identification of an Arg-Leu-Arg tripeptide that contributes to the binding interface between the cytokine MIF and the chemokine receptor CXCR4. Scientific Reports, 8(1), Article 5171. https://doi.org/10.1038/s41598-018-23554-5
    • Horckmans, M., Bianchini, M., Santovito, D., Megens, R. T. A., Springael, J.-Y., Negri, I., Vacca, M., Di Eusanio, M., Moschetta, A., Weber, C., Duchene, J., & Steffens, S. (2018). Pericardial Adipose Tissue Regulates Granulopoiesis, Fibrosis, and Cardiac Function After Myocardial Infarction. Circulation, 137(9), 948-960. https://doi.org/10.1161/CIRCULATIONAHA.117.028833
    • Seijkens, T. T. P., van Tiel, C. M., Kusters, P. J. H., Atzler, D., Soehnlein, O., Zarzycka, B., Aarts, S. A. B. M., Lameijer, M., Gijbels, M. J., Beckers, L., den Toom, M., Slutter, B., Kuiper, J., Duchene, J., Aslani, M., Megens, R. T. A., van 't Veer, C., Kooij, G., Schrijver, R., ... Lutgens, E. (2018). Targeting CD40-Induced TRAF6 Signaling in Macrophages Reduces Atherosclerosis. Journal of the American College of Cardiology, 71(5), 527-542. https://doi.org/10.1016/j.jacc.2017.11.055
    • Ebrahim, M., Jamasbi, J., Adler, K., Megens, R. T. A., M'Bengue, Y., Blanchet, X., Uhland, K., Ungerer, M., Brandl, R., Weber, C., Elia, N., Lorenz, R., Muench, G., & Siess, W. (2018). Dimeric Glycoprotein VI Binds to Collagen but Not to Fibrin. Thrombosis and Haemostasis, 118(2), 351-361. https://doi.org/10.1160/TH17-04-0302
    • Curaj, A., Wu, Z., Rix, A., Gresch, O., Sternkopf, M., Alampour-Rajabi, S., Lammers, T., van Zandvoort, M., Weber, C., Koenen, R. R., Liehn, E. A., & Kiessling, F. (2018). Molecular Ultrasound Imaging of Junctional Adhesion Molecule A Depicts Acute Alterations in Blood Flow and Early Endothelial Dysregulation. Arteriosclerosis Thrombosis and Vascular Biology, 38(1), 40-48. https://doi.org/10.1161/ATVBAHA.117.309503
  • 2017
    • Winkels, H., Meiler, S., Lievens, D., Engel, D., Spitz, C., Buerger, C., Beckers, L., Dandl, A., Reim, S., Ahmadsei, M., Hartwig, H., Holdt, L. M., Hristov, M., Megens, R. T. A., Schmitt, M. M., Biessen, E. A., Borst, J., Faussner, A., Weber, C., ... Gerdes, N. (2017). CD27 co-stimulation increases the abundance of regulatory T cells and reduces atherosclerosis in hyperlipidaemic mice. European Heart Journal, 38(48), 3590-3599. https://doi.org/10.1093/eurheartj/ehx517
    • Kusters, P., Seijkens, T., Buerger, C., Legein, B., Winkels, H., Gijbels, M., Barthels, C., Bennett, R., Beckers, L., Atzler, D., Biessen, E., Brocker, T., Weber, C., Gerdes, N., & Lutgenst, E. (2017). Constitutive CD40 Signaling in Dendritic Cells Limits Atherosclerosis by Provoking Inflammatory Bowel Disease and Ensuing Cholesterol Malabsorption. American Journal of Pathology, 187(12), 2912-2919. https://doi.org/10.1016/j.ajpath.2017.08.016
    • Wu, Z., Rademakers, T., Kiessling, F., Vogt, M., Westein, E., Weber, C., Megens, R. T. A., & van Zandvoort, M. (2017). Multi-photon microscopy in cardiovascular research. Methods, 130, 79-89. https://doi.org/10.1016/j.ymeth.2017.04.013
    • Weber, C., & von Hundelshausen, P. (2017). CANTOS Trial Validates the Inflammatory Pathogenesis of Atherosclerosis Setting the Stage for a New Chapter in Therapeutic Targeting. Circulation Research, 121(10), 1119-1121. https://doi.org/10.1161/CIRCRESAHA.117.311984
    • Krishnasamy, K., Limbourg, A., Kapanadze, T., Gamrekelashvili, J., Beger, C., Haeger, C., Lozanovski, V. J., Falk, C. S., Napp, L. C., Bauersachs, J., Mack, M., Haller, H., Weber, C., Adams, R. H., & Limbourg, F. P. (2017). Blood vessel control of macrophage maturation promotes arteriogenesis in ischemia. Nature Communications, 8(1), Article 952. https://doi.org/10.1038/s41467-017-00953-2
    • Theodorou, K., van der Vorst, E. P. C., Gijbels, M. J., Wolfs, I. M. J., Jeurissen, M., Theelen, T. L., Sluimer, J. C., Wijnands, E., Cleutjens, J. P., Li, Y., Jansen, Y., Weber, C., Ludwig, A., Bentzon, J. F., Bartsch, J. W., Biessen, E. A. L., & Donners, M. M. P. C. (2017). Whole body and hematopoietic ADAM8 deficiency does not influence advanced atherosclerotic lesion development, despite its association with human plaque progression. Scientific Reports, 7(1), Article 11670. https://doi.org/10.1038/s41598-017-10549-x
    • Schloss, M. J., Hilby, M., Nitz, K., Prats, R. G., Ferraro, B., Leoni, G., Soehnlein, O., Kessler, T., He, W., Luckow, B., Horckmans, M., Weber, C., Duchene, J., & Steffens, S. (2017). Ly6C(high) Monocytes Oscillate in the Heart During Homeostasis and After Myocardial Infarction-Brief Report. Arteriosclerosis Thrombosis and Vascular Biology, 37(9), 1640-1645. https://doi.org/10.1161/ATVBAHA.117.309259
    • Zhao, Z., Vajen, T., Karshovska, E., Dickhout, A., Schmitt, M. M., Megens, R. T. A., von Hundelshausen, P., Koeppel, T. A., Hackeng, T. M., Weber, C., & Koenen, R. R. (2017). Deletion of junctional adhesion molecule A from platelets increases early-stage neointima formation after wire injury in hyperlipidemic mice. Journal of Cellular and Molecular Medicine, 21(8), 1523-1531. https://doi.org/10.1111/jcmm.13083
    • Munoz, A.-K. M., Jamasbi, J., Uhland, K., Degen, H., Muench, G., Ungerer, M., Brandl, R., Megens, R., Weber, C., Lorenz, R., & Siess, W. (2017). Recombinant GPVI-Fc added to single or dual antiplatelet therapy in vitro prevents plaque-induced platelet thrombus formation. Thrombosis and Haemostasis, 117(8), 1651-1659. https://doi.org/10.1160/TH16-11-0856
    • Doring, Y., Noels, H., van der Vorst, E. P. C., Neideck, C., Egea, V., Drechsler, M., Mandl, M., Pawig, L., Jansen, Y., Schroeder, K., Bidzhekov, K., Megens, R. T. A., Theelen, W., Klinkhammer, B. M., Boor, P., Schurgers, L., van Gorp, R., Ries, C., Kusters, P. J. H., ... Weber, C. (2017). Vascular CXCR4 Limits Atherosclerosis by Maintaining Arterial Integrity Evidence From Mouse and Human Studies. Circulation, 136(4), 388-403. https://doi.org/10.1161/CIRCULATIONAHA.117.027646
    • Duchene, J., Novitzky-Basso, I., Thiriot, A., Casanova-Acebes, M., Bianchini, M., Etheridge, S. L., Hub, E., Nitz, K., Artinger, K., Eller, K., Caamano, J., Rulicke, T., Moss, P., Megens, R. T. A., von Andrian, U. H., Hidalgo, A., Weber, C., & Rot, A. (2017). Atypical chemokine receptor 1 on nucleated erythroid cells regulates hematopoiesis. Nature Immunology, 18(7), 753-761. https://doi.org/10.1038/ni.3763
    • Ridger, V. C., Boulanger, C. M., Angelillo-Scherrer, A., Badimon, L., Blanc-Brude, O., Bochaton-Piallat, M.-L., Boilard, E., Buzas, E. I., Caporali, A., Dignat-George, F., Evans, P. C., Lacroix, R., Lutgens, E., Ketelhuth, D. F. J., Nieuwland, R., Toti, F., Tunon, J., Weber, C., Hoefer, I. E., ... Harrison, P. (2017). Microvesicles in vascular homeostasis and diseases Position Paper of the European Society of Cardiology (ESC) Working Group on Atherosclerosis and Vascular Biology. Thrombosis and Haemostasis, 117(7), 1296-1316. https://doi.org/10.1160/TH16-12-0943
    • Weber, C., Badimon, L., Mach, F., & van der Vorst, E. P. C. (2017). Therapeutic strategies for atherosclerosis and atherothrombosis: Past, present and future. Thrombosis and Haemostasis, 117(7), 1258-1264. https://doi.org/10.1160/TH16-10-0814
    • van der Vorst, E. P. C., Maas, S. L., Ortega-Gomez, A., Hameleers, J. M. M., Bianchini, M., Asare, Y., Soehnlein, O., Döring, Y., Weber, C., & Megens, R. T. A. (2017). Functional Imaging of Arterial Cellular Recruitment and Lipid Extravasation. Bio-protocol, 7(12). https://doi.org/10.21769/BioProtoc.2344
    • Steffens, S., Winter, C., Schloss, M. J., Hidalgo, A., Weber, C., & Soehnlein, O. (2017). Circadian Control of Inflammatory Processes in Atherosclerosis and Its Complications. Arteriosclerosis Thrombosis and Vascular Biology, 37(6), 1022-1028. https://doi.org/10.1161/ATVBAHA.117.309374
    • Aarts, S. A. B. M., Seijkens, T. T. P., Kusters, P. J. H., van der Pol, S. M. A., Zarzycka, B., Heijnen, P. D. A. M., Beckers, L., den Toom, M., Gijbels, M. J. J., Boon, L., Weber, C., de Vries, H. E., Nicolaes, G. A. F., Dijkstra, C. D., Kooij, G., & Lutgens, E. (2017). Inhibition of CD40-TRAF6 interactions by the small molecule inhibitor 6877002 reduces neuroinflammation. Journal of Neuroinflammation, 14(1), Article 105. https://doi.org/10.1186/s12974-017-0875-9
    • von Hundelshausen, P., Agten, S. M., Eckardt, V., Blanchet, X., Schmitt, M. M., Ippel, H., Neideck, C., Bidzhekov, K., Leberzammer, J., Wichapong, K., Faussner, A., Drechsler, M., Grommes, J., van Geffen, J. P., Li, H., Ortega-Gomez, A., Megens, R. T. A., Naumann, R., Dijkgraaf, I., ... Weber, C. (2017). Chemokine interactome mapping enables tailored intervention in acute and chronic inflammation. Science Translational Medicine, 9(384), Article eaah6650. https://doi.org/10.1126/scitranslmed.aah6650
    • Soehnlein, O., Steffens, S., Hidalgo, A., & Weber, C. (2017). Neutrophils as protagonists and targets in chronic inflammation. Nature Reviews Immunology, 17(4), 248-261. https://doi.org/10.1038/nri.2017.10
    • Asare, Y., Ommer, M., Azombo, F. A., Alampour-Rajabi, S., Sternkopf, M., Sanati, M., Gijbels, M. J., Schmitz, C., Sinitski, D., Tilstam, P. V., Lue, H., Gessner, A., Lange, D., Schmid, J. A., Weber, C., Dichgans, M., Jankowski, J., Pardi, R., de Winther, M. P. J., ... Bernhagen, J. (2017). Inhibition of atherogenesis by the COP9 signalosome subunit 5 in vivo. Proceedings of the National Academy of Sciences of the United States of America, 114(13), E2766-E2775. https://doi.org/10.1073/pnas.1618411114
    • Hyafil, F., Pelisek, J., Laitinen, I., Schottelius, M., Mohring, M., Doering, Y., van der Vorst, E. P. C., Kallmayer, M., Steiger, K., Poschenrieder, A., Notni, J., Fischer, J., Baumgartner, C., Rischpler, C., Nekolla, S. G., Weber, C., Eckstein, H.-H., Wester, H.-J., & Schwaiger, M. (2017). Imaging the Cytokine Receptor CXCR4 in Atherosclerotic Plaques with the Radiotracer (68)Ga-Pentixafor for PET. Journal of Nuclear Medicine, 58(3), 499-506. https://doi.org/10.2967/jnumed.116.179663
    • van der Vorst, E. P. C., Zhao, Z., Rami, M., Holdt, L. M., Teupser, D., Steffens, S., & Weber, C. (2017). Contrasting effects of myeloid and endothelial ADAM17 on atherosclerosis development. Thrombosis and Haemostasis, 117(3), 644-646. https://doi.org/10.1160/TH16-09-0674
    • Rowinska, Z., Koeppel, T. A., Sanati, M., Schelzig, H., Jankowski, J., Weber, C., Zernecke, A., & Liehn, E. A. (2017). Role of the CX3C chemokine receptor CX3CR1 in the pathogenesis of atherosclerosis after aortic transplantation. PLOS ONE, 12(2), Article 0170644. https://doi.org/10.1371/journal.pone.0170644
    • Wolf, D., Bukosza, N., Enge, D., Poggi, M., Jehle, F., Michel, N. A., Chen, Y.-C., Colberg, C., Hoppe, N., Dufner, B., Boon, L., Blankenbach, H., Hilgendorf, I., Muhlen, C. V. Z., Reinoehl, J., Sommer, B., Marchini, T., Febbraio, M. A., Weber, C., ... Zirlik, A. (2017). Inflammation, but not recruitment, of adipose tissue macrophages requires signalling through Mac-1 (CD11b/CD18) in diet-induced obesity (DIO). Thrombosis and Haemostasis, 117(2), 325-338. https://doi.org/10.1160/TH16-07-0553
    • Doering, Y., Soehnlein, O., & Weber, C. (2017). Neutrophil Extracellular Traps in Atherosclerosis and Atherothrombosis. Circulation Research, 120(4), 736-743. https://doi.org/10.1161/CIRCRESAHA.116.309692
    • de Jong, R. J., Paulin, N., Lemnitzer, P., Viola, J. R., Winter, C., Ferraro, B., Grommes, J., Weber, C., Reutelingsperger, C., Drechsler, M., & Soehnlein, O. (2017). Protective Aptitude of Annexin A1 in Arterial Neointima Formation in Atherosclerosis-Prone Mice-Brief Report. Arteriosclerosis Thrombosis and Vascular Biology, 37(2), 312-315. https://doi.org/10.1161/ATVBAHA.116.308744
    • Winkels, H., Meiler, S., Smeets, E., Lievens, D., Engel, D., Spitz, C., Buerger, C., Rinne, P., Beckers, L., Dandl, A., Reim, S., Ahmadsei, M., Van den Bossche, J., Holdt, L. M., Megens, R. T. A., Schmitt, M. M., de Winther, M., Biessen, E. A., Borst, J., ... Gerdes, N. (2017). CD70 limits atherosclerosis and promotes macrophage function. Thrombosis and Haemostasis, 117(1), 164-175. https://doi.org/10.1160/TH16-04-0318
    • Zahedi, F., Nazari-Jahantigh, M., Zhou, Z., Subramanian, P., Wei, Y., Grommes, J., Offermanns, S., Steffens, S., Weber, C., & Schober, A. (2017). Dicer generates a regulatory microRNA network in smooth muscle cells that limits neointima formation during vascular repair. Cellular and Molecular Life Sciences, 74(2), 359-372. https://doi.org/10.1007/s00018-016-2349-0
  • 2016
    • Chubanov, V., Ferioli, S., Wisnowsky, A., Simmons, D. G., Leitzinger, C., Einer, C., Jonas, W., Shymkiv, Y., Bartsch, H., Braun, A., Akdogan, B., Mittermeier, L., Sytik, L., Torben, F., Jurinovic, V., van der Vorst, E. P. C., Weber, C., Yildirim, O. A., Sotlar, K., ... Gudermann, T. (2016). Epithelial magnesium transport by TRPM6 is essential for prenatal development and adult survival. Elife, 5(DECEMBER2016), Article e20914. https://doi.org/10.7554/eLife.20914
    • Agten, S. M., Koenen, R. R., Ippel, H., Eckardt, V., von Hundelshausen, P., Mayo, K. H., Weber, C., & Hackeng, T. M. (2016). Probing Functional Heteromeric Chemokine Protein-Protein Interactions through Conformation-Assisted Oxime Ligation. Angewandte Chemie-International Edition, 55(48), 14963-14966. https://doi.org/10.1002/anie.201607036
    • Finan, B., Clemmensen, C., Zhu, Z., Stemmer, K., Gauthier, K., Mueller, L., De Angelis, M., Moreth, K., Neff, F., Perez-Tilve, D., Fischer, K., Lutter, D., Sanchez-Garrido, M. A., Liu, P., Tuckermann, J., Malehmir, M., Healy, M. E., Weber, A., Heikenwalder, M., ... Mueller, T. D. (2016). Chemical Hybridization of Glucagon and Thyroid Hormone Optimizes Therapeutic Impact for Metabolic Disease. Cell, 167(3), 843-857. https://doi.org/10.1016/j.cell.2016.09.014
    • Ortega-Gomez, A., Salvermoser, M., Rossaint, J., Pick, R., Brauner, J., Lemnitzer, P., Tilgner, J., de Jong, R. J., Megens, R. T. A., Jamasbi, J., Doering, Y., Pham, C. T., Scheiermann, C., Siess, W., Drechsler, M., Weber, C., Grommes, J., Zarbock, A., Walzog, B., & Soehnlein, O. (2016). Cathepsin G Controls Arterial But Not Venular Myeloid Cell Recruitment. Circulation, 134(16), 1176-1188. https://doi.org/10.1161/CIRCULATIONAHA.116.024790
    • Gamrekelashvili, J., Giagnorio, R., Jussofie, J., Soehnlein, O., Duchene, J., Briseno, C. G., Ramasamy, S. K., Krishnasamy, K., Limbourg, A., Kapanadze, T., Ishifune, C., Hinkel, R., Radtke, F., Strobl, L. J., Zimber-Strobl, U., Napp, L. C., Bauersachs, J., Haller, H., Yasutomo, K., ... Limbourg, F. P. (2016). Regulation of monocyte cell fate by blood vessels mediated by Notch signalling. Nature Communications, 7, Article 12597. https://doi.org/10.1038/ncomms12597
    • Schloss, M. J., Horckmans, M., Nitz, K., Duchene, J., Drechsler, M., Bidzhekov, K., Scheiermann, C., Weber, C., Soehnlein, O., & Steffens, S. (2016). The time-of-day of myocardial infarction onset affects healing through oscillations in cardiac neutrophil recruitment. EMBO Molecular Medicine, 8(8), 937-948. https://doi.org/10.15252/emmm.201506083
    • Simsekyilmaz, S., Liehn, E. A., Weinandy, S., Schreiber, F., Megens, R. T. A., Theelen, W., Smeets, R., Jockenhoevel, S., Gries, T., Moeller, M., Klee, D., Weber, C., & Zernecke, A. (2016). Targeting In-Stent-Stenosis with RGD- and CXCL1-Coated Mini-Stents in Mice. PLOS ONE, 11(5), Article e0155829. https://doi.org/10.1371/journal.pone.0155829
    • Wichapong, K., Alard, J. .-E., Ortega-Gomez, A., Weber, C., Hackeng, T. M., Soehnlein, O., & Nicolaes, G. A. F. (2016). Structure-Based Design of Peptidic Inhibitors of the Interaction between CC Chemokine Ligand 5 (CCL5) and Human Neutrophil Peptides 1 (HNP1). Journal of Medicinal Chemistry, 59(9), 4289-4301. https://doi.org/10.1021/acs.jmedchem.5b01952
    • Weber, C., Doering, Y., & Noels, H. (2016). Potential cell-specific functions of CXCR4 in atherosclerosis. Hämostaseologie, 36(2), 97-102. https://doi.org/10.5482/HAMO-14-10-0054
    • Mahl, C., Egea, V., Megens, R. T. A., Pitsch, T., Santovito, D., Weber, C., & Ries, C. (2016). RECK (reversion-inducing cysteine-rich protein with Kazal motifs) regulates migration, differentiation and Wnt/beta-catenin signaling in human mesenchymal stem cells. Cellular and Molecular Life Sciences, 73(7), 1489-1501. https://doi.org/10.1007/s00018-015-2054-4
    • Gerdes, N., Seijkens, T., Lievens, D., Kuijpers, M. J. E., Winkels, H., Projahn, D., Hartwig, H., Beckers, L., Megens, R. T. A., Boon, L., Noelle, R. J., Soehnlein, O., Heemskerk, J. W. M., Weber, C., & Lutgens, E. (2016). Platelet CD40 Exacerbates Atherosclerosis by Transcellular Activation of Endothelial Cells and Leukocytes. Arteriosclerosis Thrombosis and Vascular Biology, 36(3), 482-490. https://doi.org/10.1161/ATVBAHA.115.307074
    • Hartmann, P., Zhou, Z., Natarelli, L., Wei, Y., Nazari-Jahantigh, M., Zhu, M., Grommes, J., Steffens, S., Weber, C., & Schober, A. (2016). Endothelial Dicer promotes atherosclerosis and vascular inflammation by miRNA-103-mediated suppression of KLF4. Nature Communications, 7, Article 10521. https://doi.org/10.1038/ncomms10521
    • Jamasbi, J., Megens, R. T. A., Bianchini, M., Uhland, K., Münch, G., Ungerer, M., Sherman, S., Faussner, A., Brandl, R., John, C., Buchner, J., Weber, C., Lorenz, R., Elia, N., & Siess, W. (2016). Cross-Linking GPVI-Fc by Anti-Fc Antibodies Potentiates Its Inhibition of Atherosclerotic Plaque- and Collagen-Induced Platelet Activation. JACC: Basic to Translational Science, 1(3), 131 – 142. https://doi.org/10.1016/j.jacbts.2016.03.008
  • 2015
    • Alard, J.-E., Ortega-Gomez, A., Wichapong, K., Bongiovanni, D., Horckmans, M., Megens, R. T. A., Leoni, G., Ferraro, B., Rossaint, J., Paulin, N., Ng, J., Ippel, H., Suylen, D., Hinkel, R., Blanchet, X., Gaillard, F., D'Amico, M., von Hundelshausen, P., Zarbock, A., ... Soehnlein, O. (2015). Recruitment of classical monocytes can be inhibited by disturbing heteromers of neutrophil HNP1 and platelet CCL5. Science Translational Medicine, 7(317), Article 317ra196. https://doi.org/10.1126/scitranslmed.aad5330
    • Akhtar, S., Hartmann, P., Karshovska, E., Rinderknecht, F.-A., Subramanian, P., Gremse, F., Grommes, J., Jacobs, M., Kiessling, F., Weber, C., Steffens, S., & Schober, A. (2015). Endothelial Hypoxia-Inducible Factor-1 alpha Promotes Atherosclerosis and Monocyte Recruitment by Upregulating MicroRNA-19a. Hypertension, 66(6), 1220-1226. https://doi.org/10.1161/HYPERTENSIONAHA.115.05886
    • van der Vorst, E. P. C., Doering, Y., & Weber, C. (2015). Chemokines. Arteriosclerosis Thrombosis and Vascular Biology, 35(11), E52-E56. https://doi.org/10.1161/ATVBAHA.115.306359
    • Alampour-Rajabi, S., El Bounkari, O., Rot, A., Mueller-Newen, G., Bachelerie, F., Gawaz, M., Weber, C., Schober, A., & Bernhagen, J. (2015). MIF interacts with CXCR7 to promote receptor internalization, ERK1/2 and ZAP-70 signaling, and lymphocyte chemotaxis. Faseb Journal, 29(11), 4497-4511. https://doi.org/10.1096/fj.15-273904
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