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ZonMw grant Middellange termijn effecten van COVID-19 maatregelen

ZonMw grant Middellange termijn effecten van COVID-19 maatregelen

20 August 2024

The project 'Impact of COVID-19 protective measures and shielding in vulnerable patients with kidney failure', coordinated by Prof. Marc Hemmelder and Drs Pim Bouwmans (Dept of Internal Medicine), has been granted by ZonMw. 

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Professorship Henri Spronk

Professorship Henri Spronk

12 August 2024

Dr Henri Spronk (Dept of Biochemistry) has been appointed as professor of ‘Biochemistry of Atherothrombosis’ as of 1 May 2024.

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Carim Maastricht
Carim Maastricht

Stephane Heymans

Professor

Stephane Heymans is Professor of Cardiomyopathies and Head of the Centre for Heart Failure Research, Department of Cardiology, Maastricht University. He obtained his Medical Degree from the KU Leuven (Belgium) in 1995 and went on to get a PhD in Medical Sciences in 2000, studying the role of proteinases in acute myocardial infarction. In 2003, he joined the Department of Cardiology of Maastricht UMC+ as an academic medical specialist and in 2006 he took over the Multidisciplinary Cardiomyopathy Program (Genetics, Immunology, Microbiology and Pathology departments).

In 2008, he established his independent research laboratory at Cardiovascular Research Institute Maastricht. His research interests focus on the molecular mechanisms of heart failure, looking at the interplay between inflammatory cells, fibroblasts and cardiomyocytes. Particular focus is on the role of non-structural matrix proteins, matrix turnover and non-coding RNAs.

Furthermore, he is Professor of 'Inflammation and Matrix Biology in Cardiomyopathies' at the University of Leuven and he is a board member of the ESC Heart Failure Association, ESC Working Group of Myocardial Function, ESC Heart Failure Association Committee on Diastolic Heart Failure and ESC Heart Failure Association Committee on Translational Research.

Website www.hfresearch.eu

Stephane-heymans

Department of Cardiology
Universiteitssingel 50, 6229 ER Maastricht
PO Box 616, 6200 MD Maastricht
Room number: G3.230
T: +31(0)43 388 43 04

  • 2024
    • Wei, F.-F., Mariottoni, B., An, D.-W., Pellicori, P., Yu, Y.-L., Verdonschot, J. A. J., Liu, C., Ahmed, F. Z., Petutschnigg, J., Rossignol, P., Heymans, S., Cuthbert, J., Girerd, N., Li, Y., Clark, A. L., Nawrot, T. S., Ferreira, J. P., Zannad, F., Cleland, J. G. F., ... HOMAGE investigators (2024). Heart rate reactivity, recovery, and endurance of the incremental shuttle walk test in patients prone to heart failure. Esc heart failure. Advance online publication. https://doi.org/10.1002/ehf2.15000
    • Beijnink, C. W. H., Raafs, A. G., Vos, J. L., Verdonschot, J. A. J., Sikking, M. A., Rodwell, L., Heymans, S. R. B., & Nijveldt, R. (2024). Papillary Muscle Delayed Hyperenhancement: Prevalence and Clinical Implications in a Large Population With Dilated Cardiomyopathy. JACC: Advances, 3(8), Article 101103. https://doi.org/10.1016/j.jacadv.2024.101103
    • Machiraju, P., Srinivas, R., Kannan, R., George, R., Heymans, S., Mukhopadhyay, R., & Ghosh, A. (2024). Paired Transcriptomic Analyses of Atheromatous and Control Vessels Reveal Novel Autophagy and Immunoregulatory Genes in Peripheral Artery Disease. Cells, 13(15), Article 1269. https://doi.org/10.3390/cells13151269
    • Heymans, S., Van Linthout, S., Kraus, S. M., Cooper, L. T., & Ntusi, N. A. B. (2024). Clinical Characteristics and Mechanisms of Acute Myocarditis. Circulation Research, 135(2), 397-411. https://doi.org/10.1161/CIRCRESAHA.124.324674
    • Falcao-Pires, I., Ferreira, A. F., Trindade, F., Bertrand, L., Ciccarelli, M., Visco, V., Dawson, D., Hamdani, N., Van Laake, L. W., Lezoualc'h, F., Linke, W. A., Lunde, I. G., Rainer, P. P., Abdellatif, M., van der Velden, J., Cosentino, N., Paldino, A., Pompilio, G., Zacchigna, S., ... Tocchetti, C. G. (2024). Mechanisms of myocardial reverse remodelling and its clinical significance: A scientific statement of the ESC Working Group on Myocardial Function. European journal of heart failure, 26(7), 1454-1479. https://doi.org/10.1002/ejhf.3264
    • Wiethoff, I., Sikking, M., Evers, S., Gabrio, A., Henkens, M., Michels, M., Verdonschot, J., Heymans, S., & Hiligsmann, M. (2024). Quality of life and societal costs in patients with dilated cardiomyopathy. European heart journal - Quality of care & clinical outcomes, 10(4), 334-344. Article qcad056. https://doi.org/10.1093/ehjqcco/qcad056
    • Yu, Y.-L., Siwy, J., An, D.-W., González, A., Hansen, T., Latosinska, A., Pellicori, P., Ravassa, S., Mariottoni, B., Verdonschot, J. A., Ahmed, F., Petutschnigg, J., Rossignol, P., Heymans, S., Cuthbert, J. J., Girerd, N., Clark, A. L., Verhamme, P., Nawrot, T. S., ... HOMAGE investigators (2024). Urinary proteomic signature of mineralocorticoid receptor antagonism by spironolactone: evidence from the HOMAGE trial. Heart, Article heartjnl-2023-323796. Advance online publication. https://doi.org/10.1136/heartjnl-2023-323796
    • Sikking, M. A., Stroeks, S. L. V. M., Henkens, M. T. H. M., Raafs, A. G., Cossins, B., van Deuren, R. C., Steehouwer, M., Riksen, N. P., van den Wijngaard, A., Brunner, H. G., Hoischen, A., Verdonschot, J. A. J., & Heymans, S. R. B. (2024). Clonal Hematopoiesis has Prognostic Value in Dilated Cardiomyopathy independent of Age and Clone Size. JACC: Heart Failure, 12(5), 905-914. https://doi.org/10.1016/j.jchf.2023.06.037
    • Kobayashi, M., Ferreira, J. P., Kevin, D., Bresso, E., Huttin, O., Bozec, E., Brunner La Rocca, H.-P., Delles, C., Clark, A. L., Edelmann, F., González, A., Heymans, S., Pellicori, P., Petutschnigg, J., Verdonschot, J. A. J., Rossignol, P., Cleland, J. G. F., Zannad, F., Girerd, N., & HOMAGE Trial Committees and Investigators (2024). Proteomic profiles of left atrial volume and its influence on response to spironolactone: Findings from the HOMAGE trial and STANISLAS cohort. European journal of heart failure, 26(5), 1231-1241. https://doi.org/10.1002/ejhf.3202
    • Weerts, J., Raafs, A. G., Sandhoefner, B., van der Heide, F. C. T., Mourmans, S. G. J., Wolff, N., Finger, R. P., Falahat, P., Wintergerst, M. W. M., van Empel, V. P. M., & Heymans, S. R. B. (2024). Retinal Vascular Changes in Heart Failure with Preserved Ejection Fraction Using Optical Coherence Tomography Angiography. Journal of Clinical Medicine, 13(7), Article 1892. https://doi.org/10.3390/jcm13071892
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