Dominik Linz

Professor

Prof Dominik Linz is a clinician-scientist who received his PhD from Maastricht University, The Netherlands, in 2013 (Prof. U. Schotten) and completed his Cardiology training in Homburg/Saar, Germany, in 2017 (Prof. M. Böhm). In 2017, he was recruited as an Associate Professor and clinical EP-fellow to Adelaide to initiate and drive a translational research programme focussing on atrial fibrillation and sleep disordered breathing at the Royal Adelaide Hospital and University of Adelaide (Prof. P. Sanders). Since 2019, Dr Dominik Linz is a Staff member and consultant clinician at the Heart+Vascular Center, Maastricht UMC+.

Over the past years Prof. Dominik Linz has developed a National and International reputation in the field of cardiac arrhythmia research. The focus of this work has been to understand the pathophysiology and mechanisms underlying atrial arrhythmias and the development of treatment approaches. This research has broadly included: (i) Work describing sleep apnoea associated electrophysiological changes in the atria increasing atrial fibrillation susceptibility. (ii) Description of antiarrhythmic effects of autonomic modulation by renal sympathetic denervation under different pathophysiological conditions. (iii) Work describing the role of the lysosomal carboxypeptidase cathepsin A in the development of an atrial arrhythmogenic substrates. Ongoing research is mainly focused on risk factor modification and preventive interventions for AF.

As of January 2024, Dominik Linz (Department of Cardiology) has been appointed as a professor at Maastricht University. The title of his position is 'Comprehensive Atrial Fibrillation Management.

Department of Cardiology

 

  • 2024
    • Malik, V., Linz, D., & Sanders, P. (2024). The Role of the Autonomic Nervous System as Both “Trigger and “Substrate” in Atrial Fibrillation. Cardiac Electrophysiology Clinics, 16(3), 271-280. https://doi.org/10.1016/j.ccep.2023.08.003
    • Shahrbabaki, S. S., Dharmaprani, D., Tiver, K. D., Jenkins, E., Strong, C., Tonchev, I., O'Loughlin, L. P., Linz, D., Chapman, D., Lechat, B., Ullah, S., Stone, K. L., Eckert, D. J., Baumert, M., & Ganesan, A. N. (2024). Power-law properties of nocturnal arrhythmia avalanches: a novel marker for incident cardiovascular events. Heart Rhythm. Advance online publication. https://doi.org/10.1016/j.hrthm.2024.08.015
    • Gilbers, M. D., Kawczynski, M. J., Bidar, E., Maesen, B., Isaacs, A., Winters, J., Linz, D., Rienstra, M., van Gelder, I., Maessen, J. G., & Schotten, U. (2024). Determinants and impact of postoperative atrial fibrillation burden during 2.5 years of continuous rhythm monitoring after cardiac surgery. Heart Rhythm. Advance online publication. https://doi.org/10.1016/j.hrthm.2024.08.014
    • Linz, D., & Dobrev, D. (2024). Recent highlights from the International Journal of Cardiology heart & Vasculature: Comprehensive management of atrial fibrillation. IJC Heart and Vasculature, 53, Article 101478. https://doi.org/10.1016/j.ijcha.2024.101478
    • Linz, D., & Hermans, B. J. M. (2024). Remote technical support of nurse-lead electro-anatomic mapping during complex catheter ablation procedures. European Journal of Cardiovascular Nursing. Advance online publication. https://doi.org/10.1093/eurjcn/zvae108
    • Chaldoupi, S.-M., Nissen, S. D., Vriesendorp, P. A., Jerltorp, K., Farnir, F. I. P., Linz, B., Johannessen, A., Haugdal, M. A., Luermans, J. G. L. M., Saljic, A., Jespersen, T., Hansen, J., & Linz, D. (2024). Focal monopolar pulsed field ablation from within the great cardiac vein for idiopathic premature ventricular contractions after failed radiofrequency ablation. Heart Rhythm. Advance online publication. https://doi.org/10.1016/j.hrthm.2024.07.002
    • Linz, D., & Chaldoupi, S. M. (2024). Early Rhythm Management in Patients With Atrial Fibrillation: From Symptom Control to Adverse Outcome Reduction. JACC: Clinical Electrophysiology, 10(7), 1406-1408. https://doi.org/10.1016/j.jacep.2024.06.003
    • Calvert, P., Mills, M. T., Howarth, K., Aykara, S., Lunt, L., Brewer, H., Green, D., Green, J., Moore, S., Almutawa, J., Linz, D., Lip, G. Y. H., Todd, D., & Gupta, D. (2024). Remote rhythm monitoring using a photoplethysmography smartphone application after cardioversion for atrial fibrillation. European Heart Journal - Digital Health, 5(4), 461-468. Article ztae028. https://doi.org/10.1093/ehjdh/ztae028
    • Ekanem, E., Neuzil, P., Reichlin, T., Kautzner, J., van der Voort, P., Jais, P., Chierchia, G. B., Bulava, A., Blaauw, Y., Skala, T., Fiala, M., Duytschaever, M., Szeplaki, G., Schmidt, B., Massoullie, G., Neven, K., Thomas, O., Vijgen, J., Gandjbakhch, E., ... Et al. (2024). Safety of pulsed field ablation in more than 17,000 patients with atrial fibrillation in the MANIFEST-17K study. Nature Medicine, 30(7), 2020-2029. https://doi.org/10.1038/s41591-024-03114-3
    • Wörmann, J., Strik, M., Jurisic, S., Stout, K., Elrefai, M., Becher, N., Schaer, B., van Stipdonk, A., Srinivasan, N. T., Ploux, S., Breitenstein, A., Kron, J., Roberts, P. R., Toennis, T., Linz, D., Dulai, R., Hermes-Laufer, J., Koneru, J., Erküner, Ö., ... Lüker, J. (2024). Occurrence of Premature Battery Depletion in a Large Multicenter Registry of Subcutaneous Cardioverter-Defibrillator Patients. EP Europace, 26(7), Article euae170. https://doi.org/10.1093/europace/euae170